Published in Neurobiol Aging on October 11, 2005
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Brain structure and obesity. Hum Brain Mapp (2010) 3.04
Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathol (2008) 2.44
Longitudinal examination of obesity and cognitive function: results from the Baltimore longitudinal study of aging. Neuroepidemiology (2010) 2.39
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A (2010) 2.12
Body mass index and magnetic resonance markers of brain integrity in adults. Ann Neurol (2008) 1.88
Cognitive impairment following high fat diet consumption is associated with brain inflammation. J Neuroimmunol (2009) 1.82
Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet. Neurobiol Dis (2009) 1.80
Body mass index over the adult life course and cognition in late midlife: the Whitehall II Cohort Study. Am J Clin Nutr (2008) 1.65
Associations between body mass index and the prevalence of low micronutrient levels among US adults. MedGenMed (2006) 1.63
Shared brain vulnerabilities open the way for nonsubstance addictions: carving addiction at a new joint? Ann N Y Acad Sci (2010) 1.46
Insulin, Central Dopamine D2 Receptors, and Monetary Reward Discounting in Obesity. PLoS One (2015) 1.44
Chronic cigarette smoking: implications for neurocognition and brain neurobiology. Int J Environ Res Public Health (2010) 1.36
Postmenopausal hormone therapy and subclinical cerebrovascular disease: the WHIMS-MRI Study. Neurology (2009) 1.32
Obesity and vulnerability of the CNS. Biochim Biophys Acta (2008) 1.29
Total and regional adiposity and cognitive change in older adults: The Health, Aging and Body Composition (ABC) study. Arch Neurol (2009) 1.26
Saturated long-chain fatty acids activate inflammatory signaling in astrocytes. J Neurochem (2012) 1.21
Patients with Complex Chronic Diseases: perspectives on supporting self-management. J Gen Intern Med (2007) 1.20
Being overweight in midlife is associated with lower cognitive ability and steeper cognitive decline in late life. J Gerontol A Biol Sci Med Sci (2009) 1.19
Obesity phenotypes in midlife and cognition in early old age: the Whitehall II cohort study. Neurology (2012) 1.14
Metabolic syndrome and cognitive function in healthy middle-aged and older adults without diabetes. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn (2008) 1.13
A look inside the diabetic brain: Contributors to diabetes-induced brain aging. Biochim Biophys Acta (2008) 1.12
BMI and neuronal integrity in healthy, cognitively normal elderly: a proton magnetic resonance spectroscopy study. Obesity (Silver Spring) (2009) 1.11
The procognitive effects of leptin in the brain and their clinical implications. Int J Clin Pract (2010) 1.08
Short-term longitudinal trends in cognitive performance in older adults with type 2 diabetes. J Clin Exp Neuropsychol (2009) 1.07
The emerging role of dietary fructose in obesity and cognitive decline. Nutr J (2013) 1.05
Vascularization pattern after ischemic stroke is different in control versus diabetic rats: relevance to stroke recovery. Stroke (2013) 1.05
Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study. Int J Obes (Lond) (2012) 1.04
Obesity and cognitive decline: role of inflammation and vascular changes. Front Neurosci (2014) 1.04
C-reactive protein is linked to lower cognitive performance in overweight and obese women. Inflammation (2008) 1.00
Cardiovascular health and cognitive function: the Maine-Syracuse Longitudinal Study. PLoS One (2014) 0.99
NOX2 deficiency attenuates markers of adiposopathy and brain injury induced by high-fat diet. Am J Physiol Endocrinol Metab (2012) 0.98
NOX activity in brain aging: exacerbation by high fat diet. Free Radic Biol Med (2010) 0.97
Body mass index across midlife and cognitive change in late life. Int J Obes (Lond) (2012) 0.96
Intersection between metabolic dysfunction, high fat diet consumption, and brain aging. J Neurochem (2010) 0.96
Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice. Psychoneuroendocrinology (2013) 0.94
Breakfast and cognition: sixteen effects in nine populations, no single recipe. Front Hum Neurosci (2013) 0.93
Overweight in midlife is related to lower cognitive function 30 years later: a prospective study with longitudinal assessments. Dement Geriatr Cogn Disord (2010) 0.93
Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. Physiol Behav (2010) 0.93
Immune aging, dysmetabolism, and inflammation in neurological diseases. Front Neurosci (2015) 0.92
Weight change and cognitive function: findings from the Women's Health Initiative Study of Cognitive Aging. Obesity (Silver Spring) (2011) 0.92
Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice. Antiviral Res (2010) 0.91
Obesity/hyperleptinemic phenotype impairs structural and functional plasticity in the rat hippocampus. Physiol Behav (2011) 0.90
The metabolic syndrome and cognitive decline in the Atherosclerosis Risk in Communities study (ARIC). Dement Geriatr Cogn Disord (2014) 0.88
Impact of common KIBRA allele on human cognitive functions. Neuropsychopharmacology (2011) 0.88
Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease. Sci Rep (2016) 0.87
Memory decline and depressive symptoms in a nationally representative sample of older adults: the Health and Retirement Study (1998-2004). Dement Geriatr Cogn Disord (2008) 0.87
Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy. Int J Obes (Lond) (2013) 0.87
Estrogens, Neuroinflammation, and Neurodegeneration. Endocr Rev (2016) 0.87
The Use of Multiple Correspondence Analysis to Explore Associations between Categories of Qualitative Variables in Healthy Ageing. J Aging Res (2013) 0.86
