Published in J Biol Chem on May 09, 2007
Phosphorylation-independent regulation of the diguanylate cyclase WspR. PLoS Biol (2008) 2.99
Molecular strategies for phosphorylation-mediated regulation of response regulator activity. Curr Opin Microbiol (2010) 1.90
Regulation of response regulator autophosphorylation through interdomain contacts. J Biol Chem (2010) 1.85
Receiver domain structure and function in response regulator proteins. Curr Opin Microbiol (2010) 1.77
The aspartate-less receiver (ALR) domains: distribution, structure and function. PLoS Pathog (2015) 1.43
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes. BMC Genomics (2011) 1.38
Amino acids important for DNA recognition by the response regulator OmpR. J Biol Chem (2008) 1.33
Response regulator heterodimer formation controls a key stage in Streptomyces development. PLoS Genet (2014) 0.96
Transcriptional and post-transcriptional regulation of the GmaR antirepressor governs temperature-dependent control of flagellar motility in Listeria monocytogenes. Mol Microbiol (2009) 0.92
The atypical OmpR/PhoB response regulator ChxR from Chlamydia trachomatis forms homodimers in vivo and binds a direct repeat of nucleotide sequences. J Bacteriol (2010) 0.88
Molecular Mechanisms of Two-Component Signal Transduction. J Mol Biol (2016) 0.87
Intermolecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric reverse-protonation and two-dimensional NOESY. Biochemistry (2010) 0.85
Response to metronidazole and oxidative stress is mediated through homeostatic regulator HsrA (HP1043) in Helicobacter pylori. J Bacteriol (2013) 0.84
The atypical response regulator protein ChxR has structural characteristics and dimer interface interactions that are unique within the OmpR/PhoB subfamily. J Biol Chem (2011) 0.83
Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio (2014) 0.83
Mutations to essential orphan response regulator HP1043 of Helicobacter pylori result in growth-stage regulatory defects. Infect Immun (2013) 0.82
Atypical OmpR/PhoB subfamily response regulator GlnR of actinomycetes functions as a homodimer, stabilized by the unphosphorylated conserved Asp-focused charge interactions. J Biol Chem (2014) 0.81
Structural insights into the dimerization of the response regulator ComE from Streptococcus pneumoniae. Nucleic Acids Res (2014) 0.81
Backbone dynamics of an atypical orphan response regulator protein, Helicobacter pylori 1043. Mol Cells (2013) 0.80
VirS, an OmpR/PhoB subfamily response regulator, is required for activation of vapA gene expression in Rhodococcus equi. BMC Microbiol (2014) 0.80
Expression, purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of a Chlamydia trachomatis OmpR/PhoB-subfamily response regulator homolog, ChxR. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.78
Structural analysis of the DNA-binding domain of the Helicobacter pylori response regulator ArsR. J Biol Chem (2008) 0.78
Atypical response regulator ChxR from Chlamydia trachomatis is structurally poised for DNA binding. PLoS One (2014) 0.76
To ∼P or Not to ∼P? Non-canonical activation by two-component response regulators. Mol Microbiol (2016) 0.75
NMR Study Reveals the Receiver Domain of Arabidopsis ETHYLENE RESPONSE1 Ethylene Receptor as an Atypical Type Response Regulator. PLoS One (2016) 0.75
SO2426 is a positive regulator of siderophore expression in Shewanella oneidensis MR-1. BMC Microbiol (2011) 0.75
Dual Repression of the Multidrug Efflux Pump CmeABC by CosR and CmeR in Campylobacter jejuni. Front Microbiol (2016) 0.75
Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites. Sci Rep (2017) 0.75
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Mol Cell (2003) 5.06
Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Science (2008) 4.36
Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone. Nature (2005) 3.97
Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. EMBO J (2004) 2.53
Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int J Cancer (2011) 2.42
S. pombe genome deletion project: an update. Cell Cycle (2010) 2.34
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell (2009) 2.32
Overcoming artifacts from metallic orthopedic implants at high-field-strength MR imaging and multi-detector CT. Radiographics (2007) 2.08
Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A (2008) 2.01
An NMR approach to structural proteomics. Proc Natl Acad Sci U S A (2002) 1.95
Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. Mol Cell (2005) 1.92
Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell (2010) 1.82
CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms. Nat Immunol (2009) 1.70
Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins. Prog Nucl Magn Reson Spectrosc (2009) 1.57
Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Sci (2011) 1.57
Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules. Nature (2003) 1.51
Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Proc Natl Acad Sci U S A (2007) 1.50
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression. Cancer Res (2012) 1.37
Circadian fluctuation of mean ocular perfusion pressure is a consistent risk factor for normal-tension glaucoma. Invest Ophthalmol Vis Sci (2007) 1.36
Structure of PP4397 reveals the molecular basis for different c-di-GMP binding modes by Pilz domain proteins. J Mol Biol (2010) 1.34
A genome-wide resource of cell cycle and cell shape genes of fission yeast. Open Biol (2013) 1.32
Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism. J Biol Chem (2011) 1.30
Motions on the millisecond time scale and multiple conformations of HIV-1 capsid protein: implications for structural polymorphism of CA assemblies. J Am Chem Soc (2012) 1.28
Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. J Biochem Mol Biol (2004) 1.28
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane. FASEB J (2011) 1.25
Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance. DNA Repair (Amst) (2009) 1.21
Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions. Mol Immunol (2008) 1.15
Effect of nocturnal blood pressure reduction on circadian fluctuation of mean ocular perfusion pressure: a risk factor for normal tension glaucoma. Invest Ophthalmol Vis Sci (2006) 1.14
Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling. J Mol Biol (2005) 1.14
Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering. Proc Natl Acad Sci U S A (2012) 1.11
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Mol Cell (2011) 1.11
Corneal dystrophy-associated R124H mutation disrupts TGFBI interaction with Periostin and causes mislocalization to the lysosome. J Biol Chem (2009) 1.10
Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Mol Biol Cell (2010) 1.10
Rapid preparation of RNA samples for NMR spectroscopy and X-ray crystallography. Nucleic Acids Res (2004) 1.09
Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway. Neoplasia (2011) 1.08
Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast. Genes Dev (2010) 1.08
Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. Proc Natl Acad Sci U S A (2010) 1.08
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nat Struct Mol Biol (2010) 1.06
Solution structure and cell selectivity of piscidin 1 and its analogues. Biochemistry (2007) 1.06
Cyclomaltodextrinase, neopullulanase, and maltogenic amylase are nearly indistinguishable from each other. J Biol Chem (2002) 1.06
Crystal structure of hyperthermophilic esterase EstE1 and the relationship between its dimerization and thermostability properties. BMC Struct Biol (2007) 1.06
Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer. Mol Cancer (2011) 1.05
Tsc-22 enhances TGF-beta signaling by associating with Smad4 and induces erythroid cell differentiation. Mol Cell Biochem (2005) 1.05
A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe. Toxicol Sci (2008) 1.04
Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC. J Biol Chem (2011) 1.03
RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization. J Leukoc Biol (2006) 1.03
Structure of human PRL-3, the phosphatase associated with cancer metastasis. FEBS Lett (2004) 1.02
The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6. Cancer Prev Res (Phila) (2011) 1.02
An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells. J Exp Med (2007) 1.02
Antibiotic activity and structural analysis of the scorpion-derived antimicrobial peptide IsCT and its analogs. Biochem Biophys Res Commun (2004) 1.02
PACSY, a relational database management system for protein structure and chemical shift analysis. J Biomol NMR (2012) 1.01
