Published in Cancer Res on October 01, 2005
Evolution of cooperation among tumor cells. Proc Natl Acad Sci U S A (2006) 2.63
Thrombospondins in cancer. Cell Mol Life Sci (2008) 2.08
The thrombospondins. Cold Spring Harb Perspect Biol (2011) 1.52
Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1. J Virol (2007) 1.32
Thrombospondin-based antiangiogenic therapy. Microvasc Res (2007) 1.26
Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1. Proc Natl Acad Sci U S A (2009) 1.12
Contribution of host-derived tissue factor to tumor neovascularization. Arterioscler Thromb Vasc Biol (2008) 1.08
Thrombospondin and apoptosis: molecular mechanisms and use for design of complementation treatments. Curr Drug Targets (2008) 0.97
Thrombospondin-1 is a critical effector of oncosuppressive activity of sst2 somatostatin receptor on pancreatic cancer. Proc Natl Acad Sci U S A (2009) 0.95
The role of the tumor microenvironment in regulating angiogenesis. Cold Spring Harb Perspect Med (2012) 0.93
COX-2 overexpression increases malignant potential of human glioma cells through Id1. Oncotarget (2014) 0.93
Tenascin-W is a specific marker of glioma-associated blood vessels and stimulates angiogenesis in vitro. FASEB J (2009) 0.90
Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin. J Biol Chem (2014) 0.89
3'LIFE: a functional assay to detect miRNA targets in high-throughput. Nucleic Acids Res (2014) 0.89
ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities. Mol Ther (2014) 0.82
Stromal fibroblast activation and their potential association with uterine fibroids (Review). Oncol Lett (2014) 0.81
Introduction to the tumour microenvironment review series. J Cell Mol Med (2009) 0.80
First steps in experimental cancer evolution. Evol Appl (2013) 0.79
Thrombospondin-1 is a putative target gene of Runx2 and Runx3. Int J Mol Sci (2013) 0.77
H-Ras increases release of sphingosine resulting in down-regulation of TSP-1 in non-transformed cells. Int J Exp Pathol (2012) 0.75
Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras. Oncotarget (2016) 0.75
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell (2005) 7.41
Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells. Nat Cell Biol (2008) 7.30
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell (2006) 5.88
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nat Rev Cancer (2002) 5.02
Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science (2006) 4.79
Id proteins in development, cell cycle and cancer. Trends Cell Biol (2003) 4.53
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell (2008) 4.51
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature (2004) 4.41
Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nat Rev Cancer (2010) 3.95
Id family of helix-loop-helix proteins in cancer. Nat Rev Cancer (2005) 3.80
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat Med (2005) 3.60
An admissions OSCE: the multiple mini-interview. Med Educ (2004) 3.28
Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell (2011) 2.96
Association between a medical school admission process using the multiple mini-interview and national licensing examination scores. JAMA (2012) 2.95
ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc Natl Acad Sci U S A (2007) 2.85
Microvesicles as mediators of intercellular communication in cancer--the emerging science of cellular 'debris'. Semin Immunopathol (2011) 2.78
Microvesicles: messengers and mediators of tumor progression. Cell Cycle (2009) 2.66
Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR. Proc Natl Acad Sci U S A (2009) 2.66
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes Dev (2007) 2.60
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nat Biotechnol (2010) 2.54
Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science (2004) 2.53
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell (2003) 2.53
Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma. Cancer Cell (2012) 2.50
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal. Nature (2010) 2.36
Predictive validity of the multiple mini-interview for selecting medical trainees. Med Educ (2009) 2.31
Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy. Circ Res (2004) 2.31
Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell (2011) 2.29
The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice. Am J Pathol (2002) 2.22
Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. Proc Natl Acad Sci U S A (2004) 2.19
A role for survivin in chemoresistance of endothelial cells mediated by VEGF. Proc Natl Acad Sci U S A (2002) 2.16
High levels of Id1 expression define B1 type adult neural stem cells. Cell Stem Cell (2009) 2.15
Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells. Proc Natl Acad Sci U S A (2007) 2.02
Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. Cancer Res (2007) 1.96
Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1. Cancer Cell (2013) 1.93
Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol (2012) 1.89
The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. Am J Pathol (2004) 1.88
Selective killing of tumor neovasculature paradoxically improves chemotherapy delivery to tumors. Cancer Res (2010) 1.80
Thrombospondins 1 and 2 function as inhibitors of angiogenesis. Matrix Biol (2003) 1.76
Multiple mini-interviews predict clerkship and licensing examination performance. Med Educ (2007) 1.71
SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts. J Biol Chem (2007) 1.68
Mad2 phosphorylation regulates its association with Mad1 and the APC/C. EMBO J (2003) 1.68
Dynamic reciprocity in the wound microenvironment. Wound Repair Regen (2011) 1.62
