Published in J Virol on March 01, 1975
Regulation of tumor antigen synthesis by simain virus 40 gene A. J Virol (1975) 9.93
Ubiquitous, interspersed repeated sequences in mammalian genomes. Proc Natl Acad Sci U S A (1980) 9.48
Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens. J Virol (1980) 7.51
Simian virus 40 functions required for the establishment and maintenance of malignant transformation. J Virol (1975) 6.79
Role of simian virus 40 gene A function in maintenance of transformation. J Virol (1975) 6.63
Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen. Proc Natl Acad Sci U S A (1977) 6.57
Simian virus 40 gene A function and maintenance of transformation. J Virol (1975) 6.40
Simian virus 40 early mRNA's. I. Genomic localization of 3' and 5' termini and two major splices in mRNA from transformed and lytically infected cells. J Virol (1979) 5.93
Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse. Proc Natl Acad Sci U S A (1991) 5.52
Integrated simian virus 40 sequences in transformed cell DNA: analysis using restriction endonucleases. Proc Natl Acad Sci U S A (1976) 4.92
Patterns of organization of actin and myosin in normal and transformed cultured cells. Proc Natl Acad Sci U S A (1975) 4.86
UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol Cell Biol (1984) 4.83
Production of infectious poliovirus from cloned cDNA is dramatically increased by SV40 transcription and replication signals. Nucleic Acids Res (1984) 4.19
Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus. J Virol (1977) 4.07
Enzymatic activities associated with a purified simian virus 40 T antigen-related protein. Proc Natl Acad Sci U S A (1979) 3.82
Modification of simian virus 40 protein A. J Virol (1977) 3.79
Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell (1984) 3.56
Characterization of the autoregulation of simian virus 40 gene A. J Virol (1977) 3.45
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants. Mol Cell Biol (1983) 3.06
Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex. J Virol (1986) 3.04
Identification and partial characterization of new antigens from simian virus 40-transformed mouse cells. J Virol (1979) 3.04
Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Mol Cell Biol (1986) 2.81
Differential affinities of simian virus 40 large tumor antigen for DNA. Proc Natl Acad Sci U S A (1980) 2.75
Monomer molecular weight of T antigen from simian virus 40-infected and transformed cells. Proc Natl Acad Sci U S A (1976) 2.64
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci U S A (1993) 2.58
Biological activity of purified simian virus 40 T antigen proteins. Proc Natl Acad Sci U S A (1978) 2.54
Extraction and fingerprint analysis of simian virus 40 large and small T-antigens. J Virol (1978) 2.50
State and organization of polyoma virus DNA sequences in transformed rat cell lines. J Virol (1979) 2.47
Cellular proteins associated with simian virus 40 early gene products in newly infected cells. J Virol (1979) 2.44
Transformation of BALB/c-3T3 cells by tsA mutants of simian virus 40: temperature sensitivity of the transformed phenotype and retransofrmation by wild-type virus. J Virol (1978) 2.42
Cell-free synthesis of simian virus 40 T-antigens. J Virol (1978) 2.32
Thermolabile T (tumor) antigen from cells transformed by a temperature-sensitive mutant of simian virus 40. Proc Natl Acad Sci U S A (1975) 2.32
Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells. Proc Natl Acad Sci U S A (1982) 2.29
Properties of simian virus 40 small t antigen overproduced in bacteria. J Virol (1981) 2.08
Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature. Mol Cell Biol (1989) 2.04
Properties of permissive monkey cells transformed by UV-irradiated simian virus 40. J Virol (1977) 2.03
The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions. J Virol (1989) 2.00
Evidence for simian virus 40 (SV40) coding of SV40 T-antigen and the SV40-specific proteins in HeLa cells infected with nondefective adenovirus type 2-SV40 hybrid viruses. J Virol (1977) 1.94
Properties of the simian virus 40 (SV40) large T antigens encoded by SV40 mutants with deletions in gene A. J Virol (1986) 1.86