Role of magnetic resonance imaging in entrapment and compressive neuropathy--what, where, and how to see the peripheral nerves on the musculoskeletal magnetic resonance image: part 2. Upper extremity. Eur Radiol (2006) 1.01
Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK. Biochem Biophys Res Commun (2009) 1.01
The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis. Genes Chromosomes Cancer (2012) 1.00
Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition. Cancer Lett (2013) 1.00
Identification of lipopolysaccharide-binding peptide regions within HMGB1 and their effects on subclinical endotoxemia in a mouse model. Eur J Immunol (2011) 0.99
Prevalence of granular corneal dystrophy type 2 (Avellino corneal dystrophy) in the Korean population. Ophthalmic Epidemiol (2010) 0.99
In vivo tracking of human mesenchymal stem cells in experimental stroke. Cell Transplant (2008) 0.99
Parkin directly modulates 26S proteasome activity. J Neurosci (2010) 0.98
Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus. Int J Biol Macromol (2008) 0.97
Chronic tibiofibular syndesmosis injury of ankle: evaluation with contrast-enhanced fat-suppressed 3D fast spoiled gradient-recalled acquisition in the steady state MR imaging. Radiology (2007) 0.97
Efficacy of latanoprost in patients with chronic angle-closure glaucoma and no visible ciliary-body face: a preliminary study. J Ocul Pharmacol Ther (2005) 0.96
Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. Nat Struct Mol Biol (2011) 0.96
Conversion shift of D-fructose to D-psicose for enzyme-catalyzed epimerization by addition of borate. Appl Environ Microbiol (2008) 0.95
Decreased catalase expression and increased susceptibility to oxidative stress in primary cultured corneal fibroblasts from patients with granular corneal dystrophy type II. Am J Pathol (2009) 0.95
Two bacterial entophytes eliciting both plant growth promotion and plant defense on pepper (Capsicum annuum L.). J Microbiol Biotechnol (2007) 0.95
Immunostimulatory oligodeoxynucleotide isolated from genome wide screening of Mycobacterium bovis chromosomal DNA. Mol Immunol (2006) 0.95
Structure and function of papiliocin with antimicrobial and anti-inflammatory activities isolated from the swallowtail butterfly, Papilio xuthus. J Biol Chem (2011) 0.94
Is ineffective esophageal motility associated with gastropharyngeal reflux disease? World J Gastroenterol (2008) 0.94
APOBEC2 is a monomer in solution: implications for APOBEC3G models. Biochemistry (2012) 0.93
Determination of multicomponent protein structures in solution using global orientation and shape restraints. J Am Chem Soc (2009) 0.93
Salt resistance and synergistic effect with vancomycin of alpha-helical antimicrobial peptide P18. Biochem Biophys Res Commun (2002) 0.93
Structural snapshots of heparin depolymerization by heparin lyase I. J Biol Chem (2009) 0.92
Mean curvature as a major determinant of beta-sheet propensity. Bioinformatics (2005) 0.92
Biochemical characterization and FAD-binding analysis of oleate hydratase from Macrococcus caseolyticus. Biochimie (2011) 0.92
Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity. J Biol Chem (2010) 0.92
Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions. Biochim Biophys Acta (2007) 0.92
Cell selectivity and mechanism of action of antimicrobial model peptides containing peptoid residues. Biochemistry (2005) 0.91
The oligomeric status of syndecan-4 regulates syndecan-4 interaction with alpha-actinin. Eur J Cell Biol (2008) 0.91
Stereospecificity of ginsenoside Rg3 action on ion channels. Mol Cells (2004) 0.91
Macro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphase. J Biol Chem (2011) 0.91
The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily. J Biol Chem (2009) 0.91
Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1. Bioorg Med Chem (2013) 0.91
RGS14 is a centrosomal and nuclear cytoplasmic shuttling protein that traffics to promyelocytic leukemia nuclear bodies following heat shock. J Biol Chem (2004) 0.91
The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination. J Biol Chem (2010) 0.91
Regulation of inositol phospholipid binding and signaling through syndecan-4. J Biol Chem (2002) 0.91