Published in Intensive Care Med on April 16, 2014
Comparison of registered and published outcomes in randomized controlled trials: a systematic review. BMC Med (2015) 1.01
Retracted How blockchain-timestamped protocols could improve the trustworthiness of medical science. F1000Res (2016) 0.90
The efficacy of activated protein C for the treatment of sepsis: incorporating observational evidence with a Bayesian approach. BMJ Open (2015) 0.80
Do emergency medicine journals promote trial registration and adherence to reporting guidelines? A survey of "Instructions for Authors". Scand J Trauma Resusc Emerg Med (2016) 0.75
Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA (2009) 6.06
Has mortality from acute respiratory distress syndrome decreased over time?: A systematic review. Am J Respir Crit Care Med (2008) 5.06
Incidence, risk factors and consequences of ICU delirium. Intensive Care Med (2006) 4.82
The Pediatric Early Warning System score: a severity of illness score to predict urgent medical need in hospitalized children. J Crit Care (2006) 3.24
Hypocapnia. N Engl J Med (2002) 2.67
Association of ICU or hospital admission with unintentional discontinuation of medications for chronic diseases. JAMA (2011) 2.67
A systematic review of the Charlson comorbidity index using Canadian administrative databases: a perspective on risk adjustment in critical care research. J Crit Care (2005) 2.62
Atelectasis causes alveolar injury in nonatelectatic lung regions. Am J Respir Crit Care Med (2006) 2.56
Hypocapnia and the injured brain: more harm than benefit. Crit Care Med (2010) 2.35
Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med (2003) 2.31
Variation in use of intensive care for adults with diabetic ketoacidosis*. Crit Care Med (2012) 2.24
Integrating mortality and morbidity outcomes: using quality-adjusted life years in critical care trials. Am J Respir Crit Care Med (2012) 2.15
Lung-protective ventilation in the operating room: time to implement? Anesthesiology (2014) 2.15
Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates. Anesth Analg (2010) 2.09
Prophylactic magnesium for improving neurologic outcome after aneurysmal subarachnoid hemorrhage: systematic review and meta-analysis. J Crit Care (2012) 2.08
Reducing time-to-treatment decreases mortality of trauma patients with acute subdural hematoma. Ann Surg (2011) 2.06
Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med (2003) 2.03
Pediatric in-intensive-care-unit cardiac arrest: incidence, survival, and predictive factors. Crit Care Med (2006) 1.97
Is a mass immunization program for pandemic (H1N1) 2009 good value for money? Evidence from the Canadian Experience. Vaccine (2010) 1.91
Organ donation after death in Ontario: a population-based cohort study. CMAJ (2013) 1.79
High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis. Crit Care Med (2010) 1.77
Determination of neurologic prognosis and clinical decision making in adult patients with severe traumatic brain injury: a survey of Canadian intensivists, neurosurgeons, and neurologists. Crit Care Med (2013) 1.72
Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study. CMAJ (2011) 1.72
Negative-pressure ventilation: better oxygenation and less lung injury. Am J Respir Crit Care Med (2007) 1.71
Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. Reg Anesth Pain Med (2010) 1.67
Lung development and susceptibility to ventilator-induced lung injury. Am J Respir Crit Care Med (2005) 1.62
Adaptive behavior, functional outcomes, and quality of life outcomes of children requiring urgent ICU admission. Pediatr Crit Care Med (2013) 1.58
Pulmonary atelectasis: a pathogenic perioperative entity. Anesthesiology (2005) 1.57
Pay for performance in the intensive care unit--opportunity or threat? Crit Care Med (2009) 1.55
Knowledge translation interventions for critically ill patients: a systematic review*. Crit Care Med (2013) 1.53
Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med (2011) 1.52
Improving use of targeted temperature management after out-of-hospital cardiac arrest: a stepped wedge cluster randomized controlled trial. Crit Care Med (2015) 1.52
Glucose in the ICU--evidence, guidelines, and outcomes. N Engl J Med (2012) 1.52
Emergency airway management: competence versus expertise? Anesthesiology (2008) 1.49
Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med (2013) 1.48
Dissociation of inflammatory mediators and function: experimental lung injury in nonpulmonary sepsis. Crit Care Med (2013) 1.48
Scarcity: the context of rationing in an Ontario ICU. Crit Care Med (2013) 1.47
Continuous negative abdominal distension augments recruitment of atelectatic lung. Crit Care Med (2012) 1.46
Mechanical ventilation induces neutrophil extracellular trap formation. Anesthesiology (2015) 1.44
Targeted temperature management processes and outcomes after out-of-hospital cardiac arrest: an observational cohort study*. Crit Care Med (2014) 1.43
Percutaneous dilatational tracheostomy: mostly safe, but do benefits outweigh risks? Crit Care (2014) 1.43
Economic evaluation of decompressive craniectomy versus barbiturate coma for refractory intracranial hypertension following traumatic brain injury. Crit Care Med (2014) 1.42
Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU. Pediatr Crit Care Med (2016) 1.40
Outcomes of interfacility critical care adult patient transport: a systematic review. Crit Care (2006) 1.40
Sodium bicarbonate use in shock and cardiac arrest: attitudes of pediatric acute care physicians. Crit Care Med (2013) 1.40
The use of wireless e-mail to improve healthcare team communication. J Am Med Inform Assoc (2009) 1.39
Learning in patient-based education sessions: a prospective evaluation. Pediatr Crit Care Med (2008) 1.39
Airway management in the lateral position: a randomized controlled trial. Anesth Analg (2005) 1.37
