Published in Cell Host Microbe on October 18, 2012
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection. Nature (2013) 2.79
The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice. Cell Host Microbe (2014) 1.85
Cellular self-defense: how cell-autonomous immunity protects against pathogens. Science (2013) 1.39
The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy. Immunity (2014) 1.34
Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii. PLoS Pathog (2013) 1.34
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida. Nat Immunol (2015) 1.23
Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins. Proc Natl Acad Sci U S A (2015) 1.07
Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor. J Virol (2014) 0.99
In vivo physiological and transcriptional profiling reveals host responses to Clostridium difficile toxin A and toxin B. Infect Immun (2013) 0.98
The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance. PLoS One (2014) 0.93
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium. Cell Host Microbe (2015) 0.92
Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity. Front Immunol (2014) 0.91
A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP. Cell Host Microbe (2016) 0.87
The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation. J Exp Med (2016) 0.87
Maintenance of vacuole integrity by bacterial pathogens. Curr Opin Microbiol (2013) 0.87
A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2. J Virol (2015) 0.87
Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analyses. Retrovirology (2015) 0.86
The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases. J Biol Chem (2014) 0.85
Interferon-induced guanylate-binding proteins in inflammasome activation and host defense. Nat Immunol (2016) 0.84
Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins. Nat Commun (2016) 0.83
Deletion of nuoG from the Vaccine Candidate Mycobacterium bovis BCG ΔureC::hly Improves Protection against Tuberculosis. MBio (2016) 0.82
Cell-autonomous effector mechanisms against mycobacterium tuberculosis. Cold Spring Harb Perspect Med (2014) 0.82
Palmitoylation of the immunity related GTPase, Irgm1: impact on membrane localization and ability to promote mitochondrial fission. PLoS One (2014) 0.81
Mycobacterium leprae upregulates IRGM expression in monocytes and monocyte-derived macrophages. Inflammation (2014) 0.79
S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog (2016) 0.79
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. Nat Commun (2016) 0.79
A de novo Assembly of the Common Frog (Rana temporaria) Transcriptome and Comparison of Transcription Following Exposure to Ranavirus and Batrachochytrium dendrobatidis. PLoS One (2015) 0.78
Age-dependent differences in systemic and cell-autonomous immunity to L. monocytogenes. Clin Dev Immunol (2013) 0.78
Predominant role of interferon-γ in the host protective effect of CD8(+) T cells against Neospora caninum infection. Sci Rep (2015) 0.78
Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.78
IFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver. Exp Parasitol (2015) 0.77
Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression. Cell Host Microbe (2016) 0.77
Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination. MBio (2015) 0.77
Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells. Microbiol Spectr (2016) 0.76
RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii. Proc Natl Acad Sci U S A (2015) 0.76
Autophagy gene polymorphism is associated with susceptibility to leprosy by affecting inflammatory cytokines. Inflammation (2014) 0.76
Toxoplasma Effectors Targeting Host Signaling and Transcription. Clin Microbiol Rev (2017) 0.75
Facilitation of Endosomal Recycling by an IRG Protein Homolog Maintains Apical Tubule Structure in Caenorhabditis elegans. Genetics (2016) 0.75
Immune to defeat. Elife (2013) 0.75
IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria. Infect Immun (2015) 0.75
Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design. J Immunol (2017) 0.75
Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. Proc Natl Acad Sci U S A (2017) 0.75
Mycobacterium tuberculosis replicates within necrotic human macrophages. J Cell Biol (2017) 0.75
Guanylate binding protein 5: Impairing virion infectivity by targeting retroviral envelope glycoproteins. Small GTPases (2016) 0.75
Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection. Sci Rep (2017) 0.75
Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages. J Biol Chem (2017) 0.75
Various plus unique: Viral protein U as a plurifunctional protein for HIV-1 replication. Exp Biol Med (Maywood) (2017) 0.75
Guanylate-binding protein 1 inhibits nuclear delivery of Kaposi's sarcoma-associated herpesvirus virions by disrupting formation of actin filament. J Virol (2017) 0.75
Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity. J Cell Mol Med (2017) 0.75
GBPs Inhibit Motility of Shigella flexneri but Are Targeted for Degradation by the Bacterial Ubiquitin Ligase IpaH9.8. Cell Host Microbe (2017) 0.75
