Published in Nat Struct Mol Biol on September 25, 2005
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev (2006) 5.59
Regulation of cytoplasmic mRNA decay. Nat Rev Genet (2012) 3.30
Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell (2008) 3.26
The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nat Rev Genet (2008) 3.00
Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2008) 2.74
Organizing principles of mammalian nonsense-mediated mRNA decay. Annu Rev Genet (2013) 2.55
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell (2009) 2.28
Staufen1 regulates diverse classes of mammalian transcripts. EMBO J (2007) 2.18
Upf1 senses 3'UTR length to potentiate mRNA decay. Cell (2010) 2.09
UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps. Mol Cell (2010) 2.04
SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev (2008) 1.97
Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA (2006) 1.83
SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. Genes Dev (2009) 1.82
Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus. Chromosoma (2008) 1.69
Identification of a cytoplasmic complex that adds a cap onto 5'-monophosphate RNA. Mol Cell Biol (2009) 1.67
The human cap-binding complex is functionally connected to the nuclear RNA exosome. Nat Struct Mol Biol (2013) 1.67
Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay. RNA (2008) 1.65
Genome-wide suppression of aberrant mRNA-like noncoding RNAs by NMD in Arabidopsis. Proc Natl Acad Sci U S A (2009) 1.60
Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question. Curr Opin Genet Dev (2011) 1.52
Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails. Mol Cell Biol (2006) 1.50
Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies. J Cell Biol (2007) 1.47
The regulation of mRNA stability in mammalian cells: 2.0. Gene (2012) 1.46
Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis. Mol Cancer Res (2010) 1.44
A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation. Genes Dev (2009) 1.25
Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta. Genes Dev (2009) 1.22
Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana. Nucleic Acids Res (2009) 1.19
Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons. Mol Cell Biol (2007) 1.18
Imaging mRNA movement from transcription sites to translation sites. Semin Cell Dev Biol (2007) 1.17
Crystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1. RNA (2006) 1.11
A post-translational regulatory switch on UPF1 controls targeted mRNA degradation. Genes Dev (2014) 1.09
Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity. Proc Natl Acad Sci U S A (2012) 1.06
Cap-binding protein complex links pre-mRNA capping to transcription elongation and alternative splicing through positive transcription elongation factor b (P-TEFb). J Biol Chem (2011) 1.06
Cap-binding complex (CBC). Biochem J (2014) 1.05
Turnover in the Alps: an mRNA perspective. Workshops on mechanisms and regulation of mRNA turnover. EMBO Rep (2006) 1.03
Nonsense-mediated mRNA decay in humans at a glance. J Cell Sci (2016) 1.01
Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase. EMBO J (2011) 1.00
CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter. Cold Spring Harb Symp Quant Biol (2011) 1.00
Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells. Nat Struct Mol Biol (2013) 1.00
eIF4E-bound mRNPs are substrates for nonsense-mediated mRNA decay in mammalian cells. Nat Struct Mol Biol (2013) 0.99
Gene expression networks: competing mRNA decay pathways in mammalian cells. Biochem Soc Trans (2009) 0.96
The dharma of nonsense-mediated mRNA decay in mammalian cells. Mol Cells (2014) 0.95
NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA. EMBO Rep (2008) 0.95
Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay. EMBO Rep (2006) 0.94
Nonsense-mediated mRNA decay: inter-individual variability and human disease. Neurosci Biobehav Rev (2013) 0.94
A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi. Protein Cell (2011) 0.93
Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay. Mol Cell Biol (2006) 0.93
The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells. RNA (2013) 0.88
The mRNA cap-binding complex stimulates the formation of pre-initiation complex at the promoter via its interaction with Mot1p in vivo. Nucleic Acids Res (2010) 0.87
Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. Nucleic Acids Res (2013) 0.86
RNA decay and RNA silencing in plants: competition or collaboration? Front Plant Sci (2011) 0.85
Binding properties and dynamic localization of an alternative isoform of the cap-binding complex subunit CBP20. Nucleus (2011) 0.84
A novel role for Cet1p mRNA 5'-triphosphatase in promoter proximal accumulation of RNA polymerase II in Saccharomyces cerevisiase. Genetics (2013) 0.78
