Published in Nat Rev Neurosci on September 01, 2005
Reprogramming adult Schwann cells to stem cell-like cells by leprosy bacilli promotes dissemination of infection. Cell (2013) 3.55
Myelination and support of axonal integrity by glia. Nature (2010) 3.54
A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science (2009) 2.77
Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harb Perspect Biol (2011) 2.73
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. Neuron (2012) 2.45
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system. Neuron (2008) 2.27
c-Jun is a negative regulator of myelination. J Cell Biol (2008) 2.27
Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med (2012) 2.24
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
The molecular machinery of myelin gene transcription in Schwann cells. Glia (2008) 1.91
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell (2008) 1.86
Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3. J Neurosci (2009) 1.84
Gpr126 is essential for peripheral nerve development and myelination in mammals. Development (2011) 1.77
Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination. J Cell Biol (2007) 1.77
Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation. Science (2009) 1.76
A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination. Nat Neurosci (2007) 1.72
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol (2007) 1.69
The Yin and Yang of YY1 in the nervous system. J Neurochem (2008) 1.68
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci (2011) 1.67
How does the Schwann cell lineage form tumors in NF1? Glia (2008) 1.63
The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein. J Neurosci (2008) 1.60
Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H. Am J Hum Genet (2007) 1.58
Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma. Cancer Cell (2014) 1.57
Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue. Cell (2014) 1.56
Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system. J Cell Biol (2008) 1.54
The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells. Cancer Cell (2008) 1.54
Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4. Am J Hum Genet (2007) 1.50
Nrg1/ErbB signaling networks in Schwann cell development and myelination. Semin Cell Dev Biol (2010) 1.49
Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol (2010) 1.48
A role for Schwann cell-derived neuregulin-1 in remyelination. Nat Neurosci (2012) 1.47
Specific functions for ERK/MAPK signaling during PNS development. Neuron (2011) 1.45
FAK is required for axonal sorting by Schwann cells. J Cell Biol (2007) 1.43
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene. EMBO Mol Med (2009) 1.41
Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus. PLoS One (2009) 1.40
Arrest of myelination and reduced axon growth when Schwann cells lack mTOR. J Neurosci (2012) 1.39
Sox2 and Mitf cross-regulatory interactions consolidate progenitor and melanocyte lineages in the cranial neural crest. Development (2012) 1.37
Convergent genesis of an adult neural crest-like dermal stem cell from distinct developmental origins. Stem Cells (2010) 1.36
Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer. Dev Biol (2007) 1.35
Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1. J Neurosci (2008) 1.30
Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. Proc Natl Acad Sci U S A (2011) 1.29
The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function. Elife (2014) 1.28
Schwann cells: activated peripheral glia and their role in neuropathic pain. Brain Behav Immun (2007) 1.27
The repair Schwann cell and its function in regenerating nerves. J Physiol (2016) 1.26
Connecting the ear to the brain: Molecular mechanisms of auditory circuit assembly. Prog Neurobiol (2011) 1.23
Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation. J Neurosci (2013) 1.22
Glutamatergic neuronal differentiation of mouse embryonic stem cells after transient expression of neurogenin 1 and treatment with BDNF and GDNF: in vitro and in vivo studies. J Neurosci (2008) 1.20
The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Proc Natl Acad Sci U S A (2009) 1.19
MicroRNA-deficient Schwann cells display congenital hypomyelination. J Neurosci (2010) 1.19
The molecular and biophysical characterization of the human blood-nerve barrier: current concepts. J Vasc Res (2013) 1.19
The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration. PLoS One (2012) 1.18
Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination. Nat Neurosci (2010) 1.16
Sustained activation of ERK1/2 MAPK in oligodendrocytes and schwann cells enhances myelin growth and stimulates oligodendrocyte progenitor expansion. J Neurosci (2013) 1.16
Nodes of Ranvier act as barriers to restrict invasion of flanking paranodal domains in myelinated axons. Neuron (2011) 1.16
Schwann Cells: Development and Role in Nerve Repair. Cold Spring Harb Perspect Biol (2015) 1.16
Reinnervation of the tibialis anterior following sciatic nerve crush injury: a confocal microscopic study in transgenic mice. Exp Neurol (2007) 1.15
Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential. Cell Stem Cell (2008) 1.15
Myosin II has distinct functions in PNS and CNS myelin sheath formation. J Cell Biol (2008) 1.14
A double-transgenic mouse used to track migrating Schwann cells and regenerating axons following engraftment of injured nerves. Exp Neurol (2007) 1.14
Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation. J Biol Chem (2008) 1.13
The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211. Neuron (2015) 1.13
Gliopathic pain: when satellite glial cells go bad. Neuroscientist (2009) 1.12
N-WASP is required for membrane wrapping and myelination by Schwann cells. J Cell Biol (2011) 1.12
Analysis of Gpr126 function defines distinct mechanisms controlling the initiation and maturation of myelin. Development (2013) 1.11
MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway. Glia (2009) 1.09
MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. Am J Pathol (2009) 1.08
Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. PLoS One (2010) 1.07
Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling. J Neurosci (2010) 1.06
The function of RhoGTPases in axon ensheathment and myelination. Glia (2008) 1.06
