Published in CMAJ on October 11, 2005
Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels. The Prospective Pravastatin Pooling project. Eur Heart J (2002) 1.98
The Beta-Blocker Pooling Project (BBPP): subgroup findings from randomized trials in post infarction patients. The Beta-Blocker Pooling Project Research Group. Eur Heart J (1988) 1.50
Commentary: relative treatment effects are consistent across the spectrum of underlying risks...usually. Int J Epidemiol (2002) 1.36
Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA (2005) 23.44
Randomized trials stopped early for benefit: a systematic review. JAMA (2005) 8.43
A guide for the design and conduct of self-administered surveys of clinicians. CMAJ (2008) 6.72
Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA (2009) 6.06
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90
Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med (2008) 5.06
The association between renal replacement therapy modality and long-term outcomes among critically ill adults with acute kidney injury: a retrospective cohort study*. Crit Care Med (2014) 3.29
A multifaceted intervention for quality improvement in a network of intensive care units: a cluster randomized trial. JAMA (2011) 3.08
Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med (2010) 2.88
Association of ICU or hospital admission with unintentional discontinuation of medications for chronic diseases. JAMA (2011) 2.67
A systematic review of the Charlson comorbidity index using Canadian administrative databases: a perspective on risk adjustment in critical care research. J Crit Care (2005) 2.62
Medical admission order sets to improve deep vein thrombosis prophylaxis rates and other outcomes. J Hosp Med (2009) 2.49
Use of non-invasive ventilation to wean critically ill adults off invasive ventilation: meta-analysis and systematic review. BMJ (2009) 2.44
The design and interpretation of pilot trials in clinical research in critical care. Crit Care Med (2009) 2.38
Mortality predictions in the intensive care unit: comparing physicians with scoring systems. Crit Care Med (2006) 2.29
Variation in use of intensive care for adults with diabetic ketoacidosis*. Crit Care Med (2012) 2.24
Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials. Am J Respir Crit Care Med (2012) 2.15
Prophylactic magnesium for improving neurologic outcome after aneurysmal subarachnoid hemorrhage: systematic review and meta-analysis. J Crit Care (2012) 2.08
Reducing time-to-treatment decreases mortality of trauma patients with acute subdural hematoma. Ann Surg (2011) 2.06
Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience. Vaccine (2010) 1.91
Sex-and age-based differences in the delivery and outcomes of critical care. CMAJ (2007) 1.91
Bilevel noninvasive positive pressure ventilation for acute respiratory failure: survey of Ontario practice. Crit Care Med (2005) 1.85
Noninvasive ventilation as a weaning strategy for mechanical ventilation in adults with respiratory failure: a Cochrane systematic review. CMAJ (2013) 1.82
Organ donation after death in Ontario: a population-based cohort study. CMAJ (2013) 1.79
High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis. Crit Care Med (2010) 1.77
Quality of professional society guidelines and consensus conference statements in critical care. Crit Care Med (2008) 1.74
Determination of neurologic prognosis and clinical decision making in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons, and neurologists. Crit Care Med (2013) 1.72
Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study. CMAJ (2011) 1.72
Noninvasive ventilation for acute respiratory failure near the end of life. Crit Care Med (2008) 1.65
Access to urban acute care services in high- vs. middle-income countries: an analysis of seven cities. Intensive Care Med (2013) 1.64
A meta-analysis of noninvasive weaning to facilitate liberation from mechanical ventilation. Can J Anaesth (2006) 1.62
Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis? Crit Care (2006) 1.61
Abstract reporting in randomized clinical trials of acute lung injury: an audit and assessment of a quality of reporting score. Crit Care Med (2005) 1.61
The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: a randomized double-blind placebo controlled clinical trial. Intensive Care Med (2009) 1.61
Pay for performance in the intensive care unit--opportunity or threat? Crit Care Med (2009) 1.55
Knowledge translation interventions for critically ill patients: a systematic review*. Crit Care Med (2013) 1.53
Improving use of targeted temperature management after out-of-hospital cardiac arrest: a stepped wedge cluster randomized controlled trial. Crit Care Med (2015) 1.52
Scarcity: the context of rationing in an Ontario ICU. Crit Care Med (2013) 1.47
Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data. BMC Med Res Methodol (2007) 1.47
The ratio of means method as an alternative to mean differences for analyzing continuous outcome variables in meta-analysis: a simulation study. BMC Med Res Methodol (2008) 1.46
Percutaneous dilatational tracheostomy: mostly safe, but do benefits outweigh risks? Crit Care (2014) 1.43
Targeted temperature management processes and outcomes after out-of-hospital cardiac arrest: an observational cohort study*. Crit Care Med (2014) 1.43
Economic evaluation of decompressive craniectomy versus barbiturate coma for refractory intracranial hypertension following traumatic brain injury. Crit Care Med (2014) 1.42
