Published in Genet Epidemiol on January 01, 2002
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65
A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet (2002) 1.91
Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52
Gene-gene interaction between RBMS3 and ZNF516 influences bone mineral density. J Bone Miner Res (2013) 1.45
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. PLoS Genet (2010) 1.41
Bayesian mapping of quantitative trait loci for multiple complex traits with the use of variance components. Am J Hum Genet (2007) 1.35
Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction. J Bone Miner Res (2006) 1.24
Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study. J Bone Miner Res (2010) 1.09
Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures. Calcif Tissue Int (2008) 1.08
Genetics of the musculoskeletal system: a pleiotropic approach. J Bone Miner Res (2008) 1.06
Evidence for pleiotropic factors in genetics of the musculoskeletal system. Bone (2010) 1.06
Searching for osteoporosis genes in the post-genome era: progress and challenges. Osteoporos Int (2003) 1.05
Genetic contribution to biological aging: the Framingham Study. J Gerontol A Biol Sci Med Sci (2004) 1.00
A genome-wide linkage scan for bone mineral density in an extended sample: evidence for linkage on 11q23 and Xq27. J Med Genet (2004) 1.00
Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations. J Bone Miner Res (2011) 0.99
Genetic epidemiology of age-related osteoporosis and its clinical applications. Nat Rev Rheumatol (2010) 0.99
Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density. Proteomics (2008) 0.94
IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study. J Bone Miner Res (2010) 0.92
Chromosomal regions 22q13 and 3p25 may harbor quantitative trait loci influencing both age at menarche and bone mineral density. Hum Genet (2008) 0.91
Genome-wide Association Studies for Osteoporosis: A 2013 Update. J Bone Metab (2014) 0.90
An integrative study ascertained SOD2 as a susceptibility gene for osteoporosis in Chinese. J Bone Miner Res (2011) 0.89
Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk. Sci Rep (2016) 0.88
Mitochondria-wide association study of common variants in osteoporosis. Ann Hum Genet (2011) 0.87
Identification of genes for complex diseases using integrated analysis of multiple types of genomic data. PLoS One (2012) 0.86
Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study. J Bone Miner Res (2012) 0.86
Genetic studies in osteoporosis--the end of the beginning. Arthritis Res Ther (2008) 0.86
Unique and common genetic effects between bone mineral density and calcaneal quantitative ultrasound measures: the Fels Longitudinal Study. Osteoporos Int (2006) 0.83
A polymorphism at the translation start site of the vitamin D receptor gene is associated with the response to anti-osteoporotic therapy in postmenopausal women from southern Italy. Int J Mol Sci (2015) 0.82
Choice of study phenotype in osteoporosis genetic research. J Bone Miner Metab (2009) 0.82
A whole genome linkage scan for QTLs underlying peak bone mineral density. Osteoporos Int (2007) 0.80
Searching for genes underlying susceptibility to osteoporotic fracture: current progress and future prospect. Osteoporos Int (2007) 0.78
Sister's fracture history may be associated with perimenopausal bone fragility and modifies the predictability of fracture risk. Osteoporos Int (2008) 0.78
Comparison of whole genome linkage scans in premenopausal and postmenopausal women: no bone-loss-specific QTLs were implicated. Osteoporos Int (2008) 0.77
Are bone mineral density loci associated with hip osteoporotic fractures? A validation study on previously reported genome-wide association loci in a Chinese population. Genet Mol Res (2012) 0.76
Osteoporosis genetics: year 2011 in review. Bonekey Rep (2012) 0.76
No association between polymorphisms and haplotypes of COL1A1 and COL1A2 genes and osteoporotic fracture in postmenopausal Chinese women. Acta Pharmacol Sin (2011) 0.76
Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families. J Bone Miner Res (2016) 0.75
Contribution of Genetic Background and Clinical Risk Factors to Low-Trauma Fractures in Human Immunodeficiency Virus (HIV)-Positive Persons: The Swiss HIV Cohort Study. Open Forum Infect Dis (2016) 0.75
BMP7 gene polymorphisms are not associated with bone mineral density or osteoporotic fractures in postmenopausal Chinese women. Acta Pharmacol Sin (2016) 0.75
A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women. Bone Rep (2016) 0.75
Genome sequencing in microfabricated high-density picolitre reactors. Nature (2005) 150.21