Host-Toxoplasma gondii Coadaptation Leads to Fine Tuning of the Immune Response. Front Immunol (2017) 0.75
Mice lack of LRG-47 display the attenuated outcome of infection with Schistosoma japonicum. Parasitol Res (2015) 0.75
Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions. PLoS One (2017) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell (2004) 12.71
Positive natural selection in the human lineage. Science (2006) 12.55
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature (2010) 10.37
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science (2006) 9.17
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Nature (1999) 8.04
Genetics and pathogenesis of inflammatory bowel disease. Nature (2011) 7.79
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science (2006) 6.25
Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science (2003) 5.50
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol (2006) 5.35
Disease tolerance as a defense strategy. Science (2012) 5.22
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage. Genome Biol (2005) 4.21
Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe (2008) 4.16
Dynamin, a membrane-remodelling GTPase. Nat Rev Mol Cell Biol (2012) 3.92
Human RAS superfamily proteins and related GTPases. Sci STKE (2004) 3.80
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet (2011) 3.59
Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. J Exp Med (2006) 3.52
Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. PLoS Pathog (2005) 3.25
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. Science (2011) 3.00
Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii. PLoS Biol (2010) 2.83
Intrinsic antiviral immunity. Nat Immunol (2012) 2.71
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science (2012) 2.69
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Cell Host Microbe (2010) 2.57
p47 GTPases: regulators of immunity to intracellular pathogens. Nat Rev Immunol (2004) 2.52
A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii. Immunity (2012) 2.50
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains. PLoS Pathog (2009) 2.35
Chlamydial IFN-gamma immune evasion is linked to host infection tropism. Proc Natl Acad Sci U S A (2005) 2.34
It takes two to tango: regulation of G proteins by dimerization. Nat Rev Mol Cell Biol (2009) 2.34
Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function. Immunity (2011) 2.33
Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity. J Interferon Cytokine Res (2010) 2.33
Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Nature (2000) 2.25
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly. Cell Microbiol (2009) 2.23
Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat Rev Immunol (2012) 2.21
Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death. PLoS Pathog (2009) 2.19
Plant and animal sensors of conserved microbial signatures. Science (2010) 2.16
IFN-inducible GTPases and immunity to intracellular pathogens. Trends Immunol (2004) 2.11
IRGM is a common target of RNA viruses that subvert the autophagy network. PLoS Pathog (2011) 2.09
A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins. PLoS Biol (2012) 2.08
Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science (2004) 2.06
Structural basis of oligomerization in the stalk region of dynamin-like MxA. Nature (2010) 2.01
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii. EMBO J (2008) 2.00
Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense. J Immunol (2007) 1.95
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole. Cell Microbiol (2010) 1.94
Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis. J Immunol (2004) 1.82
A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells. Immunity (2009) 1.82
Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages. J Immunol (2009) 1.81
Lipid domains in bacterial membranes. Mol Microbiol (2006) 1.77
Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria. Nat Cell Biol (2010) 1.76
Death and resurrection of the human IRGM gene. PLoS Genet (2009) 1.72
Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria. Nat Immunol (2009) 1.70
Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10. J Immunol (2008) 1.70
Fresh approaches to anti-infective therapies. Sci Transl Med (2012) 1.67
Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma. J Biol Chem (1996) 1.66
The interferon-inducible GTPases. Annu Rev Cell Dev Biol (2006) 1.62
Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families. Immunobiology (2007) 1.54
The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice. Proc Natl Acad Sci U S A (2006) 1.49
IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization. J Biol Chem (2003) 1.49
Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases. Mol Cell (2004) 1.48
Emerging roles for lipid droplets in immunity and host-pathogen interactions. Annu Rev Cell Dev Biol (2012) 1.42