Bench-to-bedside review: carbon dioxide. Crit Care (2010) 1.29
Quantifying the volume of documented clinical information in critical illness. J Crit Care (2007) 1.24
The accuracy of administrative data for identifying the presence and timing of admission to intensive care units in a Canadian province. Med Care (2012) 1.22
Tracheostomy timing in traumatic brain injury: a propensity-matched cohort study. J Trauma Acute Care Surg (2014) 1.22
Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med (2003) 1.20
An official American Thoracic Society policy statement: pay-for-performance in pulmonary, critical care, and sleep medicine. Am J Respir Crit Care Med (2010) 1.20
Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med (2007) 1.20
Hypothermia therapy after pediatric cardiac arrest. Circulation (2009) 1.19
Critical care trainees' career goals and needs: A Canadian survey. Can Respir J (2014) 1.18
Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11
Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat. Am J Physiol Lung Cell Mol Physiol (2006) 1.11
Routine chest x-rays in intensive care units: a systematic review and meta-analysis. Crit Care (2012) 1.11
Predictors of adopting therapeutic hypothermia for post-cardiac arrest patients among Canadian emergency and critical care physicians. Resuscitation (2009) 1.11
Permissive hypercapnia--role in protective lung ventilatory strategies. Intensive Care Med (2004) 1.10
A cross-sectional survey of levels of care and response mechanisms for evolving critical illness in hospitalized children. Pediatrics (2007) 1.09
Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. Am J Physiol Lung Cell Mol Physiol (2007) 1.06
High tidal volume ventilation causes different inflammatory responses in newborn versus adult lung. Am J Respir Crit Care Med (2004) 1.04
Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care (2013) 1.03
Lung-derived soluble mediators are pathogenic in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2011) 1.03
Spontaneous effort causes occult pendelluft during mechanical ventilation. Am J Respir Crit Care Med (2013) 1.02
A systematic review of RIFLE criteria in children, and its application and association with measures of mortality and morbidity. Kidney Int (2012) 1.02
Intracranial pressure monitoring in severe traumatic brain injury: results from the American College of Surgeons Trauma Quality Improvement Program. J Neurotrauma (2013) 0.99
Effects of therapeutic hypercapnia on mesenteric ischemia-reperfusion injury. Am J Respir Crit Care Med (2003) 0.99
Predicting neurologic outcome after targeted temperature management for cardiac arrest: systematic review and meta-analysis. Crit Care Med (2014) 0.98
Continuous positive airway pressure causes lung injury in a model of sepsis. Am J Physiol Lung Cell Mol Physiol (2005) 0.98
An official multi-society statement: the role of clinical research results in the practice of critical care medicine. Am J Respir Crit Care Med (2012) 0.97
Emergency department length of stay for patients requiring mechanical ventilation: a prospective observational study. Scand J Trauma Resusc Emerg Med (2012) 0.97
Delinking resident duty hours from patient safety. BMC Med Educ (2014) 0.96
Atelectasis in the perioperative patient. Curr Opin Anaesthesiol (2007) 0.96
Early growth response-1 worsens ventilator-induced lung injury by up-regulating prostanoid synthesis. Am J Respir Crit Care Med (2010) 0.95
Measuring diaphragm thickness with ultrasound in mechanically ventilated patients: feasibility, reproducibility and validity. Intensive Care Med (2015) 0.95
Early growth response factor-1 in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2007) 0.95
CrossTalk proposal: there is added benefit to providing permissive hypercapnia in the treatment of ARDS. J Physiol (2013) 0.93
Hypercapnic acidosis in ventilator-induced lung injury. Intensive Care Med (2010) 0.92
Prospective evaluation of residents on call: before and after duty-hour reduction. Pediatrics (2011) 0.91
Therapeutic hypercapnia is not protective in the in vivo surfactant-depleted rabbit lung. Pediatr Res (2003) 0.91
Oxygen attenuates atelectasis-induced injury in the in vivo rat lung. Anesthesiology (2005) 0.89
Drug formulations that require less than 0.1 mL of stock solution to prepare doses for infants and children. CMAJ (2011) 0.88
Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats. Am J Physiol Lung Cell Mol Physiol (2009) 0.88
Documentation of pediatric drug safety in manufacturers' product monographs: a cross-sectional evaluation of the canadian compendium of pharmaceuticals and specialities. Paediatr Drugs (2008) 0.88
Use of milrinone in critically ill children. Can J Hosp Pharm (2010) 0.87
Epinephrine increases mortality after brief asphyxial cardiac arrest in an in vivo rat model. Anesth Analg (2006) 0.87
Hypercapnia increases cerebral tissue oxygen tension in anesthetized rats. Can J Anaesth (2003) 0.86
Lost in (knowledge) translation: "All breakthrough, no follow through"? Crit Care Med (2008) 0.86
Do soluble mediators cause ventilator-induced lung injury and multi-organ failure? Intensive Care Med (2010) 0.86
Variation of arterial and central venous catheter use in United States intensive care units. Anesthesiology (2014) 0.86
Prolonged mechanical ventilation induces cell cycle arrest in newborn rat lung. PLoS One (2011) 0.85
Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care: The WikiTrauma Interrupted Time Series Protocol. JMIR Res Protoc (2015) 0.85
Prevalence and indications for video recording in the health care setting in North American and British paediatric hospitals. Paediatr Child Health (2011) 0.85
Surrogate decision makers' attitudes towards research decision making for critically ill patients. Intensive Care Med (2012) 0.85