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nat Biotechnol (2009) 9.67
Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr (2007) 9.61
Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell (2011) 7.30
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet (2001) 6.56
Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr (2003) 6.50
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med (2011) 6.35
Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res (2013) 5.93
Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol Cell (2010) 5.77
Global diversity in the human salivary microbiome. Genome Res (2009) 5.16
Metabolite identification via the Madison Metabolomics Consortium Database. Nat Biotechnol (2008) 5.12
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res (2011) 4.55
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest (2008) 4.12
Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Ann Neurol (2011) 4.09
Modification of kidney barrier function by the urokinase receptor. Nat Med (2007) 4.01
High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia. J Infect Dis (2010) 3.81
Exchange-coupled nanocomposite magnets by nanoparticle self-assembly. Nature (2002) 3.71
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites. Mol Biol Evol (2003) 3.67
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation. Nature (2007) 3.55
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum Mol Genet (2008) 3.24
Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med (2011) 3.19
Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (2013) 3.17
Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the fullPIERS model. Lancet (2010) 3.15
Wnt/beta-catenin signaling is a normal physiological response to mechanical loading in bone. J Biol Chem (2006) 3.10
Comparison of the effect of denosumab and alendronate on BMD and biochemical markers of bone turnover in postmenopausal women with low bone mass: a randomized, blinded, phase 3 trial. J Bone Miner Res (2009) 2.99
Circulating suPAR in two cohorts of primary FSGS. J Am Soc Nephrol (2012) 2.83
Intravenous ibandronate injections in postmenopausal women with osteoporosis: one-year results from the dosing intravenous administration study. Arthritis Rheum (2006) 2.82
Whole-brain radiotherapy in the management of brain metastasis. J Clin Oncol (2006) 2.76
Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med (2005) 2.72
Relationship of obesity with osteoporosis. J Clin Endocrinol Metab (2007) 2.71
American Association of Clinical Endocrinologists medical guidelines for clinical practice for the prevention and treatment of postmenopausal osteoporosis: 2001 edition, with selected updates for 2003. Endocr Pract (2004) 2.69
Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis. Am J Hum Genet (2008) 2.65
Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients. J Infect Dis (2012) 2.53
Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proc Natl Acad Sci U S A (2003) 2.50
Contrasting genetic structure in Plasmodium vivax populations from Asia and South America. Int J Parasitol (2007) 2.41
N-Benzyl-2-(2,6-dichloro-phen-oxy)-acetamide. Acta Crystallogr Sect E Struct Rep Online (2008) 2.36
Induction of TRPC6 channel in acquired forms of proteinuric kidney disease. J Am Soc Nephrol (2006) 2.32
Control of the pattern-recognition receptor EFR by an ER protein complex in plant immunity. EMBO J (2009) 2.28
Clinical value of monitoring BMD in patients treated with bisphosphonates for osteoporosis. J Bone Miner Res (2009) 2.24
Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab (2011) 2.22
Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci U S A (2007) 2.20
Project management system for structural and functional proteomics: Sesame. J Struct Funct Genomics (2003) 2.19
New bioinformatics resources for metabolomics. Pac Symp Biocomput (2007) 2.19
Regulation of human airway epithelial cell IL-8 expression by MAP kinases. Am J Physiol Lung Cell Mol Physiol (2002) 2.19
Bone remodeling increases substantially in the years after menopause and remains increased in older osteoporosis patients. J Bone Miner Res (2004) 2.14
Effects of vacuum-assisted closure on wound microcirculation: an experimental study. Asian J Surg (2005) 2.14
Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet (2009) 2.14
A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Circ Res (2006) 2.12
Generation of functional ion-channel tools by E3 targeting. Nat Biotechnol (2005) 2.08
The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp Diabetes Res (2009) 2.08
Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice. Haematologica (2007) 2.07
Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease. Environ Health Perspect (2012) 2.05
