Published in Am J Epidemiol on June 04, 2009
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
The PhenX Toolkit: get the most from your measures. Am J Epidemiol (2011) 4.19
Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence. Lancet Oncol (2011) 2.85
Phenopedia and Genopedia: disease-centered and gene-centered views of the evolving knowledge of human genetic associations. Bioinformatics (2009) 2.59
Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer. Trends Genet (2010) 1.83
Testicular cancer survivorship: research strategies and recommendations. J Natl Cancer Inst (2010) 1.76
Cancer GAMAdb: database of cancer genetic associations from meta-analyses and genome-wide association studies. Eur J Hum Genet (2011) 1.69
Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases. PLoS Genet (2012) 1.55
Evolutionary evidence of the effect of rare variants on disease etiology. Clin Genet (2010) 1.54
Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence. Gut (2013) 1.51
The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. Hum Mol Genet (2009) 1.35
Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop. Genet Epidemiol (2011) 1.33
The effect of algorithms on copy number variant detection. PLoS One (2010) 1.23
Genetic variation at a single locus and age of onset for Alzheimer's disease. Alzheimers Dement (2010) 1.19
Knowledge integration in cancer: current landscape and future prospects. Cancer Epidemiol Biomarkers Prev (2012) 1.19
Genetics of Alzheimer disease in the pre- and post-GWAS era. Alzheimers Res Ther (2010) 1.18
Cancer evolution and individual susceptibility. Integr Biol (Camb) (2011) 1.15
Neurocarta: aggregating and sharing disease-gene relations for the neurosciences. BMC Genomics (2013) 1.06
Biological invasions: a field synopsis, systematic review, and database of the literature. Ecol Evol (2012) 1.04
Effect of population structure corrections on the results of association mapping tests in complex maize diversity panels. Theor Appl Genet (2011) 1.02
Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis Rheumatol (2014) 1.00
A review of genetic association studies of obstructive sleep apnea: field synopsis and meta-analysis. Sleep (2011) 0.97
Using PhenX measures to identify opportunities for cross-study analysis. Hum Mutat (2012) 0.96
Distinguishing true from false positives in genomic studies: p values. Eur J Epidemiol (2013) 0.94
Research guidelines in the era of large-scale collaborations: an analysis of Genome-wide Association Study Consortia. Am J Epidemiol (2012) 0.91
The geometric increase in meta-analyses from China in the genomic era. PLoS One (2013) 0.91
Eating disorders: the current status of molecular genetic research. Eur Child Adolesc Psychiatry (2009) 0.88
Child and adolescent psychiatric genetics. Eur Child Adolesc Psychiatry (2010) 0.86
An Integrative Genomics Approach for Associating GWAS Information with Triple-Negative Breast Cancer. Cancer Inform (2013) 0.86
Assessment of cumulative evidence for the association between glutathione S-transferase polymorphisms and lung cancer: application of the Venice interim guidelines. Pharmacogenet Genomics (2010) 0.80
Stroke genome-wide association studies: the large numbers imperative. Stroke (2010) 0.80
Association of a novel functional promoter variant (rs2075533 C>T) in the apoptosis gene TNFSF8 with risk of lung cancer--a finding from Texas lung cancer genome-wide association study. Carcinogenesis (2011) 0.79
Genetic epidemiology with a capital E: where will we be in another 10 years? Genet Epidemiol (2012) 0.78
Integrative genomic analysis for the discovery of biomarkers in prostate cancer. Biomark Insights (2014) 0.78
A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. Database (Oxford) (2014) 0.77
Familial colorectal cancer: a review. World J Gastroenterol (2014) 0.77
Comprehensive assessment and network analysis of the emerging genetic susceptibility landscape of prostate cancer. Cancer Inform (2013) 0.77
Assessment of systematic effects of methodological characteristics on candidate genetic associations. Hum Genet (2012) 0.77
Updated field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma: the MelGene database. J Invest Dermatol (2014) 0.76
Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies. Pigment Cell Melanoma Res (2013) 0.76
Elevated DISC1 transcript levels in PBMCs during acute psychosis in patients with schizophrenia. Transl Biomed (2011) 0.76
Meta-analysis for genome-wide association studies using case-control design: application and practice. Epidemiol Health (2016) 0.75
Novel Integrative Genomics Approach for Associating GWAS Information with Intrinsic Subtypes of Breast Cancer. Cancer Inform (2013) 0.75
An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes. Biomark Insights (2017) 0.75
Why most published research findings are false. PLoS Med (2005) 41.68
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science (2007) 32.97
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science (2008) 20.68
Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays. PLoS Genet (2008) 20.38
Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst (2004) 19.00
A HapMap harvest of insights into the genetics of common disease. J Clin Invest (2008) 18.31
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Replicating genotype-phenotype associations. Nature (2007) 16.11
Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet (2008) 13.95
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet (2007) 12.13
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol (2008) 11.28
Why most discovered true associations are inflated. Epidemiology (2008) 11.22
Letting the genome out of the bottle--will we get our wish? N Engl J Med (2008) 9.10
Overcoming the winner's curse: estimating penetrance parameters from case-control data. Am J Hum Genet (2007) 6.99
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71
Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J (2001) 5.94
Heterogeneity in meta-analyses of genome-wide association investigations. PLoS One (2007) 5.77
Uncertainty in heterogeneity estimates in meta-analyses. BMJ (2007) 5.69
A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. Stat Med (2006) 5.43
