Published in J Am Soc Nephrol on October 26, 2005
Uric acid and cardiovascular risk. N Engl J Med (2008) 12.20
Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology (2010) 3.73
Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes? Endocr Rev (2009) 2.65
Indoxyl sulfate-induced endothelial dysfunction in patients with chronic kidney disease via an induction of oxidative stress. Clin J Am Soc Nephrol (2010) 2.16
Sugar, uric acid, and the etiology of diabetes and obesity. Diabetes (2013) 2.03
Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes (2011) 1.82
Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids (2008) 1.76
High-normal serum uric acid is associated with impaired glomerular filtration rate in nonproteinuric patients with type 1 diabetes. Clin J Am Soc Nephrol (2008) 1.74
Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells. Am J Physiol Cell Physiol (2008) 1.69
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. Am J Physiol Renal Physiol (2008) 1.68
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver. J Biol Chem (2012) 1.67
Systemic inflammation, metabolic syndrome and progressive renal disease. Nephrol Dial Transplant (2009) 1.63
The relationship between serum uric acid and chronic kidney disease among Appalachian adults. Nephrol Dial Transplant (2010) 1.60
Uric acid and chronic kidney disease: which is chasing which? Nephrol Dial Transplant (2013) 1.55
Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Ann Rheum Dis (2014) 1.54
Association of Uric Acid With Vascular Stiffness in the Framingham Heart Study. Am J Hypertens (2014) 1.48
Uric Acid as a Marker of Mortality and Morbidity in Fabry Disease. PLoS One (2016) 1.39
Uric acid as a pathogenic factor in preeclampsia. Placenta (2008) 1.38
Uric acid, hyperuricemia and vascular diseases. Front Biosci (Landmark Ed) (2012) 1.38
The connection between C-reactive protein and atherosclerosis. Ann Med (2008) 1.29
Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake. Metabolism (2011) 1.27
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver. PLoS One (2012) 1.24
Is the fructose index more relevant with regards to cardiovascular disease than the glycemic index? Eur J Nutr (2007) 1.24
Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society? J Comp Physiol B (2008) 1.23
Potential role of uric acid in metabolic syndrome, hypertension, kidney injury, and cardiovascular diseases: is it time for reappraisal? Curr Hypertens Rep (2013) 1.20
Is hyperuricemia an independent risk factor for new-onset chronic kidney disease?: A systematic review and meta-analysis based on observational cohort studies. BMC Nephrol (2014) 1.19
Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver. Eur J Nutr (2009) 1.12
Uric acid-induced endothelial dysfunction is associated with mitochondrial alterations and decreased intracellular ATP concentrations. Nephron Exp Nephrol (2012) 1.12
Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study. J Rheumatol (2009) 1.11
Uric acid as a mediator of diabetic nephropathy. Semin Nephrol (2011) 1.11
Tumor lysis syndrome: new challenges and recent advances. Adv Chronic Kidney Dis (2014) 1.11
Serum uric acid predicts progression of subclinical coronary atherosclerosis in individuals without renal disease. Diabetes Care (2010) 1.10
Clinical outcome of hyperuricemia in IgA nephropathy: a retrospective cohort study and randomized controlled trial. Kidney Blood Press Res (2011) 1.10
Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study. Curr Diab Rep (2013) 1.09
Review of hyperuricemia as new marker for metabolic syndrome. ISRN Rheumatol (2014) 1.08
Contribution of uric acid to cancer risk, recurrence, and mortality. Clin Transl Med (2012) 1.08
Pathogenesis of essential hypertension: historical paradigms and modern insights. J Hypertens (2008) 1.06
Gout and the risk for incident heart failure and systolic dysfunction. BMJ Open (2012) 1.06
Uric acid: a danger signal from the RNA world that may have a role in the epidemic of obesity, metabolic syndrome, and cardiorenal disease: evolutionary considerations. Semin Nephrol (2011) 1.05
Hyperuricemia and risk of incident hypertension: a systematic review and meta-analysis of observational studies. PLoS One (2014) 1.04
Increased cardiovascular mortality associated with gout: a systematic review and meta-analysis. Eur J Prev Cardiol (2013) 1.02
