Published in BMC Genet on December 30, 2005
Genomewide rapid association using mixed model and regression: a fast and simple method for genomewide pedigree-based quantitative trait loci association analysis. Genetics (2007) 7.09
A genomic background based method for association analysis in related individuals. PLoS One (2007) 3.46
Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes (2009) 1.91
The epithelial sodium channel γ-subunit gene and blood pressure: family based association, renal gene expression, and physiological analyses. Hypertension (2011) 1.50
Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study. Atherosclerosis (2013) 1.48
RNA-Seq identifies SNP markers for growth traits in rainbow trout. PLoS One (2012) 1.25
Chemerin, a novel adipokine in the regulation of angiogenesis. J Clin Endocrinol Metab (2010) 1.20
A rapid generalized least squares model for a genome-wide quantitative trait association analysis in families. Hum Hered (2011) 1.14
Overview of techniques to account for confounding due to population stratification and cryptic relatedness in genomic data association analyses. Heredity (Edinb) (2010) 1.11
Development of structural MR brain imaging protocols to study genetics and maturation. Methods (2009) 1.07
A chromosome 11q quantitative-trait locus influences change of blood-pressure measurements over time in Mexican Americans of the San Antonio Family Heart Study. Am J Hum Genet (2007) 1.04
Genome-wide association studies and the genetic dissection of complex traits. Am J Hematol (2009) 1.04
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2010) 1.03
Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study. Am J Epidemiol (2013) 1.03
Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Circ Cardiovasc Genet (2009) 1.01
The association of the MYH9 gene and kidney outcomes in American Indians: the Strong Heart Family Study. Hum Genet (2010) 0.96
Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia. Mol Hum Reprod (2009) 0.90
Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans. Arterioscler Thromb Vasc Biol (2009) 0.90
Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians. Eur J Hum Genet (2013) 0.88
The association of genetic variants of type 2 diabetes with kidney function. Kidney Int (2012) 0.87
Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels. Circ Cardiovasc Genet (2009) 0.87
Baboons as a model to study genetics and epigenetics of human disease. ILAR J (2013) 0.87
Genetic associations between neuregulin-1 SNPs and neurocognitive function in multigenerational, multiplex schizophrenia families. Psychiatr Genet (2012) 0.86
Genetic variants in the renin-angiotensin system genes are associated with cardiovascular-renal-related risk factors in Mexican Americans. Hum Genet (2008) 0.86
Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2. Invest Ophthalmol Vis Sci (2013) 0.86
The 27-bp repeat polymorphism in intron 4 (27 bp-VNTR) of endothelial nitric oxide synthase (eNOS) gene is associated with albumin to creatinine ratio in Mexican Americans. Mol Cell Biochem (2009) 0.85
A three-stage approach for genome-wide association studies with family data for quantitative traits. BMC Genet (2010) 0.84
Genetic variation in PARL influences mitochondrial content. Hum Genet (2009) 0.83
Generalization of associations of kidney-related genetic loci to American Indians. Clin J Am Soc Nephrol (2013) 0.82
Evaluation of polymorphisms in paraoxonase 2 (PON2) gene and their association with cardiovascular-renal disease risk in Mexican Americans. Kidney Blood Press Res (2009) 0.82
Serum uric acid concentrations and SLC2A9 genetic variation in Hispanic children: the Viva La Familia Study. Am J Clin Nutr (2015) 0.82
Summary of contributions to GAW Group 15: family-based samples are useful in identifying common polymorphisms associated with complex traits. Genet Epidemiol (2009) 0.82
Molecular prioritization strategies to identify functional genetic variants in the cardiovascular disease-associated expression QTL Vanin-1. Eur J Hum Genet (2013) 0.81
Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans. Arterioscler Thromb Vasc Biol (2012) 0.81
Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q. PLoS One (2010) 0.81
High resolution linkage and linkage disequilibrium analyses of chromosome 1p36 SNPs identify new positional candidate genes for low bone mineral density. Osteoporos Int (2008) 0.80
A comparative study of three methods for detecting association of quantitative traits in samples of related subjects. BMC Proc (2009) 0.79
Genetics of kidney disease and related cardiometabolic phenotypes in Zuni Indians: the Zuni Kidney Project. Front Genet (2015) 0.77
Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families. J Neurodev Disord (2017) 0.75
A Major Locus for Quantitatively Measured Shank Skin Color Traits in Korean Native Chicken. Asian-Australas J Anim Sci (2016) 0.75
Mapping of a blood pressure QTL on chromosome 17 in American Indians of the strong heart family study. BMC Cardiovasc Disord (2014) 0.75
Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97
A general test of association for quantitative traits in nuclear families. Am J Hum Genet (2000) 22.45
Combined linkage and association sib-pair analysis for quantitative traits. Am J Hum Genet (1999) 11.22
Markov chain Monte Carlo segregation and linkage analysis for oligogenic models. Am J Hum Genet (1997) 10.86
Extensions to multivariate normal models for pedigree analysis. Ann Hum Genet (1982) 7.07
Pedigree tests of transmission disequilibrium. Eur J Hum Genet (2000) 5.93
MCMC segregation and linkage analysis. Genet Epidemiol (1997) 3.11
Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism. Genet Epidemiol (1999) 2.01
Combined linkage and association analysis in pedigrees. Genet Epidemiol (2001) 1.12
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology Study. Diabetes (2006) 3.67
Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage (2009) 3.66
A comprehensive linkage analysis for myocardial infarction and its related risk factors. Nat Genet (2002) 3.19
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am J Psychiatry (2007) 2.84
Genetic and environmental factors influencing the human factor H plasma levels. Immunogenetics (2004) 2.43