Coenrollment in a randomized trial of high-frequency oscillation: prevalence, patterns, predictors, and outcomes*. Crit Care Med (2015) 1.41
Outcomes of interfacility critical care adult patient transport: a systematic review. Crit Care (2006) 1.40
The use of wireless e-mail to improve healthcare team communication. J Am Med Inform Assoc (2009) 1.39
An official American Thoracic Society systematic review: the association between health insurance status and access, care delivery, and outcomes for patients who are critically ill. Am J Respir Crit Care Med (2010) 1.32
Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis. Crit Care (2012) 1.28
Clinical review: critical care in the global context--disparities in burden of illness, access, and economics. Crit Care (2008) 1.26
The accuracy of administrative data for identifying the presence and timing of admission to intensive care units in a Canadian province. Med Care (2012) 1.22
Tracheostomy timing in traumatic brain injury: a propensity-matched cohort study. J Trauma Acute Care Surg (2014) 1.22
An official American Thoracic Society policy statement: pay-for-performance in pulmonary, critical care, and sleep medicine. Am J Respir Crit Care Med (2010) 1.20
Critical care trainees' career goals and needs: A Canadian survey. Can Respir J (2014) 1.18
The effect of telemedicine in critically ill patients: systematic review and meta-analysis. Crit Care (2012) 1.15
Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11
Routine chest x-rays in intensive care units: a systematic review and meta-analysis. Crit Care (2012) 1.11
Predictors of adopting therapeutic hypothermia for post-cardiac arrest patients among Canadian emergency and critical care physicians. Resuscitation (2009) 1.11
Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. Trials (2013) 1.07
Ratio of means for analyzing continuous outcomes in meta-analysis performed as well as mean difference methods. J Clin Epidemiol (2011) 1.05
Pressure and volume limited ventilation for the ventilatory management of patients with acute lung injury: a systematic review and meta-analysis. PLoS One (2011) 1.02
Utility and safety of draining pleural effusions in mechanically ventilated patients: a systematic review and meta-analysis. Crit Care (2011) 1.02
Intracranial pressure monitoring in severe traumatic brain injury: results from the American College of Surgeons Trauma Quality Improvement Program. J Neurotrauma (2013) 0.99
Registration and design alterations of clinical trials in critical care: a cross-sectional observational study. Intensive Care Med (2014) 0.99
Predicting neurologic outcome after targeted temperature management for cardiac arrest: systematic review and meta-analysis. Crit Care Med (2014) 0.98
Timing the initiation of renal replacement therapy for acute kidney injury in Canadian intensive care units: a multicentre observational study. Can J Anaesth (2012) 0.98
Emergency department length of stay for patients requiring mechanical ventilation: a prospective observational study. Scand J Trauma Resusc Emerg Med (2012) 0.97
Survey of information technology in Intensive Care Units in Ontario, Canada. BMC Med Inform Decis Mak (2008) 0.96
Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with respiratory failure. Cochrane Database Syst Rev (2013) 0.90
Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2). Trials (2009) 0.89
High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome. Cochrane Database Syst Rev (2013) 0.89
Epidemiology of acute kidney injury in Canadian critical care units: a prospective cohort study. Can J Anaesth (2012) 0.89
Blood pressure targets for vasopressor therapy: a systematic review. Shock (2015) 0.89
An innovative telemedicine knowledge translation program to improve quality of care in intensive care units: protocol for a cluster randomized pragmatic trial. Implement Sci (2009) 0.89
Statins, bugs and prophylaxis: intriguing possibilities. Crit Care (2006) 0.88
Drotrecogin alfa (activated): down and not out, but not really in either. Crit Care (2006) 0.87
Vasopressor administration and sepsis: a survey of Canadian intensivists. J Crit Care (2011) 0.87
Variation of arterial and central venous catheter use in United States intensive care units. Anesthesiology (2014) 0.86
Lost in (knowledge) translation: "All breakthrough, no follow through"? Crit Care Med (2008) 0.86
Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care: The WikiTrauma Interrupted Time Series Protocol. JMIR Res Protoc (2015) 0.85
Surrogate decision makers' attitudes towards research decision making for critically ill patients. Intensive Care Med (2012) 0.85
Structure, Organization, and Delivery of Critical Care in Asian ICUs. Crit Care Med (2016) 0.84
Considering the vulnerabilities of surrogate decision-makers when obtaining consent for critical care research. Intensive Care Med (2011) 0.84
Ratio of geometric means to analyze continuous outcomes in meta-analysis: comparison to mean differences and ratio of arithmetic means using empiric data and simulation. Stat Med (2012) 0.84
Economics of ICU organization and management. Crit Care Clin (2011) 0.84
Statins do not prevent acute organ failure in ventilated ICU patients: single-centre retrospective cohort study. Crit Care (2011) 0.84
Update in critical care 2007. Am J Respir Crit Care Med (2008) 0.84