A twin study of anxiety-related behaviours in pre-school children.

Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Res Hum Genet (2012) 3.00

The GABAergic deficit hypothesis of major depressive disorder. Mol Psychiatry (2010) 1.80

The direction of longitudinal associations between sleep problems and depression symptoms: a study of twins aged 8 and 10 years. Sleep (2009) 1.55

gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression. Biol Psychiatry (2010) 1.39

Genetic influences on behavioral inhibition and anxiety in juvenile rhesus macaques. Genes Brain Behav (2007) 1.35

First genome-wide association study on anxiety-related behaviours in childhood. PLoS One (2013) 1.19

Diagnostic specificity and nonspecificity in the dimensions of preschool psychopathology. J Child Psychol Psychiatry (2007) 1.15

The etiology of behavioral problems and competencies in very young twins. J Abnorm Psychol (2008) 1.06

Genetic influences on anxiety in children: what we've learned and where we're heading. Clin Child Fam Psychol Rev (2007) 1.00

Elucidating risk mechanisms of gene-environment interactions on pediatric anxiety: integrating findings from neuroscience. Eur Arch Psychiatry Clin Neurosci (2008) 1.00

An ecological risk model for early childhood anxiety: the importance of early child symptoms and temperament. J Abnorm Child Psychol (2011) 1.00

A longitudinal twin study of fears from middle childhood to early adulthood: evidence for a developmentally dynamic genome. Arch Gen Psychiatry (2008) 0.99

Genetics of early-onset obsessive-compulsive disorder. Eur Child Adolesc Psychiatry (2010) 0.97

The genetics of obsessive-compulsive disorder: a review. Dialogues Clin Neurosci (2010) 0.95

Interpersonal stress regulation and the development of anxiety disorders: an attachment-based developmental framework. Front Behav Neurosci (2011) 0.94

Family factors in the development and management of anxiety disorders. Clin Child Fam Psychol Rev (2012) 0.94

Individual differences in cognition, affect, and performance: behavioral, neuroimaging, and molecular genetic approaches. Neuroimage (2011) 0.94

Maternal control behavior and locus of control: examining mechanisms in the relation between maternal anxiety disorders and anxiety symptomatology in children. J Abnorm Child Psychol (2010) 0.91

Early temperamental and family predictors of shyness and anxiety. Dev Psychol (2010) 0.91

The structure of psychopathology in a community sample of preschoolers. J Abnorm Child Psychol (2011) 0.90

In the face of uncertainty: a twin study of ambiguous information, anxiety and depression in children. J Abnorm Child Psychol (2007) 0.89

Structural and functional bases of inhibited temperament. Soc Cogn Affect Neurosci (2014) 0.89

Obsessive-compulsive disorder in children and adolescents. Arch Dis Child (2014) 0.88

A genetically informed study of the longitudinal relation between irritability and anxious/depressed symptoms. J Am Acad Child Adolesc Psychiatry (2015) 0.88

Patterns of anxiety symptoms in toddlers and preschool-age children: evidence of early differentiation. J Anxiety Disord (2011) 0.88

Internalizing trajectories in young boys and girls: the whole is not a simple sum of its parts. J Abnorm Child Psychol (2010) 0.87

Stable genetic influence on anxiety-related behaviours across middle childhood. J Abnorm Child Psychol (2012) 0.87

The Association Between Infants' Attention Control and Social Inhibition is Moderated by Genetic and Environmental Risk for Anxiety. Infancy (2011) 0.87

Amygdala-cingulate intrinsic connectivity is associated with degree of social inhibition. Biol Psychol (2014) 0.86

Child and adolescent psychiatric genetics. Eur Child Adolesc Psychiatry (2010) 0.86

Disentangling the associations between autistic-like and internalizing traits: a community based twin study. J Abnorm Child Psychol (2012) 0.86

Intergenerational transmission of risk for social inhibition: the interplay between parental responsiveness and genetic influences. Dev Psychopathol (2013) 0.85

Social and non-social behavioral inhibition in preschool-age children: differential associations with parent-reports of temperament and anxiety. Child Psychiatry Hum Dev (2011) 0.85

The magnitude of genetic and environmental influences on parental and observational measures of behavioral inhibition and shyness in toddlerhood. Behav Genet (2012) 0.83

Preventive intervention for anxious preschoolers and their parents: strengthening early emotional development. Child Psychiatry Hum Dev (2012) 0.83

Internalizing disorders in early childhood: a review of depressive and anxiety disorders. Child Adolesc Psychiatr Clin N Am (2009) 0.82

