Published in Proc Natl Acad Sci U S A on January 01, 1975
Effect of the anesthetics benzyl alcohol and chloroform on bilayers made from monolayers. Biophys J (1979) 1.78
Effect of anesthetics and pressure on the thermotropic behavior of multilamellar dipalmitoylphosphatidylcholine liposomes. Proc Natl Acad Sci U S A (1978) 1.27
Liquid general anesthetics lower critical temperatures in plasma membrane vesicles. Biophys J (2013) 1.08
The thermodynamics of general anesthesia. Biophys J (2007) 1.06
The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics. Biophys J (2009) 1.02
New insights into the molecular mechanisms of general anaesthetics. Br J Pharmacol (2010) 1.02
Early ultrastructural changes in skeletal muscle exposed to the local anaesthetic bupivacaine (Marcaine). Br J Exp Pathol (1980) 1.00
Xenon and other volatile anesthetics change domain structure in model lipid raft membranes. J Phys Chem B (2013) 0.86
Halothane changes the domain structure of a binary lipid membrane. Langmuir (2012) 0.86
Effects of the anesthetic dibucaine on the kinetics of the gel-liquid crystalline transition of dipalmitoylphosphatidylcholine multilamellar vesicles. Biophys J (1992) 0.85
A unitary theory of anesthesia based on lateral phase separations in nerve membranes [proceedings]. Biophys J (1977) 0.77
The thermodynamics of general and local anesthesia. Biophys J (2014) 0.77
The thermodynamics of simple biomembrane mimetic systems. J Pharm Bioallied Sci (2011) 0.75
Direct comparison of elastic incoherent neutron scattering experiments with molecular dynamics simulations of DMPC phase transitions. Eur Phys J E Soft Matter (2016) 0.75
Lateral phase separation in phospholipid membranes. Biochemistry (1973) 6.56
Lateral phase separations in membrane lipids and the mechanism of sugar transport in Escherichia coli. Proc Natl Acad Sci U S A (1973) 3.70
Biomembrane phase transitions. Studies of lipid-water systems using differential scanning calorimetry. J Biol Chem (1974) 3.08
Biogenesis of microbial transport systems: evidnce for coupled incorporation of newly synthesized lipids and proteins into membrane. J Mol Biol (1971) 2.16
Pressure reversal of anaesthesia. Nature (1971) 2.10
Temperature- and light-dependent structural changes in rhodopsin-lipid membranes. Exp Eye Res (1973) 1.89
Hydrostatic pressure reversal of narcosis in tadpoles. Science (1950) 1.80
Lateral phase separation of lipids in plasma membranes: effect of temperature on the mobility of membrane antigens. Science (1974) 1.55
Phase transitions and control of cellular metabolism at low temperatures. Cryobiology (1972) 1.45
Phase transitions and bilayer structure of Mycoplasma laidlawii B. FEBS Lett (1971) 1.14
Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled phospholipid vesicles. Biochim Biophys Acta (1973) 1.08
The fraction of the lipid in a biological membrane that is in a fluid state: a spin label assay. Biochem Biophys Res Commun (1972) 1.04
Perturbations of the dynamics of lipid alkyl chains in membrane systems: effect on the activity of membrane-bound enzymes. Biochim Biophys Acta (1974) 1.02
Pressure reversal of anesthesia: the extent of small-molecule exclusion from spin-labeled phospholipid model membranes. Anesthesiology (1973) 0.90
The effect of pressure on the phase diagram of mixed dipalmitoyl-dimyristoylphosphatidylcholine bilayers. Biochim Biophys Acta (1974) 0.85
Surface properties of synthetic phospholipids. II. Thermal phase transitions in monolayers. Biochim Biophys Acta (1973) 0.82
Anesthesia, pregnancy, and miscarriage: a study of operating room nurses and anesthetists. Anesthesiology (1971) 2.85
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2. Biochem J (1996) 2.55
Methoxyflurane metabolism and renal dysfunction: clinical correlation in man. Anesthesiology (1971) 2.39
Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proc Natl Acad Sci U S A (2000) 2.24
Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2. J Clin Invest (1997) 2.04
Anesthetics and ion channels: molecular models and sites of action. Annu Rev Pharmacol Toxicol (2001) 2.01
Evidence for a common binding cavity for three general anesthetics within the GABAA receptor. J Neurosci (2001) 2.00
Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2. Proc Natl Acad Sci U S A (1997) 1.99
Mechanisms of desensitization and resensitization of proteinase-activated receptor-2. J Biol Chem (1996) 1.99
