Published in Lab Invest on November 01, 2005
Ski and SnoN, potent negative regulators of TGF-beta signaling. Cell Res (2009) 2.07
SnoN in mammalian development, function and diseases. Curr Opin Pharmacol (2010) 0.98
Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3. J Biol Chem (2008) 0.92
Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development (2011) 0.84
The crystal structure of the Dachshund domain of human SnoN reveals flexibility in the putative protein interaction surface. PLoS One (2010) 0.80
Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Dev (2016) 0.76
Drosophila CORL is required for Smad2-mediated activation of Ecdysone Receptor expression in the mushroom body. Development (2012) 0.75
Longitudinal genome-wide methylation study of Roux-en-Y gastric bypass patients reveals novel CpG sites associated with essential hypertension. BMC Med Genomics (2016) 0.75
fussel (fuss)--A negative regulator of BMP signaling in Drosophila melanogaster. PLoS One (2012) 0.75
Effect of laser therapy on plasma expression of VEGF and bFGF in infants with cutaneous hemangioma. Oncol Lett (2017) 0.75
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 9.95
SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell (2008) 5.02
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (2010) 4.69
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science (2011) 4.26
Genome-scale RNAi profiling of cell division in human tissue culture cells. Nat Cell Biol (2007) 3.91
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature (2004) 3.69
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions. J Cell Biol (2010) 3.61
Stable isotope labeling by amino acids in cell culture (SILAC) and proteome quantitation of mouse embryonic stem cells to a depth of 5,111 proteins. Mol Cell Proteomics (2007) 3.60
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell (2009) 3.55
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell (2013) 3.53
Kindlin-2 controls bidirectional signaling of integrins. Genes Dev (2008) 3.15
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol (2009) 2.98
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol (2010) 2.91
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proc Natl Acad Sci U S A (2005) 2.59
Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation. Nat Med (2009) 2.51
Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo. J Exp Med (2007) 2.43
Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy. Nat Genet (2005) 2.38
The Kindlins: subcellular localization and expression during murine development. Exp Cell Res (2006) 2.36
LAD-1/variant syndrome is caused by mutations in FERMT3. Blood (2008) 2.22
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J (2011) 2.14
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood (2010) 2.04
The RGD motif in fibronectin is essential for development but dispensable for fibril assembly. J Cell Biol (2007) 1.81
Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction. PLoS Genet (2008) 1.78
Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes. J Cell Sci (2007) 1.78
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PLoS Biol (2010) 1.77
The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleus. EMBO J (2002) 1.72
Spectrum of mutations in the gene for autosomal recessive polycystic kidney disease (ARPKD/PKHD1). J Am Soc Nephrol (2003) 1.70
The human cap-binding complex is functionally connected to the nuclear RNA exosome. Nat Struct Mol Biol (2013) 1.67
Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood (2012) 1.64
Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res (2004) 1.61
Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma. Cancer Sci (2009) 1.60
Multiparameter immunofluorescence on paraffin-embedded tissue sections. Appl Immunohistochem Mol Morphol (2006) 1.59
Integrin signaling in malignant melanoma. Cancer Metastasis Rev (2005) 1.58
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J (2009) 1.51
Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration. Cancer Res (2005) 1.49
Slit3 inhibits activator protein 1-mediated migration of malignant melanoma cells. Int J Mol Med (2011) 1.49
SR protein family members display diverse activities in the formation of nascent and mature mRNPs in vivo. Mol Cell (2009) 1.45
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell (2012) 1.44
Blockade of angio-associated migratory cell protein inhibits smooth muscle cell migration and neointima formation in accelerated atherosclerosis. J Am Coll Cardiol (2008) 1.43
Stoichiometry of chromatin-associated protein complexes revealed by label-free quantitative mass spectrometry-based proteomics. Nucleic Acids Res (2012) 1.43
Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene. J Am Soc Nephrol (2002) 1.41
APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Nat Struct Mol Biol (2012) 1.40
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1. J Neurosci (2005) 1.40
PKHD1 mutations in autosomal recessive polycystic kidney disease (ARPKD). Hum Mutat (2004) 1.40
Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell (2012) 1.40
Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma. Am J Pathol (2003) 1.36
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage. J Cell Sci (2005) 1.34
Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma (2009) 1.33
Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila. J Neurosci (2005) 1.33
Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption. J Cell Biol (2011) 1.32
Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal (2011) 1.31
Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn (2008) 1.30
The molecular basis of leukocyte recruitment and its deficiencies. Mol Immunol (2012) 1.30
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol (2008) 1.27
The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells. J Cell Biol (2010) 1.26
The transcription factor TCFAP2C/AP-2gamma cooperates with CDX2 to maintain trophectoderm formation. Mol Cell Biol (2010) 1.23
The mechanism of kindlin-mediated activation of integrin αIIbβ3. Curr Biol (2013) 1.22
Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions. Blood (2009) 1.21
Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice. J Biol Chem (2007) 1.19
Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice. J Clin Invest (2006) 1.19
Snail-regulated genes in malignant melanoma. Melanoma Res (2005) 1.17
PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions. Exp Cell Res (2003) 1.16
MicroRNA miR-196a is a central regulator of HOX-B7 and BMP4 expression in malignant melanoma. Cell Mol Life Sci (2010) 1.16
Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc (2007) 1.15
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. Proc Natl Acad Sci U S A (2010) 1.15
RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo. Blood (2010) 1.14
MicroRNA miR-196a controls melanoma-associated genes by regulating HOX-C8 expression. Int J Cancer (2011) 1.12
Large-scale de novo prediction of physical protein-protein association. Mol Cell Proteomics (2011) 1.11
Iron-induced expression of bone morphogenic protein 6 in intestinal cells is the main regulator of hepatic hepcidin expression in vivo. Gastroenterology (2009) 1.11
A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat Cell Biol (2013) 1.11
Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J (2011) 1.11
Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors. PLoS One (2009) 1.10
CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules. Blood (2011) 1.10
Epigenetic events in malignant melanoma. Pigment Cell Res (2007) 1.10
Cold atmospheric plasma (CAP) changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo. PLoS One (2013) 1.09
Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase. J Cell Biol (2013) 1.09
Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma. Carcinogenesis (2005) 1.09
Consequences of loss of PINCH2 expression in mice. J Cell Sci (2005) 1.08
Bone morphogenetic protein 4 is induced in hepatocellular carcinoma by hypoxia and promotes tumour progression. J Pathol (2009) 1.08
Psychiatric comorbidity and functional impairment in a clinically referred sample of adults with attention-deficit/hyperactivity disorder (ADHD). Eur Arch Psychiatry Clin Neurosci (2007) 1.06
PKHD1 mutations in families requesting prenatal diagnosis for autosomal recessive polycystic kidney disease (ARPKD). Hum Mutat (2004) 1.06
Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice. Mol Cell Biol (2002) 1.06
A novel drug-eluting stent coated with an integrin-binding cyclic Arg-Gly-Asp peptide inhibits neointimal hyperplasia by recruiting endothelial progenitor cells. J Am Coll Cardiol (2006) 1.06
Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma. Ann Surg (2004) 1.05
Cold atmospheric plasma, a new strategy to induce senescence in melanoma cells. Exp Dermatol (2013) 1.04
Inhibition of melanoma inhibitory activity (MIA) expression in melanoma cells leads to molecular and phenotypic changes. Pigment Cell Res (2005) 1.04
Novel highly sensitive IL-10-beta-lactamase reporter mouse reveals cells of the innate immune system as a substantial source of IL-10 in vivo. J Immunol (2011) 1.03
Insulin prevents liver damage and preserves liver function in lipopolysaccharide-induced endotoxemic rats. J Hepatol (2005) 1.03
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J Cell Biol (2012) 1.03
The ARF-like GTPase ARFRP1 is essential for lipid droplet growth and is involved in the regulation of lipolysis. Mol Cell Biol (2009) 1.03
Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling. Mol Cell Neurosci (2007) 1.03
Functional implication of Netrin expression in malignant melanoma. Cell Oncol (2009) 1.02
Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res (2013) 1.02
p54nrb is a new regulator of progression of malignant melanoma. Carcinogenesis (2011) 1.01
Disruption of the latent transforming growth factor-beta binding protein-1 gene causes alteration in facial structure and influences TGF-beta bioavailability. Biochim Biophys Acta (2007) 1.01