Treatment of anxiety and depression in the preschool period. J Am Acad Child Adolesc Psychiatry (2013) 0.82

Bringing a developmental perspective to anxiety genetics. Dev Psychopathol (2012) 0.82

A multivariate genetic analysis of specific phobia, separation anxiety and social phobia in early childhood. J Abnorm Child Psychol (2008) 0.81

Alternative factor models and heritability of the Short Leyton Obsessional Inventory-Children's Version. J Abnorm Child Psychol (2010) 0.81

Genetics of obsessive-compulsive disorder and related disorders. Psychiatr Clin North Am (2014) 0.79

The genetics of anxiety-related negative valence system traits. Am J Med Genet B Neuropsychiatr Genet (2016) 0.79

Genetic and environmental influences on obsessive-compulsive behaviour across development: a longitudinal twin study. Psychol Med (2014) 0.78

Transactions between child social wariness and observed structured parenting: evidence from a prospective adoption study. Child Dev (2013) 0.78

Parental perfectionism and overcontrol: examining mechanisms in the development of child anxiety. J Abnorm Child Psychol (2015) 0.78

Behavioral inhibition in childhood predicts smaller hippocampal volume in adolescent offspring of parents with panic disorder. Transl Psychiatry (2015) 0.78

Investigating the genetic and environmental bases of biases in threat recognition and avoidance in children with anxiety problems. Biol Mood Anxiety Disord (2012) 0.78

Stressful Life Events and Child Anxiety: Examining Parent and Child Mediators. Child Psychiatry Hum Dev (2016) 0.77

Self-Conscious Shyness: Growth during Toddlerhood, Strong Role of Genetics, and No Prediction from Fearful Shyness. Infancy (2015) 0.77

Finding gene-environment interactions for phobias. Eur Arch Psychiatry Clin Neurosci (2008) 0.77

Finding gene-environment interactions for generalised anxiety disorder. Eur Arch Psychiatry Clin Neurosci (2008) 0.77

Birth and adoptive parent anxiety symptoms moderate the link between infant attention control and internalizing problems in toddlerhood. Dev Psychopathol (2014) 0.76

Perceived family impact of preschool anxiety disorders. J Am Acad Child Adolesc Psychiatry (2014) 0.76

Genome-wide linkage analysis of obsessive-compulsive disorder implicates chromosome 1p36. Biol Psychiatry (2012) 0.75

Analyzing pathways from childhood maltreatment to internalizing symptoms and disorders in children and adolescents (AMIS): a study protocol. BMC Psychiatry (2015) 0.75

Depression and Anxiety in Preschoolers: A Review of the Past 7 Years. Child Adolesc Psychiatr Clin N Am (2017) 0.75

Shared genetic and environmental influences on early temperament and preschool psychiatric disorders in Hispanic twins. Twin Res Hum Genet (2015) 0.75

Latent structure of negative valence measures in childhood. Depress Anxiety (2017) 0.75

Anxiety disorder symptoms in Chinese preschool children. Child Psychiatry Hum Dev (2015) 0.75

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48

Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56

The genetic and environmental origins of learning abilities and disabilities in the early school years. Monogr Soc Res Child Dev (2007) 5.54

The staufen/pumilio pathway is involved in Drosophila long-term memory. Curr Biol (2003) 4.82

Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment. Am J Clin Nutr (2008) 4.79

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42

Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Res (2002) 4.32

A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci U S A (2006) 4.25

Twins' Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence. Twin Res Hum Genet (2007) 4.19

Paternal depression in the postnatal period and child development: a prospective population study. Lancet (2005) 3.89

Time to give up on a single explanation for autism. Nat Neurosci (2006) 3.87

Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab (2008) 3.80

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet (2010) 3.34

Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet (2010) 3.17

The course of anxiety and depression through pregnancy and the postpartum in a community sample. J Affect Disord (2004) 3.16

Genetic heterogeneity between the three components of the autism spectrum: a twin study. J Am Acad Child Adolesc Psychiatry (2006) 3.16

Twins Early Development Study (TEDS): a genetically sensitive investigation of cognitive and behavioral development from childhood to young adulthood. Twin Res Hum Genet (2012) 3.00

Genetic influences on early word recognition abilities and disabilities: a study of 7-year-old twins. J Child Psychol Psychiatry (2005) 2.85

Generalist genes: implications for the cognitive sciences. Trends Cogn Sci (2006) 2.71

