Upregulated TRP and enhanced capacitative Ca(2+) entry in human pulmonary artery myocytes during proliferation.

PubWeight™: 2.35‹?› | Rank: Top 2%

🔗 View Article (PMID 11158974)

Published in Am J Physiol Heart Circ Physiol on February 01, 2001

Authors

V A Golovina1, O Platoshyn, C L Bailey, J Wang, A Limsuwan, M Sweeney, L J Rubin, J X Yuan

Author Affiliations

1: Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

Articles citing this

(truncated to the top 100)

Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 3.69

Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation (2010) 2.85

Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Proc Natl Acad Sci U S A (2004) 2.79

Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration. FASEB J (2009) 2.36

Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J (2008) 2.31

Upregulated TRPC1 channel in vascular injury in vivo and its role in human neointimal hyperplasia. Circ Res (2006) 2.22

A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension. Circulation (2009) 2.17

Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP. J Physiol (2004) 2.03

Ca2+ handling is altered when arterial myocytes progress from a contractile to a proliferative phenotype in culture. Am J Physiol Cell Physiol (2008) 2.01

The non-excitable smooth muscle: calcium signaling and phenotypic switching during vascular disease. Pflugers Arch (2008) 1.72

Multiple roles of calmodulin and other Ca(2+)-binding proteins in the functional regulation of TRP channels. Pflugers Arch (2005) 1.68

Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers. Cardiovasc Res (2010) 1.57

A Ca2+-permeable non-selective cation channel activated by depletion of internal Ca2+ stores in single rabbit portal vein myocytes. J Physiol (2002) 1.51

Visualization of localized store-operated calcium entry in mouse astrocytes. Close proximity to the endoplasmic reticulum. J Physiol (2005) 1.50

The developing relationship between receptor-operated and store-operated calcium channels in smooth muscle. Br J Pharmacol (2002) 1.50

Differences in STIM1 and TRPC expression in proximal and distal pulmonary arterial smooth muscle are associated with differences in Ca2+ responses to hypoxia. Am J Physiol Lung Cell Mol Physiol (2008) 1.42

Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cells. J Physiol (2007) 1.37

RNA interference targeting STIM1 suppresses vascular smooth muscle cell proliferation and neointima formation in the rat. Mol Ther (2008) 1.36

Activation of store-operated channels by noradrenaline via protein kinase C in rabbit portal vein myocytes. J Physiol (2002) 1.36

TRP channels in hypertension. Biochim Biophys Acta (2007) 1.25

Upregulation of Na+ and Ca2+ transporters in arterial smooth muscle from ouabain-induced hypertensive rats. Am J Physiol Heart Circ Physiol (2009) 1.24

New mechanisms of pulmonary arterial hypertension: role of Ca²⁺ signaling. Am J Physiol Heart Circ Physiol (2012) 1.24

Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease. Mol Biol Cell (2006) 1.17

Orai1, a critical component of store-operated Ca2+ entry, is functionally associated with Na+/Ca2+ exchanger and plasma membrane Ca2+ pump in proliferating human arterial myocytes. Am J Physiol Cell Physiol (2009) 1.17

Transient receptor potential channels in the vasculature. Physiol Rev (2015) 1.14

Mobilization of sarcoplasmic reticulum stores by hypoxia leads to consequent activation of capacitative Ca2+ entry in isolated canine pulmonary arterial smooth muscle cells. J Physiol (2004) 1.11

Store-operated calcium entry in vascular smooth muscle. Br J Pharmacol (2007) 1.11

Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling. Antioxid Redox Signal (2010) 1.09

Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation. Pflugers Arch (2008) 1.08

TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells. J Biol Chem (2005) 1.08

Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells. PLoS One (2012) 1.04

Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas. Cell Prolif (2008) 1.04

Pharmacological profile of store-operated channels in cerebral arteriolar smooth muscle cells. Br J Pharmacol (2003) 1.03

Contribution and regulation of TRPC channels in store-operated Ca2+ entry. Curr Top Membr (2013) 1.03

