Published in Clin Endocrinol (Oxf) on October 01, 2005
Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates | NCT00517062
Fifteen years of GH replacement improves body composition and cardiovascular risk factors. Eur J Endocrinol (2013) 1.11
Growth hormone decreases visceral fat and improves cardiovascular risk markers in women with hypopituitarism: a randomized, placebo-controlled study. J Clin Endocrinol Metab (2008) 1.11
Incidence of diabetes mellitus and evolution of glucose parameters in growth hormone-deficient subjects during growth hormone replacement therapy: a long-term observational study. Diabetes Care (2011) 0.80
Short-term, low-dose GH therapy improves insulin sensitivity without modifying cortisol metabolism and ectopic fat accumulation in adults with GH deficiency. J Clin Endocrinol Metab (2014) 0.77
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet (2007) 19.04
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet (2006) 8.65
Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial. Lancet (2010) 6.50
Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care (2007) 6.38
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes (2004) 4.81
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 4.36
Circulating levels of IGF-1 directly regulate bone growth and density. J Clin Invest (2002) 3.86
A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science (2004) 3.54
Early insulin therapy in very-low-birth-weight infants. N Engl J Med (2008) 3.51
Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. BMJ (2011) 3.36
Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. J Natl Cancer Inst (2002) 3.32
Serum adiponectin predicts all-cause mortality and end stage renal disease in patients with type I diabetes and diabetic nephropathy. Kidney Int (2008) 3.27
Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure. Circulation (2005) 2.81
Poor prognosis of young adults with type 1 diabetes: a longitudinal study. Diabetes Care (2003) 2.75
Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis. J Clin Invest (2009) 2.53
Overnight closed-loop insulin delivery in young people with type 1 diabetes: a free-living, randomized clinical trial. Diabetes Care (2014) 2.53
Obesity and cancer risk: the role of the insulin-IGF axis. Trends Endocrinol Metab (2006) 2.52
Prevalence and determinants of hyperglycemia in very low birth weight infants: cohort analyses of the NIRTURE study. J Pediatr (2010) 2.50
Risk of microalbuminuria and progression to macroalbuminuria in a cohort with childhood onset type 1 diabetes: prospective observational study. BMJ (2008) 2.25
Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis. Pediatr Res (2002) 2.22
Association of weight gain in infancy and early childhood with metabolic risk in young adults. J Clin Endocrinol Metab (2006) 2.15
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study. Lancet (2002) 2.12
The prevalence of stunting, overweight and obesity, and metabolic disease risk in rural South African children. BMC Public Health (2010) 2.08
Childhood obesity and the timing of puberty. Trends Endocrinol Metab (2009) 2.00
Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES). Am J Clin Nutr (2006) 1.99
Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. PLoS Med (2010) 1.88
Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children. J Clin Endocrinol Metab (2006) 1.87
Closed-loop basal insulin delivery over 36 hours in adolescents with type 1 diabetes: randomized clinical trial. Diabetes Care (2012) 1.84
Whey and casein labeled with L-[1-13C]leucine and muscle protein synthesis: effect of resistance exercise and protein ingestion. Am J Physiol Endocrinol Metab (2010) 1.82
Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC. EMBO Mol Med (2009) 1.80
Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes. Diabetes (2011) 1.78
Insulin sensitivity and secretion are related to catch-up growth in small-for-gestational-age infants at age 1 year: results from a prospective cohort. J Clin Endocrinol Metab (2003) 1.70
Low IGF-I and elevated testosterone during puberty in subjects with type 1 diabetes developing microalbuminuria in comparison to normoalbuminuric control subjects: the Oxford Regional Prospective Study. Diabetes Care (2003) 1.68
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes. Diabetes (2007) 1.68
The relationship of disordered eating habits and attitudes to clinical outcomes in young adult females with type 1 diabetes. Diabetes Care (2005) 1.64
Overnight closed-loop insulin delivery with model predictive control: assessment of hypoglycemia and hyperglycemia risk using simulation studies. J Diabetes Sci Technol (2009) 1.63
Variation in the ADIPOQ gene promoter is associated with carotid intima media thickness independent of plasma adiponectin levels in healthy subjects. Eur Heart J (2007) 1.63
Leptin, not adiponectin, predicts hypertension in the Copenhagen City Heart Study. Am J Hypertens (2009) 1.61
Adiponectin and lipoprotein particle size. Diabetes Care (2009) 1.60
Closed-loop insulin delivery during pregnancy complicated by type 1 diabetes. Diabetes Care (2011) 1.57
Safety and efficacy of 24-h closed-loop insulin delivery in well-controlled pregnant women with type 1 diabetes: a randomized crossover case series. Diabetes Care (2011) 1.57
Childhood-onset growth hormone deficiency, cognitive function and brain N-acetylaspartate. Psychoneuroendocrinology (2005) 1.55
A novel dysfunctional growth hormone variant (Ile179Met) exhibits a decreased ability to activate the extracellular signal-regulated kinase pathway. J Clin Endocrinol Metab (2004) 1.55
The metabolic syndrome is frequent in Klinefelter's syndrome and is associated with abdominal obesity and hypogonadism. Diabetes Care (2006) 1.52
Conscious level in children with diabetic ketoacidosis is related to severity of acidosis and not to blood glucose concentration. Pediatr Diabetes (2006) 1.52
Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial. BMJ (2011) 1.50
The potential impact of the fetal genotype on maternal blood pressure during pregnancy. J Hypertens (2014) 1.49
Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung. J Clin Endocrinol Metab (2007) 1.49
Infancy weight gain predicts childhood body fat and age at menarche in girls. J Clin Endocrinol Metab (2009) 1.47
Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes. J Diabetes Sci Technol (2010) 1.47
Parental attitudes towards overnight closed-loop glucose control in children with type 1 diabetes. Diabetes Technol Ther (2010) 1.46
Human growth hormone responses to repeated bouts of sprint exercise with different recovery periods between bouts. J Appl Physiol (1985) (2005) 1.45
The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab (2008) 1.45
Anogenital distance from birth to 2 years: a population study. Environ Health Perspect (2009) 1.44
Osteoprotegerin predicts long-term outcome in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention. Cardiology (2012) 1.44
Hypoglycemia prevalence in prepubertal children with type 1 diabetes on standard insulin regimen: use of continuous glucose monitoring system. Diabetes Care (2003) 1.43
Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index. Pediatrics (2006) 1.43
Endothelial insulin receptor expression in human atherosclerotic plaques: linking micro- and macrovascular disease in diabetes? Atherosclerosis (2012) 1.41
The relationship between microalbuminuria and glomerular filtration rate in young type 1 diabetic subjects: The Oxford Regional Prospective Study. Kidney Int (2005) 1.40
Evaluation of a portable ambulatory prototype for automated overnight closed-loop insulin delivery in young people with type 1 diabetes. Pediatr Diabetes (2012) 1.40
Human growth hormone 1 (GH1) gene expression: complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region. Hum Mutat (2003) 1.39
Serum adiponectin is increased in type 1 diabetic patients with nephropathy. Diabetes Care (2005) 1.35
Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies. Diabetes (2007) 1.35
Validation of a quantitative magnetic resonance method for measuring human body composition. Obesity (Silver Spring) (2008) 1.34
Birth weight, infant growth and insulin resistance. Eur J Endocrinol (2004) 1.34
Insulin-like growth factor I concentrations in infancy predict differential gains in body length and adiposity: the Cambridge Baby Growth Study. Am J Clin Nutr (2009) 1.33
Cardiovascular disease and insulin-like growth factor I. Circulation (2002) 1.30
A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum. Am J Physiol Endocrinol Metab (2003) 1.30
Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5. Mol Endocrinol (2006) 1.29
Randomized cross-over trial of insulin glargine plus lispro or NPH insulin plus regular human insulin in adolescents with type 1 diabetes on intensive insulin regimens. Diabetes Care (2003) 1.27
Lessons from large population studies on timing and tempo of puberty (secular trends and relation to body size): the European trend. Mol Cell Endocrinol (2006) 1.25
Insulin-like growth factor I (IGF-I) replacement therapy increases albumin concentration in liver cirrhosis: results of a pilot randomized controlled clinical trial. J Hepatol (2005) 1.23
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J (2008) 1.23
Earlier mother's age at menarche predicts rapid infancy growth and childhood obesity. PLoS Med (2007) 1.22
Mitochondrial dysfunction in patients with primary congenital insulin resistance. J Clin Invest (2011) 1.19
A single administration of testosterone improves visuospatial ability in young women. Psychoneuroendocrinology (2004) 1.18
Plasma adiponectin in patients with active, early, and chronic rheumatoid arthritis who are steroid- and disease-modifying antirheumatic drug-naive compared with patients with osteoarthritis and controls. J Rheumatol (2009) 1.18
Fasting unmasks a strong inverse association between ghrelin and cortisol in serum: studies in obese and normal-weight subjects. J Clin Endocrinol Metab (2004) 1.17
Evaluating the accuracy and large inaccuracy of two continuous glucose monitoring systems. Diabetes Technol Ther (2012) 1.16
Nutritional status and HIV in rural South African children. BMC Pediatr (2011) 1.15
Ghrelin and its relationship to growth hormones during normal pregnancy. Clin Endocrinol (Oxf) (2005) 1.15
Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans. BMC Genet (2005) 1.14
Effect of estrogen on tendon collagen synthesis, tendon structural characteristics, and biomechanical properties in postmenopausal women. J Appl Physiol (1985) (2008) 1.13
Sex differences for selective forms of spatial memory. Brain Cogn (2004) 1.12
Gender differences of oligomers and total adiponectin during puberty: a cross-sectional study of 859 Danish school children. J Clin Endocrinol Metab (2007) 1.12
Elevated levels of high-molecular-weight adiponectin in type 1 diabetes. J Clin Endocrinol Metab (2008) 1.12
Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers. Diabetes Care (2008) 1.12
The metabolic profile of early Huntington's disease--a combined human and transgenic mouse study. Exp Neurol (2008) 1.11
Automated overnight closed-loop glucose control in young children with type 1 diabetes. Diabetes Technol Ther (2011) 1.11
Fat distribution in non-obese girls with and without precocious pubarche: central adiposity related to insulinaemia and androgenaemia from prepuberty to postmenarche. Clin Endocrinol (Oxf) (2003) 1.11
Glucose and lipid metabolism in small for gestational age infants at 48 hours of age. Pediatrics (2003) 1.11
DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial. FASEB J (2012) 1.11
Metformin treatment to prevent early puberty in girls with precocious pubarche. J Clin Endocrinol Metab (2006) 1.10
Complement abnormalities in acquired lipodystrophy revisited. J Clin Endocrinol Metab (2008) 1.10
Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin. Crit Care (2009) 1.10
Reference intervals for insulin-like growth factor-1 (igf-i) from birth to senescence: results from a multicenter study using a new automated chemiluminescence IGF-I immunoassay conforming to recent international recommendations. J Clin Endocrinol Metab (2014) 1.09