Published in G3 (Bethesda) on August 09, 2016
GO::TermFinder--open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes. Bioinformatics (2004) 20.23
The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol (2007) 18.33
The genetic landscape of a cell. Science (2010) 16.52
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol (2001) 6.80
Getting started with yeast. Methods Enzymol (2002) 6.60
A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis. Genes Dev (1995) 4.93
Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae. Genetics (1990) 4.63
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science (1996) 4.47
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins. Mol Cell Proteomics (2007) 4.28
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr Biol (2005) 3.77
MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc Natl Acad Sci U S A (1997) 3.42
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell (2002) 3.24
Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat Methods (2006) 3.12
The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell (2007) 3.04
Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nat Rev Mol Cell Biol (2013) 3.01
The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat Struct Mol Biol (2004) 2.87
The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins. Mol Biol Cell (1999) 2.75
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science (2009) 2.69
Haploid plants produced by centromere-mediated genome elimination. Nature (2010) 2.57
Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J (1995) 2.38
Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J (2001) 2.31
Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling. EMBO J (2009) 2.13
The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain. Mol Cell Biol (2000) 2.08
Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. Mol Cell (2013) 2.06
Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor. Cell (2014) 2.03
Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores. Curr Biol (2012) 2.00
KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint. Curr Biol (2011) 1.98
Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol (2000) 1.96
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components. Nat Cell Biol (2012) 1.94
The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol (2002) 1.89
Mad2 and Mad3 cooperate to arrest budding yeast in mitosis. Curr Biol (2011) 1.79
Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint. Curr Biol (2012) 1.77
Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation. Nat Cell Biol (2011) 1.69
Tracking spindle checkpoint signals from kinetochores to APC/C. Trends Biochem Sci (2013) 1.66
Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. Genes Dev (2014) 1.65
Structure, function and mechanism of the anaphase promoting complex (APC/C). Q Rev Biophys (2010) 1.58
Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling. Elife (2013) 1.52
The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet (2011) 1.41
Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer. PLoS Biol (2008) 1.41
The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signalling. Nat Cell Biol (2015) 1.39
Molecular architecture and assembly of the yeast kinetochore MIND complex. J Cell Biol (2010) 1.36
Release of Mps1 from kinetochores is crucial for timely anaphase onset. J Cell Biol (2010) 1.33
DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet (2008) 1.31
De novo kinetochore assembly requires the centromeric histone H3 variant. Mol Biol Cell (2005) 1.30
ScreenMill: a freely available software suite for growth measurement, analysis and visualization of high-throughput screen data. BMC Bioinformatics (2010) 1.30
Determinants of robustness in spindle assembly checkpoint signalling. Nat Cell Biol (2013) 1.28
Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics (2005) 1.26
Tension sensing by Aurora B kinase is independent of survivin-based centromere localization. Nature (2013) 1.24
Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae. Eukaryot Cell (2005) 1.24
Csi1 links centromeres to the nuclear envelope for centromere clustering. J Cell Biol (2012) 1.22
A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO J (2013) 1.21
Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem (2009) 1.15
Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res (2010) 1.14
Accumulation of Mad2-Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae. J Cell Biol (2006) 1.11
Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes. PLoS One (2007) 1.06
N-terminal regions of Mps1 kinase determine functional bifurcation. J Cell Biol (2010) 1.03
Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores. EMBO Rep (2014) 1.01
Centromere-tethered Mps1 pombe homolog (Mph1) kinase is a sufficient marker for recruitment of the spindle checkpoint protein Bub1, but not Mad1. Proc Natl Acad Sci U S A (2011) 1.01
A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment. EMBO Rep (2014) 1.00
Mitosis-specific regulation of nuclear transport by the spindle assembly checkpoint protein Mad1p. Mol Cell (2012) 0.99
Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres. Elife (2014) 0.99
The nuclear export factor Xpo1p targets Mad1p to kinetochores in yeast. J Cell Biol (2009) 0.97
A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A. J Cell Biol (2014) 0.92
Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complex. J Biol Chem (2013) 0.90
Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint. J Cell Biol (2014) 0.89
A Golgi-localized pool of the mitotic checkpoint component Mad1 controls integrin secretion and cell migration. Curr Biol (2014) 0.87
Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment. Proc Natl Acad Sci U S A (2015) 0.86
Cdc14 inhibition by the spindle assembly checkpoint prevents unscheduled centrosome separation in budding yeast. Mol Biol Cell (2009) 0.82
Localization and function of budding yeast CENP-A depends upon kinetochore protein interactions and is independent of canonical centromere sequence. Cell Rep (2014) 0.78
Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization. Proc Natl Acad Sci U S A (2015) 0.78
ScreenTroll: a searchable database to compare genome-wide yeast screens. Database (Oxford) (2012) 0.77
Synthetic protein interactions reveal a functional map of the cell. Elife (2016) 0.77
The Mps1 kinase modulates the recruitment and activity of Cnn1(CENP-T) at Saccharomyces cerevisiae kinetochores. Genetics (2015) 0.77