PubRank

Jürgen Harder

Author PubWeight™ 52.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection. Nat Immunol 2004 3.19
2 NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium. Infect Immun 2004 2.47
3 Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cells. J Immunol 2008 2.13
4 NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2. J Biol Chem 2005 2.06
5 Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med 2011 1.74
6 Degradation by stratum corneum proteases prevents endogenous RNase inhibitor from blocking antimicrobial activities of RNase 5 and RNase 7. J Invest Dermatol 2009 1.70
7 RNase 7 protects healthy skin from Staphylococcus aureus colonization. J Invest Dermatol 2010 1.69
8 Epidermal EGFR controls cutaneous host defense and prevents inflammation. Sci Transl Med 2013 1.69
9 Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence. Dev Comp Immunol 2008 1.55
10 Production of endogenous antibiotics in articular cartilage. Arthritis Rheum 2004 1.55
11 UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol 2009 1.31
12 Burkholderia is highly resistant to human Beta-defensin 3. Antimicrob Agents Chemother 2003 1.29
13 Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract. Kidney Int 2011 1.25
14 Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection. BMC Infect Dis 2002 1.20
15 The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption. J Invest Dermatol 2008 1.18
16 Psoriasin (S100A7) is significantly up-regulated in human epithelial skin tumours. J Cancer Res Clin Oncol 2006 1.15
17 Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines. Eur Urol 2006 1.12
18 Mouse beta-defensin-14, an antimicrobial ortholog of human beta-defensin-3. Antimicrob Agents Chemother 2008 1.07
19 RNase 7 contributes to the cutaneous defense against Enterococcus faecium. PLoS One 2009 1.06
20 Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1. J Invest Dermatol 2006 1.03
21 Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14. J Invest Dermatol 2010 0.99
22 Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells. BMC Urol 2008 0.98
23 Highly complex peptide aggregates of the S100 fused-type protein hornerin are present in human skin. J Invest Dermatol 2008 0.95
24 Antimicrobial RNases in cutaneous defense. J Innate Immun 2012 0.93
25 Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors. Arthritis Rheum 2005 0.92
26 Identification of RNase 8 as a novel human antimicrobial protein. Antimicrob Agents Chemother 2006 0.91
27 Differential expression pattern of antimicrobial peptides in nasal mucosa and secretion. Rhinology 2011 0.88
28 Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus. Invest Ophthalmol Vis Sci 2011 0.87
29 IL-17A and IFN-γ synergistically induce RNase 7 expression via STAT3 in primary keratinocytes. PLoS One 2013 0.87
30 Activity of human beta-defensins 2 and 3 against ESBL-producing Klebsiella strains. J Antimicrob Chemother 2006 0.86
31 Lipid-specific membrane activity of human beta-defensin-3. Biochemistry 2006 0.86
32 Paraoxonase 2 acts as a quorum sensing-quenching factor in human keratinocytes. J Invest Dermatol 2012 0.86
33 Differential expression and in vivo secretion of the antimicrobial peptides psoriasin (S100A7), RNase 7, human beta-defensin-2 and -3 in healthy human skin. Exp Dermatol 2013 0.86
34 Differential expression of antimicrobial peptides in margins of chronic wounds. Exp Dermatol 2010 0.85
35 Differential suppression of epidermal antimicrobial protein expression in atopic dermatitis and in EFAD mice by pimecrolimus compared to corticosteroids. Exp Dermatol 2011 0.85
36 Antimicrobial peptides in oral cancer. Curr Pharm Des 2007 0.84
37 Functional expression of the intracellular pattern recognition receptor NOD1 in human keratinocytes. J Invest Dermatol 2009 0.83
38 Human beta-defensin-2 in oral cancer with opportunistic Candida infection. Anticancer Res 2004 0.83
39 Psoriasin: key molecule of the cutaneous barrier? J Dtsch Dermatol Ges 2011 0.81
40 Oesophageal defensin expression during Candida infection and reflux disease. Scand J Gastroenterol 2005 0.81
41 Prenatal human skin expresses the antimicrobial peptide RNase 7. Arch Dermatol Res 2013 0.78
42 Staphylococcus aureus subverts cutaneous defense by D-alanylation of teichoic acids. Exp Dermatol 2013 0.78
43 Expression of antimicrobial peptides in atopic dermatitis and possible immunoregulatory functions. Curr Opin Allergy Clin Immunol 2013 0.77
44 Human skin engages different epidermal layers to provide distinct innate defense mechanisms. Exp Dermatol 2014 0.76
45 Bacterial soft tissue infection in psoriasis despite induction of epidermal antimicrobial peptides. Exp Dermatol 2014 0.75
46 Human beta-defensin-2 increases cholinergic response in colon epithelium. Pflugers Arch 2010 0.75
47 [Innate antimicrobial peptides in the skin]. Med Sci (Paris) 2006 0.75
48 Susceptibility of Staphylococcus aureus bacteremia strains to different skin-derived antimicrobial proteins. Arch Dermatol Res 2012 0.75