Published in J Mol Biol on September 08, 2005
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Structural basis for the recognition of blood group trisaccharides by norovirus. J Virol (2007) 3.58
Crystal structure of mitochondrial respiratory membrane protein complex II. Cell (2005) 3.44
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature (2008) 3.06
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor. Proc Natl Acad Sci U S A (2003) 3.02
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BRITTLE CULM1, which encodes a COBRA-like protein, affects the mechanical properties of rice plants. Plant Cell (2003) 2.19
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The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing. Cell (2012) 2.07
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Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin. Arterioscler Thromb Vasc Biol (2009) 1.80
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MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. Proc Natl Acad Sci U S A (2010) 1.73
Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol (2005) 1.73
Structural and regulatory genes required to make the gas dimethyl sulfide in bacteria. Science (2007) 1.72
Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer. Nat Struct Mol Biol (2005) 1.68
A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both A1C and glucose. Diabetes (2009) 1.65
Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core. J Biol Chem (2004) 1.64
Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses. Proc Natl Acad Sci U S A (2012) 1.63
Crystal structure of group II chaperonin in the open state. Structure (2010) 1.62
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proc Natl Acad Sci U S A (2011) 1.59
Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer. Mol Cancer (2011) 1.59
Picornavirus uncoating intermediate captured in atomic detail. Nat Commun (2013) 1.57
3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex. Proc Natl Acad Sci U S A (2004) 1.57
Complex two-gene modulation of lung disease severity in children with cystic fibrosis. J Clin Invest (2008) 1.57
Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis study. Virology (2008) 1.54
Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity. FASEB J (2009) 1.52
Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase. FEBS J (2008) 1.49
Spectral analysis of multiplex Raman probe signatures. ACS Nano (2008) 1.49
Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1. J Mol Biol (2003) 1.47
The multifunctional human p100 protein 'hooks' methylated ligands. Nat Struct Mol Biol (2007) 1.46
Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J Biol Chem (2003) 1.45
Robust and powerful tests for rare variants using Fisher's method to combine evidence of association from two or more complementary tests. Genet Epidemiol (2012) 1.45
F gene recombination between genotype II and VII Newcastle disease virus. Virus Res (2007) 1.42
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J Virol (2007) 1.41
Cyclophilin A interacts with influenza A virus M1 protein and impairs the early stage of the viral replication. Cell Microbiol (2009) 1.40
An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor. J Biol Chem (2006) 1.40
Clinical use of supinator motor branch transfer to the posterior interosseous nerve in C7-T1 brachial plexus palsies. J Neurosurg (2010) 1.40
Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands. Trends Immunol (2002) 1.40
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Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1. Cancer Lett (2009) 1.38
Identification and characterization of catabolic para-nitrophenol 4-monooxygenase and para-benzoquinone reductase from Pseudomonas sp. strain WBC-3. J Bacteriol (2009) 1.37
Locus-specific heritability estimation via the bootstrap in linkage scans for quantitative trait loci. Hum Hered (2006) 1.36
Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center. J Virol (2009) 1.35
Differentiation of bone marrow-derived mesenchymal stem cells from diabetic patients into insulin-producing cells in vitro. Chin Med J (Engl) (2007) 1.35
Multiple variants in vascular endothelial growth factor (VEGFA) are risk factors for time to severe retinopathy in type 1 diabetes: the DCCT/EDIC genetics study. Diabetes (2007) 1.34
Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. EMBO J (2010) 1.33
WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. EMBO J (2013) 1.32
Development of a dual-modal tissue diagnostic system combining time-resolved fluorescence spectroscopy and ultrasonic backscatter microscopy. Rev Sci Instrum (2009) 1.32
Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens. PLoS Pathog (2011) 1.31
Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1). J Mol Biol (2006) 1.30
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Composite organic-inorganic nanoparticles (COINs) with chemically encoded optical signatures. Nano Lett (2005) 1.30
An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction. J Exp Med (2005) 1.29
ENU-induced phenovariance in mice: inferences from 587 mutations. BMC Res Notes (2012) 1.28
A nuclear export signal in the matrix protein of Influenza A virus is required for efficient virus replication. J Virol (2012) 1.28
Imaging and characterizing influenza A virus mRNA transport in living cells. Nucleic Acids Res (2008) 1.26
The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans. Autophagy (2011) 1.26
Split mCherry as a new red bimolecular fluorescence complementation system for visualizing protein-protein interactions in living cells. Biochem Biophys Res Commun (2007) 1.25
A novel method for detection of phosphorylation in single cells by surface enhanced Raman scattering (SERS) using composite organic-inorganic nanoparticles (COINs). PLoS One (2009) 1.24
A flexible genome-wide bootstrap method that accounts for ranking and threshold-selection bias in GWAS interpretation and replication study design. Stat Med (2011) 1.23
Atomic resolution structure of Moloney murine leukemia virus matrix protein and its relationship to other retroviral matrix proteins. Structure (2002) 1.23
Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor. J Biol Chem (2003) 1.23
Crystal structure of cytotoxin protein suilysin from Streptococcus suis. Protein Cell (2010) 1.23
MicroRNAs in adipogenesis and as therapeutic targets for obesity. Expert Opin Ther Targets (2011) 1.22
Structural basis for coronavirus-mediated membrane fusion. Crystal structure of mouse hepatitis virus spike protein fusion core. J Biol Chem (2004) 1.22
Structural insights into SARS coronavirus proteins. Curr Opin Struct Biol (2005) 1.22