Neutrophil rolling altered by inhibition of L-selectin shedding in vitro. Nature (1996) 1.90
Occupational disease in dentistry and chronic exposure to trace anesthetic gases. J Am Dent Assoc (1980) 1.90
Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB. Curr Biol (1999) 1.85
Hypothesis: inhaled anesthetics produce immobility and amnesia by different mechanisms at different sites. Anesth Analg (1997) 1.80
Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proc Natl Acad Sci U S A (1998) 1.76
Effects of low concentrations of ethanol on the fluidity of spin-labeled erythrocyte and brain membranes. Mol Pharmacol (1977) 1.74
Chronic exposure to anesthetic gases in the operating room. Anesthesiology (1971) 1.73
A survey of anesthetic health hazards among dentists. J Am Dent Assoc (1975) 1.70
Dominant effector genetics in mammalian cells. Nat Genet (2001) 1.68
Detection of programmed cell death using fluorescence energy transfer. Nucleic Acids Res (1998) 1.65
Specific stimulation of human T lymphocytes by substance P. J Immunol (1983) 1.65
Characterization of antisera specific to NK1, NK2, and NK3 neurokinin receptors and their utilization to localize receptors in the rat gastrointestinal tract. J Neurosci (1996) 1.58
Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Mol Biol Cell (1995) 1.52
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton. J Biol Chem (1999) 1.50
Structure and expression of a rat agrin. Neuron (1991) 1.49
Drug tolerance in biomembranes: a spin label study of the effects of ethanol. Science (1977) 1.46
Binding of viridans group streptococci to human platelets: a quantitative analysis. Infect Immun (1990) 1.41
p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues. Oncogene (2001) 1.41
A unitary theory of anesthesia based on lateral phase separations in nerve membranes. Anesthesiology (1977) 1.40
Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J Neurosci (1994) 1.40
Occupational hazards for operating room-based physicians. Analysis of data from the United States and the United Kingdom. JAMA (1977) 1.38
Recurrent stroke caused by spondylotic compression of the vertebral artery. Ann Neurol (1993) 1.38
Neuroimmunology. Adv Immunol (1986) 1.37
Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay. Cytometry (1999) 1.32
Substance P recognition by a subset of human T lymphocytes. J Clin Invest (1984) 1.31
The control of microvascular permeability and blood pressure by neutral endopeptidase. Nat Med (1997) 1.31
Substance P selectively activates TNF-alpha gene expression in murine mast cells. J Immunol (1993) 1.29
Minimum alveolar concentrations of noble gases, nitrogen, and sulfur hexafluoride in rats: helium and neon as nonimmobilizers (nonanesthetics) Anesth Analg (1998) 1.28
The metabolism and elimination of d-tubocurarine-H3. Anesthesiology (1967) 1.22
Distribution of substance P receptors on murine spleen and Peyer's patch T and B cells. J Immunol (1987) 1.22
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells. Biochem J (1994) 1.22
The rates of interaction of local anesthetics with sodium channels in nerve. J Pharmacol Exp Ther (1978) 1.20
Membrane-disordering action of ethanol: variation with membrane cholesterol content and depth of the spin label probe. Mol Pharmacol (1981) 1.18
Prophylactic control of post-operative nausea and vomiting using ondansetron and ramosetron after cardiac surgery. Acta Anaesthesiol Scand (2010) 1.16
Letter: Oxidized cytochrome P-450. Magnetic circular dichroism evidence for thiolate ligation in the substrate-bound form. Implications for the catalytic mechanism. J Am Chem Soc (1976) 1.15
Endocytosis and recycling of neurokinin 1 receptors in enteric neurons. Neuroscience (1996) 1.15
Application of low-temperature autoradiography to studies of the uptake and metabolism of volatile anesthetics in the mouse. 3. Halothane. Anesthesiology (1969) 1.15
Pressure-induced elevation of phase transition temperature in dipalmitoylphosphatidylcholine bilayers. An electron spin resonance measurement of the enthalpy of phase transition. Biochim Biophys Acta (1974) 1.14
Surgery during pregnancy and fetal outcome. Am J Obstet Gynecol (1980) 1.14
Stereospecific receptors for substance P on cultured human IM-9 lymphoblasts. J Immunol (1984) 1.12
Metabolism of the volatile anesthetics. Anesthesiology (1971) 1.11
Substance P and bradykinin stimulate plasma extravasation in the mouse gastrointestinal tract and pancreas. Am J Physiol (1997) 1.11
