Published in J Mol Biol on December 22, 2005
Molecular details of cAMP generation in mammalian cells: a tale of two systems. J Mol Biol (2006) 2.05
Cyclic AMP in mycobacteria: characterization and functional role of the Rv1647 ortholog in Mycobacterium smegmatis. J Bacteriol (2008) 0.99
Expression of a subset of heat stress induced genes of mycobacterium tuberculosis is regulated by 3',5'-cyclic AMP. PLoS One (2014) 0.80
The Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage. Microbiol Spectr (2016) 0.75
New structural forms of a mycobacterial adenylyl cyclase Rv1625c. IUCrJ (2014) 0.75
Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria. Biol Direct (2016) 0.75
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin. Proc Natl Acad Sci U S A (2009) 4.88
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. Science (2011) 3.00
Familial diarrhea syndrome caused by an activating GUCY2C mutation. N Engl J Med (2012) 2.04
T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface. Immunity (2007) 1.92
IFN-inducible GTPases in host cell defense. Cell Host Microbe (2012) 1.53
Functional classification of immune regulatory proteins. Structure (2013) 1.49
Structural genomics of protein phosphatases. J Struct Funct Genomics (2007) 1.40
Site-directed mutagenesis using a single mutagenic oligonucleotide and DpnI digestion of template DNA. Anal Biochem (2003) 1.36
Class III nucleotide cyclases in bacteria and archaebacteria: lineage-specific expansion of adenylyl cyclases and a dearth of guanylyl cyclases. FEBS Lett (2004) 1.34
New messages from old messengers: cAMP and mycobacteria. Trends Microbiol (2006) 1.33
Structural effects of radiation damage and its potential for phasing. Acta Crystallogr D Biol Crystallogr (2004) 1.28
NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family. Immunity (2006) 1.27
The Rv0805 gene from Mycobacterium tuberculosis encodes a 3',5'-cyclic nucleotide phosphodiesterase: biochemical and mutational analysis. Biochemistry (2005) 1.26
IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol (2012) 1.24
Structural and biochemical analysis of the Rv0805 cyclic nucleotide phosphodiesterase from Mycobacterium tuberculosis. J Mol Biol (2006) 1.20
cAMP-regulated protein lysine acetylases in mycobacteria. J Biol Chem (2010) 1.18
Mycobacterial adenylyl cyclases: biochemical diversity and structural plasticity. FEBS Lett (2006) 1.12
Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function. Proc Natl Acad Sci U S A (2007) 1.11
Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA. Biochemistry (2008) 1.10
Sequence, structure, function, immunity: structural genomics of costimulation. Immunol Rev (2009) 1.08
Cyclic AMP-dependent protein lysine acylation in mycobacteria regulates fatty acid and propionate metabolism. J Biol Chem (2013) 1.08
A mycobacterial cyclic AMP phosphodiesterase that moonlights as a modifier of cell wall permeability. J Biol Chem (2009) 1.06
Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily. Proc Natl Acad Sci U S A (2008) 1.06
Structural basis for the variation in triclosan affinity to enoyl reductases. J Mol Biol (2004) 1.05
Analysis of proteins with the 'hot dog' fold: prediction of function and identification of catalytic residues of hypothetical proteins. BMC Struct Biol (2009) 1.03
Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proc Natl Acad Sci U S A (2010) 1.03
Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G protein in human proximal tubule cells. J Biol Chem (2002) 1.02
A survey of nucleotide cyclases in actinobacteria: unique domain organization and expansion of the class III cyclase family in Mycobacterium tuberculosis. Comp Funct Genomics (2004) 1.02
Cyclic AMP in mycobacteria: characterization and functional role of the Rv1647 ortholog in Mycobacterium smegmatis. J Bacteriol (2008) 0.99
Crystal structure of Escherichia coli Rnk, a new RNA polymerase-interacting protein. J Mol Biol (2008) 0.99
Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips. FEBS Lett (2006) 0.98