Growth control in simian virus 40-transformed rat cells: temperature-independent expression of the transformed phenotype in tsA transformants derived by agar selection. J Virol (1978) 1.81
Mutational analysis of simian virus 40 T antigen: stimulation of cellular DNA synthesis and activation of rRNA genes by mutants with deletions in the T-antigen gene. Mol Cell Biol (1983) 1.81
Effect of alkylation on the physical properties of simian virus 40 T-antigen species. J Virol (1979) 1.77
Solubilization of the Epstein-Barr virus-determined nuclear antigen and its characterization as a DNA-binding protein. J Virol (1977) 1.75
Protein kinase activity associated with simian virus 40 T antigen. Proc Natl Acad Sci U S A (1979) 1.72
Different forms of simian virus 40 large tumor antigen varying in their affinities for DNA. J Virol (1982) 1.72
Synthesis of simian virus 40 t antigen in Escherichia coli. Proc Natl Acad Sci U S A (1979) 1.70
Measurements of the molecular size of the simian virus 40 large T antigen. J Virol (1978) 1.70
Cellular and cell-free synthesis of simian virus 40 T-antigens in permissive and transformed cells. J Virol (1978) 1.66
Biological and biochemical studies of cells transformed by simian virus 40 temperature-sensitive gene A mutants and A mutant revertants. J Virol (1977) 1.64
Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proc Natl Acad Sci U S A (1988) 1.62
Purification of biologically active simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1983) 1.61
Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution. Proc Natl Acad Sci U S A (1985) 1.59
Growth state of the cell early after infection with simian virus 40 determines whether the maintenance of transformation will be A-gene dependent or independent. J Virol (1979) 1.51
Simian virus 40 large T-antigen point mutants that are defective in viral DNA replication but competent in oncogenic transformation. Mol Cell Biol (1984) 1.51
Critical spatial requirement within the origin of simian virus 40 DNA replication. J Virol (1984) 1.49
Simian virus to (SV40) tumor-specific proteins in nucleus and plasma membrane of HeLa cells infected by adenovirus 2-SV40 hybrid virus Ad2+ND2. Proc Natl Acad Sci U S A (1976) 1.49
Mutants deleted in the agnogene of simian virus 40 define a new complementation group. J Virol (1983) 1.48
Conditions leading to the establishment of the N (a gene dependent) and A (a gene independent) transformed states after polyoma virus infection of rat fibroblasts. J Virol (1978) 1.43
Resting state in normal and simian virus 40 transformed Chinese hamster lung cells. Proc Natl Acad Sci U S A (1976) 1.33
Mutational analysis of simian virus 40 large T antigen DNA binding sites. EMBO J (1984) 1.31
Two separable functional domains of simian virus 40 large T antigen: carboxyl-terminal region of simian virus 40 large T antigen is required for efficient capsid protein synthesis. J Virol (1985) 1.31
Differential ability of a T-antigen transport-defective mutant of simian virus 40 to transform primary and established rodent cells. Mol Cell Biol (1985) 1.30
Nonviable mutants of simian virus 40 with deletions near the 3' end of gene A define a function for large T antigen required after onset of viral DNA replication. J Virol (1983) 1.30
Phosphorylation of threonine in the proline-rich carboxy-terminal region of simian virus 40 large T antigen. J Virol (1981) 1.29
Intracistronic complementation in the simian virus 40 A gene. Proc Natl Acad Sci U S A (1983) 1.28
Relationship between T-antigen and tumor-specific transplantation antigen in simian virus 40-transformed cells. J Virol (1979) 1.27
Evidence for two classes of chromatin-associated Epstein-Barr virus-determined nuclear antigen. J Virol (1982) 1.25
DNA binding properties of simian virus 40 T-antigens synthesized in vivo and in vitro. J Virol (1980) 1.24
Protein kinase activity associated with the D2 hybrid protein related to simian virus 40 T antigen: some characteristics of the reaction products. Proc Natl Acad Sci U S A (1979) 1.24
Construction and characterization of viable deletion mutants of simian virus 40 lacking sequences near the 3' end of the early region. J Virol (1982) 1.23
Persistence of type 5 adenovirus DNA in cells transformed by temperature-sensitive mutant, H5ts125. Proc Natl Acad Sci U S A (1977) 1.23
