Published in J Virol on June 01, 1980
Monoclonal antibodies specific for simian virus 40 tumor antigens. J Virol (1981) 15.59
Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol Cell Biol (1981) 6.02
Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Am J Pathol (1989) 5.41
UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells. Mol Cell Biol (1984) 4.83
Detection of a common feature in several human tumor cell lines--a 53,000-dalton protein. Proc Natl Acad Sci U S A (1981) 3.99
p53 transformation-related protein: detection by monoclonal antibody in mouse and human cells. Proc Natl Acad Sci U S A (1981) 3.72
Monoclonal antibody analysis of p53 expression in normal and transformed cells. J Virol (1986) 3.72
Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells. Proc Natl Acad Sci U S A (1982) 3.58
Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53. Mol Cell Biol (1983) 3.39
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. Proc Natl Acad Sci U S A (1990) 3.20
Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells. EMBO J (1985) 3.18
Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc Natl Acad Sci U S A (1985) 3.15
Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53. Mol Cell Biol (1985) 3.09
Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex. J Virol (1986) 3.04
Precise epitope mapping of the murine transformation-associated protein, p53. EMBO J (1985) 2.98
Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication. J Virol (1992) 2.96
Role of the p53 protein in cell proliferation as studied by microinjection of monoclonal antibodies. Mol Cell Biol (1984) 2.88
SV40 T antigen binds directly to the large subunit of purified DNA polymerase alpha. EMBO J (1990) 2.65
Complex of simian virus 40 large-T antigen and host 53,000-molecular-weight protein in monkey cells. J Virol (1981) 2.60
Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 2.59
Increased concentration of an apparently identical cellular protein in cells transformed by either Abelson murine leukemia virus or other transforming agents. J Virol (1981) 2.56
Detection and characterization of multiple forms of simian virus 40 large T antigen. J Virol (1981) 2.54
Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription. EMBO J (1992) 2.45
Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen. J Virol (1984) 2.41
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II. EMBO J (1990) 2.38
Radioimmunoassay of the cellular protein p53 in mouse and human cell lines. EMBO J (1982) 2.29
Cloning and expression analysis of full length mouse cDNA sequences encoding the transformation associated protein p53. Nucleic Acids Res (1984) 2.28
p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction. EMBO J (1996) 2.25
p53-catalyzed annealing of complementary single-stranded nucleic acids. EMBO J (1993) 2.16
Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens. Proc Natl Acad Sci U S A (1987) 2.15
Molecular basis for heterogeneity of the human p53 protein. Mol Cell Biol (1986) 2.14
Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining. EMBO J (1984) 2.08
p53, a transformation-related cellular-encoded protein, can be used as a biochemical marker for the detection of primary mouse tumor cells. Proc Natl Acad Sci U S A (1983) 2.03
Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences. Mol Cell Biol (1984) 2.00
Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression. Proc Natl Acad Sci U S A (1991) 1.99
Nuclear protein p68 is an RNA-dependent ATPase. EMBO J (1989) 1.98
Oligomerization of oncoprotein p53. J Virol (1988) 1.98
Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells. Mol Cell Biol (1985) 1.91
Cellular proteins reactive with monoclonal antibodies directed against simian virus 40 T-antigen. J Virol (1982) 1.90
An amber suppressor tRNA gene derived by site-specific mutagenesis: cloning and function in mammalian cells. Proc Natl Acad Sci U S A (1982) 1.86
A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system. J Virol (1985) 1.85
DNA-binding properties of simian virus 40 T-antigen mutants defective in viral DNA replication. Mol Cell Biol (1983) 1.76
Energy requirement for degradation of tumor-associated protein p53. Mol Cell Biol (1984) 1.73
Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule. Mol Cell Biol (1985) 1.72
Different forms of simian virus 40 large tumor antigen varying in their affinities for DNA. J Virol (1982) 1.72
