Published in J Physiol on December 08, 2005
CRAC channelopathies. Pflugers Arch (2010) 1.71
Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients. PLoS One (2012) 1.18
Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs. PLoS One (2008) 1.13
Molecular targets of aspirin and cancer prevention. Br J Cancer (2014) 1.09
Irvalec inserts into the plasma membrane causing rapid loss of integrity and necrotic cell death in tumor cells. PLoS One (2011) 0.88
Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid. J Agric Food Chem (2008) 0.88
A reciprocal shift in transient receptor potential channel 1 (TRPC1) and stromal interaction molecule 2 (STIM2) contributes to Ca2+ remodeling and cancer hallmarks in colorectal carcinoma cells. J Biol Chem (2014) 0.85
Oleic acid inhibits store-operated calcium entry in human colorectal adenocarcinoma cells. Eur J Nutr (2011) 0.83
Fus1/Tusc2 is a novel regulator of mitochondrial calcium handling, Ca2+-coupled mitochondrial processes, and Ca2+-dependent NFAT and NF-κB pathways in CD4+ T cells. Antioxid Redox Signal (2014) 0.82
Mitochondrial genetics and obesity: evolutionary adaptation and contemporary disease susceptibility. Free Radic Biol Med (2013) 0.79
Hitting the Bull's-Eye in Metastatic Cancers-NSAIDs Elevate ROS in Mitochondria, Inducing Malignant Cell Death. Pharmaceuticals (Basel) (2015) 0.79
CBARA1 plays a role in stemness and proliferation of human embryonic stem cells. PLoS One (2013) 0.78
Impact of acetylsalicylic Acid on the clinicopathological characteristics and prognosis of patients with invasive breast cancer. Breast Care (Basel) (2014) 0.75
Delphinidin Reduces Glucose Uptake in Mice Jejunal Tissue and Human Intestinal Cells Lines through FFA1/GPR40. Int J Mol Sci (2017) 0.75
Systems psychopharmacology: A network approach to developing novel therapies. World J Psychiatry (2016) 0.75
Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca(2+) responses, and neuron cell death in cultured rat hippocampal neurons. J Neuroinflammation (2017) 0.75
Effect of oleic acid on store-operated calcium entry in immune-competent cells. Eur J Nutr (2016) 0.75
Mitochondria sustain store-operated currents in colon cancer cells but not in normal colonic cells: reversal by non-steroidal anti-inflammatory drugs. Oncotarget (2017) 0.75
Observations on the carbohydrate metabolism of tumours. Biochem J (1929) 33.77
A model for receptor-regulated calcium entry. Cell Calcium (1986) 12.47
Store-operated calcium channels. Physiol Rev (2005) 11.95
A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med (2003) 9.18
Store depletion and calcium influx. Physiol Rev (1997) 7.15
Calcium signaling mechanisms in T lymphocytes. Annu Rev Immunol (2001) 7.06
A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. N Engl J Med (2003) 6.99
The mitochondrial calcium uniporter is a highly selective ion channel. Nature (2004) 6.97
Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiol Rev (1999) 6.30
Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion. Nat Cell Biol (2000) 3.22
Mitochondrial regulation of store-operated calcium signaling in T lymphocytes. J Cell Biol (1997) 3.04
Mitochondria are morphologically and functionally heterogeneous within cells. EMBO J (2002) 2.97
Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochem Pharmacol (1996) 2.87
Regulation of cell cycle progression by calcium/calmodulin-dependent pathways. Endocr Rev (2003) 2.47
Mitochondria as all-round players of the calcium game. J Physiol (2000) 2.47
Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol (2001) 2.35
Calcium signalling and cell proliferation. Bioessays (1995) 1.95
Mitochondrial control of calcium-channel gating: a mechanism for sustained signaling and transcriptional activation in T lymphocytes. Proc Natl Acad Sci U S A (2000) 1.92
Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2. J Biol Chem (2004) 1.88
Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs. Cancer Res (1999) 1.86
Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1. J Biol Chem (2004) 1.84
Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling. J Biol Chem (2003) 1.71
