Published in Am J Physiol Cell Physiol on October 19, 2005
Structural basis of protein kinase C isoform function. Physiol Rev (2008) 4.00
Coincident regulation of PKCdelta in human platelets by phosphorylation of Tyr311 and Tyr565 and phospholipase C signalling. Biochem J (2007) 0.91
Multiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311. J Invest Dermatol (2007) 0.82
Regulation of protein kinase C delta downregulation by protein kinase C epsilon and mammalian target of rapamycin complex 2. Cell Signal (2009) 0.80
No specific subcellular localization of protein kinase C is required for cytotoxic T cell granule exocytosis. J Biol Chem (2009) 0.79
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell (2002) 4.35
Caveolar localization dictates physiologic signaling of beta 2-adrenoceptors in neonatal cardiac myocytes. J Biol Chem (2002) 2.06
Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms. J Biol Chem (2004) 1.51
Neuropeptide Y is an essential in vivo developmental regulator of cardiac ICa,L. Circ Res (2003) 1.47
Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I. J Biol Chem (2008) 1.46
Stimulus-specific differences in protein kinase C delta localization and activation mechanisms in cardiomyocytes. J Biol Chem (2004) 1.43
Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. Circulation (2003) 1.36
Cross-regulation of novel protein kinase C (PKC) isoform function in cardiomyocytes. Role of PKC epsilon in activation loop phosphorylations and PKC delta in hydrophobic motif phosphorylations. J Biol Chem (2003) 1.35
Protein kinase D links Gq-coupled receptors to cAMP response element-binding protein (CREB)-Ser133 phosphorylation in the heart. J Biol Chem (2008) 1.29
Protein kinase D1 autophosphorylation via distinct mechanisms at Ser744/Ser748 and Ser916. J Biol Chem (2008) 1.24
Protein kinase C isoform-selective signals that lead to cardiac hypertrophy and the progression of heart failure. Mol Cell Biochem (2003) 1.20
p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes. Circ Res (2009) 1.12
Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism. J Biol Chem (2003) 1.10
Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation. Am J Physiol Endocrinol Metab (2010) 1.09
Protein kinase Cepsilon (PKCepsilon) and Src control PKCdelta activation loop phosphorylation in cardiomyocytes. J Biol Chem (2007) 1.07
Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin. J Biol Chem (2004) 1.06
Developmental changes in beta2-adrenergic receptor signaling in ventricular myocytes: the role of Gi proteins and caveolae microdomains. Mol Pharmacol (2003) 1.05
Mechanisms of protease-activated receptor-4 actions in cardiomyocytes. Role of Src tyrosine kinase. J Biol Chem (2003) 0.99
Alpha1-adrenergic receptors activate AKT via a Pyk2/PDK-1 pathway that is tonically inhibited by novel protein kinase C isoforms in cardiomyocytes. Circ Res (2006) 0.98
Dual actions of the Galpha(q) agonist Pasteurella multocida toxin to promote cardiomyocyte hypertrophy and enhance apoptosis susceptibility. Circ Res (2002) 0.98
Reactive oxygen species decrease cAMP response element binding protein expression in cardiomyocytes via a protein kinase D1-dependent mechanism that does not require Ser133 phosphorylation. Mol Pharmacol (2009) 0.97
Phorbol 12-myristate 13-acetate-dependent protein kinase C delta-Tyr311 phosphorylation in cardiomyocyte caveolae. J Biol Chem (2008) 0.93
Caveolae-associated proteins in cardiomyocytes: caveolin-2 expression and interactions with caveolin-3. Am J Physiol Heart Circ Physiol (2003) 0.93
Protein kinase D isoforms are activated in an agonist-specific manner in cardiomyocytes. J Biol Chem (2010) 0.92
Distinct signaling functions for Shc isoforms in the heart. J Biol Chem (2006) 0.92
Redox signaling and cardiac sarcomeres. J Biol Chem (2011) 0.88
Regulatory autophosphorylation sites on protein kinase C-delta at threonine-141 and threonine-295. Biochemistry (2009) 0.86
Cleavage of protein kinase D after acute hypoinsulinemia prevents excessive lipoprotein lipase-mediated cardiac triglyceride accumulation. Diabetes (2009) 0.85
Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis. Circ Res (2007) 0.85
Beta 2-adrenergic receptor signaling acts via NO release to mediate ACh-induced activation of ATP-sensitive K+ current in cat atrial myocytes. J Gen Physiol (2002) 0.84
Protein kinase C-{delta} regulates the subcellular localization of Shc in H2O2-treated cardiomyocytes. Am J Physiol Cell Physiol (2010) 0.84
Raf-1: a novel cardiac troponin T kinase. J Muscle Res Cell Motil (2009) 0.82
S49G and R389G polymorphisms of the β₁-adrenergic receptor influence signaling via the cAMP-PKA and ERK pathways. Physiol Genomics (2013) 0.82
G protein betagamma dimer expression in cardiomyocytes: developmental acquisition of Gbeta3. Biochem Biophys Res Commun (2008) 0.80
Age-dependent differences in the inhibition of HCN2 current in rat ventricular myocytes by the tyrosine kinase inhibitor erbstatin. Pflugers Arch (2008) 0.79
Cardiac hypertrophy served with protein kinase Cepsilon: delta isoform substitution available at additional cost. Circ Res (2005) 0.78
Alpha(1)-adrenergic receptor subtype function in cardiomyocytes: lessons from genetic models in mice. J Mol Cell Cardiol (2002) 0.78
Focus on "targeted expression of activated Q227L G(alpha)(s) in vivo". Am J Physiol Cell Physiol (2002) 0.76
Regulatory domain determinants that control PKD1 activity. J Biol Chem (2012) 0.75