PubRank

Tomas Kirchhausen

Author PubWeight™ 117.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 2006 13.15
2 Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell 2004 6.75
3 Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature 2004 4.48
4 Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell 2003 3.75
5 Endosomal recycling controls plasma membrane area during mitosis. Proc Natl Acad Sci U S A 2007 2.86
6 Distinct dynamics of endocytic clathrin-coated pits and coated plaques. PLoS Biol 2009 2.83
7 Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe 2007 2.53
8 Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. Immunity 2009 2.50
9 Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol 2011 2.48
10 Crystal structure of the clathrin adaptor protein 1 core. Proc Natl Acad Sci U S A 2004 2.28
11 Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol 2006 2.17
12 A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating. Proc Natl Acad Sci U S A 2006 2.12
13 Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis. Immunity 2005 2.11
14 Role of lipids and actin in the formation of clathrin-coated pits. Exp Cell Res 2006 2.01
15 Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Dev Cell 2007 1.99
16 Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane. Biophys J 2007 1.85
17 Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nat Chem Biol 2005 1.84
18 The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep 2004 1.82
19 Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature 2004 1.81
20 Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proc Natl Acad Sci U S A 2002 1.67
21 Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events. J Cell Sci 2006 1.64
22 PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Mol Biol Cell 2007 1.63
23 Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nat Immunol 2011 1.57
24 The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. J Virol 2003 1.56
25 Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A 2003 1.55
26 L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. J Cell Biol 2002 1.47
27 Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. J Biol Chem 2007 1.42
28 Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly. J Cell Biol 2011 1.41
29 Roles of AP-2 in clathrin-mediated endocytosis. PLoS One 2010 1.40
30 The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis. PLoS Pathog 2010 1.40
31 An ACAP1-containing clathrin coat complex for endocytic recycling. J Cell Biol 2007 1.38
32 Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell 2012 1.34
33 Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways. Mol Biol Cell 2004 1.32
34 Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells. EMBO Rep 2004 1.28
35 Mammalian cells change volume during mitosis. PLoS One 2008 1.28
36 The transcription factor NFAT3 mediates neuronal survival. J Biol Chem 2004 1.27
37 The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites. Traffic 2002 1.27
38 Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating. Nat Struct Mol Biol 2011 1.26
39 Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis. Blood 2009 1.24
40 Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. EMBO J 2009 1.16
41 Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res 2004 1.15
42 Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation. Immunity 2013 1.11
43 Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol 2010 1.11
44 T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner. J Immunol 2003 1.09
45 Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors. J Am Chem Soc 2006 1.06
46 Effects of dynamin inactivation on pathways of anthrax toxin uptake. Eur J Cell Biol 2004 1.06
47 Redistribution of caveolae during mitosis. J Cell Sci 2011 1.05
48 Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI. Biochim Biophys Acta 2005 1.05
49 Structural analysis of the interaction between Dishevelled2 and clathrin AP-2 adaptor, a critical step in noncanonical Wnt signaling. Structure 2010 1.04
50 Structure of the PTEN-like region of auxilin, a detector of clathrin-coated vesicle budding. Structure 2010 1.03
51 Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds. J Cell Biol 2013 1.03
52 Structural biology: Conservation in vesicle coats. Nature 2010 1.03
53 Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. J Struct Biol 2006 1.01
54 HIV Nef-mediated major histocompatibility complex class I down-modulation is independent of Arf6 activity. Mol Biol Cell 2003 1.01
55 Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity. Cell Rep 2013 0.98
56 Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis. J Virol 2011 0.98
57 Uptake of rabies virus into epithelial cells by clathrin-mediated endocytosis depends upon actin. J Virol 2013 0.98
58 The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation. Cancer Res 2008 0.97
59 ARFGAP1 promotes AP-2-dependent endocytosis. Nat Cell Biol 2011 0.94
60 Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity. Biochemistry 2007 0.93
61 Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments. MBio 2012 0.91
62 Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading. Org Biomol Chem 2006 0.91
63 Chemical genetic screening identifies sulfonamides that raise organellar pH and interfere with membrane traffic. Traffic 2004 0.89
64 Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking. Traffic 2011 0.87
65 Possible role of deep tubular invaginations of the plasma membrane in MHC-I trafficking. Exp Cell Res 2005 0.84
66 Shiga toxin increases formation of clathrin-coated pits through Syk kinase. PLoS One 2010 0.83
67 Similar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin-Darby canine kidney cells. Mol Biol Cell 2013 0.82
68 The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells. Biochem Pharmacol 2006 0.81
69 Visualizing the high curvature regions of post-mitotic nascent nuclear envelope membrane. Commun Integr Biol 2012 0.76
70 Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes. Cell 2015 0.75