Common risk factors for changes in body weight and psychological well-being in Japanese male middle-aged workers. Environ Health Prev Med (2009) 0.85
Human cognitive function and the obesogenic environment. Physiol Behav (2014) 0.85
Long-term dietary intervention trials: critical issues and challenges. Trials (2012) 0.84
Oxymatrine attenuates diabetes-associated cognitive deficits in rats. Acta Pharmacol Sin (2014) 0.84
Obesity, smoking, and frontal brain dysfunction. Am J Addict (2010) 0.84
The impact of obesity and exercise on cognitive aging. Front Aging Neurosci (2013) 0.84
Shared Neuropathological Characteristics of Obesity, Type 2 Diabetes and Alzheimer's Disease: Impacts on Cognitive Decline. Nutrients (2015) 0.83
Chrysin ameliorates diabetes-associated cognitive deficits in Wistar rats. Neurol Sci (2014) 0.82
The impact of vascular comorbidities on qualitative error analysis of executive impairment in Alzheimer's disease. J Int Neuropsychol Soc (2009) 0.82
Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints. Am J Geriatr Psychiatry (2016) 0.81
Adiposity and cognitive decline in the cardiovascular health study. Neuroepidemiology (2013) 0.81
Brain injury caused by HIV protease inhibitors: role of lipodystrophy and insulin resistance. Antiviral Res (2012) 0.81
Cognitive performance of Göttingen minipigs is affected by diet in a spatial hole-board discrimination test. PLoS One (2013) 0.80
Relation between dairy food intake and cognitive function: The Maine-Syracuse Longitudinal Study. Int Dairy J (2012) 0.80
Obesity and Aging: Consequences for Cognition, Brain Structure, and Brain Function. Psychosom Med (2015) 0.80
Cardio-metabolic risk factors and cortical thickness in a neurologically healthy male population: Results from the psychological, social and biological determinants of ill health (pSoBid) study. Neuroimage Clin (2013) 0.80
Relationship between Systemic and Cerebral Vascular Disease and Brain Structure Integrity in Normal Elderly Individuals. J Alzheimers Dis (2015) 0.80
Obesity in elderly subjects: in sheep's clothing perhaps, but still a wolf! Diabetes Care (2009) 0.79
Alzheimer's disease promotion by obesity: induced mechanisms-molecular links and perspectives. Curr Gerontol Geriatr Res (2012) 0.79
Can bariatric surgery reduce risk of Alzheimer's disease? Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.78
Performance in neurocognitive tasks in obese patients. Does somatic comorbidity matter? Front Psychiatry (2013) 0.77
Association of body mass index and waist circumference with successful aging. Obesity (Silver Spring) (2013) 0.77
Relationship between adiposity and cognitive performance in 9-10-year-old children in South India. Arch Dis Child (2013) 0.77
Blood-brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice. J Cereb Blood Flow Metab (2016) 0.77
Western Diet Chow Consumption in Rats Induces Striatal Neuronal Activation While Reducing Dopamine Levels without Affecting Spatial Memory in the Radial Arm Maze. Front Behav Neurosci (2017) 0.77
A population-based study of the association between Trypanosoma cruzi infection and cognitive impairment in old age (the Bambuí Study). Neuroepidemiology (2008) 0.77
Early life overfeeding impairs spatial memory performance by reducing microglial sensitivity to learning. J Neuroinflammation (2016) 0.76
Advanced glycation end product-induced astrocytic differentiation of cultured neurospheres through inhibition of Notch-Hes1 pathway-mediated neurogenesis. Int J Mol Sci (2013) 0.76
National Economic Development Status May Affect the Association between Central Adiposity and Cognition in Older Adults. PLoS One (2016) 0.75
Metabolism-Centric Overview of the Pathogenesis of Alzheimer's Disease. Yonsei Med J (2017) 0.75
Thidoredxin-2 overexpression fails to rescue chronic high calorie diet induced hippocampal dysfunction. Exp Neurol (2015) 0.75
Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer's Disease. J Alzheimers Dis (2016) 0.75
Role of Educational Status in Explaining the Association between Body Mass Index and Cognitive Function. Medicine (Baltimore) (2016) 0.75
Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease. Neurobiol Dis (2017) 0.75
Paternal physical exercise improves spatial learning ability by enhancing hippocampal neuroplasticity in male pups born from obese maternal rats. J Exerc Rehabil (2017) 0.75
Relationship Between Obesity, Alzheimer's Disease, and Parkinson's Disease: an Astrocentric View. Mol Neurobiol (2016) 0.75
Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med (2008) 57.29
General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation (2008) 26.42
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat Med (2010) 14.49
Vitamin D deficiency and risk of cardiovascular disease. Circulation (2008) 13.39
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation (2007) 12.79
Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation. Stat Med (2004) 11.46
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med (2002) 11.20
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation (2013) 10.24
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol (2007) 9.90
Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med (2008) 9.68
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Stenting and medical therapy for atherosclerotic renal-artery stenosis. N Engl J Med (2013) 8.91
2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 8.90
Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation (2004) 8.80