Nonlytic simian virus 40-specific 100K phosphoprotein is associated with anchorage-independent growth in simian virus 40-transformed and revertant mouse cell lines. Mol Cell Biol (1981) 1.22
Transformation of primary rat kidney cells by fragments of simian virus 40 DNA. J Virol (1975) 1.22
Two classes of transformation-deficient, immortalization-positive simian virus 40 mutants constructed by making three-base insertions in the T antigen gene. J Virol (1984) 1.21
Simian virus 40 gene A regulation of cellular DNA synthesis. I. In permissive cells. J Virol (1979) 1.21
Metabolic turnover of phosphorylation sites in simian virus 40 large T antigen. J Virol (1983) 1.19
Identification of simian virus 40 tumor and U antigens. Proc Natl Acad Sci U S A (1977) 1.17
Regulation of viral transciption and tumor antigen expression in cells transformed by simian virus 40. Proc Natl Acad Sci U S A (1976) 1.17
Simian virus 40 gene A regulates the association between a highly phosphorylated protein and chromatin and ribosomes in simian virus 40-transformed cells. J Virol (1977) 1.15
Expression and thermal stability of simian virus 40 tumor-specific transplantation antigen and tumor antigen in wild type- and tsA mutant-transformed cells. J Virol (1977) 1.15
Purification of simian virus 40 tumor antigen from a line of simian virus 40-transformed human cells. Proc Natl Acad Sci U S A (1977) 1.14
trans-dominant defective mutants of simian virus 40 T antigen. J Virol (1987) 1.14
The history of tumor virology. Cancer Res (2008) 1.14
Identification and initial characterization of a new low-molecular-weight virus-encoded T antigen in a line of simian virus 40-transformed cells. J Virol (1980) 1.11
A functional simian virus 40 origin of replication is required for the generation of a super T antigen with a molecular weight of 100,000 in transformed mouse cells. J Virol (1983) 1.10
Integration of the simian virus 40 genome into cellular DNA in temperature-sensitive (N) and temperature-insensitive (A) transformants of 3T3 rat and Chinese hamster lung cells. J Virol (1980) 1.09
Human placental cells transformed by tsA mutants of simian virus 40: a model system for the study of placental functions. Proc Natl Acad Sci U S A (1978) 1.08
Replication and transformation functions of in vitro-generated simian virus 40 large T antigen mutants. J Virol (1986) 1.08
Analysis of a transgenic mouse containing simian virus 40 and v-myc sequences. Mol Cell Biol (1985) 1.07
Isolation of cellular genes differentially expressed in mouse NIH 3T3 cells and a simian virus 40-transformed derivative: growth-specific expression of VL30 genes. Mol Cell Biol (1985) 1.06
Polyoma genome in hamster BHK-21-C13 cells: integration into cellular DNA and induction of the viral replication. J Virol (1976) 1.06
Transformation of human skeletal muscle cells by simian virus 40. Proc Natl Acad Sci U S A (1983) 1.05
Characterization of flat revertant cells isolated from simian virus 40-transformed mouse and rat cells which contain multiple copies of viral genomes. J Virol (1981) 1.05
A simian virus 40 dl884/tsA58 double mutant is temperature sensitive for abortive transformation. J Virol (1983) 1.04
Presence of allograft-rejection resistance in simian virus 40-transformed hamster cells and its possible role in tumor development. Proc Natl Acad Sci U S A (1980) 1.04
Transformation of BALB/c-3T3 cells by tsA mutants of simian virus 40: effect of transformation technique on the transformed phenotype. J Virol (1980) 1.04
Antigenic structure of simian virus 40 large tumor antigen and association with cellular protein p53 on the surfaces of simian virus 40-infected and -transformed cells. J Virol (1984) 1.04
Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon. J Virol (1972) 16.59
DETECTION OF SPECIFIC ANTIGEN IN SV40-TRANSFORMED CELLS BY IMMUNOFLUORESCENCE. J Exp Med (1964) 11.41
Temperature-sensitive mutants of simian virus 40: infection of permissive cells. J Virol (1971) 7.95
Simian virus 40 functions required for the establishment and maintenance of malignant transformation. J Virol (1975) 6.79
Role of simian virus 40 gene A function in maintenance of transformation. J Virol (1975) 6.63
Simian virus 40 gene A function and maintenance of transformation. J Virol (1975) 6.40
