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MEGAN analysis of metagenomic data. Genome Res (2007) 25.29

Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2006) 18.84

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The UCSC genome browser database: update 2007. Nucleic Acids Res (2006) 13.04

DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis. BMC Bioinformatics (2007) 12.76

EMBL Nucleotide Sequence Database in 2006. Nucleic Acids Res (2006) 9.72

Classical nuclear localization signals: definition, function, and interaction with importin alpha. J Biol Chem (2006) 5.34

EMBL Nucleotide Sequence Database: developments in 2005. Nucleic Acids Res (2006) 5.13

The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information. Database (Oxford) (2010) 4.66

Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation. Nucleic Acids Res (2006) 3.62

Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases. BMC Bioinformatics (2007) 3.44

REBASE--enzymes and genes for DNA restriction and modification. Nucleic Acids Res (2007) 3.44

Assembling a global database of malaria parasite prevalence for the Malaria Atlas Project. Malar J (2007) 3.42

Epistasis as the primary factor in molecular evolution. Nature (2012) 3.34

The mouse Gene Expression Database (GXD): 2007 update. Nucleic Acids Res (2006) 3.30

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Constraint and turnover in sex-biased gene expression in the genus Drosophila. Nature (2007) 3.04

A statistical phylogeography of influenza A H5N1. Proc Natl Acad Sci U S A (2007) 2.91

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A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis. Proc Natl Acad Sci U S A (2008) 2.23

CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novo gene prediction. Genome Biol (2007) 2.01

Centroid estimation in discrete high-dimensional spaces with applications in biology. Proc Natl Acad Sci U S A (2008) 1.90

Indexing strategies for rapid searches of short words in genome sequences. PLoS One (2007) 1.85

Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module. Proc Natl Acad Sci U S A (2007) 1.83

The ASAP II database: analysis and comparative genomics of alternative splicing in 15 animal species. Nucleic Acids Res (2006) 1.80

A primer on python for life science researchers. PLoS Comput Biol (2007) 1.78

An evaluation of LSU rDNA D1-D2 sequences for their use in species identification. Front Zool (2007) 1.75

Application of SmartGene IDNS software to partial 16S rRNA gene sequences for a diverse group of bacteria in a clinical laboratory. J Clin Microbiol (2006) 1.74

Comprehensive annotation of bidirectional promoters identifies co-regulation among breast and ovarian cancer genes. PLoS Comput Biol (2007) 1.69

Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns. PLoS Genet (2012) 1.68

Borrelia burgdorferi genetic markers and disseminated disease in patients with early Lyme disease. J Clin Microbiol (2006) 1.66

GenSeq: An updated nomenclature and ranking for genetic sequences from type and non-type sources. Zookeys (2013) 1.62

Heterogeneous genomic molecular clocks in primates. PLoS Genet (2006) 1.55

SYSTOMONAS--an integrated database for systems biology analysis of Pseudomonas. Nucleic Acids Res (2007) 1.55

Compensatory evolution in mitochondrial tRNAs navigates valleys of low fitness. Nature (2010) 1.49

Evolution of glyoxylate cycle enzymes in Metazoa: evidence of multiple horizontal transfer events and pseudogene formation. Biol Direct (2006) 1.49

Adaptations to submarine hydrothermal environments exemplified by the genome of Nautilia profundicola. PLoS Genet (2009) 1.48

Influenza A H5N1 immigration is filtered out at some international borders. PLoS One (2008) 1.46

Amino acid residue doublet propensity in the protein-RNA interface and its application to RNA interface prediction. Nucleic Acids Res (2006) 1.41

Achievements and new knowledge unraveled by metagenomic approaches. Appl Microbiol Biotechnol (2009) 1.39

Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3. PLoS One (2008) 1.38

Data sharing: how much doesn't get submitted to GenBank? PLoS Biol (2006) 1.37

Mutations of different molecular origins exhibit contrasting patterns of regional substitution rate variation. PLoS Comput Biol (2008) 1.35