Incidence of diabetes in youth in the United States. JAMA (2007) 8.70
Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study. Arch Intern Med (2007) 8.59
Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation (2005) 8.54
Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation (2002) 8.49
Application of new cholesterol guidelines to a population-based sample. N Engl J Med (2014) 8.22
Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet (2009) 7.27
The burden of diabetes mellitus among US youth: prevalence estimates from the SEARCH for Diabetes in Youth Study. Pediatrics (2006) 7.19
Plasma natriuretic peptide levels and the risk of cardiovascular events and death. N Engl J Med (2004) 7.12
Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study. Am J Respir Crit Care Med (2010) 7.03
Clinical utility of different lipid measures for prediction of coronary heart disease in men and women. JAMA (2007) 6.95
Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med (2002) 6.92
Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study. JAMA (2002) 6.84
Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study. Circulation (2003) 6.83
Obesity and the risk of new-onset atrial fibrillation. JAMA (2004) 6.73
Presentation of multivariate data for clinical use: The Framingham Study risk score functions. Stat Med (2004) 6.42
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation (2007) 6.34
Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community. Arch Intern Med (2007) 6.29
Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age. Circulation (2006) 5.97
Carotid-wall intima-media thickness and cardiovascular events. N Engl J Med (2011) 5.94
Measures of brain morphology and infarction in the framingham heart study: establishing what is normal. Neurobiol Aging (2005) 5.84
A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Med Genet (2007) 5.64
Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study. JAMA (2004) 5.34
Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J Clin Endocrinol Metab (2006) 5.33
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02
Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trial. JAMA (2006) 4.90
Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring. JAMA (2004) 4.85
Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes. JAMA (2013) 4.81
A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study. JAMA (2003) 4.77
Trends in cardiovascular complications of diabetes. JAMA (2004) 4.74
The lifetime risk of stroke: estimates from the Framingham Study. Stroke (2006) 4.68
Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring. JAMA (2004) 4.63
Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample. Arch Intern Med (2008) 4.63
Predicting the 30-year risk of cardiovascular disease: the framingham heart study. Circulation (2009) 4.62
Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis. Ann Intern Med (2015) 4.62
A risk score for predicting near-term incidence of hypertension: the Framingham Heart Study. Ann Intern Med (2008) 4.61
Stroke risk profile predicts white matter hyperintensity volume: the Framingham Study. Stroke (2004) 4.56
On the C-statistics for evaluating overall adequacy of risk prediction procedures with censored survival data. Stat Med (2011) 4.34
Estimating treatment effects using observational data. JAMA (2007) 4.12
Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study. Circulation (2003) 4.09
Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study. Circulation (2005) 4.08
Non-inferiority trials: design concepts and issues - the encounters of academic consultants in statistics. Stat Med (2003) 4.07
Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Am J Hum Genet (2002) 4.07
Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study. Circulation (2007) 3.99
Fasting and postchallenge glycemia and cardiovascular disease risk: the Framingham Offspring Study. Diabetes Care (2002) 3.96
Lipid-related markers and cardiovascular disease prediction. JAMA (2012) 3.91
Depressive symptoms and risk of stroke: the Framingham Study. Stroke (2006) 3.80
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: the Framingham Offspring Study. Stroke (2010) 3.75
Disparities in HbA1c levels between African-American and non-Hispanic white adults with diabetes: a meta-analysis. Diabetes Care (2006) 3.67
Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA (2009) 3.62
Statistical methods for assessment of added usefulness of new biomarkers. Clin Chem Lab Med (2010) 3.57
Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. Eur Heart J (2009) 3.54
Dementia after stroke: the Framingham Study. Stroke (2004) 3.53
Long-term trends in the incidence of heart failure after myocardial infarction. Circulation (2008) 3.52
Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension (2004) 3.51
Trends in incidence, lifetime risk, severity, and 30-day mortality of stroke over the past 50 years. JAMA (2006) 3.50
Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study. Arterioscler Thromb Vasc Biol (2006) 3.48
Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation (2006) 3.41
Neck circumference as a novel measure of cardiometabolic risk: the Framingham Heart study. J Clin Endocrinol Metab (2010) 3.39
Effect of aging on A1C levels in individuals without diabetes: evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001-2004. Diabetes Care (2008) 3.33
C-reactive protein and risk of cardiovascular disease in men and women from the Framingham Heart Study. Arch Intern Med (2005) 3.31
C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation (2004) 3.25