Expression of the receptor guanylyl cyclase C and its ligands in reproductive tissues of the rat: a potential role for a novel signaling pathway in the epididymis. Biol Reprod (2002) 0.97
L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase. J Am Chem Soc (2007) 0.95
The evolution of guanylyl cyclases as multidomain proteins: conserved features of kinase-cyclase domain fusions. J Mol Evol (2009) 0.94
Characterization of phylogenetically distant members of the adenylate cyclase family from mycobacteria: Rv1647 from Mycobacterium tuberculosis and its orthologue ML1399 from M. leprae. Biochem J (2005) 0.94
Receptor guanylyl cyclase C (GC-C): regulation and signal transduction. Mol Cell Biochem (2009) 0.93
Glycosylation of the receptor guanylate cyclase C: role in ligand binding and catalytic activity. Biochem J (2004) 0.92
Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin. J Biol Chem (2006) 0.91
Structure and T cell inhibition properties of B7 family member, B7-H3. Structure (2013) 0.90
The linker region in receptor guanylyl cyclases is a key regulatory module: mutational analysis of guanylyl cyclase C. J Biol Chem (2009) 0.90
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion. Proc Natl Acad Sci U S A (2012) 0.90
Characterization of an evolutionarily conserved metallophosphoesterase that is expressed in the fetal brain and associated with the WAGR syndrome. J Biol Chem (2008) 0.89
Tyrphostins are inhibitors of guanylyl and adenylyl cyclases. Biochemistry (2004) 0.89
Mutational analysis of the Mycobacterium tuberculosis Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerization. FEBS Lett (2003) 0.89
The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis. FEBS Lett (2012) 0.89
Modeling and mutational analysis of the GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase, PDE5. FEBS Lett (2003) 0.89
Signalling mechanisms in Mycobacteria. Tuberculosis (Edinb) (2011) 0.89
Novel pentameric structure of the diarrhea-inducing region of the rotavirus enterotoxigenic protein NSP4. J Virol (2011) 0.88
Cyclic AMP-induced conformational changes in mycobacterial protein acetyltransferases. J Biol Chem (2012) 0.88
Exploring the interaction energies for the binding of hydroxydiphenyl ethers to enoyl-acyl carrier protein reductases. J Biomol Struct Dyn (2003) 0.87
De novo design and characterization of a helical hairpin eicosapeptide; emergence of an anion receptor in the linker region. Structure (2004) 0.86
The GAF domain of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) is a sensor and a sink for cGMP. Biochemistry (2008) 0.85
Cross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis. Mol Cell Biol (2009) 0.85
Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21. J Biol Chem (2013) 0.84
Advantage of the ether linkage between the positive charge and the cholesteryl skeleton in cholesterol-based amphiphiles as vectors for gene delivery. Bioconjug Chem (2002) 0.83
Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells. Proc Natl Acad Sci U S A (2011) 0.83
The kinase homology domain of receptor guanylyl cyclase C: ATP binding and identification of an adenine nucleotide sensitive site. Biochemistry (2006) 0.83
Distinct allostery induced in the cyclic GMP-binding, cyclic GMP-specific phosphodiesterase (PDE5) by cyclic GMP, sildenafil, and metal ions. J Biol Chem (2010) 0.83
Generation of blood group specificity: new insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean agglutinin. Proteins (2007) 0.83
The flexible C terminus of the rotavirus non-structural protein NSP4 is an important determinant of its biological properties. J Gen Virol (2008) 0.82
Evolution of a protein-folding machine: genomic and evolutionary analyses reveal three lineages of the archaeal hsp70(dnaK) gene. J Mol Evol (2006) 0.82
Effect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from Plasmodium falciparum. IUBMB Life (2011) 0.81
Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response. Tuberculosis (Edinb) (2013) 0.81
Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome. J Mol Biol (2011) 0.81
