Published in J Biochem Mol Biol on September 30, 2005
Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mol Cell (2012) 1.06
A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR. J Biol Chem (2009) 0.90
Solution structure and dynamics of ADF from Toxoplasma gondii. J Struct Biol (2011) 0.86
Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments. Biochem Biophys Res Commun (2009) 0.86
Solution structure of the N-terminal domain of a replication restart primosome factor, PriC, in Escherichia coli. Protein Sci (2013) 0.77
TvDim1 of Trichoderma virens is involved in redox-processes and confers resistance to oxidative stresses. Curr Genet (2009) 0.76
Solution structures and dynamics of ADF/cofilins UNC-60A and UNC-60B from Caenorhabditis elegans. Biochem J (2015) 0.76
Protein Structure Idealization: How accurately is it possible to model protein structures with dihedral angles? Algorithms Mol Biol (2013) 0.75
Consistent blind protein structure generation from NMR chemical shift data. Proc Natl Acad Sci U S A (2008) 6.76
Histone recognition and large-scale structural analysis of the human bromodomain family. Cell (2012) 5.15
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood (2010) 4.02
Protein production and purification. Nat Methods (2008) 3.97
Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone. Nature (2005) 3.97
Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (2011) 3.67
(E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(4-fluoro-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 3.63
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol (2011) 3.60
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature (2008) 3.39
In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo. Cancer Cell (2010) 3.05
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proc Natl Acad Sci U S A (2005) 2.59
Structural biology of human H3K9 methyltransferases. PLoS One (2010) 2.45
Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (2014) 2.23
Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. J Biol Chem (2008) 2.12
L3MBTL1 recognition of mono- and dimethylated histones. Nat Struct Mol Biol (2007) 2.12
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family. J Biol Chem (2006) 2.10
NMR data collection and analysis protocol for high-throughput protein structure determination. Proc Natl Acad Sci U S A (2005) 2.09
Structural basis for molecular recognition and presentation of histone H3 by WDR5. EMBO J (2006) 2.08
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Proc Natl Acad Sci U S A (2011) 1.99
Molecular recognition of p53 and MDM2 by USP7/HAUSP. Nat Struct Mol Biol (2006) 1.97
An NMR approach to structural proteomics. Proc Natl Acad Sci U S A (2002) 1.95
Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a. J Med Chem (2009) 1.92
Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol Cell (2005) 1.92
Structural and chemical profiling of the human cytosolic sulfotransferases. PLoS Biol (2007) 1.90
An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1. ACS Chem Biol (2013) 1.89
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res (2008) 1.85
Response of soil respiration to soil temperature and moisture in a 50-year-old oriental arborvitae plantation in China. PLoS One (2011) 1.80
Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J Biol Chem (2011) 1.79
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nat Struct Mol Biol (2012) 1.77
Recognition and specificity determinants of the human cbx chromodomains. J Biol Chem (2010) 1.76
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. J Med Chem (2010) 1.73
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol (2013) 1.72
A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease. Circ Res (2010) 1.70
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun (2012) 1.67
The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activities. J Biol Chem (2004) 1.66
Evaluation of the biocompatibility of a chitosan scaffold in mice. J Biomed Mater Res (2002) 1.62
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol Cell (2012) 1.62
Structural proteomics: toward high-throughput structural biology as a tool in functional genomics. Acc Chem Res (2003) 1.62
Enzyme genomics: Application of general enzymatic screens to discover new enzymes. FEMS Microbiol Rev (2005) 1.61
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J Biol Chem (2003) 1.61
Data mining crystallization databases: knowledge-based approaches to optimize protein crystal screens. Proteins (2003) 1.58
RIG-I forms signaling-competent filaments in an ATP-dependent, ubiquitin-independent manner. Mol Cell (2013) 1.57
Retroperitoneal laparoscopic anatrophic nephrolithotomy for large staghorn calculi. Int J Urol (2010) 1.53
The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem (2005) 1.52
Xom interacts with and stimulates transcriptional activity of LEF1/TCFs: implications for ventral cell fate determination during vertebrate embryogenesis. Cell Res (2007) 1.51
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine. Mol Cell (2008) 1.51
