Published in J Biol Chem on August 18, 2005
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev (2006) 14.36
Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci U S A (2008) 2.39
Chondrocyte BMP2 signaling plays an essential role in bone fracture healing. Gene (2012) 1.56
BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. J Cell Sci (2011) 1.44
Stem cell property of postmigratory cranial neural crest cells and their utility in alveolar bone regeneration and tooth development. Stem Cells (2009) 1.18
Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing. Bone (2010) 1.09
Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells. Arthritis Res Ther (2008) 1.05
Microdeletion 20p12.3 involving BMP2 contributes to syndromic forms of cleft palate. Am J Med Genet A (2011) 0.94
Transgenic over-expression of growth differentiation factor 11 propeptide in skeleton results in transformation of the seventh cervical vertebra into a thoracic vertebra. Mol Reprod Dev (2010) 0.94
Bone morphogenetic proteins in craniofacial surgery: current techniques, clinical experiences, and the future of personalized stem cell therapy. J Biomed Biotechnol (2012) 0.87
Cleft palate in a multigenerational family with a microdeletion of 20p12.3 involving BMP2. Am J Med Genet A (2012) 0.86
Coordination of chondrogenesis and osteogenesis by hypertrophic chondrocytes in endochondral bone development. J Bone Miner Metab (2010) 0.86
Myoblast sensitivity and fibroblast insensitivity to osteogenic conversion by BMP-2 correlates with the expression of Bmpr-1a. BMC Musculoskelet Disord (2009) 0.85
Expression of genes for bone morphogenetic proteins BMP-2, BMP-4 and BMP-6 in various parts of the human skeleton. BMC Musculoskelet Disord (2007) 0.85
The effect of core decompression on local expression of BMP-2, PPAR-γ and bone regeneration in the steroid-induced femoral head osteonecrosis. BMC Musculoskelet Disord (2012) 0.84
Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem (2014) 0.82
BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells. PLoS One (2010) 0.81
Developmental Regulation of the Growth Plate and Cranial Synchondrosis. J Dent Res (2016) 0.81
Vascular Calcification and Stone Disease: A New Look towards the Mechanism. J Cardiovasc Dev Dis (2015) 0.80
Gli1 haploinsufficiency leads to decreased bone mass with an uncoupling of bone metabolism in adult mice. PLoS One (2014) 0.80
Bioactive factors for tissue regeneration: state of the art. Muscles Ligaments Tendons J (2012) 0.79
Cell-based gene therapy for repair of critical size defects in the rat fibula. J Cell Biochem (2011) 0.79
Non-apoptotic functions of caspase-7 during osteogenesis. Cell Death Dis (2014) 0.79
Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation. Nat Commun (2016) 0.78
Identification of Novel EZH2 Targets Regulating Osteogenic Differentiation in Mesenchymal Stem Cells. Stem Cells Dev (2016) 0.77
Physiological role of bone morphogenetic proteins in osteogenesis. J Bone Miner Metab (2006) 0.76
Haploinsufficiency and triploinsensitivity of the same 6p25.1p24.3 region in a family. BMC Med Genomics (2015) 0.76
Runx1 and Runx3 Are Downstream Effectors of Nanog in Promoting Osteogenic Differentiation of the Mouse Mesenchymal Cell Line C3H10T1/2. Cell Reprogram (2015) 0.75
Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors. PLoS One (2009) 0.75
Surface-mediated delivery of siRNA from fibrin hydrogels for knockdown of the BMP-2 binding antagonist noggin. Acta Biomater (2015) 0.75
Cloning, expression profiling and promoter functional analysis of Bone morphogenetic protein 6 and 7 in tongue sole (Cynoglossus semilaevis). Fish Physiol Biochem (2016) 0.75
Osthole Promotes Bone Fracture Healing through Activation of BMP Signaling in Chondrocytes. Int J Biol Sci (2017) 0.75
A large-area, flexible pressure sensor matrix with organic field-effect transistors for artificial skin applications. Proc Natl Acad Sci U S A (2004) 8.15
Suppression of aging in mice by the hormone Klotho. Science (2005) 8.11
Conformable, flexible, large-area networks of pressure and thermal sensors with organic transistor active matrixes. Proc Natl Acad Sci U S A (2005) 5.37
PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest (2004) 5.29
Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts. Cell (2007) 4.71
Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature (2002) 4.44
BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med (2008) 4.20
Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. Nat Med (2010) 3.59
Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study. J Bone Miner Metab (2009) 3.27
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nat Genet (2005) 3.00
Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat Cell Biol (2005) 2.56
Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development (2004) 2.39
Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. EMBO J (2003) 2.30
Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Arthritis Rheum (2006) 2.19
PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development (2002) 2.19
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization. J Clin Invest (2009) 2.18
miR-125b inhibits osteoblastic differentiation by down-regulation of cell proliferation. Biochem Biophys Res Commun (2008) 2.16
Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice. J Clin Invest (2004) 2.16
The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum (2004) 2.08
Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination. J Neurosci (2004) 2.04
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Genes Dev (2004) 2.00
Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva. J Biol Chem (2008) 1.88
A "super-aged" society and the "locomotive syndrome". J Orthop Sci (2008) 1.87
Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system. Immunol Rev (2005) 1.81
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells. J Cereb Blood Flow Metab (2006) 1.75
Prognostic factors for patients with spinal metastases from lung cancer. Spine (Phila Pa 1976) (2006) 1.72
Suppressive function of androgen receptor in bone resorption. Proc Natl Acad Sci U S A (2003) 1.72
Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res (2002) 1.69
SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. J Cell Biol (2006) 1.67
A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese. Hum Mol Genet (2005) 1.67
Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. J Biol Chem (2004) 1.65
Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. J Biol Chem (2003) 1.59
Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency. Dev Dyn (2007) 1.56
Akt1 in osteoblasts and osteoclasts controls bone remodeling. PLoS One (2007) 1.56
Statistics for orthopedic surgery 2006-2007: data from the Japanese Diagnosis Procedure Combination database. J Orthop Sci (2010) 1.55
Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity. Dev Cell (2008) 1.54
Venous sampling for fibroblast growth factor-23 confirms preoperative diagnosis of tumor-induced osteomalacia. J Clin Endocrinol Metab (2004) 1.54
A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia. Haematologica (2005) 1.53
Prediction of strength and strain of the proximal femur by a CT-based finite element method. J Biomech (2006) 1.53
3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells. Biomaterials (2009) 1.50
Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. J Biol Chem (2006) 1.49
Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice. Arthritis Rheum (2012) 1.49
Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair. J Bone Joint Surg Am (2011) 1.48
Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo. Proc Natl Acad Sci U S A (2004) 1.46
miR-210 promotes osteoblastic differentiation through inhibition of AcvR1b. FEBS Lett (2009) 1.46
Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways. J Cell Biochem (2006) 1.46
Dnm3os, a non-coding RNA, is required for normal growth and skeletal development in mice. Dev Dyn (2008) 1.45
Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. J Biol Chem (2006) 1.45
Growth factor treatment and genetic manipulation stimulate neurogenesis and oligodendrogenesis by endogenous neural progenitors in the injured adult spinal cord. J Neurosci (2006) 1.43
Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP). J Bone Miner Metab (2008) 1.41
Cohort profile: research on Osteoarthritis/Osteoporosis Against Disability study. Int J Epidemiol (2009) 1.39
Cross-talk between Wnt and bone morphogenetic protein 2 (BMP-2) signaling in differentiation pathway of C2C12 myoblasts. J Biol Chem (2005) 1.39
C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes. Hum Mol Genet (2011) 1.37