Expression and complex formation of simian virus 40 large T antigen and mouse p53 in insect cells. J Virol (1988) 1.72
Discrete regions of simian virus 40 large T antigen are required for nonspecific and viral origin-specific DNA binding. J Virol (1982) 1.71
Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter. J Cell Biol (1992) 1.70
Monoclonal antibodies as probes for a function of large T antigen during the elongation process of simian virus 40 DNA replication. J Virol (1987) 1.67
Mutations in p53 as potential molecular markers for human breast cancer. Proc Natl Acad Sci U S A (1991) 1.65
DNA-binding region of the simian virus 40 tumor antigen. J Virol (1986) 1.62
Acylated simian virus 40 large T-antigen: a new subclass associated with a detergent-resistant lamina of the plasma membrane. EMBO J (1983) 1.55
Initiation of simian virus 40 DNA replication requires the interaction of a specific domain of human DNA polymerase alpha with large T antigen. Mol Cell Biol (1993) 1.54
Inhibition of p53 DNA binding by human papillomavirus E6 proteins. J Virol (1994) 1.54
A mutation in SNAP29, coding for a SNARE protein involved in intracellular trafficking, causes a novel neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma. Am J Hum Genet (2005) 1.51
Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector. J Virol (1990) 1.51
Time-dependent maturation of the simian virus 40 large T antigen-p53 complex studied by using monoclonal antibodies. J Virol (1982) 1.50
Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line. J Cell Biol (1989) 1.48
Monoclonal antibodies against simian virus 40 tumor antigens: analysis of antigenic binding sites, using adenovirus type 2-simian virus 40 hybrid viruses. J Virol (1981) 1.44
Phosphorylation patterns of tumour antigens in cells lytically infected or transformed by simian virus 40. J Virol (1981) 1.42
Large T-antigen double hexamers imaged at the simian virus 40 origin of replication. Mol Cell Biol (2000) 1.42
Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest. Mol Cell Biol (1991) 1.39
Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation. J Virol (1989) 1.36
Simian virus 40 large T antigen stably complexes with a 185-kilodalton host protein. J Virol (1992) 1.35
Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen. J Exp Med (1994) 1.34
Negative regulation of Rb expression by the p53 gene product. Proc Natl Acad Sci U S A (1992) 1.33
Ataxia telangiectasia-mutated damage-signaling kinase- and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in Simian virus 40-infected primate cells. J Virol (2008) 1.32
Quantitation of a 55K cellular protein: similar amount and instability in normal and malignant mouse cells. Mol Cell Biol (1982) 1.30
Expression of the mouse p53 cellular tumor antigen in monkey cells. Mol Cell Biol (1984) 1.30
p53 transformation-related protein: detection of an associated phosphotransferase activity. Proc Natl Acad Sci U S A (1981) 1.30
mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol (2002) 1.28
DNA polymerase alpha from the nuclear matrix of cells infected with simian virus 40. Nucleic Acids Res (1982) 1.27
Stabilization of the 53,000-dalton nonviral tumor antigen is not required for transformation by simian virus 40. Mol Cell Biol (1983) 1.26
Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen. Mol Cell Biol (1994) 1.26
A second domain of simian virus 40 T antigen in which mutations can alter the cellular localization of the antigen. Mol Cell Biol (1986) 1.25
Modulation of p53 protein expression during cellular transformation with simian virus 40. Mol Cell Biol (1987) 1.25
Species-specific functional interactions of DNA polymerase alpha-primase with simian virus 40 (SV40) T antigen require SV40 origin DNA. Mol Cell Biol (1994) 1.24
Use of simian virus 40 large T-beta-galactosidase fusion proteins in an immunochemical analysis of simian virus 40 large T antigen. J Virol (1985) 1.23
Unwinding of chromatin by the SV40 large T antigen DNA helicase. EMBO J (1995) 1.23
The amino-terminal functions of the simian virus 40 large T antigen are required to overcome wild-type p53-mediated growth arrest of cells. J Virol (1994) 1.22
Increased expression of p53 protein in human leukemia cells. Proc Natl Acad Sci U S A (1986) 1.21
Abelson murine leukemia virus-transformed cells that lack p53 protein synthesis express aberrant p53 mRNA species. Mol Cell Biol (1984) 1.21