Rosuvastatin attenuates the elevation in blood pressure induced by overexpression of human C-reactive protein. Hypertens Res (2011) 1.50
Uniform hexagonal graphene flakes and films grown on liquid copper surface. Proc Natl Acad Sci U S A (2012) 1.49
Monomeric red fluorescent proteins with a large Stokes shift. Proc Natl Acad Sci U S A (2010) 1.47
Simultaneous prediction of protein folding and docking at high resolution. Proc Natl Acad Sci U S A (2009) 1.47
(E)-1-(4-Benzhydrylpiperazin-1-yl)-3-(3,4-dieth-oxy-phen-yl)prop-2-en-1-one ethanol monosolvate. Acta Crystallogr Sect E Struct Rep Online (2011) 1.46
Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem (2011) 1.46
Small-molecule ligands of methyl-lysine binding proteins. J Med Chem (2011) 1.45
PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Invest (2011) 1.43
PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation. Clin Cancer Res (2006) 1.43
Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem (2003) 1.41
(E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(3,4-dieth-oxy-phen-yl)prop-2-en-1-one ethanol disolvate. Acta Crystallogr Sect E Struct Rep Online (2012) 1.39
Retracted Reanalysis of the gene expression profile in chronic pancreatitis via bioinformatics methods. Eur J Med Res (2014) 1.39
Second- versus first-generation azoles for antifungal prophylaxis in hematology patients: a systematic review and meta-analysis. Ann Hematol (2013) 1.39
NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein. Proteins (2007) 1.39
Studies related to the relative thermodynamic stability of C-terminal peptidyl esters of O-hydroxy thiophenol: emergence of a doable strategy for non-cysteine ligation applicable to the chemical synthesis of glycopeptides. J Am Chem Soc (2006) 1.37
Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions? J Mol Biol (2005) 1.36
A SPOT on the chromatin landscape? Histone peptide arrays as a tool for epigenetic research. Trends Biochem Sci (2008) 1.34
Visual disability, visual function, and myopia among rural chinese secondary school children: the Xichang Pediatric Refractive Error Study (X-PRES)--report 1. Invest Ophthalmol Vis Sci (2008) 1.34
Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments. Proc Natl Acad Sci U S A (2012) 1.33
Molecular basis of Pirh2-mediated p53 ubiquitylation. Nat Struct Mol Biol (2008) 1.32
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2. Nucleic Acids Res (2009) 1.32
Structure of an atypical orphan response regulator protein supports a new phosphorylation-independent regulatory mechanism. J Biol Chem (2007) 1.30
Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation. Genes Dev (2013) 1.30
Dual-color photon-counting histogram. Biophys J (2004) 1.29
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins. J Biomol Screen (2009) 1.27
Strategies for structural proteomics of prokaryotes: Quantifying the advantages of studying orthologous proteins and of using both NMR and X-ray crystallography approaches. Proteins (2003) 1.27
Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. J Exp Bot (2012) 1.26
The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53. J Biol Chem (2007) 1.26
A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen. Mol Cell Proteomics (2012) 1.25
Total vs. proximal gastrectomy for proximal gastric cancer: a systematic review and meta-analysis. Hepatogastroenterology (2012) 1.24
High-throughput production of prokaryotic membrane proteins. J Struct Funct Genomics (2005) 1.24
The mechanics behind DNA sequence-dependent properties of the nucleosome. Nucleic Acids Res (2012) 1.23
Blind testing of routine, fully automated determination of protein structures from NMR data. Structure (2012) 1.23
Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP. J Med Chem (2013) 1.23
CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery. Clin Cancer Res (2009) 1.22
Isolation, antimicrobial resistance, and virulence genes of Pasteurella multocida strains from swine in China. J Clin Microbiol (2009) 1.22
Toward homogeneous erythropoietin: chemical synthesis of the Ala1-Gly28 glycopeptide domain by "alanine" ligation. J Am Chem Soc (2009) 1.21
MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression. FEBS Lett (2012) 1.20
A novel strategy for NMR resonance assignment and protein structure determination. J Biomol NMR (2010) 1.20
A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity. Biochem J (2009) 1.19
(E)-1-{4-[Bis(4-bromo-phen-yl)meth-yl]piperazin-1-yl}-3-(4-eth-oxy-3-meth-oxy-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.19
Persistence of side population cells with high drug efflux capacity in pancreatic cancer. World J Gastroenterol (2008) 1.18
(E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(4-methyl-phen-yl)prop-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.17
Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J Mol Biol (2007) 1.16
Partial deletions are associated with an increased risk of complete deletion in AZFc: a new insight into the role of partial AZFc deletions in male infertility. J Med Genet (2007) 1.16
NleG Type 3 effectors from enterohaemorrhagic Escherichia coli are U-Box E3 ubiquitin ligases. PLoS Pathog (2010) 1.16