Complementation and transformation by temperature-sensitive mutants of polyoma virus. Virology (1969) 6.04
Inactivating and mutagenic effects of nitrosoguanidine on simian virus 40. Proc Natl Acad Sci U S A (1970) 5.46
Viral DNA synthesis in cells infected by temperature-sensitive mutants of simian virus 40. J Virol (1974) 5.44
CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS. Proc Natl Acad Sci U S A (1965) 4.73
Temperature-sensitive mutants of polyoma virus. Virology (1969) 4.45
Polyoma gene function required for viral DNA synthesis. Virology (1973) 4.37
Relationship of replication and transcription of Simian Virus 40 DNA. Proc Natl Acad Sci U S A (1973) 4.35
A temperature-sensitive mutant of simian virus 40 affecting transforming ability. Virology (1973) 4.11
Effect of cell chromosome number on simian virus 40 replication. Exp Cell Res (1973) 3.20
High frequency of SV40 transformation of mouse cell line 3T3. Virology (1966) 3.04
Transformation of mouse cell line 3T3 by SV40: dose response relationship and correlation with SV40 tumor antigen production. Virology (1966) 2.34
Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon. J Virol (1972) 16.59
Regulation of tumor antigen synthesis by simain virus 40 gene A. J Virol (1975) 9.93
Temperature-sensitive mutants of simian virus 40: infection of permissive cells. J Virol (1971) 7.95
Organization and expression of early genes of simian virus 40. Proc Natl Acad Sci U S A (1978) 7.10
Inactivating and mutagenic effects of nitrosoguanidine on simian virus 40. Proc Natl Acad Sci U S A (1970) 5.46
Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication. J Virol (1983) 5.00
Identification of simian virus 40 protein A. J Virol (1977) 4.93
Relationship of replication and transcription of Simian Virus 40 DNA. Proc Natl Acad Sci U S A (1973) 4.35
Altered patterns of protein synthesis in infection by SV40 mutants. Cold Spring Harb Symp Quant Biol (1975) 4.30
Modification of simian virus 40 protein A. J Virol (1977) 3.79
Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J Virol (1986) 3.15
An altered DNA conformation in origin region I is a determinant for the binding of SV40 large T antigen. Cell (1986) 2.88
Topography of simian virus 40 A protein-DNA complexes: arrangement of protein bound to the origin of replication. J Virol (1983) 2.79
p53 domains: identification and characterization of two autonomous DNA-binding regions. Genes Dev (1993) 2.74
Domain structure of the simian virus 40 core origin of replication. Mol Cell Biol (1986) 2.72
Proposal for a uniform nomenclature for simian virus 40 mutants. J Virol (1972) 2.55
ATP enhances the binding of simian virus 40 large T antigen to the origin of replication. J Virol (1987) 2.43
The adenine-thymine domain of the simian virus 40 core origin directs DNA bending and coordinately regulates DNA replication. Mol Cell Biol (1986) 2.31
Simian virus 40 deoxyribonucleic acid synthesis: analysis by gel electrophoresis. J Virol (1972) 2.31
DNA binding properties of simian virus 40 temperature-sensitive A proteins. J Virol (1982) 2.31
Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen. J Virol (1990) 2.24
Alternative interactions of the SV40 A protein with DNA. Virology (1981) 2.09
The T-antigen-binding domain of the simian virus 40 core origin of replication. J Virol (1987) 2.08
Synthesis and assembly of simian virus 40. II. Synthesis of the major capsid protein and its incorporation into viral particles. J Virol (1972) 2.01
Altered protein metabolism in infection by the late tsB11 mutant of simian virus 40. J Virol (1974) 1.94
Role of cysteine residues in regulation of p53 function. Mol Cell Biol (1995) 1.91
Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitro. Proc Natl Acad Sci U S A (1987) 1.89
Cooperative assembly of simian virus 40 T-antigen hexamers on functional halves of the replication origin. J Virol (1991) 1.78
Sequence-specific binding of simian virus 40 A protein to nonorigin and cellular DNA. Mol Cell Biol (1984) 1.68
p53 domains: structure, oligomerization, and transformation. Mol Cell Biol (1994) 1.68
Formation of stable p53 homotetramers and multiples of tetramers. Mol Carcinog (1992) 1.68
Seventeen base pairs of region I encode a novel tripartite binding signal for SV40 T antigen. Cell (1985) 1.64