Evidence for allosteric variants of wild-type p53, a tumour suppressor protein. Br J Cancer (1990) 1.21
Evidence for free and metabolically stable p53 protein in nuclear subfractions of simian virus 40-transformed cells. Mol Cell Biol (1986) 1.20
Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant. Mol Cell Biol (1993) 1.20
Phosphorylation sites in the amino-terminal region of mouse p53. Proc Natl Acad Sci U S A (1992) 1.18
Uniform nomenclature for monoclonal antibodies directed against virus-coded proteins of simian virus 40 and polyoma virus. J Virol (1982) 1.18
The replication protein A binding site in simian virus 40 (SV40) T antigen and its role in the initial steps of SV40 DNA replication. J Virol (1998) 1.18
Human embryonic kidney cells: stable transformation with an origin-defective simian virus 40 DNA and use as hosts for human papovavirus replication. Mol Cell Biol (1984) 1.16
Purification and partial amino acid sequence analysis of the cellular tumour antigen, p53, from mouse SV40-transformed cells. EMBO J (1983) 1.16
Chromosomal assignment of the murine gene encoding the transformation-related protein p53. Mol Cell Biol (1984) 1.14
Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA. Proc Natl Acad Sci U S A (1988) 1.14
Association between the cellular p53 and the adenovirus 5 E1B-55kd proteins reduces the oncogenicity of Ad-transformed cells. EMBO J (1990) 1.12
Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53. Nucleic Acids Res (1992) 1.12
Permanent expression of p53 in FR 3T3 rat cells but cell cycle-dependent association with large-T antigen in simian virus 40 transformants. EMBO J (1985) 1.10
Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40. Proc Natl Acad Sci U S A (1981) 1.09
Monoclonal antibody to simian virus 40 small t. J Virol (1984) 1.08
Nonspecific DNA binding activity of simian virus 40 large T antigen: evidence for the cooperation of two regions for full activity. J Virol (1992) 1.07
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Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell (1979) 14.05
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Regulation of tumor antigen synthesis by simain virus 40 gene A. J Virol (1975) 9.93
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Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse. Proc Natl Acad Sci U S A (1979) 6.93
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Role of simian virus 40 gene A function in maintenance of transformation. J Virol (1975) 6.63
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Simian virus 40 gene A function and maintenance of transformation. J Virol (1975) 6.40
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The SV40 A gene product is required for the production of a 54,000 MW cellular tumor antigen. Virology (1979) 3.33
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Characterization of different tumor antigens present in cells transformed by simian virus 40. Cell (1979) 3.26
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Somatic cell hybrids producing antibodies specific for the tumor antigen of simian virus 40. Proc Natl Acad Sci U S A (1978) 2.47
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Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA. J Mol Biol (1974) 2.14
Subcellular Localization of simian virus 40 large tumor antigen. J Virol (1979) 2.03
Partial purification and characterization of the SV40 T antigen. Cell (1974) 1.81
Effect of alkylation on the physical properties of simian virus 40 T-antigen species. J Virol (1979) 1.77
Measurements of the molecular size of the simian virus 40 large T antigen. J Virol (1978) 1.70
Nucleotide sequence of the BK virus DNA segment encoding small t antigen. Proc Natl Acad Sci U S A (1979) 1.67
Characterization of the complex between SV40 large T antigen and the 53K host protein in transformed mouse cells. Cold Spring Harb Symp Quant Biol (1980) 1.26
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SV40 T-antigen-related molecules on the surfaces of HeLa cells infected with adenovirus-2-SV40 hybrids and on SV40-transformed cells. Cold Spring Harb Symp Quant Biol (1980) 1.14
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Time-dependent maturation of the simian virus 40 large T antigen-p53 complex studied by using monoclonal antibodies. J Virol (1982) 1.50
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