DNA-based faecal dietary analysis: a comparison of qPCR and high throughput sequencing approaches. PLoS One (2011) 1.32

Evolution of the iron-responsive element. RNA (2007) 1.27

SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis. BMC Bioinformatics (2007) 1.25

Phaeobacter and Ruegeria species of the Roseobacter clade colonize separate niches in a Danish Turbot (Scophthalmus maximus)-rearing farm and antagonize Vibrio anguillarum under different growth conditions. Appl Environ Microbiol (2008) 1.24

Horizontal gene transfer and nucleotide compositional anomaly in large DNA viruses. BMC Genomics (2007) 1.23

TEnest: automated chronological annotation and visualization of nested plant transposable elements. Plant Physiol (2007) 1.23

Whole genome molecular phylogeny of large dsDNA viruses using composition vector method. BMC Evol Biol (2007) 1.22

Early evolution of histone mRNA 3' end processing. RNA (2007) 1.20

Phylogenetic distances are encoded in networks of interacting pathways. Bioinformatics (2008) 1.19

methBLAST and methPrimerDB: web-tools for PCR based methylation analysis. BMC Bioinformatics (2006) 1.18

A global public database of disease vector and reservoir distributions. PLoS Negl Trop Dis (2009) 1.18

The (in)dependence of alternative splicing and gene duplication. PLoS Comput Biol (2007) 1.17

Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Nucleic Acids Res (2006) 1.17

Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-function. J Lipid Res (2010) 1.17

Strainer: software for analysis of population variation in community genomic datasets. BMC Bioinformatics (2007) 1.16

Abundance and functional diversity of riboswitches in microbial communities. BMC Genomics (2007) 1.16

The network of sequence flow between protein structures. Proc Natl Acad Sci U S A (2007) 1.15

xGDB: open-source computational infrastructure for the integrated evaluation and analysis of genome features. Genome Biol (2006) 1.14

Diversity and stratification of archaea in a hypersaline microbial mat. Appl Environ Microbiol (2008) 1.14

3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales. J Bacteriol (2009) 1.13

The Innate Immune Database (IIDB). BMC Immunol (2008) 1.11

Conversion and compensatory evolution of the gamma-crystallin genes and identification of a cataractogenic mutation that reverses the sequence of the human CRYGD gene to an ancestral state. Am J Hum Genet (2007) 1.10

Evolution of acetoclastic methanogenesis in Methanosarcina via horizontal gene transfer from cellulolytic Clostridia. J Bacteriol (2007) 1.09

Malonic semialdehyde reductase, succinic semialdehyde reductase, and succinyl-coenzyme A reductase from Metallosphaera sedula: enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in Sulfolobales. J Bacteriol (2009) 1.07

Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites. BMC Bioinformatics (2008) 1.06

Exchanging murine and human immunoglobulin constant chains affects the kinetics and thermodynamics of antigen binding and chimeric antibody autoreactivity. PLoS One (2007) 1.05

Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome. BMC Bioinformatics (2006) 1.04

Homology modeling of major intrinsic proteins in rice, maize and Arabidopsis: comparative analysis of transmembrane helix association and aromatic/arginine selectivity filters. BMC Struct Biol (2007) 1.04

Analysis of Borrelia burgdorferi genotypes in patients with Lyme arthritis: High frequency of ribosomal RNA intergenic spacer type 1 strains in antibiotic-refractory arthritis. Arthritis Rheum (2009) 1.02

Ashbya Genome Database 3.0: a cross-species genome and transcriptome browser for yeast biologists. BMC Genomics (2007) 1.01

Extensive parallelism in protein evolution. Biol Direct (2007) 1.00

siVirus: web-based antiviral siRNA design software for highly divergent viral sequences. Nucleic Acids Res (2006) 0.99

Wheat Estimated Transcript Server (WhETS): a tool to provide best estimate of hexaploid wheat transcript sequence. Nucleic Acids Res (2007) 0.97

Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Res (2007) 0.96

Recent transfer of an iron-regulated gene from the plastid to the nuclear genome in an oceanic diatom adapted to chronic iron limitation. BMC Genomics (2010) 0.94

Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties. BMC Bioinformatics (2007) 0.93

Epithelial-to-mesenchymal transition in early transplant tubulointerstitial damage. J Am Soc Nephrol (2008) 0.93

The ENCODEdb portal: simplified access to ENCODE Consortium data. Genome Res (2007) 0.92

Conserved and species-specific alternative splicing in mammalian genomes. BMC Evol Biol (2007) 0.92

A novel filamentous phage from the deep-sea bacterium Shewanella piezotolerans WP3 is induced at low temperature. J Bacteriol (2007) 0.92

HCV genotyping using statistical classification approach. J Biomed Sci (2009) 0.92

Genomic analysis indicates the presence of an asymmetric bilayer outer membrane in planctomycetes and verrucomicrobia. Front Microbiol (2012) 0.92

Analysis of expressed sequence tags and identification of genes encoding cell-wall-degrading enzymes from the fungivorous nematode Aphelenchus avenae. BMC Genomics (2009) 0.92

Estimating the rate of irreversibility in protein evolution. Genome Biol Evol (2012) 0.91

From benchtop to desktop: important considerations when designing amplicon sequencing workflows. PLoS One (2015) 0.90

BCL::Align-sequence alignment and fold recognition with a custom scoring function online. Gene (2008) 0.90

Molecular epidemiology of contemporary G2P[4] human rotaviruses cocirculating in a single U.S. community: footprints of a globally transitioning genotype. J Virol (2014) 0.90

Distinct profiles of expressed sequence tags during intestinal regeneration in the sea cucumber Holothuria glaberrima. Physiol Genomics (2007) 0.89

Genetic diversity in cultured and wild marine cyanomyoviruses reveals phosphorus stress as a strong selective agent. ISME J (2013) 0.89

Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology. BMC Bioinformatics (2013) 0.89

Biochemical and functional evidence of p53 homology is inconsistent with molecular phylogenetics for distant sequences. J Mol Evol (2008) 0.88

Extensive local gene duplication and functional divergence among paralogs in Atlantic salmon. Genome Biol Evol (2014) 0.88

Combined small RNA and degradome sequencing reveals novel miRNAs and their targets in response to low nitrate availability in maize. Ann Bot (2013) 0.88

ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts. BMC Bioinformatics (2008) 0.87

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DDBJ in collaboration with mass-sequencing teams on annotation. Nucleic Acids Res (2005) 3.14

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The NCBI dbGaP database of genotypes and phenotypes. Nat Genet (2007) 17.93

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New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76

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CDART: protein homology by domain architecture. Genome Res (2002) 12.95

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GenBank: update. Nucleic Acids Res (2004) 12.28

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BioProject and BioSample databases at NCBI: facilitating capture and organization of metadata. Nucleic Acids Res (2011) 6.69

Whole-genome analysis of human influenza A virus reveals multiple persistent lineages and reassortment among recent H3N2 viruses. PLoS Biol (2005) 5.48

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The universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages. Proc Natl Acad Sci U S A (2009) 2.50

Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Am J Epidemiol (2009) 2.15

The genome Assembly Archive: a new public resource. PLoS Biol (2004) 2.09

The genomic standards consortium: bringing standards to life for microbial ecology. ISME J (2011) 1.52

Comparative analysis of orthologous eukaryotic mRNAs: potential hidden functional signals. Nucleic Acids Res (2004) 1.49

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A community experiment with fully open and published peer review. Biol Direct (2006) 1.09

Evolutionary dynamics of N-glycosylation sites of influenza virus hemagglutinin. PLoS Curr (2009) 1.06

Projection of seasonal influenza severity from sequence and serological data. PLoS Curr (2010) 1.03

Sequential seasonal H1N1 influenza virus infections protect ferrets against novel 2009 H1N1 influenza virus. J Virol (2012) 1.02

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