Function of a STIM1 homologue in C. elegans: evidence that store-operated Ca2+ entry is not essential for oscillatory Ca2+ signaling and ER Ca2+ homeostasis. J Gen Physiol (2006) 1.02

Vascular remodeling in pulmonary hypertension. J Mol Med (Berl) (2013) 1.02

Mitogenic modulation of Ca2+ -activated K+ channels in proliferating A7r5 vascular smooth muscle cells. Br J Pharmacol (2006) 1.02

Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2011) 1.01

Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate. J Physiol (2005) 1.00

Inhibition of SOC/Ca2+/NFAT pathway is involved in the anti-proliferative effect of sildenafil on pulmonary artery smooth muscle cells. Respir Res (2009) 1.00

TRPC channels in smooth muscle cells. Front Biosci (Landmark Ed) (2010) 1.00

Ca2+ signaling, intracellular pH and cell volume in cell proliferation. J Membr Biol (2005) 0.99

Disruption of transient receptor potential canonical channel 1 causes incomplete cytokinesis and slows the growth of human malignant gliomas. Glia (2010) 0.99

CRAC channel activity in C. elegans is mediated by Orai1 and STIM1 homologues and is essential for ovulation and fertility. J Physiol (2007) 0.99

Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2009) 0.99

Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension. Circ Res (2012) 0.99

STIM proteins: integrators of signalling pathways in development, differentiation and disease. J Cell Mol Med (2010) 0.97

Functional ion channels in human pulmonary artery smooth muscle cells: Voltage-dependent cation channels. Pulm Circ (2011) 0.96

Bone morphogenetic protein 4 enhances canonical transient receptor potential expression, store-operated Ca2+ entry, and basal [Ca2+]i in rat distal pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol (2010) 0.96

Enhanced store-operated Ca²+ entry and TRPC channel expression in pulmonary arteries of monocrotaline-induced pulmonary hypertensive rats. Am J Physiol Cell Physiol (2011) 0.95

Orai1 calcium channels in the vasculature. Pflugers Arch (2012) 0.95

Activity of Ca -activated Cl channels contributes to regulating receptor- and store-operated Ca entry in human pulmonary artery smooth muscle cells. Pulm Circ (2011) 0.94

Alpha1-adrenergic receptors activate Ca(2+)-permeable cationic channels in prostate cancer epithelial cells. J Clin Invest (2003) 0.93

Orai1 interacts with STIM1 and mediates capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol (2010) 0.92

Two types of non-selective cation channel opened by muscarinic stimulation with carbachol in bovine ciliary muscle cells. J Physiol (2004) 0.92

Interactions between calcium and reactive oxygen species in pulmonary arterial smooth muscle responses to hypoxia. Respir Physiol Neurobiol (2010) 0.91

Cell volume regulation in epithelial physiology and cancer. Front Physiol (2013) 0.90

Physiological roles of STIM1 and Orai1 homologs and CRAC channels in the genetic model organism Caenorhabditis elegans. Cell Calcium (2007) 0.89

Expression of store-operated Ca2+ entry and transient receptor potential canonical and vanilloid-related proteins in rat distal pulmonary venous smooth muscle. Am J Physiol Lung Cell Mol Physiol (2010) 0.89

Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol (2014) 0.88

Mechanisms of the prostaglandin F2alpha-induced rise in [Ca2+]i in rat intrapulmonary arteries. J Physiol (2005) 0.87

Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2014) 0.87

Peroxisome proliferator-activated receptor γ inhibits pulmonary hypertension targeting store-operated calcium entry. J Mol Med (Berl) (2014) 0.86

Prednisolone inhibits PDGF-induced nuclear translocation of NF-kappaB in human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2008) 0.86

BMP4 increases the expression of TRPC and basal [Ca2+]i via the p38MAPK and ERK1/2 pathways independent of BMPRII in PASMCs. PLoS One (2014) 0.86

Role of reactive oxygen species and redox in regulating the function of transient receptor potential channels. Antioxid Redox Signal (2011) 0.86

Regulation of ca(2+) signaling in pulmonary hypertension. Korean J Physiol Pharmacol (2013) 0.85