Neuroimaging endophenotypes: strategies for finding genes influencing brain structure and function. Hum Brain Mapp (2007) 2.36
High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry (2011) 2.23
Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican-americans. Diabetes (2002) 2.06
Genetic variation in selenoprotein S influences inflammatory response. Nat Genet (2005) 2.00
Estimating the additive genetic effect of the X chromosome. Genet Epidemiol (2005) 1.95
Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes (2009) 1.91
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
Heritability of age at menarche in girls from the Fels Longitudinal Study. Am J Phys Anthropol (2005) 1.81
Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT project. Thromb Haemost (2003) 1.80
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage (2013) 1.78
Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study. Diabetes (2005) 1.72
Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population. J Clin Endocrinol Metab (2009) 1.72
Long-term changes in adiposity and glycemic control are associated with past adenovirus infection. Diabetes Care (2012) 1.63
Amygdalar and hippocampal substrates of anxious temperament differ in their heritability. Nature (2010) 1.63
On the genetic architecture of cortical folding and brain volume in primates. Neuroimage (2010) 1.62
Quantitative trait nucleotide analysis using Bayesian model selection. Hum Biol (2005) 1.60
A genomewide search finds major susceptibility loci for gallbladder disease on chromosome 1 in Mexican Americans. Am J Hum Genet (2006) 1.59
Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res (2012) 1.58
A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. Diabetes (2005) 1.52
Plasma lipidomic profile signature of hypertension in Mexican American families: specific role of diacylglycerols. Hypertension (2013) 1.51
Increased collagen content in insulin-resistant skeletal muscle. Am J Physiol Endocrinol Metab (2005) 1.49
Adjudicating neurocognitive endophenotypes for schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2007) 1.48
A quantitative trait locus influencing free plasma protein S levels on human chromosome 1q: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) project. Arterioscler Thromb Vasc Biol (2003) 1.48
Heritability of brain volume, surface area and shape: an MRI study in an extended pedigree of baboons. Hum Brain Mapp (2007) 1.47
A genome search for genetic determinants that influence plasma fibrinogen levels. Arterioscler Thromb Vasc Biol (2005) 1.47
Quantitative trait nucleotide analysis using Bayesian model selection. 2005. Hum Biol (2009) 1.46
Variance component methods for analysis of complex phenotypes. Cold Spring Harb Protoc (2010) 1.44
The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus. 2005. Hum Biol (2009) 1.43
The functional connectivity of the human caudate: an application of meta-analytic connectivity modeling with behavioral filtering. Neuroimage (2011) 1.41
Quantitative loci regulating plasma levels of gamma glutamyl transferase and albumin and their genetic correlations with cardiovascular risk factors. Exp Biol Med (Maywood) (2009) 1.39
Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet (2013) 1.39
Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits. BMC Proc (2007) 1.36
Plasma lipid profiling in a large population-based cohort. J Lipid Res (2013) 1.35
Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases. Genet Epidemiol (2002) 1.34
The baboon as a nonhuman primate model for the study of the genetics of obesity. Obes Res (2003) 1.34
Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring) (2007) 1.32
SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes (2007) 1.30
Genes on chromosomes 1 and 13 have significant effects on Ascaris infection. Proc Natl Acad Sci U S A (2002) 1.28
Measuring and comparing brain cortical surface area and other areal quantities. Neuroimage (2012) 1.27
Genome scan for determinants of serum uric acid variability. J Am Soc Nephrol (2007) 1.25
Quantitative trait loci on chromosomes 2p, 4p, and 13q influence bone mineral density of the forearm and hip in Mexican Americans. J Bone Miner Res (2003) 1.25
A kernel of truth: statistical advances in polygenic variance component models for complex human pedigrees. Adv Genet (2013) 1.25
Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes (2007) 1.25
Plasma lipid profiling shows similar associations with prediabetes and type 2 diabetes. PLoS One (2013) 1.24
Analysis of genetic variability and whole genome linkage of whole-brain, subcortical, and ependymal hyperintense white matter volume. Stroke (2009) 1.24
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. Am J Hum Genet (2002) 1.23
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Hum Mol Genet (2013) 1.23
A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels. Blood (2007) 1.22
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes. BMC Med Genomics (2010) 1.22
Testing the hypothesis of accelerated cerebral white matter aging in schizophrenia and major depression. Biol Psychiatry (2012) 1.21
Linkage analysis without defined pedigrees. Genet Epidemiol (2011) 1.20
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations. Hum Genet (2009) 1.20
Chemerin, a novel adipokine in the regulation of angiogenesis. J Clin Endocrinol Metab (2010) 1.20
Effects of genes, sex, age, and activity on BMC, bone size, and areal and volumetric BMD. J Bone Miner Res (2007) 1.18
The path to open-angle glaucoma gene discovery: endophenotypic status of intraocular pressure, cup-to-disc ratio, and central corneal thickness. Invest Ophthalmol Vis Sci (2010) 1.18
Large scale mitochondrial sequencing in Mexican Americans suggests a reappraisal of Native American origins. BMC Evol Biol (2011) 1.16
Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. J Bone Miner Res (2013) 1.16
A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project. Am J Hum Genet (2005) 1.15
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). PLoS Genet (2013) 1.15
A second-generation genetic linkage map of the baboon (Papio hamadryas) genome. Genomics (2006) 1.15
Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans. Nat Genet (2001) 1.14