Agonist-induced Ca2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores. Biochem J (1991) 1.62
Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate. Proc Natl Acad Sci U S A (1999) 1.60
Alteration in temporal kinetics of Ca2+ signaling and control of growth and proliferation. Biol Cell (2004) 1.53
An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J Biol Chem (2000) 1.52
The effect of salicylate on the metabolism of normal and stimulated human lymphocytes in vitro. J Clin Invest (1971) 1.50
Store-operated Ca2+ entry depends on mitochondrial Ca2+ uptake. EMBO J (2002) 1.42
Respiring mitochondria determine the pattern of activation and inactivation of the store-operated Ca(2+) current I(CRAC). EMBO J (2000) 1.40
Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1. Mol Cell (2002) 1.32
Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2. J Biol Chem (2005) 1.30
Store-operated Ca2+ entry: dynamic interplay between endoplasmic reticulum, mitochondria and plasma membrane. J Physiol (2003) 1.29
The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action. Eur J Cancer (2000) 1.28
Energized mitochondria increase the dynamic range over which inositol 1,4,5-trisphosphate activates store-operated calcium influx. EMBO J (2001) 1.19
Salicylates and proton transport through lipid bilayer membranes: a model for salicylate-induced uncoupling and swelling in mitochondria. J Membr Biol (1990) 1.10
Uptake of Ca2+ and refilling of intracellular Ca2+ stores in Ehrlich-ascites-tumour cells and in rat thymocytes. Biochem J (1990) 1.08
Mitochondrial localization as a determinant of capacitative Ca2+ entry in HeLa cells. Cell Calcium (2004) 1.03
Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells. FASEB J (2002) 1.02
Aspirin and cancer risk: an update to 2001. Eur J Cancer Prev (2002) 0.99
Salicylic acid: a link between aspirin, diet and the prevention of colorectal cancer. QJM (2001) 0.99
Ruthenium-based compounds and tumour growth control (review). Int J Oncol (2000) 0.94
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling. Br J Pharmacol (2002) 0.91
The role of mitochondria in the regulation of calcium influx into Jurkat cells. Eur J Biochem (2000) 0.91
Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. Int J Cancer (2001) 0.90
Aspirin, non-steroidal anti-inflammatory drugs and colorectal neoplasia: future challenges in chemoprevention. Cancer Causes Control (2003) 0.90
A new pharmacological effect of salicylates: inhibition of NFAT-dependent transcription. J Immunol (2004) 0.90
Capacitative Ca2+ entry contributes to the Ca2+ influx induced by thyrotropin-releasing hormone (TRH) in GH3 pituitary cells. Pflugers Arch (1995) 0.88
Mitochondrial [Ca(2+)] oscillations driven by local high [Ca(2+)] domains generated by spontaneous electric activity. J Biol Chem (2001) 0.87
Sodium salicylate inhibits proliferation and induces G1 cell cycle arrest in human pancreatic cancer cell lines. J Gastrointest Surg (2000) 0.87
Suppression of human tumor cell proliferation through mitochondrial targeting. FASEB J (2002) 0.86
DNA array analysis of the effects of aspirin on colon cancer cells: involvement of Rac1. Carcinogenesis (2004) 0.85
Extracellular pH modifies mitochondrial control of capacitative calcium entry in Jurkat cells. J Biol Chem (2004) 0.84
Ca2+ influx induced by store release and cytosolic Ca2+ chelation in Ht29 colonic carcinoma cells. Pflugers Arch (1995) 0.84
Evidence for repressional role of an inverted CCAAT box in cell cycle-dependent transcription of the human DNA topoisomerase IIalpha gene. J Biol Chem (1999) 0.83
pH-dependent effect of mitochondria on calcium influx into Jurkat cells; a novel mechanism of cell protection against calcium entry during energy stress. Cell Calcium (2003) 0.81
Dynamics of stimulus-expression coupling as revealed by monitoring of prolactin promoter-driven reporter activity in individual, living mammotropes. Mol Endocrinol (1999) 0.81
Calcium signaling to nucleus via store-operated system during cell cycle in retinal neuroepithelium. Neurosci Res (2003) 0.80