The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response. PLoS Pathog (2012) 1.41
The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection. J Immunol (2007) 1.40
IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy. PLoS One (2009) 1.38
Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein. Hepatology (2009) 1.33
Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo. J Biol Chem (2008) 1.29
Immune control of phagosomal bacteria by p47 GTPases. Curr Opin Microbiol (2005) 1.28
IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol (2012) 1.24
IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3. J Cell Sci (2004) 1.23
Human guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma. PLoS One (2009) 1.20
In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters. J Interferon Cytokine Res (2006) 1.18
Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it. PLoS One (2011) 1.17
Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy. J Biol Chem (2011) 1.12
Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor. Proc Natl Acad Sci U S A (2005) 1.06
Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans. PLoS One (2011) 1.06
Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis. Clin Chim Acta (2010) 1.06
Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies. BMC Genomics (2008) 1.06
Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis. Mucosal Immunol (2008) 1.05
A giant GTPase, very large inducible GTPase-1, is inducible by IFNs. J Immunol (2003) 1.04
Unique features of different members of the human guanylate-binding protein family. J Interferon Cytokine Res (2007) 1.02
Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. PLoS Genet (2011) 1.02
Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner. PLoS One (2010) 1.01
A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication. FASEB J (2011) 1.00
The Salmonella SpiC protein targets the mammalian Hook3 protein function to alter cellular trafficking. Mol Microbiol (2003) 0.99
The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii. J Biol Chem (2012) 0.98
Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine. J Immunol (2010) 0.97
The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates. Mol Biol Evol (2009) 0.95
Induction of guanylate binding protein 5 by gamma interferon increases susceptibility to Salmonella enterica serovar Typhimurium-induced pyroptosis in RAW 264.7 cells. Infect Immun (2008) 0.94
NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans. Eur J Immunol (2012) 0.93
IFN-γ and TNF-α-induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling. Mucosal Immunol (2012) 0.90
Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant. FEBS J (2010) 0.84
Guanylate-binding proteins: niche recruiters for antimicrobial effectors. Immunity (2012) 0.80
New insight into the everlasting host-pathogen arms race. Nat Immunol (2009) 0.76
Immunology. Select inflammasome assembly. Science (2012) 0.76
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell (2004) 7.45
Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations. Proc Natl Acad Sci U S A (2005) 4.14
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection. Science (2011) 3.00
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science (2012) 2.69
Relation between the Widom line and the dynamic crossover in systems with a liquid-liquid phase transition. Proc Natl Acad Sci U S A (2005) 2.48
Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst. Mol Microbiol (2004) 2.26
Osteochondroma of the scapula associated with winging and large bursa formation. Med Princ Pract (2006) 1.93
Evolutionarily conserved gene family important for fat storage. Proc Natl Acad Sci U S A (2007) 1.91
A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells. Immunity (2009) 1.82
Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria. Nat Immunol (2009) 1.70
Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria. PLoS Pathog (2013) 1.59
Emerging themes in IFN-gamma-induced macrophage immunity by the p47 and p65 GTPase families. Immunobiology (2007) 1.54
Cellular self-defense: how cell-autonomous immunity protects against pathogens. Science (2013) 1.39
Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives. Eur J Med Chem (2008) 1.36
IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol (2012) 1.24
Lost salt technique for severely resorbed alveolar ridges: An innovative approach. Contemp Clin Dent (2012) 1.22
Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis. Nat Chem Biol (2013) 1.20
Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation. Mol Pharmacol (2006) 1.19
Importance of uracil DNA glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich bacteria, in mutation prevention, tolerance to acidified nitrite, and endurance in mouse macrophages. J Biol Chem (2003) 1.18
High nasopharyngeal carriage of drug resistant Streptococcus pneumoniae and Haemophilus influenzae in North Indian schoolchildren. Trop Med Int Health (2005) 1.13