Making sense of nonsense. Nat Struct Mol Biol (2013) 0.77
Control of mRNA Stability in Fungi by NMD, EJC and CBC Factors Through 3'UTR Introns. Genetics (2015) 0.77
Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination. Wiley Interdiscip Rev RNA (2015) 0.77
Nonsense-mediated mRNA decay immunity can help identify human polycistronic transcripts. PLoS One (2014) 0.75
LIPH expression in skin and hair follicles of normal coat and Rex rabbits. PLoS One (2012) 0.75
Modulation of nonsense mediated decay by rapamycin. Nucleic Acids Res (2016) 0.75
UPF1 helicase promotes TSN-mediated miRNA decay. Genes Dev (2017) 0.75
lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature (2011) 5.42
Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. Genes Dev (2007) 4.97
Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities. Mol Cell (2003) 4.17
Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. Cell (2005) 4.02
Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells. Curr Opin Cell Biol (2005) 3.99
Regulation of cytoplasmic mRNA decay. Nat Rev Genet (2012) 3.30
Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell (2008) 3.26
Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression. Genes Dev (2006) 3.18
The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nat Rev Genet (2008) 3.00
The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling. EMBO J (2002) 2.76
Organizing principles of mammalian nonsense-mediated mRNA decay. Annu Rev Genet (2013) 2.55
Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges. Trends Mol Med (2006) 2.39
Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Mol Cell Biol (2008) 2.25
Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of pre-messenger RNA. Prog Nucleic Acid Res Mol Biol (2004) 2.23
Staufen1 regulates diverse classes of mammalian transcripts. EMBO J (2007) 2.18
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol Cell (2004) 2.09
UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps. Mol Cell (2010) 2.04
SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev (2008) 1.97
A yeast model of FUS/TLS-dependent cytotoxicity. PLoS Biol (2011) 1.95
The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex. Genes Dev (2004) 1.93
Translation of polioviral mRNA is inhibited by cleavage of polypyrimidine tract-binding proteins executed by polioviral 3C(pro). J Virol (2002) 1.77
LIN28A is a suppressor of ER-associated translation in embryonic stem cells. Cell (2012) 1.58
eIF4G is required for the pioneer round of translation in mammalian cells. Nat Struct Mol Biol (2004) 1.54
Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question. Curr Opin Genet Dev (2011) 1.52
Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails. Mol Cell Biol (2006) 1.50
Human proline-rich nuclear receptor coregulatory protein 2 mediates an interaction between mRNA surveillance machinery and decapping complex. Mol Cell (2009) 1.47
Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies. J Cell Biol (2007) 1.47
Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation. Proc Natl Acad Sci U S A (2011) 1.40
Beta -Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon. Proc Natl Acad Sci U S A (2002) 1.33
STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown. Genes Dev (2013) 1.32
Re-capping the message. Trends Biochem Sci (2009) 1.28
Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA. Nat Struct Mol Biol (2007) 1.26
Staufen-mediated mRNA decay. Wiley Interdiscip Rev RNA (2013) 1.26
A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation. Genes Dev (2009) 1.25
Efficiency of the pioneer round of translation affects the cellular site of nonsense-mediated mRNA decay. Mol Cell (2008) 1.22
Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta. Genes Dev (2009) 1.22
Control of myogenesis by rodent SINE-containing lncRNAs. Genes Dev (2013) 1.21
Staufen1-mediated mRNA decay functions in adipogenesis. Mol Cell (2012) 1.20
Temporal and spatial characterization of nonsense-mediated mRNA decay. Genes Dev (2013) 1.18
Nonsense-mediated mRNA decay factors, UPF1 and UPF3, contribute to plant defense. Plant Cell Physiol (2011) 1.17
MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling. Nat Commun (2013) 1.16
Rules that govern UPF1 binding to mRNA 3' UTRs. Proc Natl Acad Sci U S A (2013) 1.13
Rescue of nonsense mutations by amlexanox in human cells. Orphanet J Rare Dis (2012) 1.13
The CD44 alternative v9 exon contains a splicing enhancer responsive to the SR proteins 9G8, ASF/SF2, and SRp20. J Biol Chem (2003) 1.07
Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity. Proc Natl Acad Sci U S A (2012) 1.06
Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast. Proc Natl Acad Sci U S A (2005) 1.05
Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors. PLoS Biol (2007) 1.04
