Published in FASEB J on September 01, 2005
Not(ch) just development: Notch signalling in the adult brain. Nat Rev Neurosci (2011) 1.69
Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J (2006) 1.51
Notch1 hallmarks fibrillary depositions in sporadic Alzheimer's disease. Acta Neuropathol Commun (2016) 1.38
Notch: from neural development to neurological disorders. J Neurochem (2008) 1.31
Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine. Proc Natl Acad Sci U S A (2007) 1.08
Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins. J Biol Chem (2012) 1.07
Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities. Neural Plast (2012) 1.00
Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664. J Neurochem (2007) 1.00
Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Aβ metabolism. Biochim Biophys Acta (2011) 0.93
Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories. Neurobiol Aging (2008) 0.92
Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2. Orphanet J Rare Dis (2013) 0.86
APP Receptor? To Be or Not To Be. Trends Pharmacol Sci (2016) 0.85
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome. J Biol Chem (2013) 0.85
A role for FE65 in controlling GnRH-1 neurogenesis. J Neurosci (2011) 0.84
Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos. PLoS One (2013) 0.81
Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation. Eur J Pharmacol (2010) 0.79
A novel function of the Fe65 neuronal adaptor in estrogen receptor action in breast cancer cells. J Biol Chem (2014) 0.78
Pharmacological approaches to intervention in hypomyelinating and demyelinating white matter pathology. Neuropharmacology (2015) 0.78
An entorhinal cortex sulcal pattern is associated with Alzheimer's disease. Hum Brain Mapp (2009) 0.78
Increased expression of Notch1 in temporal lobe epilepsy: animal models and clinical evidence. Neural Regen Res (2014) 0.76
Notch signaling pathway is activated in motoneurons of spinal muscular atrophy. Int J Mol Sci (2013) 0.76
Notch Intracellular Domain (NICD) Suppresses Long-Term Memory Formation in Adult Drosophila Flies. Cell Mol Neurobiol (2015) 0.76
RNAi for contactin 2 inhibits proliferation of U87-glioma stem cells by downregulating AICD, EGFR, and HES1. Onco Targets Ther (2017) 0.75
APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins. Front Mol Neurosci (2017) 0.75
Evaluation of APP695 Transgenic Mice Bone Marrow Mesenchymal Stem Cells Neural Differentiation for Transplantation. Biomed Res Int (2015) 0.75
Ganglioside-Dependent Neural Stem Cell Proliferation in Alzheimer's Disease Model Mice. ASN Neuro (2015) 0.75
hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay. Mol Cell Biol (2006) 2.69
Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum. Hum Mol Genet (2005) 2.36
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. JAMA (2008) 2.07
Elimination of inhibitory synapses is a major component of adult ocular dominance plasticity. Neuron (2012) 1.97
Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease. J Neurosci (2005) 1.68
The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain. Brain (2011) 1.64
Enteric GFAP expression and phosphorylation in Parkinson's disease. J Neurochem (2014) 1.51
Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway. Proc Natl Acad Sci U S A (2005) 1.45
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation. J Cell Biol (2002) 1.42
Adult human subventricular, subgranular, and subpial zones contain astrocytes with a specialized intermediate filament cytoskeleton. Glia (2005) 1.29
Defective glial maturation in vanishing white matter disease. J Neuropathol Exp Neurol (2011) 1.25
Longterm quiescent cells in the aged human subventricular neurogenic system specifically express GFAP-delta. Aging Cell (2010) 1.22
Postsynaptic TrkB signaling has distinct roles in spine maintenance in adult visual cortex and hippocampus. Proc Natl Acad Sci U S A (2006) 1.20
GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease. PLoS One (2012) 1.18
Screening mouse vision with intrinsic signal optical imaging. Eur J Neurosci (2007) 1.18
Argyrophilic grain disease. Brain (2008) 1.13
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice. Neurobiol Aging (2013) 1.12
Glial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-delta, but with consequences for filament organization and alphaB-crystallin association. Mol Biol Cell (2008) 1.12
Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease. J Cell Sci (2007) 1.11
Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases. Hum Mol Genet (2004) 1.10
Dynamic changes in oxytocin receptor expression and activation at parturition in the rat brain. Endocrinology (2007) 1.09
Developmental lineage of cell types in cortical dysplasia with balloon cells. Brain (2007) 1.07
Ubiquitin-conjugating enzyme E2-25K increases aggregate formation and cell death in polyglutamine diseases. Mol Cell Neurosci (2006) 1.06
Cognition enhancers between treating and doping the mind. Pharmacol Res (2008) 1.05
Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model. Glia (2012) 1.04
Disease-specific accumulation of mutant ubiquitin as a marker for proteasomal dysfunction in the brain. FASEB J (2003) 1.04
Diminished aromatase immunoreactivity in the hypothalamus, but not in the basal forebrain nuclei in Alzheimer's disease. Neurobiol Aging (2005) 1.02
Notch1 signaling in pyramidal neurons regulates synaptic connectivity and experience-dependent modifications of acuity in the visual cortex. J Neurosci (2008) 1.01
High interleukin-10 production is associated with low antibody response to influenza vaccination in the elderly. J Leukoc Biol (2006) 1.01
p53 at the crossroads between cancer and neurodegeneration. Free Radic Biol Med (2012) 1.00