On the activation mechanism of store-operated calcium channels. Pflugers Arch (2006) 0.85

Tetramerization domain mutations in KCNA5 affect channel kinetics and cause abnormal trafficking patterns. Am J Physiol Cell Physiol (2009) 0.85

Regulation and function of Cav3.1 T-type calcium channels in IGF-I-stimulated pulmonary artery smooth muscle cells. Am J Physiol Cell Physiol (2010) 0.85

A reciprocal shift in transient receptor potential channel 1 (TRPC1) and stromal interaction molecule 2 (STIM2) contributes to Ca2+ remodeling and cancer hallmarks in colorectal carcinoma cells. J Biol Chem (2014) 0.85

Silencing of STIM1 attenuates hypoxia-induced PASMCs proliferation via inhibition of the SOC/Ca2+/NFAT pathway. Respir Res (2013) 0.84

Modulation of canonical transient receptor potential channel 1 in the proliferation of oligodendrocyte precursor cells by the golli products of the myelin basic protein gene. J Neurosci (2011) 0.84

Mutation of delta-sarcoglycan is associated with Ca(2+) -dependent vascular remodeling in the Syrian hamster. Am J Pathol (2007) 0.84

Evidence against reciprocal regulation of Ca2+ entry by vasopressin in A7r5 rat aortic smooth-muscle cells. Biochem J (2005) 0.84

Cellular functions of transient receptor potential channels. Int J Biochem Cell Biol (2010) 0.83

High altitude pulmonary hypertension: role of K+ and Ca2+ channels. High Alt Med Biol (2005) 0.83

Rat strain differences in pulmonary artery smooth muscle Ca(2+) entry following chronic hypoxia. Microcirculation (2009) 0.83

Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction. Am J Physiol Cell Physiol (2011) 0.83

Novel strategy for treatment of pulmonary arterial hypertension: enhancement of apoptosis. Lung (2010) 0.82

Effect of short-term organoid culture on the pharmaco-mechanical properties of rat extra- and intrapulmonary arteries. Br J Pharmacol (2005) 0.82

A process-based review of mouse models of pulmonary hypertension. Pulm Circ (2012) 0.82

Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am J Respir Cell Mol Biol (2015) 0.82

Effects of chronic exposure to cigarette smoke on canonical transient receptor potential expression in rat pulmonary arterial smooth muscle. Am J Physiol Cell Physiol (2013) 0.82

Acute hypoxia activates store-operated Ca(2+) entry and increases intracellular Ca(2+) concentration in rat distal pulmonary venous smooth muscle cells. J Thorac Dis (2013) 0.81

Bone morphogenetic protein 2 decreases TRPC expression, store-operated Ca(2+) entry, and basal [Ca(2+)]i in rat distal pulmonary arterial smooth muscle cells. Am J Physiol Cell Physiol (2013) 0.81

Endothelial and smooth muscle cell ion channels in pulmonary vasoconstriction and vascular remodeling. Compr Physiol (2011) 0.80

Protein kinases modulate store-operated channels in pulmonary artery smooth muscle cells. J Biomed Sci (2011) 0.80

Histamine-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells. Am J Physiol Cell Physiol (2005) 0.80

Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension. J Signal Transduct (2012) 0.79

55th Bowditch Lecture: Effects of chronic hypoxia on the pulmonary circulation: role of HIF-1. J Appl Physiol (1985) (2012) 0.79

Ca(2+) and ion channels in hypoxia-mediated pulmonary hypertension. Int J Clin Exp Pathol (2015) 0.78

Is resveratrol the magic bullet for pulmonary hypertension? Hypertension (2009) 0.77

Role of store-operated Ca(2+) entry in adenosine-induced vasodilatation of rat small mesenteric artery. Am J Physiol Heart Circ Physiol (2009) 0.77

Sex differences in the pulmonary circulation: implications for pulmonary hypertension. Am J Physiol Heart Circ Physiol (2014) 0.77

Store-operated Ca(2+) entry is not essential for PDGF-BB induced phenotype modulation in rat aortic smooth muscle. Cell Calcium (2010) 0.76

