Published in EMBO Rep on May 21, 2004
Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis. Methods Enzymol (2008) 2.61
Shiga toxins--from cell biology to biomedical applications. Nat Rev Microbiol (2009) 2.19
In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds. PLoS Negl Trop Dis (2010) 1.72
Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER. FEMS Microbiol Lett (2006) 1.65
Golgicide A reveals essential roles for GBF1 in Golgi assembly and function. Nat Chem Biol (2009) 1.65
Retrograde transport pathways utilised by viruses and protein toxins. Virol J (2006) 1.61
Receptor-mediated oral delivery of a bioencapsulated green fluorescent protein expressed in transgenic chloroplasts into the mouse circulatory system. FASEB J (2006) 1.35
Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum. Toxins (Basel) (2010) 1.34
Cholera toxin - a foe & a friend. Indian J Med Res (2011) 1.31
Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'. Mol Biol Cell (2004) 1.26
The COG complex, Rab6 and COPI define a novel Golgi retrograde trafficking pathway that is exploited by SubAB toxin. Traffic (2009) 1.23
Intracellular phospholipase A1gamma (iPLA1gamma) is a novel factor involved in coat protein complex I- and Rab6-independent retrograde transport between the endoplasmic reticulum and the Golgi complex. J Biol Chem (2009) 1.09
Retrograde transport of protein toxins through the Golgi apparatus. Histochem Cell Biol (2013) 1.03
Ricin trafficking in plant and mammalian cells. Toxins (Basel) (2011) 0.97
Interplay between toxin transport and flotillin localization. PLoS One (2010) 0.94
Evidence that mono-ADP-ribosylation of CtBP1/BARS regulates lipid storage. Mol Biol Cell (2007) 0.92
AMF-26, a novel inhibitor of the Golgi system, targeting ADP-ribosylation factor 1 (Arf1) with potential for cancer therapy. J Biol Chem (2011) 0.91
Immunohistochemical localization of collagen type XI alpha1 and alpha2 chains in human colon tissue. J Histochem Cytochem (2007) 0.89
"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? Adv Drug Deliv Rev (2007) 0.89
Part I: an x-ray scattering study of cholera toxin penetration and induced phase transformations in lipid membranes. Biophys J (2008) 0.89
Inhibitors of the cellular trafficking of ricin. Toxins (Basel) (2012) 0.87
Retrograde traffic in the biosynthetic-secretory route. Histochem Cell Biol (2008) 0.85
The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochem J (2008) 0.85
Cholera toxin: a paradigm of a multifunctional protein. Indian J Med Res (2011) 0.83
Cholera Toxin Subunit B as Adjuvant--An Accelerator in Protective Immunity and a Break in Autoimmunity. Vaccines (Basel) (2015) 0.81
The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells. Biochem Pharmacol (2006) 0.81
Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes. J Biol Chem (2014) 0.80
The small molecule dispergo tubulates the endoplasmic reticulum and inhibits export. Mol Biol Cell (2013) 0.80
Gas phase characterization of the noncovalent quaternary structure of cholera toxin and the cholera toxin B subunit pentamer. Biophys J (2006) 0.78
Encapsulated cargo internalized by fusogenic liposomes partially overlaps the endoplasmic reticulum. J Cell Mol Med (2009) 0.76
M-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells. PLoS One (2017) 0.75
Cholera Toxin B Subunit Shows Transneuronal Tracing after Injection in an Injured Sciatic Nerve. PLoS One (2015) 0.75
Vibrio cholerae type 6 secretion system effector trafficking in target bacterial cells. Proc Natl Acad Sci U S A (2017) 0.75
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell (1989) 13.41
Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat Cell Biol (2001) 8.93
Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell (1991) 6.30
Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein. Nature (1992) 6.11
Local actin polymerization and dynamin recruitment in SV40-induced internalization of caveolae. Science (2002) 5.41
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell (2002) 4.52
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature (2003) 4.18
Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng (1990) 4.17
Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites. Nat Cell Biol (2002) 3.98
Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin. Cell (2001) 3.78
Gangliosides are receptors for murine polyoma virus and SV40. EMBO J (2003) 2.99
Rab6 coordinates a novel Golgi to ER retrograde transport pathway in live cells. J Cell Biol (1999) 2.85
The biology and enzymology of protein tyrosine O-sulfation. J Biol Chem (2003) 2.80
Gbetagamma-mediated regulation of Golgi organization is through the direct activation of protein kinase D. Cell (1999) 2.67
A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane. J Biol Chem (1996) 2.60
Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum. Nat Cell Biol (1999) 2.54
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature (1992) 2.49
Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulm. Mol Biol Cell (2003) 2.22
Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. Proc Natl Acad Sci U S A (1990) 2.12
Retrograde transport of KDEL-bearing B-fragment of Shiga toxin. J Biol Chem (1997) 2.01
