Published in Biochemistry on October 25, 2005
Probing protein structure by amino acid-specific covalent labeling and mass spectrometry. Mass Spectrom Rev (2009) 1.86
HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes. Nat Immunol (2006) 1.41
Protein surface mapping using diethylpyrocarbonate with mass spectrometric detection. Anal Chem (2008) 1.20
Model for the peptide-free conformation of class II MHC proteins. PLoS One (2008) 1.17
Conformational variation in structures of classical and non-classical MHCII proteins and functional implications. Immunol Rev (2012) 1.00
The convergent roles of tapasin and HLA-DM in antigen presentation. Trends Immunol (2008) 0.99
Cross-talk between the catalytic core and the regulatory domain in cystathionine β-synthase: study by differential covalent labeling and computational modeling. Biochemistry (2010) 0.94
Characterization of structural features controlling the receptiveness of empty class II MHC molecules. PLoS One (2011) 0.90
Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection. Immunol Res (2010) 0.90
Mass spectrometric mapping of fibrinogen conformations at poly(ethylene terephthalate) interfaces. Biomaterials (2007) 0.86
Double-stranded RNA binding by the human cytomegalovirus PKR antagonist TRS1. Virology (2013) 0.85
Differential geometric analysis of alterations in MH α-helices. J Comput Chem (2013) 0.85
Development of indole chemistry to label tryptophan residues in protein for determination of tryptophan surface accessibility. Protein Sci (2007) 0.84
For many but not for all: how the conformational flexibility of the peptide/MHCII complex shapes epitope selection. Immunol Res (2013) 0.80
Probing conformational changes in human DNA topoisomerase IIα by pulsed alkylation mass spectrometry. J Biol Chem (2012) 0.80
HLA-DM: arbiter conformationis. Immunology (2013) 0.78
Boosting immune response with the invariant chain segments via association with non-peptide binding region of major histocompatibility complex class II molecules. BMC Immunol (2012) 0.77
Structural characterization of the conformational change in calbindin-D28k upon calcium binding using differential surface modification analyzed by mass spectrometry. Biochemistry (2009) 0.77
Structural Insights Into HLA-DM Mediated MHC II Peptide Exchange. Curr Top Biochem Res (2011) 0.76
Thermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal. Front Immunol (2013) 0.75
Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation. Front Immunol (2017) 0.75
Modeling Functional Motions of Biological Systems by Customized Natural Moves. Biophys J (2016) 0.75
Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat Chem Biol (2007) 2.04
A role for differential variable gene pairing in creating T cell receptors specific for unique major histocompatibility ligands. Immunity (2011) 2.00
Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism. J Immunol (2005) 1.98
Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J Exp Med (2009) 1.73
Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits. Biochemistry (2006) 1.68
Noble metals strip peptides from class II MHC proteins. Nat Chem Biol (2006) 1.53
Class II major histocompatibility complex tetramer staining: progress, problems, and prospects. Immunology (2008) 1.47
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat Struct Mol Biol (2011) 1.42
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. Nat Struct Mol Biol (2012) 1.25
Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange. Proc Natl Acad Sci U S A (2011) 1.23
HLA-restricted epitope identification and detection of functional T cell responses by using MHC-peptide and costimulatory microarrays. Proc Natl Acad Sci U S A (2005) 1.21
Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection. PLoS Pathog (2007) 1.20
The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells. J Immunol (2007) 1.18
Model for the peptide-free conformation of class II MHC proteins. PLoS One (2008) 1.17
Enhanced catalytic action of HLA-DM on the exchange of peptides lacking backbone hydrogen bonds between their N-terminal region and the MHC class II alpha-chain. J Immunol (2004) 1.15
Labeling antigen-specific CD4(+) T cells with class II MHC oligomers. J Immunol Methods (2002) 1.11
Human CD4+ T cell response to human herpesvirus 6. J Virol (2012) 1.10
A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition. Proc Natl Acad Sci U S A (2004) 1.09
Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site. J Immunol (2002) 1.09
CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement. J Immunol (2006) 1.06
Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules. Proc Natl Acad Sci U S A (2002) 1.06
Tetherin/BST-2 antagonism by Nef depends on a direct physical interaction between Nef and tetherin, and on clathrin-mediated endocytosis. PLoS Pathog (2013) 1.05
Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation. J Immunol (2002) 1.04
An expanded self-antigen peptidome is carried by the human lymph as compared to the plasma. PLoS One (2010) 1.02
A polymorphic pocket at the P10 position contributes to peptide binding specificity in class II MHC proteins. Chem Biol (2004) 1.01
Conformational variation in structures of classical and non-classical MHCII proteins and functional implications. Immunol Rev (2012) 1.00
Conformational variation of surface class II MHC proteins during myeloid dendritic cell differentiation accompanies structural changes in lysosomal MIIC. J Immunol (2005) 0.99
The intrinsically disordered cytoplasmic domain of the T cell receptor zeta chain binds to the nef protein of simian immunodeficiency virus without a disorder-to-order transition. Biochemistry (2008) 0.97
Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis. Proc Natl Acad Sci U S A (2012) 0.97
Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding. J Biol Chem (2004) 0.97
HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives. J Immunol (2012) 0.97
Antigenic peptide trimming by ER aminopeptidases--insights from structural studies. Mol Immunol (2013) 0.97
Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses. J Immunol (2007) 0.94
Crystallographic structure of the human leukocyte antigen DRA, DRB3*0101: models of a directional alloimmune response and autoimmunity. J Mol Biol (2007) 0.93
Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4+ T cells from a vaccinated donor. J Proteome Res (2008) 0.92
GMCSF in the absence of other cytokines sustains human dendritic cell precursors with T cell regulatory activity and capacity to differentiate into functional dendritic cells. Immunol Lett (2007) 0.90
Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers. Sci Rep (2012) 0.90
Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides. Proc Natl Acad Sci U S A (2012) 0.89
Structure induction of the T-cell receptor zeta-chain upon lipid binding investigated by NMR spectroscopy. Chembiochem (2007) 0.89
Pseudo-merohedral twinning and noncrystallographic symmetry in orthorhombic crystals of SIVmac239 Nef core domain bound to different-length TCRzeta fragments. Acta Crystallogr D Biol Crystallogr (2010) 0.89
Major histocompatibility complex and T cell interactions of a universal T cell epitope from Plasmodium falciparum circumsporozoite protein. J Biol Chem (2006) 0.88
Antigen-specific T cell phenotyping microarrays using grating coupled surface plasmon resonance imaging and surface plasmon coupled emission. Biosens Bioelectron (2011) 0.87
Examination of the highly diverse CD4(+) T-cell repertoire directed against an influenza peptide: a step towards TCR proteomics. Immunogenetics (2002) 0.86
Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells. J Immunol (2013) 0.86
Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1. J Biol Chem (2003) 0.85
Induced fit of an epitope peptide to a monoclonal antibody probed with a novel parallel surface plasmon resonance assay. J Biol Chem (2004) 0.84
Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope. Mol Immunol (2005) 0.84
Peptide-MHC cellular microarray with innovative data analysis system for simultaneously detecting multiple CD4 T-cell responses. PLoS One (2010) 0.83
Bi-specific MHC heterodimers for characterization of cross-reactive T cells. J Biol Chem (2010) 0.83
CD4+ T cells provide intermolecular help to generate robust antibody responses in vaccinia virus-vaccinated humans. J Immunol (2013) 0.82
Carrying yourself: self antigen composition of the lymphatic fluid. Lymphat Res Biol (2013) 0.78
Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization. Curr Protoc Immunol (2014) 0.78
HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange. Front Immunol (2013) 0.77
Pillars article: three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature. 1993. 364: 33-39. J Immunol (2015) 0.75
Response to Garcia et al. Immunity (2012) 0.75
Dihydrolipoic acid as an effective cofactor for peptide methionine sulfoxide reductase in enzymatic repair of oxidative damage to both lipid-free and lipid-bound apolipoprotein a-I. Antioxid Redox Signal (2002) 0.75