Published in Stem Cells on October 27, 2005
Human embryonic stem cells have a unique epigenetic signature. Genome Res (2006) 2.89
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A (2007) 2.60
Quality of Cell Products: Authenticity, Identity, Genomic Stability and Status of Differentiation. Transfus Med Hemother (2010) 1.00
Threshold in stage-specific embryonic glycotypes uncovered by a full portrait of dynamic N-glycan expression during cell differentiation. Mol Cell Proteomics (2009) 0.96
Recurrent genomic instability of chromosome 1q in neural derivatives of human embryonic stem cells. J Clin Invest (2012) 0.95
Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V. BMC Cell Biol (2009) 0.91
Genetic stability of bone marrow-derived human mesenchymal stromal cells in the Quantum System. Cytotherapy (2013) 0.90
Proteomic analysis of stem cell differentiation and early development. Cold Spring Harb Perspect Biol (2012) 0.86
Enabling consistency in pluripotent stem cell-derived products for research and development and clinical applications through material standards. Stem Cells Transl Med (2015) 0.82
Immunocytochemical analysis of human pluripotent stem cells. Methods Mol Biol (2011) 0.78
Human embryonic and induced pluripotent stem cell research trends: complementation and diversification of the field. Stem Cell Reports (2015) 0.77
Determine the quality of human embryonic stem colonies with laser light scattering patterns. Biol Proced Online (2013) 0.75
Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications. Stem Cell Rev (2016) 0.75
Regulatory networks define phenotypic classes of human stem cell lines. Nature (2008) 4.98
Gene expression in human embryonic stem cell lines: unique molecular signature. Blood (2003) 3.73
Differences between human and mouse embryonic stem cells. Dev Biol (2004) 3.30
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood (2007) 3.05
Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease. Stem Cells (2005) 2.74
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat Neurosci (2008) 2.67
Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol (2004) 2.60
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation. Nat Med (2005) 2.46
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem (2002) 2.45
Dopaminergic differentiation of human embryonic stem cells. Stem Cells (2004) 2.30
Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation. Stem Cells Dev (2014) 2.27
Long-term culture of human embryonic stem cells in feeder-free conditions. Dev Dyn (2004) 2.01
Properties of a fetal multipotent neural stem cell (NEP cell). Dev Biol (2002) 1.75
Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001. Stem Cells Dev (2004) 1.75
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (2010) 1.74
Membrane properties of rat embryonic multipotent neural stem cells. J Neurochem (2004) 1.73
CD44 expression identifies astrocyte-restricted precursor cells. Dev Biol (2004) 1.66
Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research. Stem Cells (2007) 1.62
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies. BMC Dev Biol (2005) 1.61
Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev Dyn (2004) 1.60
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. Stem Cells (2009) 1.59
Assessing self-renewal and differentiation in human embryonic stem cell lines. Stem Cells (2005) 1.58
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines. BMC Dev Biol (2006) 1.58
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. PLoS Biol (2009) 1.57
Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain. Dev Biol (2003) 1.53
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS. J Comp Neurol (2007) 1.51
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells. BMC Dev Biol (2008) 1.49
Developing safe therapies from human pluripotent stem cells. Nat Biotechnol (2009) 1.48
Toward cell replacement therapy: promises and caveats. Exp Neurol (2003) 1.47
Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain. Aging Cell (2005) 1.42
Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol (2005) 1.41
Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them. PLoS One (2009) 1.38
Brg1 is required for murine neural stem cell maintenance and gliogenesis. Dev Biol (2005) 1.38
Properties of pluripotent human embryonic stem cells BG01 and BG02. Stem Cells (2004) 1.36
Creation of engineered human embryonic stem cell lines using phiC31 integrase. Stem Cells (2007) 1.35
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes. J Neurosci Res (2007) 1.31
Oligodendrocyte and astrocyte development in rodents: an in situ and immunohistological analysis during embryonic development. Glia (2002) 1.31
Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells. Glia (2006) 1.28
Adult glial precursor proliferation in mutant SOD1G93A mice. Glia (2008) 1.27
A novel serum-free medium for the expansion of human mesenchymal stem cells. Stem Cell Res Ther (2010) 1.26
Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation. PLoS One (2008) 1.24
Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Exp Neurol (2002) 1.23
Immortalized neural stem cells differ from nonimmortalized cortical neurospheres and cerebellar granule cell progenitors. Exp Neurol (2004) 1.23
BG01V: a variant human embryonic stem cell line which exhibits rapid growth after passaging and reliable dopaminergic differentiation. Restor Neurol Neurosci (2004) 1.22