Sucrose, high-fructose corn syrup, and fructose, their metabolism and potential health effects: what do we really know? Adv Nutr (2013) 1.02
Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayers. Am J Physiol Cell Physiol (2009) 1.00
Are either or both hyperuricemia and xanthine oxidase directly toxic to the vasculature? A critical appraisal. Arthritis Rheum (2012) 1.00
Uric Acid Puzzle: Dual Role as Anti-oxidantand Pro-oxidant. Electrolyte Blood Press (2014) 0.98
The relationship between hyperuricemia and the risk of contrast-induced acute kidney injury after percutaneous coronary intervention in patients with relatively normal serum creatinine. Clinics (Sao Paulo) (2013) 0.98
Uric acid is a risk factor for ischemic stroke and all-cause mortality in the general population: a gender specific analysis from The Tromsø Study. BMC Cardiovasc Disord (2013) 0.97
SLC2A9--a fructose transporter identified as a novel uric acid transporter. Nephrol Dial Transplant (2008) 0.96
Uric acid induces renal inflammation via activating tubular NF-κB signaling pathway. PLoS One (2012) 0.95
Risk factors for peripheral arterial disease among patients with chronic kidney disease. Am J Cardiol (2012) 0.94
Serum uric acid levels are associated with polymorphism in the SAA1 gene in Chinese subjects. PLoS One (2012) 0.94
Interaction of inflammation, hyperuricemia, and the prevalence of hypertension among adults free of metabolic syndrome: NHANES 2009-2010. J Am Heart Assoc (2014) 0.94
The planetary biology of ascorbate and uric acid and their relationship with the epidemic of obesity and cardiovascular disease. Med Hypotheses (2008) 0.94
Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats. Am J Physiol Renal Physiol (2013) 0.93
Serum uric acid level and endothelial dysfunction in patients with nondiabetic chronic kidney disease. Am J Nephrol (2011) 0.92
Hyperuricemia and incident heart failure. Circ Heart Fail (2009) 0.92
Early nephropathy in type 1 diabetes: the importance of early renal function decline. Curr Opin Nephrol Hypertens (2009) 0.92
Potential role of uric Acid as a risk factor for cardiovascular disease. Korean J Intern Med (2010) 0.91
Uric acid promotes apoptosis in human proximal tubule cells by oxidative stress and the activation of NADPH oxidase NOX 4. PLoS One (2014) 0.91
Serum uric acid and 1-h postload glucose in essential hypertension. Diabetes Care (2011) 0.90
Fructose and cardiometabolic disorders: the controversy will, and must, continue. Clinics (Sao Paulo) (2010) 0.90
Combination of captopril and allopurinol retards fructose-induced metabolic syndrome. Am J Nephrol (2009) 0.89
A sensitive and specific liquid chromatography-tandem mass spectrometry method for the determination of intracellular and extracellular uric acid. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.89
C-reactive protein and vein graft disease: evidence for a direct effect on smooth muscle cell phenotype via modulation of PDGF receptor-beta. Am J Physiol Heart Circ Physiol (2008) 0.88
Plasma uric acid levels correlate with inflammation and disease severity in Malian children with Plasmodium falciparum malaria. PLoS One (2012) 0.88
The role of uric acid in kidney fibrosis: experimental evidences for the causal relationship. Biomed Res Int (2014) 0.88
Uric acid and pentraxin-3 levels are independently associated with coronary artery disease risk in patients with stage 2 and 3 kidney disease. Am J Nephrol (2011) 0.88
Uric acid in metabolic syndrome: From an innocent bystander to a central player. Eur J Intern Med (2015) 0.87
Associations Between Hyperuricemia and Chronic Kidney Disease: A Review. Nephrourol Mon (2015) 0.87
Effects of hyperuricemia on renal function of renal transplant recipients: a systematic review and meta-analysis of cohort studies. PLoS One (2012) 0.84
Endothelial health and diversity in the kidney. J Am Soc Nephrol (2006) 0.84
Could uric acid be a modifiable risk factor in subjects with pulmonary hypertension? Med Hypotheses (2010) 0.84
Usefulness of combining serum uric acid and high-sensitivity C-reactive protein for risk stratification of patients with metabolic syndrome in community-dwelling women. Endocrine (2013) 0.83
Perfluoroalkyl chemicals and elevated serum uric acid in US adults. Clin Epidemiol (2011) 0.83