Effects of pressure and anesthetics on conduction and synaptic transmission. J Pharmacol Exp Ther (1975) 1.10
Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor. J Biol Chem (1997) 1.10
Interactions between neutral endopeptidase (EC 3.4.24.11) and the substance P (NK1) receptor expressed in mammalian cells. Biochem J (1994) 1.10
Pressure reversal of inhalation anesthetic-induced disorder in spin-labeled phospholipid vesicles. Biochim Biophys Acta (1973) 1.08
Inhibition by somatostatin of the proliferation of T-lymphocytes and Molt-4 lymphoblasts. Cell Immunol (1984) 1.08
Human T-lymphocyte subset specificity of the regulatory effects of leukotriene B4. Proc Natl Acad Sci U S A (1984) 1.07
The effect of two inhalation anesthetics on the order of spin-labeled phospholipid vesicles. Biochim Biophys Acta (1973) 1.07
Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol. Br J Pharmacol (2000) 1.07
Application of low-temperature autoradiography to studies of the uptake and metabolism of volatile anesthetics in the mouse. I. Chloroform. Anesthesiology (1969) 1.07
Immunomodulation by tachykinin neuropeptides. Ann N Y Acad Sci (1990) 1.06
Halothane and the liver: a review of the epidemiologic, immunologic and metabolic aspects of the relationship. Can J Surg (1972) 1.06
Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid. J Clin Immunol (1986) 1.05
Neuropeptide regulation of the expression of immediate hypersensitivity. J Immunol (1985) 1.05
Molecular cloning, chromosomal localization, and expression of murine dipeptidyl peptidase I. J Biol Chem (1997) 1.05
Localization of molecular halothane in phospholipid bilayer model nerve membranes. Anesthesiology (1976) 1.05
Use of whole-body autoradiography for determination of uptake and distribution of labeled muscle relaxants in the rat. Anesthesiology (1968) 1.04
Infection of a brain abscess of Mycoplasma hominis. J Clin Microbiol (1981) 1.04
Specific suppression of human T lymphocyte function by leukotriene B4. J Immunol (1983) 1.04
Structural elements involved in activation of the gamma-aminobutyric acid type A (GABAA) receptor. Biochem Soc Trans (2004) 1.03
Magnetic circular dichroism studies. XXV. A preliminary investigation of microsomal cytochromes. Proc Natl Acad Sci U S A (1974) 1.01
Stable, stoichiometric delivery of diverse protein functions. J Biochem Biophys Methods (2004) 1.01
Anesthetics: molecular correlates of voltage- and frequency-dependent sodium channel block in nerve. J Pharmacol Exp Ther (1979) 1.01
Rab37 is a novel mast cell specific GTPase localized to secretory granules. FEBS Lett (2000) 1.01
Retroviral delivery of peptide modulators of cellular functions. Mol Ther (2000) 1.01
Effect of eicosapentaenoic acid in asthma. Clin Allergy (1988) 1.00
Substance P and immunoregulation. Fed Proc (1987) 1.00
Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues. ACS Chem Neurosci (2010) 1.00
Heat shock activates c-Src tyrosine kinases and phosphatidylinositol 3-kinase in NIH3T3 fibroblasts. J Biol Chem (1997) 1.00
Interaction of ethanol with biological membranes. Fed Proc (1981) 1.00
Increased cholesterol content of erythrocyte and brain membranes in ethanol-tolerant mice. Biochim Biophys Acta (1978) 0.99
Defective polymorphonuclear leukocyte chemotaxis in homosexual men with persistent lymph node syndrome. J Infect Dis (1984) 0.98
Urinary metabolites of halothane in man. Anesthesiology (1975) 0.97
Multiple signaling pathways of histamine H2 receptors. Identification of an H2 receptor-dependent Ca2+ mobilization pathway in human HL-60 promyelocytic leukemia cells. J Biol Chem (1989) 0.97
Generation of a unique fibroblast-activating factor by human monocytes. Immunology (1984) 0.96
Sperm studies in anesthesiologists. Anesthesiology (1981) 0.96
Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine. Proc Natl Acad Sci U S A (1982) 0.96
Intracellular protein scaffold-mediated display of random peptide libraries for phenotypic screens in mammalian cells. Chem Biol (2001) 0.96
Exposure to nitrous oxide and neurologic disease among dental professionals. Anesth Analg (1981) 0.95
Magnolol attenuates peroxidative damage and improves survival of rats with sepsis. Shock (2000) 0.94
Direct observation of endocytosis of gastrin releasing peptide and its receptor. J Biol Chem (1995) 0.94
Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization. Biochemistry (1996) 0.94