The intracellular voyage of cholera toxin: going retro. Trends Biochem Sci (2003) 1.93
Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1. J Cell Biol (2002) 1.86
Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL. J Cell Biol (1995) 1.86
Phenotypic screening of small molecule libraries by high throughput cell imaging. Comb Chem High Throughput Screen (2003) 1.70
Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation. J Clin Invest (1993) 1.69
KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p. J Cell Biol (1998) 1.59
Kinase signaling initiates coat complex II (COPII) recruitment and export from the mammalian endoplasmic reticulum. J Biol Chem (2000) 1.59
Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranes. Mol Biol Cell (2001) 1.57
Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A (2003) 1.55
Evidence for the regulation of exocytic transport by protein phosphorylation. J Cell Biol (1992) 1.48
Evidence that the transport of ricin to the cytoplasm is independent of both Rab6A and COPI. J Cell Sci (2003) 0.97
Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP). J Biol Chem (2003) 0.96
Bowditch lecture. Integrated regulation of intestinal epithelial transport: intercellular and intracellular pathways. Am J Physiol (1997) 0.93
Comparison of the B-pentamers of heat-labile enterotoxin and verotoxin-1: two structures with remarkable similarity and dissimilarity. Biochemistry (1993) 0.92
Retrograde transport of protein toxins under conditions of COPI dysfunction. Biochim Biophys Acta (2002) 0.89
Accurate whole human genome sequencing using reversible terminator chemistry. Nature (2008) 90.20
Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell (2006) 13.15
Endocytosis by random initiation and stabilization of clathrin-coated pits. Cell (2004) 6.75
Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature (2004) 4.48
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi. Cell (2003) 3.75
Endosomal recycling controls plasma membrane area during mitosis. Proc Natl Acad Sci U S A (2007) 2.86
Distinct dynamics of endocytic clathrin-coated pits and coated plaques. PLoS Biol (2009) 2.83
Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity (2004) 2.79
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci (2006) 2.59
Invasive and adherent bacterial pathogens co-Opt host clathrin for infection. Cell Host Microbe (2007) 2.53
Lymphocyte crawling and transendothelial migration require chemokine triggering of high-affinity LFA-1 integrin. Immunity (2009) 2.50
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50
Actin dynamics counteract membrane tension during clathrin-mediated endocytosis. Nat Cell Biol (2011) 2.48
Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung. J Exp Med (2002) 2.32
Crystal structure of the clathrin adaptor protein 1 core. Proc Natl Acad Sci U S A (2004) 2.28
Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulm. Mol Biol Cell (2003) 2.22
The transcriptome of retinal Müller glial cells. J Comp Neurol (2008) 2.17
Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol (2006) 2.17
Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. J Clin Invest (2006) 2.16
Cortical vein air emboli with gyriform infarcts. JAMA Neurol (2013) 2.13
A burst of auxilin recruitment determines the onset of clathrin-coated vesicle uncoating. Proc Natl Acad Sci U S A (2006) 2.12
Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis. Immunity (2005) 2.11
Role of lipids and actin in the formation of clathrin-coated pits. Exp Cell Res (2006) 2.01
Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation. J Biol Chem (2003) 2.01
Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Dev Cell (2007) 1.99
The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe (2013) 1.91
Differential evanescence nanometry: live-cell fluorescence measurements with 10-nm axial resolution on the plasma membrane. Biophys J (2007) 1.85
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nat Chem Biol (2005) 1.84
Dependence of antibody-mediated presentation of antigen on FcRn. Proc Natl Acad Sci U S A (2008) 1.82
The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep (2004) 1.82
Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating. Nature (2004) 1.81
Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation. EMBO Rep (2002) 1.71
An FcRn-dependent role for anti-flagellin immunoglobulin G in pathogenesis of colitis in mice. Gastroenterology (2009) 1.71
Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway. Proc Natl Acad Sci U S A (2004) 1.69
The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity. J Cell Biol (2009) 1.68
Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI. Proc Natl Acad Sci U S A (2002) 1.67
Protein disulfide isomerase-like proteins play opposing roles during retrotranslocation. J Cell Biol (2006) 1.67
Rafting with cholera toxin: endocytosis and trafficking from plasma membrane to ER. FEMS Microbiol Lett (2006) 1.65
Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events. J Cell Sci (2006) 1.64
PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. Mol Biol Cell (2007) 1.63
Functional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulin. J Biol Chem (2002) 1.58