Vascular Function and Uric Acid-Lowering in Stage 3 CKD. J Am Soc Nephrol (2016) 0.83
EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway. Oxid Med Cell Longev (2015) 0.82
Vascular endothelial function is not related to serum uric acid in healthy adults. Am J Hypertens (2012) 0.82
Gene polymorphisms in association with emerging cardiovascular risk markers in adult women. BMC Med Genet (2010) 0.82
Serum urate is not associated with coronary artery calcification: the NHLBI Family Heart Study. J Rheumatol (2010) 0.82
Fructose-containing sugars and cardiovascular disease. Adv Nutr (2015) 0.82
Hyperuricemia and deterioration of renal function in autosomal dominant polycystic kidney disease. BMC Nephrol (2014) 0.82
Serum uric acid level in newly diagnosed essential hypertension in a Nepalese population: a hospital based cross sectional study. Asian Pac J Trop Biomed (2014) 0.82
Role of xanthine oxidoreductase in cardiac nitroso-redox imbalance. Front Biosci (Landmark Ed) (2009) 0.81
Uric acid, hypertension, and chronic kidney disease among Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study. J Clin Hypertens (Greenwich) (2012) 0.81
Could uric acid have a pathogenic role in pre-eclampsia? Nat Rev Nephrol (2010) 0.81
Comparative study of renal protective effects of allopurinol and N-acetyl-cysteine on contrast induced nephropathy in patients undergoing cardiac catheterization. J Clin Diagn Res (2014) 0.81
Hypertension and chronic kidney disease: controversies in pathogenesis and treatment. Minerva Urol Nefrol (2013) 0.81
The mechanisms underlying fructose-induced hypertension: a review. J Hypertens (2015) 0.81
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy. Nephron Exp Nephrol (2011) 0.81
Determinants of vascular function in patients with chronic gout. J Clin Hypertens (Greenwich) (2010) 0.80
Relationship between uric acid and subtle cognitive dysfunction in chronic kidney disease. Am J Nephrol (2011) 0.80
Positive association between perfluoroalkyl chemicals and hyperuricemia in children. Am J Epidemiol (2013) 0.80
Clinical Scenario of the Metabolic Syndrome. Visc Med (2016) 0.80
Health Implications of High-Fructose Intake and Current Research. Adv Nutr (2015) 0.79
The association between serum uric acid and renal damage in a community-based population: the Takahata study. Clin Exp Nephrol (2012) 0.79
Hyperuricemia is independently associated with endothelial dysfunction in postmenopausal women but not in premenopausal women. BMJ Open (2013) 0.79
Oxidative stress in Mexicans with diffuse cutaneous systemic sclerosis. Rheumatol Int (2013) 0.78
Correlation between renal function and common risk factors for chronic kidney disease in a healthy middle-aged population: a prospective observational 2-year study. PLoS One (2014) 0.78
Novel drugs and intervention strategies for the treatment of chronic kidney disease. Br J Clin Pharmacol (2013) 0.78
Hyperuricemia: A non-traditional risk factor for development and progression of chronic kidney disease? Kidney Res Clin Pract (2012) 0.78
Uric acid and cardiovascular risk. N Engl J Med (2008) 12.20
Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial. JAMA (2008) 5.59
Hyperuricemia induces endothelial dysfunction. Kidney Int (2005) 5.36
A causal role for uric acid in fructose-induced metabolic syndrome. Am J Physiol Renal Physiol (2005) 4.95
A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diabetes Care (2006) 4.66
A role for uric acid in the progression of renal disease. J Am Soc Nephrol (2002) 3.77
Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology (2010) 3.73
Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension (2003) 3.39
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol (2002) 3.37
Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J Hepatol (2008) 3.33
Evolving importance of kidney disease: from subspecialty to global health burden. Lancet (2013) 3.30
Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol (2007) 3.08
Anti-obesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat Med (2004) 2.80
IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly. Kidney Int (2005) 2.78
Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress. Am J Physiol Cell Physiol (2007) 2.71
Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells. J Am Soc Nephrol (2009) 2.70
Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. Diabetes Care (2007) 2.62
Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol (2002) 2.51
Uric acid, hominoid evolution, and the pathogenesis of salt-sensitivity. Hypertension (2002) 2.47
Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis. Kidney Int (2010) 2.47
Hyperuricemia in childhood primary hypertension. Hypertension (2003) 2.39
Serum uric acid, inflammation, and nondipping circadian pattern in essential hypertension. J Clin Hypertens (Greenwich) (2012) 2.37
Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP. Diabetes (2007) 2.34
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. Nat Commun (2013) 2.29
Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding. Am J Physiol Regul Integr Comp Physiol (2008) 2.28
Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome. Nat Clin Pract Nephrol (2005) 2.24
Thiazide diuretics exacerbate fructose-induced metabolic syndrome. J Am Soc Nephrol (2007) 2.24
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol (2003) 2.24
Serum irisin levels in new-onset type 2 diabetes. Diabetes Res Clin Pract (2013) 2.03
Endothelial dysfunction: a link among preeclampsia, recurrent pregnancy loss, and future cardiovascular events? Hypertension (2006) 2.02
Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats. Kidney Int (2005) 2.02
Increased fructose associates with elevated blood pressure. J Am Soc Nephrol (2010) 2.01
TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int (2004) 1.95
Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats. Am J Physiol Renal Physiol (2006) 1.94
Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease. FASEB J (2003) 1.93
Reduction of renal immune cell infiltration results in blood pressure control in genetically hypertensive rats. Am J Physiol Renal Physiol (2002) 1.89
J-shaped mortality relationship for uric acid in CKD. Am J Kidney Dis (2006) 1.88
Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo. Circ Res (2002) 1.87
Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation. J Am Soc Nephrol (2002) 1.86
Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury. J Am Soc Nephrol (2003) 1.84
Human vascular smooth muscle cells express a urate transporter. J Am Soc Nephrol (2006) 1.83
CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance. Pediatr Nephrol (2013) 1.83
Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes (2011) 1.82
Role of uric acid in hypertension, renal disease, and metabolic syndrome. Cleve Clin J Med (2006) 1.81
Oxidative stress with an activation of the renin-angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction. J Hypertens (2010) 1.80
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH. Cell Metab (2010) 1.80
Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids (2008) 1.76
Serum uric acid as a predictor for development of diabetic nephropathy in type 1 diabetes: an inception cohort study. Diabetes (2009) 1.76
Oxidative stress, renal infiltration of immune cells, and salt-sensitive hypertension: all for one and one for all. Am J Physiol Renal Physiol (2004) 1.76
Activation of NAD(P)H:quinone oxidoreductase 1 prevents arterial restenosis by suppressing vascular smooth muscle cell proliferation. Circ Res (2009) 1.75
Renal angiotensin II concentration and interstitial infiltration of immune cells are correlated with blood pressure levels in salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol (2007) 1.74
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. Proc Natl Acad Sci U S A (2012) 1.72
Urinary CD80 excretion increases in idiopathic minimal-change disease. J Am Soc Nephrol (2008) 1.72
Pathophysiological mechanisms of salt-dependent hypertension. Am J Kidney Dis (2007) 1.71
Uric acid, endothelial dysfunction and pre-eclampsia: searching for a pathogenetic link. J Hypertens (2004) 1.71
Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells. Am J Physiol Cell Physiol (2008) 1.69
Molecular physiology of urate transport. Physiology (Bethesda) (2005) 1.69
Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice. Am J Physiol Renal Physiol (2009) 1.69
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. Am J Physiol Renal Physiol (2008) 1.68
Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules. J Am Soc Nephrol (2003) 1.68
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver. J Biol Chem (2012) 1.67