Herpes simplex virus origin-binding protein (UL9) loops and distorts the viral replication origin. J Virol (1991) 1.62
Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution. Proc Natl Acad Sci U S A (1985) 1.59
p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J (1994) 1.57
Feline herpesvirus infection in fused cultures of naturally resistant human cells. J Virol (1969) 1.52
The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation. Proc Natl Acad Sci U S A (1995) 1.52
Partial purification of SV40 A protein and a related cellular protein from permissive cells. Virology (1981) 1.51
Critical spatial requirement within the origin of simian virus 40 DNA replication. J Virol (1984) 1.49
Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding. J Virol (1990) 1.48
The zinc finger region of simian virus 40 large T antigen. J Virol (1989) 1.47
Replication but not transcription of simian virus 40 DNA is dependent on nuclear domain 10. J Virol (2000) 1.46
Interaction of p53 with its consensus DNA-binding site. Mol Cell Biol (1995) 1.40
Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein. J Virol (1988) 1.39
Binding of dephosphorylated A protein to SV40 DNA. Virology (1981) 1.30
Binding of simian virus 40 a protein to DNA with deletions at the origin of replication. J Virol (1984) 1.26
p53 domains: suppression, transformation, and transactivation. Gene Expr (1993) 1.24
Antigenic phenotypes and complementation groups of temperature-sensitive mutants of simian virus 40. J Virol (1974) 1.24
Serine phosphorylation in the NH2 terminus of p53 facilitates transactivation. Cancer Res (1995) 1.24
Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation. Mol Cell Biol (1997) 1.23
The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting. J Virol (1991) 1.16
cdc2 phosphorylation of threonine 124 activates the origin-unwinding functions of simian virus 40 T antigen. J Virol (1993) 1.15
Binding of SV40 a protein to the BK virus origin of DNA replication. Virology (1983) 1.14
Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen. J Virol (1989) 1.09
Mechanisms of simian virus 40 T-antigen activation by phosphorylation of threonine 124. J Virol (1996) 1.08
Morphological changes in productive and abortive infection by feline herpesvirus. J Virol (1970) 1.05
The human DNA-activated protein kinase phosphorylates simian virus 40 T antigen at amino- and carboxy-terminal sites. J Virol (1991) 1.02
Purification and characterization of the SV40 F-gene protein. Cold Spring Harb Symp Quant Biol (1980) 1.00
The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigen. J Virol (1989) 0.99
Spacing is crucial for coordination of domain functions within the simian virus 40 core origin of replication. J Virol (1992) 0.99
Synergistic transcriptional activation of the MCK promoter by p53: tetramers link separated DNA response elements by DNA looping. Oncogene (1998) 0.94
Identification of the human papovavirus T antigen and comparison with the simian virus 40 protein a. Virology (1977) 0.93
Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigen. J Virol (1992) 0.90
Isolation of AGMK cells partially resistant to SV40: identification of the resistant step. Proc Soc Exp Biol Med (1972) 0.89
Differential interaction of temperature-sensitive simian virus 40 T antigens with tumor suppressors pRb and p53. J Virol (1996) 0.82
Topoisomerase I sites cluster asymmetrically at the ends of the simian virus 40 core origin of replication. J Virol (1989) 0.81
The role of operator position in SV40 T-antigen-mediated repression. Virology (1988) 0.81
Giant leap for p53, small step for drug design. Bioessays (1995) 0.78
A genetic analysis of the zinc finger of SV40 large T antigen. Curr Top Microbiol Immunol (1989) 0.77
The quaternary structures of SV40 large T antigen and tumor suppressor p53: analysis by gel electrophoresis. Genet Eng (N Y) (1992) 0.75
[Recommendations for the husbandry and welfare of sheep and goats by the German Small Ruminant Veterinary Association. Part 2]. Tierarztl Prax Ausg G Grosstiere Nutztiere (2012) 0.75
[Recommendations for the husbandry and welfare of sheep and goats by the German Small Ruminant Veterinary Association. Part 1]. Tierarztl Prax Ausg G Grosstiere Nutztiere (2012) 0.75