Organization and maintenance of molecular domains in myelinated axons. J Neurosci Res (2013) 1.06
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Res (2011) 1.05
Modularity map of the network of human cell differentiation. Proc Natl Acad Sci U S A (2010) 1.05
Human neural crest stem cells derived from human ESCs and induced pluripotent stem cells: induction, maintenance, and differentiation into functional schwann cells. Stem Cells Transl Med (2012) 1.05
Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice. Brain (2012) 1.05
Tracing the stemness of porcine skin-derived progenitors (pSKP) back to specific marker gene expression. Cloning Stem Cells (2009) 1.04
The role of neuregulin-1 in the response to nerve injury. Future Neurol (2011) 1.03
Direct genesis of functional rodent and human schwann cells from skin mesenchymal precursors. Stem Cell Reports (2014) 1.02
Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging. Aging Cell (2009) 1.02
Signals regulating myelination in peripheral nerves and the Schwann cell response to injury. Curr Opin Neurobiol (2013) 1.00
Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance. J Neurosci (2009) 1.00
Remyelination reporter reveals prolonged refinement of spontaneously regenerated myelin. Proc Natl Acad Sci U S A (2013) 1.00
The analgesic effect on neuropathic pain of retrogradely transported botulinum neurotoxin A involves Schwann cells and astrocytes. PLoS One (2012) 1.00
Erbin is required for myelination in regenerated axons after injury. J Neurosci (2012) 0.99
Schwann cell spectrins modulate peripheral nerve myelination. Proc Natl Acad Sci U S A (2011) 0.99
Profile of microRNAs following rat sciatic nerve injury by deep sequencing: implication for mechanisms of nerve regeneration. PLoS One (2011) 0.99
Neuronal Neuregulin 1 type III directs Schwann cell migration. Development (2011) 0.99
Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding. J Neurosci (2011) 0.99
The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury. J Neurosci (2011) 0.98
Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation. Cancer Res (2011) 0.98
Developmental regulation of microRNA expression in Schwann cells. Mol Cell Biol (2011) 0.98
Non-antagonistic relationship between mitogenic factors and cAMP in adult Schwann cell re-differentiation. Glia (2009) 0.98
Spatial constraints dictate glial territories at murine neuromuscular junctions. J Cell Biol (2011) 0.97
Enteric glia express proteolipid protein 1 and are a transcriptionally unique population of glia in the mammalian nervous system. Glia (2015) 0.97
Laminin is required for Schwann cell morphogenesis. J Cell Sci (2009) 0.96
Differential gene expression in motor and sensory Schwann cells in the rat femoral nerve. J Neurosci Res (2011) 0.95
New insights on Schwann cell development. Glia (2015) 0.95
MMP-28 as a regulator of myelination. BMC Neurosci (2008) 0.95
S-adenosylmethionine levels regulate the schwann cell DNA methylome. Neuron (2014) 0.95
Unwrapping myelination by microRNAs. Neuroscientist (2011) 0.94
Defective adult oligodendrocyte and Schwann cell development, pigment pattern, and craniofacial morphology in puma mutant zebrafish having an alpha tubulin mutation. Dev Biol (2010) 0.94
Rac1 controls Schwann cell myelination through cAMP and NF2/merlin. J Neurosci (2012) 0.94
Negative regulation of myelination: relevance for development, injury, and demyelinating disease. Glia (2008) 2.72
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration. Neuron (2012) 2.45
c-Jun is a negative regulator of myelination. J Cell Biol (2008) 2.27
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity. Nat Neurosci (2009) 1.93
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF. J Neurosci (2002) 1.88
Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death. J Cell Biol (2004) 1.60
c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling. J Cell Biol (2012) 1.38
p38 MAPK activation promotes denervated Schwann cell phenotype and functions as a negative regulator of Schwann cell differentiation and myelination. J Neurosci (2012) 1.20
Glial cells. Int J Biochem Cell Biol (2004) 1.16
Gene profiling and bioinformatic analysis of Schwann cell embryonic development and myelination. Glia (2006) 1.09
Role of N-cadherin in Schwann cell precursors of growing nerves. Glia (2006) 1.08
Mouse schwann cells need both NRG1 and cyclic AMP to myelinate. Glia (2011) 1.08
TGFbeta type II receptor signaling controls Schwann cell death and proliferation in developing nerves. J Neurosci (2006) 1.00
c-Jun expression in human neuropathies: a pilot study. J Peripher Nerv Syst (2011) 1.00
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog. J Neurosci (2006) 0.98
Regulation of the myelin gene periaxin provides evidence for Krox-20-independent myelin-related signalling in Schwann cells. Mol Cell Neurosci (2003) 0.98
A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes. Dev Biol (2006) 0.93
Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system. J Biol Chem (2004) 0.90
beta-Neuregulin and autocrine mediated survival of Schwann cells requires activity of Ets family transcription factors. Mol Cell Neurosci (2002) 0.89
Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trap. Neuron Glia Biol (2006) 0.88
Regulation of Schwann cell differentiation and proliferation by the Pax-3 transcription factor. Glia (2012) 0.86
Control of Schwann cell myelination. F1000 Biol Rep (2010) 0.86
The trunk neural crest and its early glial derivatives: a study of survival responses, developmental schedules and autocrine mechanisms. Mol Cell Neurosci (2004) 0.86
A double point mutation in the DNA-binding region of Egr2 switches its function from inhibition to induction of proliferation: A potential contribution to the development of congenital hypomyelinating neuropathy. Neurobiol Dis (2006) 0.86
Desert hedgehog-patched 2 expression in peripheral nerves during Wallerian degeneration and regeneration. J Neurobiol (2006) 0.82
The RNA-binding protein human antigen R controls global changes in gene expression during Schwann cell development. J Neurosci (2012) 0.80
Calcineurin-nuclear factor of activated T cells regulation of Krox-20 expression in Schwann cells requires elevation of intracellular cyclic AMP. J Neurosci Res (2012) 0.79
Introduction. Schwann cell biology. Glia (2008) 0.79