Published in J Cell Biol on October 24, 2005
Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci (2008) 4.32
Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J Cell Biol (2007) 3.61
The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy. Dev Cell (2013) 2.24
PDV1 and PDV2 mediate recruitment of the dynamin-related protein ARC5 to the plastid division site. Plant Cell (2006) 2.02
The molecular mechanism and cellular functions of mitochondrial division. Biochim Biophys Acta (2008) 1.67
Structural basis for recruitment of mitochondrial fission complexes by Fis1. Proc Natl Acad Sci U S A (2007) 1.58
Mitochondrial network size scaling in budding yeast. Science (2012) 1.44
Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration. Antioxid Redox Signal (2012) 1.32
Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine. Chem Biol (2010) 1.30
Direct binding of the dynamin-like GTPase, Dnm1, to mitochondrial dynamics protein Fis1 is negatively regulated by the Fis1 N-terminal arm. J Biol Chem (2007) 1.28
Mitochondrial division: molecular machinery and physiological functions. Curr Opin Cell Biol (2011) 1.22
Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J Biol Chem (2013) 1.19
Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes. J Cell Biol (2010) 1.10
Arabidopsis ELONGATED MITOCHONDRIA1 is required for localization of DYNAMIN-RELATED PROTEIN3A to mitochondrial fission sites. Plant Cell (2008) 1.02
Stress-induced nuclear-to-cytoplasmic translocation of cyclin C promotes mitochondrial fission in yeast. Dev Cell (2014) 0.99
Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission. J Cell Biol (2014) 0.94
The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction. Exp Cell Res (2008) 0.93
Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates. Cell Mol Life Sci (2012) 0.93
Mitochondrial Quality Control and Muscle Mass Maintenance. Front Physiol (2016) 0.92
A novel motif in the yeast mitochondrial dynamin Dnm1 is essential for adaptor binding and membrane recruitment. J Cell Biol (2012) 0.83
The mitochondrial fission adaptors Caf4 and Mdv1 are not functionally equivalent. PLoS One (2012) 0.81
Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae. Biochemistry (2009) 0.81
The cytosolic domain of Fis1 binds and reversibly clusters lipid vesicles. PLoS One (2011) 0.80
A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission. J Mol Biol (2012) 0.78
The 1.75 Å resolution structure of fission protein Fis1 from Saccharomyces cerevisiae reveals elusive interactions of the autoinhibitory domain. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.78
Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction. Front Aging Neurosci (2015) 0.78
Plant mitochondrial dynamics and the role of membrane lipids. Plant Signal Behav (2015) 0.77
A Targeted Mutation Identified through pKa Measurements Indicates a Postrecruitment Role for Fis1 in Yeast Mitochondrial Fission. J Biol Chem (2016) 0.76
Removal of a consensus proline is not sufficient to allow tetratricopeptide repeat oligomerization. Protein Sci (2017) 0.75
Protein structure comparison by alignment of distance matrices. J Mol Biol (1993) 34.74
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics (1996) 24.62
5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol (1987) 17.67
Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol (1991) 16.88
Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds. Gene (1995) 13.86
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell (2001) 10.33
Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C. Yeast (1995) 9.80
Genetic applications of yeast transformation with linear and gapped plasmids. Methods Enzymol (1983) 8.96
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell (2004) 7.45
TPR proteins: the versatile helix. Trends Biochem Sci (2003) 7.37
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast. Nat Cell Biol (1999) 6.26
C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol Cell (1999) 6.14
Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu Rev Genet (2005) 6.03
A human dynamin-related protein controls the distribution of mitochondria. J Cell Biol (1998) 6.02
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell (2004) 5.94
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J Cell Biol (2000) 5.86
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J Cell Biol (1999) 5.53
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J Cell Biol (1998) 5.21
Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase. Cell (1997) 5.13
Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed). Nat Biotechnol (2002) 5.07