Microvascular disease and its role in the brain and cardiovascular system: a potential role for uric acid as a cardiorenal toxin. Nephrol Dial Transplant (2010) 1.65
The conundrum of hyperuricemia, metabolic syndrome, and renal disease. Intern Emerg Med (2008) 1.65
Fructose, but not dextrose, accelerates the progression of chronic kidney disease. Am J Physiol Renal Physiol (2007) 1.65
Mild hyperuricemia induces glomerular hypertension in normal rats. Am J Physiol Renal Physiol (2002) 1.64
Systemic inflammation, metabolic syndrome and progressive renal disease. Nephrol Dial Transplant (2009) 1.63
Inactivation of nitric oxide by uric acid. Nucleosides Nucleotides Nucleic Acids (2008) 1.59
The role of uric acid in the pathogenesis of human cardiovascular disease. Heart (2013) 1.59
Impaired renal function further increases odds of 6-year coronary artery calcification progression in adults with type 1 diabetes: the CACTI study. Diabetes Care (2013) 1.58
Glomerular hemodynamic changes associated with arteriolar lesions and tubulointerstitial inflammation. Kidney Int Suppl (2003) 1.57
Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes. Hepatology (2012) 1.57
Could uric acid have a role in acute renal failure? Clin J Am Soc Nephrol (2006) 1.56
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase. Hepatology (2013) 1.56
Relationship between serum adiponectin and leptin concentrations and body fat distribution. Diabetes Res Clin Pract (2004) 1.55
Prevalence and risk factors associated with chronic kidney disease in an adult population from southern China. Nephrol Dial Transplant (2008) 1.55
Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation. Kidney Int (2011) 1.55
Uric acid, the metabolic syndrome, and renal disease. J Am Soc Nephrol (2006) 1.54
Serum uric acid predicts vascular complications in adults with type 1 diabetes: the coronary artery calcification in type 1 diabetes study. Acta Diabetol (2014) 1.48
Association of urinary sodium/creatinine ratio with bone mineral density in postmenopausal women: KNHANES 2008-2011. Endocrine (2015) 1.48
Effects of cyclosporine in osteopontin null mice. Kidney Int (2002) 1.47
Fructose induces the inflammatory molecule ICAM-1 in endothelial cells. J Am Soc Nephrol (2008) 1.46
Serum uric acid levels predict the development of albuminuria over 6 years in patients with type 1 diabetes: findings from the Coronary Artery Calcification in Type 1 Diabetes study. Nephrol Dial Transplant (2010) 1.45
Endothelial dysfunction as a potential contributor in diabetic nephropathy. Nat Rev Nephrol (2010) 1.43
Hypothesis: Uric acid, nephron number, and the pathogenesis of essential hypertension. Kidney Int (2004) 1.42
IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease. J Am Soc Nephrol (2005) 1.41
Serum uric acid and hypertension in adults: a paradoxical relationship in type 1 diabetes. J Clin Hypertens (Greenwich) (2014) 1.41
A randomized study of allopurinol on endothelial function and estimated glomular filtration rate in asymptomatic hyperuricemic subjects with normal renal function. Clin J Am Soc Nephrol (2011) 1.40
Hyperuricemia causes glomerular hypertrophy in the rat. Am J Nephrol (2002) 1.39
Effects of febuxostat on metabolic and renal alterations in rats with fructose-induced metabolic syndrome. Am J Physiol Renal Physiol (2008) 1.38
Resurrection of uric acid as a causal risk factor in essential hypertension. Hypertension (2004) 1.38
Serum uric acid: a risk factor and a target for treatment? J Am Soc Nephrol (2006) 1.35
Dietary fructose causes tubulointerstitial injury in the normal rat kidney. Am J Physiol Renal Physiol (2010) 1.34
Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans. Environ Health Perspect (2009) 1.34
Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter. Am J Nephrol (2005) 1.33
Effects of acute and chronic L-arginine treatment in experimental hyperuricemia. Am J Physiol Renal Physiol (2006) 1.33
Orphan nuclear receptor small heterodimer partner represses hepatocyte nuclear factor 3/Foxa transactivation via inhibition of its DNA binding. Mol Endocrinol (2004) 1.30
Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse. Am J Physiol Renal Physiol (2008) 1.28
Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake. Metabolism (2011) 1.27
Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. Hepatology (2008) 1.27