An overview of post exposure prophylaxis for HIV in health care personals: Gujarat scenario. Indian J Sex Transm Dis (2011) 1.10
Multifactorial day hospital intervention to reduce falls in high risk older people in primary care: a multi-centre randomised controlled trial [ISRCTN46584556]. Trials (2006) 1.06
Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels. Mol Pharmacol (2005) 1.03
Interferon regulatory factor 8 regulates pathways for antigen presentation in myeloid cells and during tuberculosis. PLoS Genet (2011) 1.02
Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2013) 1.00
Noradrenaline vs. terlipressin in the treatment of hepatorenal syndrome: a randomized study. J Hepatol (2012) 1.00
Adiponectin inhibits leptin signalling via multiple mechanisms to exert protective effects against hepatic fibrosis. Biochem J (2011) 0.99
Cyclic AMP in mycobacteria: characterization and functional role of the Rv1647 ortholog in Mycobacterium smegmatis. J Bacteriol (2008) 0.99
Water-like solvation thermodynamics in a spherically symmetric solvent model with two characteristic lengths. Proc Natl Acad Sci U S A (2007) 0.99
Influence of acyl chain length on transfection mediated by acylated PEI nanoparticles. Int J Pharm (2006) 0.98
A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria. DNA Repair (Amst) (2007) 0.97
Linear polyethylenimine-graft-chitosan copolymers as efficient DNA/siRNA delivery vectors in vitro and in vivo. Nanomedicine (2011) 0.95
Early Infant Diagnosis: A New Tool of HIV Diagnosis in Children. Indian J Community Med (2011) 0.95
Polyethylenimine nanoparticles as efficient transfecting agents for mammalian cells. J Control Release (2005) 0.94
The evolution of guanylyl cyclases as multidomain proteins: conserved features of kinase-cyclase domain fusions. J Mol Evol (2009) 0.94
Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. Am J Physiol Gastrointest Liver Physiol (2007) 0.94
Association of IL-4 and ADAM33 gene polymorphisms with asthma in an Indian population. Lung (2010) 0.94
Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents. Microbiology (2008) 0.92
Structure of the first- and second-neighbor shells of simulated water: quantitative relation to translational and orientational order. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 0.92
Oral drug delivery systems comprising altered geometric configurations for controlled drug delivery. Int J Mol Sci (2011) 0.92
A multidisciplinary approach for management of postenucleation socket syndrome with dermis-fat graft and ocular prosthesis: a clinical report. J Prosthodont (2013) 0.91
Anaesthetic management of emergency cesarean section in a patient with holt oram syndrome. J Anaesthesiol Clin Pharmacol (2010) 0.91
Tyrphostins are inhibitors of guanylyl and adenylyl cyclases. Biochemistry (2004) 0.89
Characterization of an evolutionarily conserved metallophosphoesterase that is expressed in the fetal brain and associated with the WAGR syndrome. J Biol Chem (2008) 0.89
Etanercept improves inflammation-associated arterial stiffness in rheumatoid arthritis. Rheumatology (Oxford) (2009) 0.89
A distinct physiological role of MutY in mutation prevention in mycobacteria. Microbiology (2009) 0.89
Large scale Meta-analysis of genetic studies in ischemic stroke: Five genes involving 152,297 individuals. Indian J Hum Genet (2012) 0.88
Green tea catechin EGCG inhibits ileal apical sodium bile acid transporter ASBT. Am J Physiol Gastrointest Liver Physiol (2010) 0.88
Identification of genetic contribution to ischemic stroke by screening of single nucleotide polymorphisms in stroke patients by using a case control study design. BMC Neurol (2013) 0.87
Regulatory role of the MisR/S two-component system in hemoglobin utilization in Neisseria meningitidis. Infect Immun (2009) 0.87
Enhancement of cancer chemosensitization potential of cisplatin by tea polyphenols poly(lactide-co-glycolide) nanoparticles. J Biomed Nanotechnol (2011) 0.87
Noradrenaline vs terlipressin in the treatment of type 2 hepatorenal syndrome: a randomized pilot study. Liver Int (2013) 0.87
Treatment of phenol and cresols in upflow anaerobic sludge blanket (UASB) process: a review. Water Res (2004) 0.87
Impact assessment of mass measles vaccination. Indian J Pediatr (2002) 0.86
Preparation and Characterization of Salbutamol Sulphate Loaded Ethyl Cellulose Microspheres using Water-in-Oil-Oil Emulsion Technique. Iran J Pharm Res (2010) 0.86
Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. Acta Pol Pharm (2011) 0.86
Gellan gum blended PEI nanocomposites as gene delivery agents: evidences from in vitro and in vivo studies. Eur J Pharm Biopharm (2011) 0.85
Gold-mercaptopropionic acid-polyethylenimine composite based DNA sensor for early detection of rheumatic heart disease. Analyst (2014) 0.85
Improving the outcome of prosthetic rehabilitation following orbital exenteration. Indian J Ophthalmol (2014) 0.85
High ampicillin resistance in different biotypes and serotypes of Haemophilus influenzae colonizing the nasopharynx of healthy school-going Indian children. J Med Microbiol (2006) 0.85
