Cooperative assembly of simian virus 40 T-antigen hexamers on functional halves of the replication origin.

PubWeight™: 1.78‹?› | Rank: Top 3%

🔗 View Article (PMC 240896)

Published in J Virol on June 01, 1991

Authors

R E Parsons1, J E Stenger, S Ray, R Welker, M E Anderson, P Tegtmeyer

Author Affiliations

1: Department of Microbiology, State University of New York, Stony Brook 11794-8621.

Articles citing this

The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators. Proc Natl Acad Sci U S A (1995) 2.65

Carboxy terminus of human herpesvirus 8 latency-associated nuclear antigen mediates dimerization, transcriptional repression, and targeting to nuclear bodies. J Virol (2000) 1.96

Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication. Mol Cell Biol (1992) 1.76

DNA-binding domain of bovine papillomavirus type 1 E1 helicase: structural and functional aspects. J Virol (1993) 1.73

The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication. EMBO J (1993) 1.61

Two regions of simian virus 40 T antigen determine cooperativity of double-hexamer assembly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding. J Virol (1999) 1.43

Dimerization of simian virus 40 T-antigen hexamers activates T-antigen DNA helicase activity. J Virol (1997) 1.36

EBNA1 distorts oriP, the Epstein-Barr virus latent replication origin. J Virol (1992) 1.34

Bovine papillomavirus E1 protein binds specifically DNA polymerase alpha but not replication protein A. J Virol (1995) 1.33

Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding. J Virol (1993) 1.30

Strand and face: the topography of interactions between the SV40 origin of replication and T-antigen during the initiation of replication. EMBO J (1994) 1.28

Mechanism of activation of simian virus 40 DNA replication by protein phosphatase 2A. Mol Cell Biol (1992) 1.27

Assembly of T-antigen double hexamers on the simian virus 40 core origin requires only a subset of the available binding sites. Mol Cell Biol (1998) 1.25

Species-specific functional interactions of DNA polymerase alpha-primase with simian virus 40 (SV40) T antigen require SV40 origin DNA. Mol Cell Biol (1994) 1.24

Biochemical activities of minute virus of mice nonstructural protein NS1 are modulated In vitro by the phosphorylation state of the polypeptide. J Virol (1998) 1.23

The DNA-binding domain of simian virus 40 tumor antigen has multiple functions. J Virol (1993) 1.22

The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting. J Virol (1991) 1.16

cdc2 phosphorylation of threonine 124 activates the origin-unwinding functions of simian virus 40 T antigen. J Virol (1993) 1.15

Purification of the simian virus 40 (SV40) T antigen DNA-binding domain and characterization of its interactions with the SV40 origin. J Virol (1997) 1.15

The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. PLoS Biol (2007) 1.12

E1 recognition sequences in the bovine papillomavirus type 1 origin of DNA replication: interaction between half sites of the inverted repeats. J Virol (1995) 1.11

Inhibition of structural changes in the simian virus 40 core origin of replication by mutation of essential origin sequences. J Virol (1992) 1.09

Control of simian virus 40 DNA replication by the HeLa cell nuclear kinase casein kinase I. Mol Cell Biol (1993) 1.09

Mechanisms of simian virus 40 T-antigen activation by phosphorylation of threonine 124. J Virol (1996) 1.08

Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA. EMBO J (2006) 1.07

Biochemical analysis of mutants with changes in the origin-binding domain of simian virus 40 tumor antigen. J Virol (1993) 1.06

Interactions required for binding of simian virus 40 T antigen to the viral origin and molecular modeling of initial assembly events. J Virol (2004) 1.02

Spacing is crucial for coordination of domain functions within the simian virus 40 core origin of replication. J Virol (1992) 0.99

Phosphorylation of simian virus 40 T antigen on Thr 124 selectively promotes double-hexamer formation on subfragments of the viral core origin. J Virol (2000) 0.98

The simian virus 40 core origin contains two separate sequence modules that support T-antigen double-hexamer assembly. J Virol (2000) 0.98

The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting. J Virol (1997) 0.96

Sequence requirements for the assembly of simian virus 40 T antigen and the T-antigen origin binding domain on the viral core origin of replication. J Virol (1999) 0.95

trans-Dominant and non-trans-dominant mutant simian virus 40 large T antigens show distinct responses to ATP. J Virol (1997) 0.92

Topoisomerase I associates specifically with simian virus 40 large-T-antigen double hexamer-origin complexes. J Virol (2000) 0.91

Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigen. J Virol (1992) 0.90

Sequences flanking the pentanucleotide T-antigen binding sites in the polyomavirus core origin help determine selectivity of DNA replication. J Virol (1995) 0.88