Evidence for substantial genetic risk for psychopathy in 7-year-olds. J Child Psychol Psychiatry (2005) 2.64

Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. Immunity (2012) 2.58

Sleep problems in childhood: a longitudinal study of developmental change and association with behavioral problems. J Am Acad Child Adolesc Psychiatry (2002) 2.54

Internet cognitive testing of large samples needed in genetic research. Twin Res Hum Genet (2007) 2.45

Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury. PLoS Biol (2005) 2.36

Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans. Nucleic Acids Res (2006) 2.33

Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis. Clin Child Fam Psychol Rev (2011) 2.29

Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. J Child Psychol Psychiatry (2008) 2.21

Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study. N Engl J Med (2015) 2.19

Genotyping pooled DNA on microarrays: a systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits. Behav Genet (2004) 2.14

The posttraumatic stress disorder diagnosis in preschool- and elementary school-age children exposed to motor vehicle accidents. Am J Psychiatry (2008) 2.10

Parental feeding style and the inter-generational transmission of obesity risk. Obes Res (2002) 2.10

Genetic and environmental influences on adolescent attachment. J Child Psychol Psychiatry (2013) 2.09

Outcomes of early language delay: I. Predicting persistent and transient language difficulties at 3 and 4 years. J Speech Lang Hear Res (2003) 2.01

Early adolescent outcomes for institutionally-deprived and non-deprived adoptees. I: disinhibited attachment. J Child Psychol Psychiatry (2007) 2.01

Are there biological programming effects for psychological development? Findings from a study of Romanian adoptees. Dev Psychol (2004) 2.01

Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Arch Gen Psychiatry (2011) 1.91

SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Hum Mol Genet (2005) 1.91

A three-stage genome-wide association study of general cognitive ability: hunting the small effects. Behav Genet (2010) 1.85

No genetic influence for childhood behavior problems from DNA analysis. J Am Acad Child Adolesc Psychiatry (2013) 1.79

Increasing heritability of BMI and stronger associations with the FTO gene over childhood. Obesity (Silver Spring) (2008) 1.77

A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samples. Behav Genet (2009) 1.75

Identical genetic influences underpin behavior problems in adolescence and basic traits of personality. J Child Psychol Psychiatry (2013) 1.74

Cognitive-behavioral therapy for PTSD in children and adolescents: a preliminary randomized controlled trial. J Am Acad Child Adolesc Psychiatry (2007) 1.73

Relationships between parental negativity and childhood antisocial behavior over time: a bidirectional effects model in a longitudinal genetically informative design. J Abnorm Child Psychol (2007) 1.71

Aetiology of the relationship between callous-unemotional traits and conduct problems in childhood. Br J Psychiatry Suppl (2007) 1.70

Children's perspectives on their relationships with their nonresident fathers: influences, outcomes and implications. J Child Psychol Psychiatry (2004) 1.68

Genetic and environmental contributions to general cognitive ability through the first 16 years of life. Dev Psychol (2004) 1.68

Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics (2005) 1.68

The ABCs of Math: A Genetic Analysis of Mathematics and Its Links With Reading Ability and General Cognitive Ability. J Educ Psychol (2009) 1.66

Depression in men in the postnatal period and later child psychopathology: a population cohort study. J Am Acad Child Adolesc Psychiatry (2008) 1.63

A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds. J Child Psychol Psychiatry (2005) 1.62

Targeted deletion of HIF-1alpha gene in T cells prevents their inhibition in hypoxic inflamed tissues and improves septic mice survival. PLoS One (2007) 1.61

Genetic, environmental and gender influences on attachment disorder behaviours. Br J Psychiatry (2007) 1.60

Early prevention of antisocial personality: long-term follow-up of two randomized controlled trials comparing indicated and selective approaches. Am J Psychiatry (2014) 1.57

Socioeconomic status (SES) and children's intelligence (IQ): in a UK-representative sample SES moderates the environmental, not genetic, effect on IQ. PLoS One (2012) 1.56

Genetic support for the dual nature of attention deficit hyperactivity disorder: substantial genetic overlap between the inattentive and hyperactive-impulsive components. J Abnorm Child Psychol (2007) 1.55

Normality and impairment following profound early institutional deprivation: a longitudinal follow-up into early adolescence. Dev Psychol (2007) 1.55

Phenotypic and genetic overlap between autistic traits at the extremes of the general population. J Am Acad Child Adolesc Psychiatry (2006) 1.54