The ability of the multiple mini-interview to predict preclerkship performance in medical school. Acad Med (2004) 1.62
Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo. Proc Natl Acad Sci U S A (2008) 1.60
Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody. Cancer Res (2006) 1.56
Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell (2007) 1.56
Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression. Biochim Biophys Acta (2009) 1.54
Matricellular proteins as modulators of wound healing and the foreign body response. Thromb Haemost (2003) 1.52
Id1 restrains p21 expression to control endothelial progenitor cell formation. PLoS One (2007) 1.52
Antiproliferative, antiangiogenic and proapoptotic activity of h-R3: A humanized anti-EGFR antibody. Int J Cancer (2002) 1.49
Interactions between CD47 and thrombospondin reduce inflammation. J Immunol (2007) 1.46
Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9. J Leukoc Biol (2009) 1.41
Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis. Invest Ophthalmol Vis Sci (2004) 1.40
Thrombospondins function as regulators of angiogenesis. J Cell Commun Signal (2009) 1.40
Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis. Matrix Biol (2009) 1.40
High-frequency Doppler ultrasound monitors the effects of antivascular therapy on tumor blood flow. Cancer Res (2002) 1.40
Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. J Clin Invest (2006) 1.35
The relationship between interviewers' characteristics and ratings assigned during a multiple mini-interview. Acad Med (2004) 1.35
Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). J Cell Physiol (2007) 1.35
Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo. Nat Biotechnol (2008) 1.33
Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I. PLoS One (2007) 1.31
What do oncogenic mutations have to do with angiogenesis/vascular dependence of tumors? Cancer Res (2002) 1.27
Thrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism. Mol Biol Cell (2002) 1.26
Thrombospondin-2 modulates extracellular matrix remodeling during physiological angiogenesis. Am J Pathol (2008) 1.25
Glycosylation mediates up-regulation of a potent antiangiogenic and proatherogenic protein, thrombospondin-1, by glucose in vascular smooth muscle cells. J Biol Chem (2006) 1.21
Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer. Blood (2012) 1.20
New technologies for the detection of circulating tumour cells. Br Med Bull (2010) 1.20
Utilization of bone marrow-derived endothelial cell precursors in spontaneous prostate tumors varies with tumor grade. Cancer Res (2004) 1.20
Thrombospondin-4 regulates vascular inflammation and atherogenesis. Circ Res (2010) 1.19
Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis. Cancer Res (2008) 1.19
Tissue factor in cancer and angiogenesis: the molecular link between genetic tumor progression, tumor neovascularization, and cancer coagulopathy. Semin Thromb Hemost (2006) 1.18
Proteolysis of cell-surface tissue transglutaminase by matrix metalloproteinase-2 contributes to the adhesive defect and matrix abnormalities in thrombospondin-2-null fibroblasts and mice. Am J Pathol (2005) 1.17
Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen. Am J Pathol (2008) 1.17
Oncogenes, trousseau syndrome, and cancer-related changes in the coagulome of mice and humans. Cancer Res (2006) 1.16
The secreted protein thrombospondin 2 is an autocrine inhibitor of marrow stromal cell proliferation. J Bone Miner Res (2002) 1.15
Oncogenic extracellular vesicles in brain tumor progression. Front Physiol (2012) 1.15
Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice. Blood (2002) 1.14
Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells. Blood (2010) 1.14
Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas. Proc Natl Acad Sci U S A (2008) 1.13
Mice with a deletion in the first intron of the Col1a1 gene develop age-dependent aortic dissection and rupture. Circ Res (2003) 1.12
Id1 maintains embryonic stem cell self-renewal by up-regulation of Nanog and repression of Brachyury expression. Stem Cells Dev (2011) 1.11
Thrombospondin 2 levels are increased in aged mice: consequences for cutaneous wound healing and angiogenesis. Matrix Biol (2004) 1.11
Calculation of quantum-mechanical descriptors for QSPR at the DFT level: is it necessary? J Chem Inf Model (2008) 1.09
Contribution of host-derived tissue factor to tumor neovascularization. Arterioscler Thromb Vasc Biol (2008) 1.08
Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization. PLoS One (2007) 1.08
High-frequency 3-D color-flow imaging of the microcirculation. Ultrasound Med Biol (2003) 1.07
Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors. Proc Natl Acad Sci U S A (2003) 1.07
Oncogenes and tumor angiogenesis: the question of vascular "supply" and vascular "demand". Semin Cancer Biol (2004) 1.06
pH-sensitive polymers that enhance intracellular drug delivery in vivo. J Control Release (2002) 1.05
Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials. Am J Pathol (2003) 1.04
Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors. EMBO J (2003) 1.04
Mice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties of bone and have accelerated development of the femoral head. Mol Cell Biol (2005) 1.03
Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells. Mol Biol Cell (2007) 1.03
Cancer cells preferentially lose small chromosomes. Int J Cancer (2012) 1.02
Tissue factor in tumour progression. Best Pract Res Clin Haematol (2009) 1.00
Absence of thrombospondin-2 causes age-related dilated cardiomyopathy. Circulation (2009) 1.00