A cell-free replication system for human polyomavirus JC DNA. J Virol (1997) 0.87

Structures of large T antigen at the origin of SV40 DNA replication by atomic force microscopy. Biophys J (1994) 0.87

Interaction of the transcription factor TFIID with simian virus 40 (SV40) large T antigen interferes with replication of SV40 DNA in vitro. J Virol (1999) 0.87

Determination of the origin-specific DNA-binding domain of polyomavirus large T antigen. J Virol (1991) 0.86

Simian virus 40 DNA replication is dependent on an interaction between topoisomerase I and the C-terminal end of T antigen. J Virol (2007) 0.82

A DNA-binding activity in BPV initiator protein E1 required for melting duplex ori DNA but not processive helicase activity initiated on partially single-stranded DNA. Nucleic Acids Res (2008) 0.81

Mechanisms of interference with simian virus 40 (SV40) DNA replication by trans-dominant mutants of SV40 large T antigen. J Virol (1992) 0.80

Two conditional tsA mutant simian virus 40 T antigens display marked differences in thermal inactivation. J Virol (1992) 0.80

Polyomavirus large T antigen binds cooperatively to its multiple binding sites in the viral origin of DNA replication. J Virol (1998) 0.80

Conformational changes in simian virus 40 rearranged regulatory regions: effects of the 21-base-pair promoters and their location. J Virol (1999) 0.79

Role of the hydrophilic channels of simian virus 40 T-antigen helicase in DNA replication. J Virol (2007) 0.79

Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner. J Virol (2013) 0.79

Topoisomerase activity is associated with purified SV40 T antigen. Nucleic Acids Res (1993) 0.77

Replication of simian virus 40 origin-containing DNA during infection with a recombinant Autographa californica multiple nuclear polyhedrosis virus expressing large T antigen. J Virol (1997) 0.77

Relationship among location of T-antigen-induced DNA distortion, auxiliary sequences, and DNA replication efficiency. J Virol (2003) 0.75

Murine p53 inhibits the function but not the formation of SV40 T antigen hexamers and stimulates T antigen RNA helicase activity. Chromosoma (1992) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels. Anal Biochem (1980) 24.76

Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon. J Virol (1972) 16.59

Simian virus 40 DNA replication in vitro. Proc Natl Acad Sci U S A (1984) 7.76

Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells. Mol Cell Biol (1985) 5.83

Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication. J Virol (1983) 5.00

An immunoaffinity purification procedure for SV40 large T antigen. Virology (1985) 4.81

Binding and unwinding--how T antigen engages the SV40 origin of DNA replication. Cell (1990) 4.65

ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication. Nature (1989) 4.64

Specific origin in SV40 DNA replication. Nat New Biol (1972) 4.39

Localized melting and structural changes in the SV40 origin of replication induced by T-antigen. EMBO J (1988) 3.96

Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J Virol (1986) 3.15

Domain structure of the simian virus 40 core origin of replication. Mol Cell Biol (1986) 2.72

ATP stimulates the binding of simian virus 40 (SV40) large tumor antigen to the SV40 origin of replication. Proc Natl Acad Sci U S A (1988) 2.51

ATP enhances the binding of simian virus 40 large T antigen to the origin of replication. J Virol (1987) 2.43

The adenine-thymine domain of the simian virus 40 core origin directs DNA bending and coordinately regulates DNA replication. Mol Cell Biol (1986) 2.31

DNA binding properties of simian virus 40 temperature-sensitive A proteins. J Virol (1982) 2.31

Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen. J Virol (1990) 2.24

Rapid "footprinting" on supercoiled DNA. Proc Natl Acad Sci U S A (1985) 2.21

Simian virus 40 large T antigen DNA helicase. Characterization of the ATPase-dependent DNA unwinding activity and its substrate requirements. J Biol Chem (1988) 2.10

Alternative interactions of the SV40 A protein with DNA. Virology (1981) 2.09

The T-antigen-binding domain of the simian virus 40 core origin of replication. J Virol (1987) 2.08

Expression of simian virus 40 T antigen in insect cells using a baculovirus expression vector. Virology (1988) 2.07

Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitro. Proc Natl Acad Sci U S A (1987) 1.89

Sequence-specific binding of simian virus 40 A protein to nonorigin and cellular DNA. Mol Cell Biol (1984) 1.68

Simian virus 40 mutant T antigens with relaxed specificity for the nucleotide sequence at the viral DNA origin of replication. J Virol (1984) 1.65

Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation. Mol Cell Biol (1989) 1.61

Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution. Proc Natl Acad Sci U S A (1985) 1.59