Molecular and functional significance of Ca(2+)-activated Cl(-) channels in pulmonary arterial smooth muscle. Pulm Circ (2015) 0.76

Effects of exogenous annexin-1 on lipopolysaccharide-induced proliferation and reactive oxygen species production partially through modulation of CRAC channels but independent of NF-kappaB pathway. Inflamm Res (2009) 0.76

Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling. PLoS One (2017) 0.75

NADPH oxidases-do they play a role in TRPC regulation under hypoxia? Pflugers Arch (2015) 0.75

Articles by these authors

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

The sequence of the human genome. Science (2001) 101.55

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics (2003) 32.92

Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia. Nature (2004) 16.76

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity (2000) 16.03

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science (1992) 14.70

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science (1995) 13.15

Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med (2001) 10.36

Avian flu: H5N1 virus outbreak in migratory waterfowl. Nature (2005) 10.04

Highly pathogenic H5N1 influenza virus infection in migratory birds. Science (2005) 9.64

Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci U S A (2006) 9.26

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest (1999) 8.38

A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med (1996) 8.02

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet (1998) 7.89

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet (2001) 6.88

Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry (2001) 6.75

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell (2000) 6.70

A global profile of germline gene expression in C. elegans. Mol Cell (2000) 5.97

Atomic structure of a thermostable subdomain of HIV-1 gp41. Proc Natl Acad Sci U S A (1997) 5.76

Preoperative chemotherapy in patients with operable breast cancer: nine-year results from National Surgical Adjuvant Breast and Bowel Project B-18. J Natl Cancer Inst Monogr (2001) 5.74

Structure of the replicating complex of a pol alpha family DNA polymerase. Cell (2001) 5.26

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J (2000) 5.22

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell (2001) 5.19

Indium phosphide nanowires as building blocks for nanoscale electronic and optoelectronic devices. Nature (2001) 5.09

Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial. Ann Oncol (2009) 5.08

Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol (1999) 4.97

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell (1998) 4.78

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J Exp Med (2001) 4.63

Emergence and predominance of an H5N1 influenza variant in China. Proc Natl Acad Sci U S A (2006) 4.49

Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions. J Comp Physiol A (1994) 4.24

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I. Proc Natl Acad Sci U S A (2000) 4.22

Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs. Science (2013) 4.17

Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med (2000) 4.07

Anthropogenic warming of Earth's climate system. Science (2001) 3.94

Effect of long-term estrogen deprivation on apoptotic responses of breast cancer cells to 17beta-estradiol. J Natl Cancer Inst (2001) 3.88

Detection of Norwalk virus in stool by polymerase chain reaction. J Clin Microbiol (1992) 3.82

Quantum annealing with manufactured spins. Nature (2011) 3.81

SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome. Nat Genet (1998) 3.79

Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J Clin Invest (1996) 3.74

Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin. Science (1999) 3.71

The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia (2008) 3.69

Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene (2009) 3.64

Chronic thromboembolic pulmonary hypertension. N Engl J Med (2001) 3.51

Multiferroic BaTiO3-CoFe2O4 Nanostructures. Science (2004) 3.49

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID). Nature (1990) 3.42

Rift Valley fever virus (family Bunyaviridae, genus Phlebovirus). Isolations from Diptera collected during an inter-epizootic period in Kenya. J Hyg (Lond) (1985) 3.39

Brain serotonin neurotoxicity and primary pulmonary hypertension from fenfluramine and dexfenfluramine. A systematic review of the evidence. JAMA (1997) 3.35

Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med (1996) 3.33

MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol Cell Biol (1995) 3.32

Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry. Am J Clin Nutr (1990) 3.24

The crystal structure of a T cell receptor in complex with peptide and MHC class II. Science (1999) 3.23

Environmental effects on photosynthesis, nitrogen-use efficiency, and metabolite pools in leaves of sun and shade plants. Plant Physiol (1987) 3.23

Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc Natl Acad Sci U S A (1999) 3.19

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution. EMBO J (1994) 3.18

The genesis and evolution of H9N2 influenza viruses in poultry from southern China, 2000 to 2005. J Virol (2007) 3.12

Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci (1999) 3.10

Prediction of body cell mass, fat-free mass, and total body water with bioelectrical impedance analysis: effects of race, sex, and disease. Am J Clin Nutr (1996) 3.06

Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide. J Gen Physiol (2001) 3.04

Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol (1999) 2.96

Quality of life (QoL) analyses from OPTIMAL (CTONG-0802), a phase III, randomised, open-label study of first-line erlotinib versus chemotherapy in patients with advanced EGFR mutation-positive non-small-cell lung cancer (NSCLC). Ann Oncol (2013) 2.92

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev (2000) 2.90

Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. Genes Dev (1992) 2.86

Enhanced tumor growth of both primary and established human and murine tumor cells in athymic mice after coinjection with Matrigel. J Natl Cancer Inst (1991) 2.86

Structure of Taq polymerase with DNA at the polymerase active site. Nature (1996) 2.84

Survival with first-line bosentan in patients with primary pulmonary hypertension. Eur Respir J (2005) 2.83

Adherence to statin treatment and readmission of patients after myocardial infarction: a six year follow up study. Heart (2002) 2.83

The 2.4 A crystal structure of the bacterial chaperonin GroEL complexed with ATP gamma S. Nat Struct Biol (1996) 2.81

Relation of BMI to fat and fat-free mass among children and adolescents. Int J Obes (Lond) (2005) 2.80

Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors. Proc Natl Acad Sci U S A (1998) 2.80

Micron-resolution ranging of cornea anterior chamber by optical reflectometry. Lasers Surg Med (1991) 2.80

Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. FASEB J (2001) 2.78

Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin. Ann Intern Med (1994) 2.75

Magnitude of body-cell-mass depletion and the timing of death from wasting in AIDS. Am J Clin Nutr (1989) 2.75

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1994) 2.71

Structure and cell cycle-regulated transcription of the human cyclin A gene. Proc Natl Acad Sci U S A (1994) 2.69

Development of calibrated viral load standards for group M subtypes of human immunodeficiency virus type 1 and performance of an improved AMPLICOR HIV-1 MONITOR test with isolates of diverse subtypes. J Clin Microbiol (1999) 2.68

Posterior component separation with transversus abdominis release successfully addresses recurrent ventral hernias following anterior component separation. Hernia (2014) 2.64

Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res (1994) 2.64

Epoprostenol for treatment of pulmonary hypertension in patients with systemic lupus erythematosus. Chest (2000) 2.64

Genetic relationships of penicillin-susceptible and -resistant Streptococcus pneumoniae strains isolated on different continents. Infect Immun (1992) 2.62

Crystal structure of Thermus aquaticus DNA polymerase. Nature (1995) 2.62

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol Cell Biol (2001) 2.58

Frizzled-related protein variants are risk factors for hip osteoarthritis. Arthritis Rheum (2006) 2.57

Cyclin A is required in S phase in normal epithelial cells. Biochem Biophys Res Commun (1992) 2.55

BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science (1999) 2.54

A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol. Proc Natl Acad Sci U S A (1997) 2.53

Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism. Nature (1997) 2.52

Primary pulmonary hypertension. Lancet (1998) 2.47

Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis. Infect Immun (1996) 2.43

Estimation of extracellular and total body water by multiple-frequency bioelectrical-impedance measurement. Am J Clin Nutr (1991) 2.42

Long-term outcome in pulmonary arterial hypertension patients treated with subcutaneous treprostinil. Eur Respir J (2006) 2.39

DNA looping by Ku and the DNA-dependent protein kinase. Proc Natl Acad Sci U S A (1997) 2.39

Blood-pressure lowering for the secondary prevention of stroke. Lancet (2001) 2.39

Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis. Arthritis Rheum (2010) 2.37

Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes. Blood (1995) 2.36

Human cytotoxic T-cell memory: long-lived responses to vaccinia virus. J Virol (1996) 2.35

Detection of Rift Valley fever viral activity in Kenya by satellite remote sensing imagery. Science (1987) 2.33

p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. J Biol Chem (2000) 2.31

Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone (2005) 2.30