Ca2+-independent secretion is dependent on cytoplasmic ATP in human platelets. FEBS Lett (1985) 0.80
Salicylates and vascular smooth muscle cell proliferation: molecular mechanisms for cell cycle arrest. Trends Cardiovasc Med (2001) 0.78
Agonist-induced Ca2+ influx in human neutrophils is not mediated by production of inositol polyphosphates but by emptying of the intracellular Ca2+ stores. Biochem Soc Trans (1994) 0.77
The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov (2012) 3.60
Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study. Transplantation (2011) 3.24
The IKK complex contributes to the induction of autophagy. EMBO J (2009) 2.41
Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway. Clin Cancer Res (2010) 2.29
miR-181a and miR-630 regulate cisplatin-induced cancer cell death. Cancer Res (2010) 2.24
Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity. Mol Cell (2012) 2.14
Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells. Cell Cycle (2010) 2.08
Autophagic removal of micronuclei. Cell Cycle (2012) 1.85
Chemotherapy induces ATP release from tumor cells. Cell Cycle (2009) 1.83
Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proc Natl Acad Sci U S A (2013) 1.73
Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction. Circ Res (2004) 1.65
Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos. EMBO J (2010) 1.64
Immunogenic cell death modalities and their impact on cancer treatment. Apoptosis (2009) 1.56
Trial watch: Dendritic cell-based interventions for cancer therapy. Oncoimmunology (2012) 1.51
Calcium signaling and exocytosis in adrenal chromaffin cells. Physiol Rev (2006) 1.48
Prognostic impact of vitamin B6 metabolism in lung cancer. Cell Rep (2012) 1.45
Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study. Transplantation (2013) 1.39
Trial watch: Chemotherapy with immunogenic cell death inducers. Oncoimmunology (2013) 1.31
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone. Cancer Res (2008) 1.29
Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation. EMBO J (2011) 1.24
Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway. PLoS One (2007) 1.23
Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention. Proc Natl Acad Sci U S A (2014) 1.22
Prevalence of infection with Toxoplasma gondii among pregnant women in Cali, Colombia, South America. Am J Trop Med Hyg (2008) 1.15
Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5. Cell Cycle (2009) 1.13
Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs. PLoS One (2008) 1.13
Surface-exposed calreticulin in the interaction between dying cells and phagocytes. Ann N Y Acad Sci (2010) 1.12
Viral subversion of immunogenic cell death. Cell Cycle (2009) 1.12
Cisplatin resistance associated with PARP hyperactivation. Cancer Res (2013) 1.11
Independent transcriptional reprogramming and apoptosis induction by cisplatin. Cell Cycle (2012) 1.07
Immunogenic cell death inducers as anticancer agents. Oncotarget (2014) 1.05
The endoplasmic reticulum of dorsal root ganglion neurons contains functional TRPV1 channels. J Biol Chem (2009) 1.04
Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial. Transplantation (2015) 1.04
Calcium influx through receptor-operated channel induces mitochondria-triggered paraptotic cell death. J Biol Chem (2003) 1.03
Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells. FASEB J (2002) 1.02
Functions of BCL-X L at the Interface between Cell Death and Metabolism. Int J Cell Biol (2013) 1.02
RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells. J Cell Biol (2008) 1.01
The sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) is the third element in capacitative calcium entry. Cell Calcium (2010) 0.98
Calcium microdomains in mitochondria and nucleus. Cell Calcium (2006) 0.97
The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. Nat Commun (2012) 0.96
Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells. Biochem Pharmacol (2009) 0.96
Calcium entry-calcium refilling (CECR) coupling between store-operated Ca(2+) entry and sarco/endoplasmic reticulum Ca(2+)-ATPase. Cell Calcium (2011) 0.95