The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J Cell Biol (1998) 4.72
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol Cell Biol (2003) 4.56
Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division. J Cell Biol (2000) 4.07
DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans. Nature (2005) 3.99
Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae. J Biol Chem (1998) 3.96
hFis1, a novel component of the mammalian mitochondrial fission machinery. J Biol Chem (2003) 3.84
The machinery of mitochondrial inheritance and behavior. Science (1999) 3.82
Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ (2003) 3.75
Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis. Mol Cell (2004) 3.28
Mitochondrial dynamics and division in budding yeast. Trends Cell Biol (2002) 3.15
Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol (1998) 3.11
Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J Cell Sci (2004) 2.78
The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission. J Cell Biol (2002) 2.74
Gag3p, an outer membrane protein required for fission of mitochondrial tubules. J Cell Biol (2000) 2.62
Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol (2003) 2.44
The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria. J Cell Biol (2005) 2.33
Division of mitochondria requires a novel DMN1-interacting protein, Net2p. Mol Biol Cell (2001) 2.17
Constriction and Dnm1p recruitment are distinct processes in mitochondrial fission. Mol Biol Cell (2003) 1.98
The division of endosymbiotic organelles. Science (2003) 1.94
Yeast mitochondrial dynamics: fusion, division, segregation, and shape. Microsc Res Tech (2000) 1.89
The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle. J Mol Biol (2003) 1.70
A dynamin-like protein (ADL2b), rather than FtsZ, is involved in Arabidopsis mitochondrial division. Proc Natl Acad Sci U S A (2002) 1.61
The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria. Mol Biol Cell (2003) 1.59
A fuzzy mitochondrial fusion apparatus comes into focus. Nat Rev Mol Cell Biol (2003) 1.54
Mitochondrial dynamics in mammals. Curr Top Dev Biol (2004) 1.53
Merging mitochondria matters: cellular role and molecular machinery of mitochondrial fusion. EMBO Rep (2002) 1.47
The GTPase effector domain sequence of the Dnm1p GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fission. Mol Biol Cell (2001) 1.46
Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. Proteins (2004) 1.39
A mitochondrial division apparatus takes shape. J Cell Biol (2000) 1.34
Mmm1p spans both the outer and inner mitochondrial membranes and contains distinct domains for targeting and foci formation. J Biol Chem (2003) 1.32
Novel structure of the N terminus in yeast Fis1 correlates with a specialized function in mitochondrial fission. J Biol Chem (2005) 1.27
Mitochondrial membrane fusion. Biochim Biophys Acta (2003) 1.17
Mitochondrial dynamics in filamentous fungi. Fungal Genet Biol (2002) 0.90
Divide et impera: Ca2+ signals, mitochondrial fission and sensitization to apoptosis. Cell Death Differ (2003) 0.86
Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu Rev Genet (2005) 6.03
Moving mitochondria: establishing distribution of an essential organelle. Traffic (2007) 2.44
Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway. J Cell Biol (2004) 2.42
Mitochondrial GFA2 is required for synergid cell death in Arabidopsis. Plant Cell (2002) 1.78
A fuzzy mitochondrial fusion apparatus comes into focus. Nat Rev Mol Cell Biol (2003) 1.54
Dual kidney transplantation: a case-control comparison with single kidney transplantation from standard and expanded criteria donors. Transplantation (2007) 1.43
Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission. Proc Natl Acad Sci U S A (2013) 1.39
Dimeric Dnm1-G385D interacts with Mdv1 on mitochondria and can be stimulated to assemble into fission complexes containing Mdv1 and Fis1. J Biol Chem (2006) 1.37
Multiple pathways influence mitochondrial inheritance in budding yeast. Genetics (2008) 1.32
Mmm1p spans both the outer and inner mitochondrial membranes and contains distinct domains for targeting and foci formation. J Biol Chem (2003) 1.32
Germline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiency. Am J Hum Genet (2013) 1.23
Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast. Proc Natl Acad Sci U S A (2003) 1.21
Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic (2012) 1.21
Importance of mitochondrial dynamics during meiosis and sporulation. Mol Biol Cell (2004) 1.14
Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes. J Cell Biol (2010) 1.10
A mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover. Mol Biol Cell (2009) 1.08
Structure-function analysis of the yeast mitochondrial Rho GTPase, Gem1p: implications for mitochondrial inheritance. J Biol Chem (2010) 1.08
Mitochondrial fusion and function in Charcot-Marie-Tooth type 2A patient fibroblasts with mitofusin 2 mutations. Exp Neurol (2008) 1.07
Wnt pathway inhibitors are strongly down-regulated in pituitary tumors. Endocrinology (2007) 1.07
Dynamin assembly strategies and adaptor proteins in mitochondrial fission. Curr Biol (2013) 1.07
IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients. J Neuropathol Exp Neurol (2007) 1.07
Resistant starches protect against colonic DNA damage and alter microbiota and gene expression in rats fed a Western diet. J Nutr (2012) 1.00
The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast. Mol Biol Cell (2006) 0.99
Development and reproducibility of the bone loading history questionnaire. Med Sci Sports Exerc (2006) 0.98
Clinical evaluation of a wireless intra-vaginal pressure transducer. Int Urogynecol J (2012) 0.98
Sequential requirements for the GTPase domain of the mitofusin Fzo1 and the ubiquitin ligase SCFMdm30 in mitochondrial outer membrane fusion. J Cell Sci (2011) 0.97
Tetratricopeptide repeat proteins Tom70 and Tom71 mediate yeast mitochondrial morphogenesis. EMBO Rep (2007) 0.96
Detection and characterisation of human metapneumovirus from children with acute respiratory symptoms in north-west England, UK. J Clin Virol (2008) 0.92
Activity restrictions after gynecologic surgery: is there evidence? Int Urogynecol J (2013) 0.91
Ugo1p is a multipass transmembrane protein with a single carrier domain required for mitochondrial fusion. Traffic (2007) 0.91
Intermediate-term outcomes with expanded criteria deceased donors in kidney transplantation: a spectrum or specter of quality? Ann Surg (2006) 0.90
More complicated than it looks: the vagaries of calculating intra-abdominal pressure. J Strength Cond Res (2013) 0.89
Identification of patients with RAG mutations previously diagnosed with common variable immunodeficiency disorders. J Clin Immunol (2014) 0.89
Bone mineral density of olympic-level female winter sport athletes. Med Sci Sports Exerc (2004) 0.86
Mitochondrial association, protein phosphorylation, and degradation regulate the availability of the active Rab GTPase Ypt11 for mitochondrial inheritance. Mol Biol Cell (2013) 0.84
A novel motif in the yeast mitochondrial dynamin Dnm1 is essential for adaptor binding and membrane recruitment. J Cell Biol (2012) 0.83
TACI mutation p.Lys154Ter identified in Good Syndrome. Clin Immunol (2012) 0.82
Arabidopsis has two functional orthologs of the yeast V-ATPase assembly factor Vma21p. Traffic (2008) 0.82
Optimal use of older donors and recipients in kidney transplantation. Surgery (2006) 0.81
The mitochondrial fission adaptors Caf4 and Mdv1 are not functionally equivalent. PLoS One (2012) 0.81
Resistant starch alters colonic contractility and expression of related genes in rats fed a Western diet. Dig Dis Sci (2015) 0.80
Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat. BMC Physiol (2013) 0.80
Reanalysis and simulation suggest a phylogenetic microarray does not accurately profile microbial communities. PLoS One (2012) 0.79
Experience with dual kidney transplants from donors at the extremes of age. Surgery (2006) 0.78
Effects of walking speeds and carrying techniques on intra-abdominal pressure in women. Int Urogynecol J (2014) 0.78
Reproducibility of intra-abdominal pressure measured during physical activities via a wireless vaginal transducer. Female Pelvic Med Reconstr Surg (2015) 0.78
"How Hard Could it Be?" A Descriptive Analysis of Errors Made on a Validated Lifetime Physical Activity Questionnaire. J Phys Act Health (2014) 0.75
VarBin, a novel method for classifying true and false positive variants in NGS data. BMC Bioinformatics (2013) 0.75
Predictive Validity of an Adult Physical Activity "Vital Sign" Recorded in Electronic Health Records. J Phys Act Health (2015) 0.75
Kidney and pancreas transplantation at Wake Forest University Baptist Medical Center. Clin Transpl (2003) 0.75
Comparison of the Effects of Seated, Supine, and Walking Interset Rest Strategies on Work Rate. J Strength Cond Res (2016) 0.75
Variables Affecting Intra-abdominal Pressure During Lifting in the Early Postpartum Period. Female Pelvic Med Reconstr Surg (2017) 0.75
High school physical educators' and sport coaches' knowledge of resistance training principles and methods. J Strength Cond Res (2014) 0.75