Articles by these authors

Simian virus 40 deoxyribonucleic acid synthesis: the viral replicon. J Virol (1972) 16.59

Glutathione. Annu Rev Biochem (1983) 15.18

Regulation of tumor antigen synthesis by simain virus 40 gene A. J Virol (1975) 9.93

Function of simian virus 40 gene A in transforming infection. J Virol (1975) 8.09

Temperature-sensitive mutants of simian virus 40: infection of permissive cells. J Virol (1971) 7.95

Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol (1985) 7.45

Organization and expression of early genes of simian virus 40. Proc Natl Acad Sci U S A (1978) 7.10

Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet (2001) 6.36

Inactivating and mutagenic effects of nitrosoguanidine on simian virus 40. Proc Natl Acad Sci U S A (1970) 5.46

Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication. J Virol (1983) 5.00

Identification of simian virus 40 protein A. J Virol (1977) 4.93

CoREST: a functional corepressor required for regulation of neural-specific gene expression. Proc Natl Acad Sci U S A (1999) 4.59

Relationship of replication and transcription of Simian Virus 40 DNA. Proc Natl Acad Sci U S A (1973) 4.35

Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2. Proc Natl Acad Sci U S A (2000) 4.31

Altered patterns of protein synthesis in infection by SV40 mutants. Cold Spring Harb Symp Quant Biol (1975) 4.30

Regulation of neuronal traits by a novel transcriptional complex. Neuron (2001) 4.02

Modification of simian virus 40 protein A. J Virol (1977) 3.79

The Florida "truth" anti-tobacco media evaluation: design, first year results, and implications for planning future state media evaluations. Tob Control (2001) 3.69

Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase. Science (1991) 3.27

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis. Proc Natl Acad Sci U S A (1992) 3.22

Functional interactions of the simian virus 40 core origin of replication with flanking regulatory sequences. J Virol (1986) 3.15

Influence of a counteradvertising media campaign on initiation of smoking: the Florida "truth" campaign. Am J Public Health (2001) 3.09

The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1995) 2.95

An altered DNA conformation in origin region I is a determinant for the binding of SV40 large T antigen. Cell (1986) 2.88

Analysis of HIV particle formation using transient expression of subviral constructs in mammalian cells. Virology (1992) 2.88

Retracted Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol (2000) 2.86

Topography of simian virus 40 A protein-DNA complexes: arrangement of protein bound to the origin of replication. J Virol (1983) 2.79

p53 domains: identification and characterization of two autonomous DNA-binding regions. Genes Dev (1993) 2.74

Domain structure of the simian virus 40 core origin of replication. Mol Cell Biol (1986) 2.72

Proposal for a uniform nomenclature for simian virus 40 mutants. J Virol (1972) 2.55

ATP enhances the binding of simian virus 40 large T antigen to the origin of replication. J Virol (1987) 2.43

Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene (2011) 2.36

Organization of immature human immunodeficiency virus type 1. J Virol (2001) 2.34

The adenine-thymine domain of the simian virus 40 core origin directs DNA bending and coordinately regulates DNA replication. Mol Cell Biol (1986) 2.31

Simian virus 40 deoxyribonucleic acid synthesis: analysis by gel electrophoresis. J Virol (1972) 2.31

DNA binding properties of simian virus 40 temperature-sensitive A proteins. J Virol (1982) 2.31

SHORT INTEGUMENT (SIN1), a gene required for ovule development in Arabidopsis, also controls flowering time. Development (1996) 2.28

Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen. J Virol (1990) 2.24

Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens. Proc Natl Acad Sci U S A (1990) 2.22

Crystal structure of the ectodomain of human transferrin receptor. Science (1999) 2.19

The industry manipulation attitudes of smokers and nonsmokers. J Public Health Manag Pract (2000) 2.14

Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase. J Biol Chem (1993) 2.13

Alternative interactions of the SV40 A protein with DNA. Virology (1981) 2.09

The T-antigen-binding domain of the simian virus 40 core origin of replication. J Virol (1987) 2.08

Using the UK primary care Quality and Outcomes Framework to audit health care equity: preliminary data on diabetes management. J Public Health (Oxf) (2006) 2.02

Inverted Alu repeats unstable in yeast are excluded from the human genome. EMBO J (2000) 2.01

Synthesis and assembly of simian virus 40. II. Synthesis of the major capsid protein and its incorporation into viral particles. J Virol (1972) 2.01

Arabidopsis floral homeotic gene BELL (BEL1) controls ovule development through negative regulation of AGAMOUS gene (AG). Proc Natl Acad Sci U S A (1994) 1.94

Altered protein metabolism in infection by the late tsB11 mutant of simian virus 40. J Virol (1974) 1.94

Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of gamma-glutamylcysteine synthetase. J Biol Chem (1979) 1.91

Role of cysteine residues in regulation of p53 function. Mol Cell Biol (1995) 1.91

Simian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitro. Proc Natl Acad Sci U S A (1987) 1.89

Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione. Arch Biochem Biophys (1985) 1.82

A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children. J Clin Invest (2000) 1.81

Use of a low-literacy patient education tool to enhance pneumococcal vaccination rates. A randomized controlled trial. JAMA (1999) 1.79

Urinary tract infections due to Staphylococcus saprophyticus biotype 3. Can Med Assoc J (1981) 1.75

Sequence-specific binding of simian virus 40 A protein to nonorigin and cellular DNA. Mol Cell Biol (1984) 1.68

p53 domains: structure, oligomerization, and transformation. Mol Cell Biol (1994) 1.68

Formation of stable p53 homotetramers and multiples of tetramers. Mol Carcinog (1992) 1.68

Intracellular transport of retroviral capsid components. Curr Top Microbiol Immunol (1996) 1.67

sin 1, a mutation affecting female fertility in Arabidopsis, interacts with mod 1, its recessive modifier. Genetics (1994) 1.66

An active-site mutation in the human immunodeficiency virus type 1 proteinase (PR) causes reduced PR activity and loss of PR-mediated cytotoxicity without apparent effect on virus maturation and infectivity. J Virol (1995) 1.65

Seventeen base pairs of region I encode a novel tripartite binding signal for SV40 T antigen. Cell (1985) 1.64

CaM kinase augments cardiac L-type Ca2+ current: a cellular mechanism for long Q-T arrhythmias. Am J Physiol (1999) 1.62

The effects of movement velocity, mass displaced, and task certainty on associated postural adjustments made by normal and hemiplegic individuals. J Neurol Neurosurg Psychiatry (1984) 1.62

Herpes simplex virus origin-binding protein (UL9) loops and distorts the viral replication origin. J Virol (1991) 1.62

Determinants for calmodulin binding on voltage-dependent Ca2+ channels. J Biol Chem (2000) 1.61

Pause-dependent polymorphic ventricular tachycardia during long-term treatment with dofetilide: a placebo-controlled, implantable cardioverter-defibrillator-based evaluation. J Am Coll Cardiol (2001) 1.60

Monomers through trimers of large tumor antigen bind in region I and monomers through tetramers bind in region II of simian virus 40 origin of replication DNA as stable structures in solution. Proc Natl Acad Sci U S A (1985) 1.59

HIV seroincidence and correlates of seroconversion in a cohort of male factory workers in Harare, Zimbabwe. AIDS (1996) 1.57

p53 oligomerization and DNA looping are linked with transcriptional activation. EMBO J (1994) 1.57

Pharmacokinetics of 18F-labeled fluconazole in healthy human subjects by positron emission tomography. Antimicrob Agents Chemother (1993) 1.55

Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system. Circ Res (1999) 1.55

Feline herpesvirus infection in fused cultures of naturally resistant human cells. J Virol (1969) 1.52

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation. Proc Natl Acad Sci U S A (1995) 1.52

Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma-glutamyl amino acids. Proc Natl Acad Sci U S A (1982) 1.52

Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase. J Biol Chem (1993) 1.52

Partial purification of SV40 A protein and a related cellular protein from permissive cells. Virology (1981) 1.51

Speckle tracking for multi-dimensional flow estimation. Ultrasonics (2000) 1.50

Breast conserving surgery for breast cancer: single institutional experience from Southern India. Indian J Cancer (2012) 1.50

Critical spatial requirement within the origin of simian virus 40 DNA replication. J Virol (1984) 1.49

Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding. J Virol (1990) 1.48

The zinc finger region of simian virus 40 large T antigen. J Virol (1989) 1.47

Replication but not transcription of simian virus 40 DNA is dependent on nuclear domain 10. J Virol (2000) 1.46

Should fewer premature infants be screened for retinopathy of prematurity in the managed care era? Pediatrics (1998) 1.45

Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis. Proc Natl Acad Sci U S A (1983) 1.45

Glutathione, a first line of defense against cadmium toxicity. FASEB J (1987) 1.44

Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Proc Natl Acad Sci U S A (1991) 1.40

Interaction of p53 with its consensus DNA-binding site. Mol Cell Biol (1995) 1.40

Atrial natriuretic peptide after acute myocardial infarction. Am Heart J (1990) 1.39

Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein. J Virol (1988) 1.39

Post-traumatic pelvic pseudoaneurysm and arterio-venous fistula: combined endovascular and surgical approach. Eur J Vasc Endovasc Surg (2008) 1.36