E2 of hepatitis C virus inhibits apoptosis. J Immunol (2005) 1.02
Structural basis of the PNRC2-mediated link between mrna surveillance and decapping. Structure (2012) 1.02
mRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decay. Nat Struct Mol Biol (2013) 1.01
microRNA/Argonaute 2 regulates nonsense-mediated messenger RNA decay. EMBO Rep (2010) 1.00
Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Nat Struct Mol Biol (2013) 1.00
SMG5-PNRC2 is functionally dominant compared with SMG5-SMG7 in mammalian nonsense-mediated mRNA decay. Nucleic Acids Res (2012) 0.98
Cell-surface receptor for complement component C1q (gC1qR) is a key regulator for lamellipodia formation and cancer metastasis. J Biol Chem (2011) 0.97
The dharma of nonsense-mediated mRNA decay in mammalian cells. Mol Cells (2014) 0.95
NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA. EMBO Rep (2008) 0.95
Pioneer round of translation occurs during serum starvation. Biochem Biophys Res Commun (2007) 0.94
Exon junction complex enhances translation of spliced mRNAs at multiple steps. Biochem Biophys Res Commun (2009) 0.93
Ectopic expression of eIF4E-transporter triggers the movement of eIF4E into P-bodies, inhibiting steady-state translation but not the pioneer round of translation. Biochem Biophys Res Commun (2008) 0.93
"Alu"strious long ncRNAs and their role in shortening mRNA half-lives. Cell Cycle (2011) 0.92
Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2. FEBS Lett (2011) 0.91
Biochemical analysis of long non-coding RNA-containing ribonucleoprotein complexes. Methods (2012) 0.91
Translation initiation on mRNAs bound by nuclear cap-binding protein complex CBP80/20 requires interaction between CBP80/20-dependent translation initiation factor and eukaryotic translation initiation factor 3g. J Biol Chem (2012) 0.91
Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}. J Cell Sci (2010) 0.89
Iron increases translation initiation directed by internal ribosome entry site of hepatitis C virus. Virus Genes (2008) 0.88
Rapid degradation of replication-dependent histone mRNAs largely occurs on mRNAs bound by nuclear cap-binding proteins 80 and 20. Nucleic Acids Res (2012) 0.88
Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells. Methods Enzymol (2008) 0.87
Pioneer round of translation mediated by nuclear cap-binding proteins CBP80/20 occurs during prolonged hypoxia. FEBS Lett (2007) 0.87
Quantitative proteome analysis of age-related changes in mouse gastrocnemius muscle using mTRAQ. Proteomics (2014) 0.86
Immunopurification and analysis of protein and RNA components of mRNP in mammalian cells. Methods Mol Biol (2004) 0.85
Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners. Autophagy (2015) 0.84
Nonsense-mediated translational repression involves exon junction complex downstream of premature translation termination codon. FEBS Lett (2010) 0.84
When a ribosome encounters a premature termination codon. BMB Rep (2013) 0.83
Reinvestigation of aminoacyl-tRNA synthetase core complex by affinity purification-mass spectrometry reveals TARSL2 as a potential member of the complex. PLoS One (2013) 0.80
The upstream open reading frame of cyclin-dependent kinase inhibitor 1A mRNA negatively regulates translation of the downstream main open reading frame. Biochem Biophys Res Commun (2012) 0.80
An enemy within: fly reconnaissance deploys an endonuclease to destroy nonsense-containing mRNA. Trends Cell Biol (2004) 0.80
Hepatitis C virus NS2 protein activates cellular cyclic AMP-dependent pathways. Biochem Biophys Res Commun (2007) 0.79
Non-structural protein 1 of influenza viruses inhibits rapid mRNA degradation mediated by double-stranded RNA-binding protein, staufen1. FEBS Lett (2013) 0.79
SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay. Biochim Biophys Acta (2013) 0.78
Affinity purification of long noncoding RNA-protein complexes from formaldehyde cross-linked mammalian cells. Methods Mol Biol (2015) 0.78
UPF1 learns to relax and unwind. Mol Cell (2011) 0.77
RNA turnover in eukaryotes: nucleases, pathways and analysis of mRNA decay. Preface. Methods Enzymol (2008) 0.77
New gene expression pipelines gush lncRNAs. Genome Biol (2013) 0.77
Nonsense-mediated decay: assaying for effects on selenoprotein mRNAs. Methods Enzymol (2002) 0.76
RNA-protein interactions: insight into gene function. Methods (2002) 0.76
Telomeric RNAs as a novel player in telomeric integrity. F1000 Biol Rep (2009) 0.75
Translation initiation mediated by nuclear cap-binding protein complex. BMB Rep (2016) 0.75
RNA turnover in eukaryotes: analysis of specialized and quality control RNA decay pathways. Preface. Methods Enzymol (2008) 0.75
RNA turnover in prokaryotes, archaea and organelles. Preface. Methods Enzymol (2008) 0.75