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52

Interactions between buprenorphine and antiretrovirals. I. The nonnucleoside reverse-transcriptase inhibitors efavirenz and delavirdine. Clin Infect Dis (2006) 1.52

DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage. Am J Med Genet B Neuropsychiatr Genet (2008) 1.50

Mutual influence of marital conflict and children's behavior problems: shared and nonshared family risks. Child Dev (2005) 1.50

Maternal prenatal anxiety and downregulation of placental 11β-HSD2. Psychoneuroendocrinology (2011) 1.49

The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Dev Sci (2005) 1.47

Treatment of chronic hepatitis C patients with the NS3/4A protease inhibitor danoprevir (ITMN-191/RG7227) leads to robust reductions in viral RNA: a phase 1b multiple ascending dose study. J Hepatol (2011) 1.47

FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo. Proc Natl Acad Sci U S A (2010) 1.46

Genetic evidence for bidirectional effects of early lexical and grammatical development. Child Dev (2003) 1.46

Prosocial behavior from early to middle childhood: genetic and environmental influences on stability and change. Dev Psychol (2006) 1.46

Maternal stress during pregnancy predicts cognitive ability and fearfulness in infancy. J Am Acad Child Adolesc Psychiatry (2007) 1.45

No moderating effect of 5-HTTLPR on associations between antenatal anxiety and infant behavior. J Am Acad Child Adolesc Psychiatry (2013) 1.44

Maternal prenatal cortisol and infant cognitive development: moderation by infant-mother attachment. Biol Psychiatry (2010) 1.43

Nonshared environmental influences on individual differences in early behavioral development: a monozygotic twin differences study. Child Dev (2003) 1.43

Learning abilities and disabilities: generalist genes in early adolescence. Cogn Neuropsychiatry (2009) 1.42

Previous prenatal loss as a predictor of perinatal depression and anxiety. Br J Psychiatry (2011) 1.41

Genetic influences in different aspects of language development: the etiology of language skills in 4.5-year-old twins. Child Dev (2005) 1.41

The etiology of behavior problems in 7-year-old twins: substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. J Abnorm Child Psychol (2005) 1.38

Genetic influences on the stability of attention-deficit/hyperactivity disorder symptoms from early to middle childhood. Biol Psychiatry (2005) 1.37

Genetic and environmental influences in adolescent peer socialization: evidence from two genetically sensitive designs. Child Dev (2004) 1.35

Mathematical ability of 10-year-old boys and girls: genetic and environmental etiology of typical and low performance. J Learn Disabil (2007) 1.34

From learning to read to reading to learn: substantial and stable genetic influence. Child Dev (2007) 1.33

The structure of language abilities at 4 years: a twin study. Dev Psychol (2002) 1.32

Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation. Epigenetics Chromatin (2009) 1.29

Prediction of peer-rated adult hostility from autonomy struggles in adolescent-family interactions. Dev Psychopathol (2002) 1.29

Dramatic increase in heritability of cognitive development from early to middle childhood: an 8-year longitudinal study of 8,700 pairs of twins. Psychol Sci (2009) 1.28

Learning Abilities and Disabilities: Generalist Genes, Specialist Environments. Curr Dir Psychol Sci (2007) 1.28

A longitudinal twin study on the association between ADHD symptoms and reading. J Child Psychol Psychiatry (2011) 1.26

The effects of pre- and postnatal depression in fathers: a natural experiment comparing the effects of exposure to depression on offspring. J Child Psychol Psychiatry (2008) 1.26

Maladaptive cognitive appraisals mediate the evolution of posttraumatic stress reactions: A 6-month follow-up of child and adolescent assault and motor vehicle accident survivors. J Abnorm Psychol (2009) 1.26

DNA evidence for strong genome-wide pleiotropy of cognitive and learning abilities. Behav Genet (2013) 1.26

Etiologies of associations between childhood sleep and behavioral problems in a large twin sample. J Am Acad Child Adolesc Psychiatry (2004) 1.25

The etiology of variation in language skills changes with development: a longitudinal twin study of language from 2 to 12 years. Dev Sci (2012) 1.25

Genetic etiology in cases of recovered and persistent stuttering in an unselected, longitudinal sample of young twins. Am J Speech Lang Pathol (2007) 1.25

Structure of the absent in melanoma 2 (AIM2) pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly. J Biol Chem (2013) 1.24

Person-centered psychopathology of schizophrenia: building on Karl Jaspers' understanding of patient's attitude toward his illness. Schizophr Bull (2013) 1.23

Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies. BMC Genomics (2007) 1.22