A navigator for human genome epidemiology. Nat Genet (2008) 5.07
NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. Lancet (2005) 5.01
Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol (2007) 4.96
Bayes factors for genome-wide association studies: comparison with P-values. Genet Epidemiol (2009) 4.33
A Bayesian measure of the probability of false discovery in genetic epidemiology studies. Am J Hum Genet (2007) 4.21
An exploratory test for an excess of significant findings. Clin Trials (2007) 3.83
Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol (2008) 3.26
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
Non-replication and inconsistency in the genome-wide association setting. Hum Hered (2007) 2.99
GeneTests: an online genetic information resource for health care providers. J Med Libr Assoc (2006) 2.36
The genomics gold rush. JAMA (2007) 2.35
Tracking the epidemiology of human genes in the literature: the HuGE Published Literature database. Am J Epidemiol (2006) 2.34
A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. J Natl Cancer Inst (2008) 2.29
A polygenic basis for late-onset disease. Trends Genet (2003) 2.05
Recommendations of the 2006 Human Variome Project meeting. Nat Genet (2007) 1.90
Required sample size and nonreplicability thresholds for heterogeneous genetic associations. Proc Natl Acad Sci U S A (2008) 1.84
Genome-wide association studies: progress and potential for drug discovery and development. Nat Rev Drug Discov (2008) 1.45
A network of investigator networks in human genome epidemiology. Am J Epidemiol (2005) 1.43
Ascertainment adjustment: where does it take us? Am J Hum Genet (2000) 1.30
Positively disruptive. Nat Genet (2008) 1.16
The Human Genome Epidemiology Network. Am J Epidemiol (1998) 1.15
Commentary: Reflections on G. M. Lower and colleagues' 1979 study associating slow acetylator phenotype with urinary bladder cancer: meta-analysis, historical refinements of the hypothesis, and lessons learned. Int J Epidemiol (2007) 1.13
Calibration of credibility of agnostic genome-wide associations. Am J Med Genet B Neuropsychiatr Genet (2008) 1.12
STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement. Ann Intern Med (2009) 1.11
Risky business. Nat Genet (2007) 0.88
Embracing risk. Nat Genet (2006) 0.79
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet (2010) 26.48
Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000. Lancet (2012) 25.96
GenBank. Nucleic Acids Res (2007) 25.54
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2005) 22.98
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2007) 22.53
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ (2009) 22.18
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med (2009) 21.74
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2008) 21.36
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
GenBank. Nucleic Acids Res (2005) 19.25
Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst (2004) 19.00
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2006) 18.85
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2006) 18.84
The NCBI dbGaP database of genotypes and phenotypes. Nat Genet (2007) 17.93
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
GenBank. Nucleic Acids Res (2002) 17.24
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
GenBank. Nucleic Acids Res (2007) 16.92
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Replicating genotype-phenotype associations. Nature (2007) 16.11
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes. Genome Res (2009) 14.90
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet (2010) 13.86
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Power failure: why small sample size undermines the reliability of neuroscience. Nat Rev Neurosci (2013) 13.37
Systematic review of the empirical evidence of study publication bias and outcome reporting bias. PLoS One (2008) 13.32
GenBank. Nucleic Acids Res (2008) 13.29
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. Ann Intern Med (2014) 12.79
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2009) 12.51
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
GenBank: update. Nucleic Acids Res (2004) 12.28
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
GenBank. Nucleic Acids Res (2006) 12.21
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med (2009) 12.16
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol (2009) 11.80
GenBank. Nucleic Acids Res (2009) 11.11
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2010) 10.97
GenBank. Nucleic Acids Res (2012) 10.89
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science (2009) 10.78
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet (2009) 10.34
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet (2007) 9.88
GenBank. Nucleic Acids Res (2003) 9.60
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention? Genet Med (2007) 9.48
Global burden of childhood pneumonia and diarrhoea. Lancet (2013) 9.28
Epidemiology and etiology of childhood pneumonia. Bull World Health Organ (2008) 9.17
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat Genet (2010) 9.07
How should meta-regression analyses be undertaken and interpreted? Stat Med (2002) 8.96
Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA (2010) 8.93
GenBank. Nucleic Acids Res (2011) 8.85
GenBank. Nucleic Acids Res (2010) 8.63
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2011) 8.62
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell (2005) 8.40
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
The case of the misleading funnel plot. BMJ (2006) 8.26
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ (2014) 7.21
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med (2005) 7.09
Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography. Int J Epidemiol (2007) 7.00
Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure. Stat Med (2005) 6.99
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet (2009) 6.91
Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med (2011) 6.89
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ (2011) 6.80
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71