Purification, crystallization and preliminary X-ray diffraction analysis of the catalytic domain of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr (2004) 0.81
The ascent of nucleotide cyclases: conservation and evolution of a theme. J Biosci (2002) 0.80
Structural basis for the specificity of basic winged bean lectin for the Tn-antigen: a crystallographic, thermodynamic and modelling study. FEBS Lett (2005) 0.80
Histone deacetylases regulate multicellular development in the social amoeba Dictyostelium discoideum. J Mol Biol (2009) 0.80
The cGMP-binding, cGMP-specific phosphodiesterase (PDE5): intestinal cell expression, regulation and role in fluid secretion. Cell Signal (2004) 0.80
Biopanning of endotoxin-specific phage displayed peptides. Biochem Biophys Res Commun (2003) 0.79
Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C. Eur J Biochem (2003) 0.79
Structural basis for the functional and inhibitory mechanisms of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Plasmodium falciparum. J Struct Biol (2011) 0.78
Site-specific N-linked glycosylation of receptor guanylyl cyclase C regulates ligand binding, ligand-mediated activation and interaction with vesicular integral membrane protein 36, VIP36. J Biol Chem (2012) 0.78
1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells. Acta Crystallogr D Biol Crystallogr (2009) 0.78
Affinity of a galactose-specific legume lectin from Dolichos lablab to adenine revealed by X-ray cystallography. IUBMB Life (2013) 0.77
Structural biology of Mycobacterium tuberculosis proteins: the Indian efforts. Tuberculosis (Edinb) (2011) 0.77
A fluorescent nucleic acid nanodevice quantitatively images elevated cyclic adenosine monophosphate in membrane-bound compartments. Small (2014) 0.77
The adenylyl cyclase Rv2212 modifies the proteome and infectivity of Mycobacterium bovis BCG. Folia Microbiol (Praha) (2014) 0.77
Cyclic nucleotide signaling in intestinal epithelia: getting to the gut of the matter. Wiley Interdiscip Rev Syst Biol Med (2013) 0.77
Crystallization and preliminary crystallographic analysis of beta-hydroxyacyl ACP dehydratase (FabZ) from Plasmodium falciparum. Acta Crystallogr D Biol Crystallogr (2003) 0.77
Severe diffraction anisotropy, rotational pseudosymmetry and twinning complicate the refinement of a pentameric coiled-coil structure of NSP4 of rotavirus. Acta Crystallogr D Biol Crystallogr (2012) 0.77
Packing and loop-structure variations in non-isomorphous crystals of FabZ from Plasmodium falciparum. Acta Crystallogr D Biol Crystallogr (2007) 0.77
Crystal structure of a putative aspartic proteinase domain of the Mycobacterium tuberculosis cell surface antigen PE_PGRS16. FEBS Open Bio (2013) 0.77
Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. Int Immunol (2010) 0.77
Insights into the substrate specificity of a thioesterase Rv0098 of mycobacterium tuberculosis through X-ray crystallographic and molecular dynamics studies. J Biomol Struct Dyn (2012) 0.76
Modification of the sugar specificity of a plant lectin: structural studies on a point mutant of Erythrina corallodendron lectin. Acta Crystallogr D Biol Crystallogr (2011) 0.76
Paralogous cAMP receptor proteins in Mycobacterium smegmatis show biochemical and functional divergence. Biochemistry (2014) 0.76
Characterization of rice small heat shock proteins targeted to different cellular organelles. Cell Stress Chaperones (2015) 0.75
Observation of glycine zipper and unanticipated occurrence of ambidextrous helices in the crystal structure of a chiral undecapeptide. BMC Struct Biol (2007) 0.75
Effect of dimethyl sulphoxide on the crystal structure of porcine pepsin. Biochem Biophys Res Commun (2005) 0.75
Structural basis for the carbohydrate-specificity of basic winged-bean lectin and its differential affinity for Gal and GalNAc. Acta Crystallogr D Biol Crystallogr (2006) 0.75
Conformational stability and thermodynamic characterization of homotetrameric Plasmodium falciparum beta-ketoacyl-ACP reductase. IUBMB Life (2007) 0.75