Kite string: an unusual mode of maxillofacial injury. J Indian Soc Pedod Prev Dent (2013) 0.85
Effects of pressure and temperature on the binding of RecA protein to single-stranded DNA. Proc Natl Acad Sci U S A (2011) 0.84
Gene expression, biodistribution, and pharmacoscintigraphic evaluation of chondroitin sulfate-PEI nanoconstructs mediated tumor gene therapy. ACS Nano (2009) 0.84
"Polymorphisms in folate metabolism genes as maternal risk factor for neural tube defects: an updated meta-analysis". Metab Brain Dis (2014) 0.84
A composite polyelectrolytic matrix for controlled oral drug delivery. AAPS PharmSciTech (2011) 0.84
A structural basis for the role of nucleotide specifying residues in regulating the oligomerization of the Rv1625c adenylyl cyclase from M. tuberculosis. J Mol Biol (2005) 0.84
Preformulation studies for direct compression suitability of cefuroxime axetil and paracetamol: a graphical representation using SeDeM diagram. Acta Pol Pharm (2012) 0.84
Crosslinked electrospun PVA nanofibrous membranes: elucidation of their physicochemical, physicomechanical and molecular disposition. Biofabrication (2012) 0.83
Complexes of the uracil-DNA glycosylase inhibitor protein, Ugi, with Mycobacterium smegmatis and Mycobacterium tuberculosis uracil-DNA glycosylases. Microbiology (2003) 0.83
Inheritance patterns, consanguinity & risk for asthma. Indian J Med Res (2010) 0.83
The kinase homology domain of receptor guanylyl cyclase C: ATP binding and identification of an adenine nucleotide sensitive site. Biochemistry (2006) 0.83
Engineered polyallylamine nanoparticles for efficient in vitro transfection. Pharm Res (2007) 0.83
Photopic visual input is necessary for emmetropization in mice. Exp Eye Res (2013) 0.83
Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine. Microb Cell Fact (2011) 0.83
Heterocyclic chalcone analogues as potential anticancer agents. Anticancer Agents Med Chem (2013) 0.83
Soluble intercellular adhesion molecule-1 and E-selectin in patients with asthma exacerbation. Lung (2009) 0.83
IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis. Arch Toxicol (2010) 0.82
Synthesis of PLGA nanoparticles of tea polyphenols and their strong in vivo protective effect against chemically induced DNA damage. Int J Nanomedicine (2013) 0.82
Synthesis and QSAR evaluation of 2-(substituted phenyl)-1H-benzimidazoles and [2-(substituted phenyl)-benzimidazol-1-yl]-pyridin-3-yl-methanones. Eur J Med Chem (2008) 0.82
Evolution of a protein-folding machine: genomic and evolutionary analyses reveal three lineages of the archaeal hsp70(dnaK) gene. J Mol Evol (2006) 0.82
A review of integrating electroactive polymers as responsive systems for specialized drug delivery applications. J Biomed Mater Res A (2013) 0.82
Hydrogen-bond dynamics of water in a quasi-two-dimensional hydrophobic nanopore slit. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.82
Evaluation of multiple antigenic peptides based on the Chikungunya E2 protein for improved serological diagnosis of infection. Viral Immunol (2014) 0.82
The Tei index and asymptomatic myocarditis in children with severe dengue. Pediatr Cardiol (2013) 0.81
Composite polylactic-methacrylic Acid copolymer nanoparticles for the delivery of methotrexate. J Drug Deliv (2012) 0.81
Enantioselective synthesis of syn/anti-1,3-amino alcohols via proline-catalyzed sequential alpha-aminoxylation/alpha-amination and Horner-Wadsworth-Emmons olefination of aldehydes. Org Lett (2010) 0.81
Purification, crystallization and preliminary X-ray diffraction analysis of the catalytic domain of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr (2004) 0.81
Treatment of low strength complex wastewater using an anaerobic baffled reactor (ABR). Bioresour Technol (2008) 0.81
Synthesis, antimicrobial and antimycobacterial evaluation of [2-(substituted phenyl)-imidazol-1-yl]-pyridin-3-yl-methanones. J Enzyme Inhib Med Chem (2011) 0.81
Qualitative and quantitative intravaginal targeting: key to anti-HIV-1 microbicide delivery from test tube to in vivo success. J Pharm Sci (2012) 0.81
Prevalence of methylenetetrahydrofolate reductase C677T polymorphism in eastern Uttar Pradesh. Indian J Hum Genet (2012) 0.81
Occurrence of anionic surfactants in treated sewage: risk assessment to aquatic environment. J Hazard Mater (2008) 0.80
Polymeric emulsion and crosslink-mediated synthesis of super-stable nanoparticles as sustained-release anti-tuberculosis drug carriers. Colloids Surf B Biointerfaces (2011) 0.80
Formulation and evaluation of domperidone loaded mineral oil entrapped emulsion gel (MOEG) buoyant beads. Acta Pol Pharm (2011) 0.80
In vivo evaluation of a conjugated poly(lactide-ethylene glycol) nanoparticle depot formulation for prolonged insulin delivery in the diabetic rabbit model. Int J Nanomedicine (2013) 0.80
Achyranthes aspera (Apamarg) leaf extract inhibits human pancreatic tumor growth in athymic mice by apoptosis. J Ethnopharmacol (2012) 0.80