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet (2012) 1.00
The synaptic proteome during development and plasticity of the mouse visual cortex. Mol Cell Proteomics (2011) 0.99
Reactive glia show increased immunoproteasome activity in Alzheimer's disease. Brain (2013) 0.99
Selective impairment of p53-mediated cell death in fibroblasts from sporadic Alzheimer's disease patients. J Cell Sci (2002) 0.98
GFAPdelta in radial glia and subventricular zone progenitors in the developing human cortex. Development (2010) 0.98
Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and/or transcriptional role--relevance for Alzheimer pathology. J Neurochem (2010) 0.98
Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease. Neurobiol Aging (2013) 0.97
Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue. J Neuropathol Exp Neurol (2013) 0.97
Identification of regeneration-associated genes after central and peripheral nerve injury in the adult rat. BMC Neurosci (2003) 0.96
The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B+1. Trends Mol Med (2005) 0.95
Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein. Eur J Biochem (2004) 0.95
Intermediate filament transcription in astrocytes is repressed by proteasome inhibition. FASEB J (2009) 0.95
Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease. Regen Med (2007) 0.95
In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem (2004) 0.94
Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol (2009) 0.94
Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin. Neurobiol Aging (2008) 0.94
The role of GABAergic inhibition in ocular dominance plasticity. Neural Plast (2011) 0.93
Contrast gain control and cortical TrkB signaling shape visual acuity. Nat Neurosci (2010) 0.92
Alzheimer's associated variant ubiquitin causes inhibition of the 26S proteasome and chaperone expression. J Neurochem (2003) 0.92
Unfolded p53: a potential biomarker for Alzheimer's disease. J Alzheimers Dis (2007) 0.91
Capillary electrophoresis studies on the aggregation process of beta-amyloid 1-42 and 1-40 peptides. Electrophoresis (2004) 0.91
Structural plasticity in the developing visual system. Prog Brain Res (2005) 0.90
nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing. J Alzheimers Dis (2009) 0.90
Identification of a mutant-like conformation of p53 in fibroblasts from sporadic Alzheimer's disease patients. Neurobiol Aging (2005) 0.90
Migrating neuroblasts in the adult human brain: a stream reduced to a trickle. Cell Res (2011) 0.89
Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome. Brain (2013) 0.89
Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53. Cancer Immunol Immunother (2009) 0.89
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? Aging (Albany NY) (2010) 0.89
CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity. Electrophoresis (2009) 0.88
Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819). J Med Chem (2006) 0.88
Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease. Acta Neuropathol Commun (2014) 0.87
Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3). FEBS Lett (2011) 0.87
In vivo dehydroepiandrosterone restores age-associated defects in the protein kinase C signal transduction pathway and related functional responses. J Immunol (2002) 0.86
beta-Amyloid precursor protein metabolism: focus on the functions and degradation of its intracellular domain. Pharmacol Res (2010) 0.86
Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside? J Pain Res (2013) 0.86
A star is born: new insights into the mechanism of astrogenesis. Cell Mol Life Sci (2013) 0.85
The neuronal ubiquitin-proteasome system: murine models and their neurological phenotype. Prog Neurobiol (2008) 0.85
Fibroblast glutamate transport in aging and in AD: correlations with disease severity. Neurobiol Aging (2005) 0.85
Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease. PLoS One (2012) 0.85
Functional mapping of the promoter region of the GNB2L1 human gene coding for RACK1 scaffold protein. Gene (2008) 0.84
Conformational diseases: an umbrella for various neurological disorders with an impaired ubiquitin-proteasome system. Neurobiol Aging (2005) 0.84
Over-expression of amyloid precursor protein in HEK cells alters p53 conformational state and protects against doxorubicin. J Neurochem (2007) 0.83
GFAPδ expression in glia of the developmental and adolescent mouse brain. PLoS One (2012) 0.83
Conformationally altered p53: a putative peripheral marker for Alzheimer's disease. Neurodegener Dis (2008) 0.83
Acute beta-amyloid administration disrupts the cholinergic control of dopamine release in the nucleus accumbens. Neuropsychopharmacology (2007) 0.83
Alzheimer-associated APP+1 transgenic mice: frameshift beta-amyloid precursor protein is secreted in cerebrospinal fluid without inducing neuropathology. Neurobiol Aging (2005) 0.83
Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survival. PLoS One (2010) 0.83
Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis. Parkinsons Dis (2012) 0.83
Presenilin mouse and zebrafish models for dementia: focus on neurogenesis. Prog Neurobiol (2010) 0.83
Synaptotagmin-2 is a reliable marker for parvalbumin positive inhibitory boutons in the mouse visual cortex. PLoS One (2012) 0.82
Translational research in genomics of Alzheimer's disease: a review of current practice and future perspectives. J Alzheimers Dis (2010) 0.82
Isolation of neural progenitor cells from the human adult subventricular zone based on expression of the cell surface marker CD271. Stem Cells Transl Med (2014) 0.82
Low levels of mutant ubiquitin are degraded by the proteasome in vivo. J Neurosci Res (2010) 0.82