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nat Immunol (2011) 1.57
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. J Virol (2003) 1.56
Derlin-1 facilitates the retro-translocation of cholera toxin. Mol Biol Cell (2007) 1.55
Exo1: a new chemical inhibitor of the exocytic pathway. Proc Natl Acad Sci U S A (2003) 1.55
Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor. Mol Biol Cell (2004) 1.54
Neonatal Fc receptor: from immunity to therapeutics. J Clin Immunol (2010) 1.50
L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. J Cell Biol (2002) 1.47
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci U S A (2011) 1.44
Uncoupling of the cholera toxin-G(M1) ganglioside receptor complex from endocytosis, retrograde Golgi trafficking, and downstream signal transduction by depletion of membrane cholesterol. J Biol Chem (2002) 1.43
Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. J Biol Chem (2007) 1.42
Formation of the postmitotic nuclear envelope from extended ER cisternae precedes nuclear pore assembly. J Cell Biol (2011) 1.41
Roles of AP-2 in clathrin-mediated endocytosis. PLoS One (2010) 1.40
The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis. PLoS Pathog (2010) 1.40
An ACAP1-containing clathrin coat complex for endocytic recycling. J Cell Biol (2007) 1.38
A typology of photoreceptor gene expression patterns in the mouse. Proc Natl Acad Sci U S A (2007) 1.37
Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell (2012) 1.34
Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum. Toxins (Basel) (2010) 1.34
Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate. J Biol Chem (2005) 1.33
The HA proteins of botulinum toxin disrupt intestinal epithelial intercellular junctions to increase toxin absorption. Cell Microbiol (2007) 1.33
Cholera toxin toxicity does not require functional Arf6- and dynamin-dependent endocytic pathways. Mol Biol Cell (2004) 1.32
Fc-fusion proteins and FcRn: structural insights for longer-lasting and more effective therapeutics. Crit Rev Biotechnol (2013) 1.31
The zebrafish dag1 mutant: a novel genetic model for dystroglycanopathies. Hum Mol Genet (2011) 1.30
Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn. Semin Immunopathol (2009) 1.29
Mammalian cells change volume during mitosis. PLoS One (2008) 1.28
The genome sequence of Clostridium botulinum type C neurotoxin-converting phage and the molecular mechanisms of unstable lysogeny. Proc Natl Acad Sci U S A (2005) 1.28
The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites. Traffic (2002) 1.27
The transcription factor NFAT3 mediates neuronal survival. J Biol Chem (2004) 1.27
Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating. Nat Struct Mol Biol (2011) 1.26
Attenuated endocytosis and toxicity of a mutant cholera toxin with decreased ability to cluster ganglioside GM1 molecules. Infect Immun (2008) 1.20
Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2. J Clin Invest (2010) 1.19
TorsinA participates in endoplasmic reticulum-associated degradation. Nat Commun (2011) 1.18
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes. Proc Natl Acad Sci U S A (2011) 1.16
Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. EMBO J (2009) 1.16
Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine. Pediatr Res (2003) 1.16
Streptolysin S contributes to group A streptococcal translocation across an epithelial barrier. J Biol Chem (2010) 1.16
Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide. J Lipid Res (2004) 1.15
Functional analysis of VopF activity required for colonization in Vibrio cholerae. MBio (2010) 1.14
Botulinum hemagglutinin disrupts the intercellular epithelial barrier by directly binding E-cadherin. J Cell Biol (2010) 1.14
Disruption of the epithelial barrier by botulinum haemagglutinin (HA) proteins - differences in cell tropism and the mechanism of action between HA proteins of types A or B, and HA proteins of type C. Microbiology (2009) 1.12
Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation. Immunity (2013) 1.11
Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN. Nat Cell Biol (2010) 1.11
T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner. J Immunol (2003) 1.09
Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1. Dev Cell (2012) 1.09
Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors. J Am Chem Soc (2006) 1.06
Effects of dynamin inactivation on pathways of anthrax toxin uptake. Eur J Cell Biol (2004) 1.06
The immunologic functions of the neonatal Fc receptor for IgG. J Clin Immunol (2012) 1.06
N-terminal extension of the cholera toxin A1-chain causes rapid degradation after retrotranslocation from endoplasmic reticulum to cytosol. J Biol Chem (2010) 1.05
Redistribution of caveolae during mitosis. J Cell Sci (2011) 1.05
Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI. Biochim Biophys Acta (2005) 1.05
Crystal structure of Clostridium botulinum whole hemagglutinin reveals a huge triskelion-shaped molecular complex. J Biol Chem (2013) 1.05
Structural analysis of the interaction between Dishevelled2 and clathrin AP-2 adaptor, a critical step in noncanonical Wnt signaling. Structure (2010) 1.04