Published in Biochem Biophys Res Commun on November 04, 2005
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The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to L-phenylalanine in acutely isolated intestinal I cells. Am J Physiol Gastrointest Liver Physiol (2011) 1.41
Gastrointestinal chemosensation: chemosensory cells in the alimentary tract. Histochem Cell Biol (2012) 1.11
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Physiological and pathophysiological roles of ATP-sensitive K+ channels. Prog Biophys Mol Biol (2003) 3.09
Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice. J Clin Invest (2002) 2.74
Kir6.2 is required for adaptation to stress. Proc Natl Acad Sci U S A (2002) 2.60
Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP. Proc Natl Acad Sci U S A (2007) 2.59
GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure. Nat Med (2013) 2.31
PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue. Cell Metab (2012) 2.24
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The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs. Science (2009) 1.90
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells. Proc Natl Acad Sci U S A (2005) 1.87
Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis. J Biol Chem (2002) 1.85
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice. Circulation (2003) 1.84
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab (2002) 1.82
KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart. Am J Physiol Heart Circ Physiol (2006) 1.74
Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant. J Physiol (2006) 1.70
LKB1 regulates pancreatic beta cell size, polarity, and function. Cell Metab (2009) 1.70
Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis. J Biol Chem (2003) 1.66
Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1. J Exp Med (2007) 1.64
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet (2002) 1.63
International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev (2005) 1.63
K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nat Neurosci (2005) 1.62
Roles of KATP channels as metabolic sensors in acute metabolic changes. J Mol Cell Cardiol (2005) 1.62
KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation. Nat Clin Pract Cardiovasc Med (2007) 1.56
Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics. Am J Physiol Heart Circ Physiol (2003) 1.56
KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension. Hum Mol Genet (2006) 1.53
ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits. Diabetes (2004) 1.53
Beneficial effects of a low-protein diet on host resistance to Paracoccidioides brasiliensis in mice. Nutrition (2009) 1.44
Embryonic stem cell therapy of heart failure in genetic cardiomyopathy. Stem Cells (2008) 1.39
Exportin-5 orthologues are functionally divergent among species. Nucleic Acids Res (2006) 1.29
Gene knockout of the KCNJ8-encoded Kir6.1 K(ATP) channel imparts fatal susceptibility to endotoxemia. FASEB J (2006) 1.28
ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue. Am J Physiol Endocrinol Metab (2002) 1.25
K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration. Nat Neurosci (2012) 1.24
Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K+ channel, predisposes to catecholamine-induced ventricular dysrhythmia. Diabetes (2004) 1.23
Identification of distinct ligands for the C-type lectin receptors Mincle and Dectin-2 in the pathogenic fungus Malassezia. Cell Host Microbe (2013) 1.17
Rho and anillin-dependent control of mDia2 localization and function in cytokinesis. Mol Biol Cell (2010) 1.17
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility. Diabetes (2005) 1.16
Phylogenetic studies of Nocardia species based on gyrB gene analyses. J Med Microbiol (2009) 1.15
Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice. Diabetes (2004) 1.13
Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects. Diabetes (2006) 1.09
NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins. Nucleic Acids Res (2007) 1.09
β cell dysfunction versus insulin resistance in the pathogenesis of type 2 diabetes in East Asians. Curr Diab Rep (2015) 1.07
Gene targeting approach to clarification of ion channel function: studies of Kir6.x null mice. J Physiol (2003) 1.06
Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion. J Biol Chem (2006) 1.05
Pancreatic β-cells are generated by neogenesis from non-β-cells after birth. Biomed Res (2011) 1.04
Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells. Proc Natl Acad Sci U S A (2004) 1.02
Rim2alpha determines docking and priming states in insulin granule exocytosis. Cell Metab (2010) 1.02
Integration of ATP, cAMP, and Ca2+ signals in insulin granule exocytosis. Diabetes (2004) 1.01
Antidiabetic sulfonylureas and cAMP cooperatively activate Epac2A. Sci Signal (2013) 1.01
Multilocus microsatellite typing for Cryptococcus neoformans var. grubii. Med Mycol (2008) 1.01
Severe hypophosphatemic osteomalacia with Fanconi syndrome, renal tubular acidosis, vitamin D deficiency and primary biliary cirrhosis. Intern Med (2009) 1.00
Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels. J Neurophysiol (2005) 1.00
Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels. Diabetes (2004) 1.00
Direct inhibition of the interaction between alpha-interaction domain and beta-interaction domain of voltage-dependent Ca2+ channels by Gem. J Biol Chem (2004) 0.99
Role of cadherin-mediated cell-cell adhesion in pancreatic exocrine-to-endocrine transdifferentiation. J Biol Chem (2008) 0.99
Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function. J Cell Physiol (2009) 0.99
Pancreatic acinar-to-beta cell transdifferentiation in vitro. Front Biosci (2008) 0.98
Role of osteoglycin in the linkage between muscle and bone. J Biol Chem (2012) 0.98
Characterization of clinical isolates of Gordonia species in Japanese clinical samples during 1998-2008. Mycopathologia (2009) 0.98
The human mitochondrial KATP channel is modulated by calcium and nitric oxide: a patch-clamp approach. Biochim Biophys Acta (2004) 0.97
Prevalence of hepatitis C virus subgenotypes 1a and 1b in Japanese patients: ultra-deep sequencing analysis of HCV NS5B genotype-specific region. PLoS One (2013) 0.97
Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis. Genes Cells (2009) 0.97
Restricted expression of somatostatin receptor 3 to primary cilia in the pancreatic islets and adenohypophysis of mice. Biomed Res (2011) 0.95
Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression. J Biol Chem (2007) 0.93
Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes. Am J Physiol Endocrinol Metab (2006) 0.92
NikA/TcsC histidine kinase is involved in conidiation, hyphal morphology, and responses to osmotic stress and antifungal chemicals in Aspergillus fumigatus. PLoS One (2013) 0.92
Smad7 inhibits differentiation and mineralization of mouse osteoblastic cells. Endocr J (2012) 0.91
Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs. Nucleic Acids Res (2007) 0.91
Parathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathway. J Biol Chem (2011) 0.91
Proteomic profiling of KATP channel-deficient hypertensive heart maps risk for maladaptive cardiomyopathic outcome. Proteomics (2009) 0.91
Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels. Eur J Pharmacol (2004) 0.90
ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling. Am J Physiol Endocrinol Metab (2003) 0.89
FAM5C is a soluble osteoblast differentiation factor linking muscle to bone. Biochem Biophys Res Commun (2012) 0.89
Actin dynamics regulated by the balance of neuronal Wiskott-Aldrich syndrome protein (N-WASP) and cofilin activities determines the biphasic response of glucose-induced insulin secretion. J Biol Chem (2013) 0.89