Learning brain connectivity of Alzheimer's disease by sparse inverse covariance estimation. Neuroimage (2010) 2.04
A phosphorylation state-specific antibody recognizes Hsp27, a novel substrate of protein kinase D. J Biol Chem (2005) 2.03
Vitamin D(3) is more potent than vitamin D(2) in humans. J Clin Endocrinol Metab (2010) 2.02
Synthesis and functional analyses of nuclear clusterin, a cell death protein. J Biol Chem (2003) 2.01
Expression of midkine and endoglin in breast carcinomas with different immunohistochemical profiles. APMIS (2010) 2.00
Genetic variation in selenoprotein S influences inflammatory response. Nat Genet (2005) 2.00
Effect of otitis media with effusion and its clinical intervention on the development of mastoid in children. Acta Otolaryngol (2014) 1.98
The quantitative trait linkage disequilibrium test: a more powerful alternative to the quantitative transmission disequilibrium test for use in the absence of population stratification. BMC Genet (2005) 1.98
TRPC channel activation by extracellular thioredoxin. Nature (2008) 1.97
Odanacatib, a cathepsin-K inhibitor for osteoporosis: a two-year study in postmenopausal women with low bone density. J Bone Miner Res (2010) 1.95
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem (2005) 1.95
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX. Proc Natl Acad Sci U S A (2009) 1.94
A genomewide linkage scan for quantitative-trait loci for obesity phenotypes. Am J Hum Genet (2002) 1.91
Thermal difference spectra: a specific signature for nucleic acid structures. Nucleic Acids Res (2005) 1.91
Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study. J Clin Endocrinol Metab (2013) 1.88
Phase I study of ON 01910.Na, a novel modulator of the Polo-like kinase 1 pathway, in adult patients with solid tumors. J Clin Oncol (2008) 1.84
A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase. Biochemistry (2002) 1.81
Using spatial principles to optimize distributed computing for enabling the physical science discoveries. Proc Natl Acad Sci U S A (2011) 1.81
Monthly oral ibandronate therapy in postmenopausal osteoporosis: 1-year results from the MOBILE study. J Bone Miner Res (2005) 1.81
Chinese authors do need CONSORT: reporting quality assessment for five leading Chinese medical journals. Contemp Clin Trials (2008) 1.80
HIV incidence among men who have sex with men in China: a meta-analysis of published studies. PLoS One (2011) 1.79
Chlorophyllase 1, a damage control enzyme, affects the balance between defense pathways in plants. Plant Cell (2004) 1.76
Extracellular protein disulfide isomerase regulates ligand-binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation. Blood (2013) 1.75
EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells. PLoS One (2011) 1.73
Beta-AMYLASE4, a noncatalytic protein required for starch breakdown, acts upstream of three active beta-amylases in Arabidopsis chloroplasts. Plant Cell (2008) 1.72
Proliferation and differentiation of bone marrow stromal cells under hypoxic conditions. Biochem Biophys Res Commun (2006) 1.72
Spontaneous heart disease in the adult chimpanzee (Pan troglodytes). J Med Primatol (2008) 1.72
Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population. J Clin Endocrinol Metab (2009) 1.72
Mutation patterns at dinucleotide microsatellite loci in humans. Am J Hum Genet (2002) 1.71
The WRKY family of transcription factors in rice and Arabidopsis and their origins. DNA Res (2005) 1.70
Inferred relatedness and heritability in malaria parasites. Proc Biol Sci (2010) 1.69
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons. Nat Neurosci (2011) 1.66
Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Nat Commun (2013) 1.65
A mixed-valence copper coordination polymer generated by hydrothermal metal/ligand redox reactions. Chem Commun (Camb) (2002) 1.65
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Photoperiod- and thermo-sensitive genic male sterility in rice are caused by a point mutation in a novel noncoding RNA that produces a small RNA. Cell Res (2012) 1.63
Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer. Clin Cancer Res (2009) 1.61
Trabecular bone histomorphometry in humans with Type 1 Diabetes Mellitus. Bone (2011) 1.61
Bone microarchitecture and stiffness in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab (2009) 1.61
Quantitative trait nucleotide analysis using Bayesian model selection. Hum Biol (2005) 1.60
Girls on a high-calcium diet gain weight at the same rate as girls on a normal diet: a pilot study. J Am Diet Assoc (2004) 1.60
Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop. J Bone Miner Res (2009) 1.59