Immunosurveillance against tetraploidization-induced colon tumorigenesis. Cell Cycle (2013) 0.94
Selective killing of p53-deficient cancer cells by SP600125. EMBO Mol Med (2012) 0.94
IKK connects autophagy to major stress pathways. Autophagy (2010) 0.92
Treatment of knee osteoarthritis with autologous mesenchymal stem cells: two-year follow-up results. Transplantation (2014) 0.92
Crosstalk between ER stress and immunogenic cell death. Cytokine Growth Factor Rev (2013) 0.91
Nuclear Ca(2+) signalling. Cell Calcium (2010) 0.91
Synergistic interaction between cisplatin and PARP inhibitors in non-small cell lung cancer. Cell Cycle (2013) 0.90
Regulation of mitochondrial permeability transition pore by PINK1. Mol Neurodegener (2012) 0.90
Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress. Biochem J (2011) 0.90
Bioluminescence imaging of mitochondrial Ca2+ dynamics in soma and neurites of individual adult mouse sympathetic neurons. J Physiol (2007) 0.90
Vitamin B6 metabolism influences the intracellular accumulation of cisplatin. Cell Cycle (2012) 0.89
Subcellular Ca(2+) Dynamics. News Physiol Sci (1999) 0.89
Prognostic value of LIPC in non-small cell lung carcinoma. Cell Cycle (2013) 0.88
Anterior pituitary thyrotropes are multifunctional cells. Am J Physiol Endocrinol Metab (2004) 0.88
Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells. Cell Cycle (2008) 0.87
Privileged coupling between Ca(2+) entry through plasma membrane store-operated Ca(2+) channels and the endoplasmic reticulum Ca(2+) pump. Mol Cell Endocrinol (2011) 0.87
Multifunctional cells of mouse anterior pituitary reveal a striking sexual dimorphism. J Physiol (2003) 0.87
Preferential killing of p53-deficient cancer cells by reversine. Cell Cycle (2012) 0.86
Red and green aequorins for simultaneous monitoring of Ca2+ signals from two different organelles. Pflugers Arch (2007) 0.86
Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy. Autophagy (2012) 0.85
Immunostimulatory activity of lifespan-extending agents. Aging (Albany NY) (2013) 0.85
The role of mitochondrial potential in control of calcium signals involved in cell proliferation. Cell Calcium (2008) 0.85
Changes in expression of hypothalamic releasing hormone receptors in individual rat anterior pituitary cells during maturation, puberty and senescence. Endocrinology (2005) 0.82
Susceptibility to excitotoxicity in aged hippocampal cultures and neuroprotection by non-steroidal anti-inflammatory drugs: role of mitochondrial calcium. J Neurochem (2015) 0.82
Multifunctional cells in human pituitary adenomas: implications for paradoxical secretion and tumorigenesis. J Clin Endocrinol Metab (2004) 0.82
Nuclear calcium signaling by inositol trisphosphate in GH3 pituitary cells. Cell Calcium (2007) 0.81
Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons. J Neurosci (2014) 0.81
Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets. Cell Calcium (2007) 0.81
Tetraploid cancer cell precursors in ovarian carcinoma. Cell Cycle (2012) 0.80
Rapid changes in anterior pituitary cell phenotypes in male and female mice after acute cold stress. Endocrinology (2008) 0.80
17beta-estradiol promotes cementoblast proliferation and cementum formation in experimental periodontitis. J Periodontol (2010) 0.80
Generation of inner ear sensory cells from bone marrow-derived human mesenchymal stem cells. Regen Med (2012) 0.80
Phenotypic characterization of multi-functional somatotropes, mammotropes and gonadotropes of the mouse anterior pituitary. Pflugers Arch (2004) 0.80
Effect of inositol 1,4,5-trisphosphate receptor stimulation on mitochondrial [Ca2+] and secretion in chromaffin cells. Biochem J (2002) 0.79
Cytofluorometric purification of diploid and tetraploid cancer cells. Methods Mol Biol (2011) 0.79
Immunosurveillance against cancer-associated hyperploidy. Oncotarget (2012) 0.79
Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse. Cell Calcium (2005) 0.79
Lepidopterism due to exposure to the moth Hylesia metabus in northeastern Venezuela. Am J Trop Med Hyg (2005) 0.79
Dampening of cytosolic Ca2+ oscillations on propagation to nucleus. J Biol Chem (2002) 0.79