A review of the methods for human iPSC derivation. Methods Mol Biol (2013) 1.22
In search of "stemness". Exp Hematol (2004) 1.21
The stem-cell menagerie. Trends Neurosci (2003) 1.20
An efficient method for the derivation of mouse embryonic stem cells. Stem Cells (2005) 1.20
Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan. Stem Cells Dev (2004) 1.15
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS. PLoS One (2011) 1.14
The microenvironment of the embryonic neural stem cell: lessons from adult niches? Dev Dyn (2007) 1.14
Monitoring differentiation of human embryonic stem cells using real-time PCR. Stem Cells (2005) 1.11
SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors. Neurosci Lett (2006) 1.09
NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells. Stem Cells Dev (2005) 1.08
Hes1 but not Hes5 regulates an astrocyte versus oligodendrocyte fate choice in glial restricted precursors. Dev Dyn (2003) 1.07
Global Characterization and Genomic Stability of Human MultiStem, A Multipotent Adult Progenitor Cell. J Stem Cells (2009) 1.06
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. ALTEX (2010) 1.06
Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Res (2005) 1.06
Embryonic stem cell research and U.S. policy. Stem Cells (2006) 1.06
Glial progenitors in the CNS and possible lineage relationships among them. Biol Cell (2004) 1.05
Efficient generation of astrocytes from human pluripotent stem cells in defined conditions. Stem Cells (2013) 1.05
Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue. Stem Cells (2007) 1.05
Human neural crest stem cells derived from human ESCs and induced pluripotent stem cells: induction, maintenance, and differentiation into functional schwann cells. Stem Cells Transl Med (2012) 1.05
Cellular lifespan and senescence signaling in embryonic stem cells. Aging Cell (2004) 1.04
Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation. Exp Neurol (2006) 1.04
Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus. Stem Cells (2007) 1.03
Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron Glia Biol (2004) 1.02
Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research. Stem Cells (2005) 1.01
Neurogenesis in Talpha-1 tubulin transgenic mice during development and after injury. Exp Neurol (2005) 1.01
Transcriptome coexpression map of human embryonic stem cells. BMC Genomics (2006) 1.01
Stage-specific role for shh in dopaminergic differentiation of human embryonic stem cells induced by stromal cells. Stem Cells Dev (2010) 1.00
Mechanisms controlling embryonic stem cell self-renewal and differentiation. Crit Rev Eukaryot Gene Expr (2006) 1.00
Olig genes are expressed in a heterogeneous population of precursor cells in the developing spinal cord. Glia (2004) 1.00
CD44 overexpression by oligodendrocytes: a novel mouse model of inflammation-independent demyelination and dysmyelination. Glia (2004) 0.98
Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells. Genomics (2006) 0.98
Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent. Glia (2006) 0.98
Gene expression profile of neuronal progenitor cells derived from hESCs: activation of chromosome 11p15.5 and comparison to human dopaminergic neurons. PLoS One (2008) 0.97
hESC-derived Olig2+ progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. Nat Commun (2013) 0.97
Glutamate transporter expression and function in human glial progenitors. Glia (2004) 0.97
Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism. J Neurochem (2006) 0.97
An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP+ toxicity and GDNF neuroprotection. Neuropsychopharmacology (2006) 0.97
Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Exp Neurol (2002) 0.96
Stage-dependent Olig2 expression in motor neurons and oligodendrocytes differentiated from embryonic stem cells. Stem Cells Dev (2007) 0.96
Evaluation of cholesterol reduction activity of methyl-β-cyclodextrin using differentiated human neurons and astrocytes. J Biomol Screen (2012) 0.95
Estimating human embryonic stem-cell numbers. Lancet (2006) 0.95
Glial restricted precursors protect against chronic glutamate neurotoxicity of motor neurons in vitro. Glia (2005) 0.95
A large-scale proteomic analysis of human embryonic stem cells. BMC Genomics (2007) 0.95
Expression profiling of human glial precursors. BMC Dev Biol (2008) 0.94
Transdifferentiation--fact or artifact. J Cell Biochem (2003) 0.94
Functional screening assays with neurons generated from pluripotent stem cell-derived neural stem cells. J Biomol Screen (2013) 0.93
Using human pluripotent stem cell-derived dopaminergic neurons to evaluate candidate Parkinson's disease therapeutic agents in MPP+ and rotenone models. J Biomol Screen (2013) 0.93
Chromatin insulator elements block transgene silencing in engineered human embryonic stem cell lines at a defined chromosome 13 locus. Stem Cells Dev (2011) 0.92
Functional SDF1 alpha/CXCR4 signaling in the developing spinal cord. J Neurochem (2005) 0.92
Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology? Stem Cell Rev (2011) 0.92
Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V. BMC Cell Biol (2009) 0.91
A focused microarray to assess dopaminergic and glial cell differentiation from fetal tissue or embryonic stem cells. Stem Cells (2005) 0.91
Novel live alkaline phosphatase substrate for identification of pluripotent stem cells. Stem Cell Rev (2012) 0.91
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. Stem Cells Dev (2013) 0.91