Published in Hum Biol on October 01, 2005
Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes (2009) 1.91
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage (2013) 1.78
Variance component methods for analysis of complex phenotypes. Cold Spring Harb Protoc (2010) 1.44
A kernel of truth: statistical advances in polygenic variance component models for complex human pedigrees. Adv Genet (2013) 1.25
A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels. Blood (2007) 1.22
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations. Hum Genet (2009) 1.20
Chemerin, a novel adipokine in the regulation of angiogenesis. J Clin Endocrinol Metab (2010) 1.20
Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study). Eur J Hum Genet (2008) 1.08
Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children. Am J Clin Nutr (2009) 1.07
Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. Mol Psychiatry (2011) 1.01
Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. Neuroimage (2014) 0.98
Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels. Hum Mol Genet (2009) 0.89
Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos. Am J Clin Nutr (2010) 0.89
The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling. Diabetes (2012) 0.89
Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos. Front Genet (2012) 0.89
Replication of the effect of SLC2A9 genetic variation on serum uric acid levels in American Indians. Eur J Hum Genet (2013) 0.88
A critical assessment of the factors affecting reporter gene assays for promoter SNP function: a reassessment of -308 TNF polymorphism function using a novel integrated reporter system. Eur J Hum Genet (2009) 0.88
Two quantitative trait loci influence whipworm (Trichuris trichiura) infection in a Nepalese population. J Infect Dis (2008) 0.88
Genome-wide discovery of maternal effect variants. BMC Proc (2009) 0.88
Genetic effects on DNA methylation and its potential relevance for obesity in Mexican Americans. PLoS One (2013) 0.86
Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. Obesity (Silver Spring) (2012) 0.86
Bivariate association analysis of longitudinal phenotypes in families. BMC Proc (2014) 0.85
Genetic dissection of the pre-eclampsia susceptibility locus on chromosome 2q22 reveals shared novel risk factors for cardiovascular disease. Mol Hum Reprod (2013) 0.84
Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans. J Hypertens (2009) 0.84
Genetic variation in PARL influences mitochondrial content. Hum Genet (2009) 0.83
Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels. Physiol Genomics (2010) 0.81
Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q. PLoS One (2010) 0.81
Association of genetic variation in ENPP1 with obesity-related phenotypes. Obesity (Silver Spring) (2008) 0.80
Plasma levels of soluble interleukin 1 receptor accessory protein are reduced in obesity. J Clin Endocrinol Metab (2014) 0.79
Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study. BMC Proc (2009) 0.79
Genetic mapping of vascular calcified plaque loci on chromosome 16p in European Americans from the diabetes heart study. Ann Hum Genet (2011) 0.78
Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children. Physiol Genomics (2011) 0.77
Genome-wide scan identifies a quantitative trait locus at 4p15.3 for serum urate. Eur J Hum Genet (2010) 0.77
Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate. J Headache Pain (2011) 0.77
The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome. Metabolism (2009) 0.77
Mapping of a blood pressure QTL on chromosome 17 in American Indians of the strong heart family study. BMC Cardiovasc Disord (2014) 0.75
Lack of Association between SLC30A8 Variants and Type 2 Diabetes in Mexican American Families. J Diabetes Res (2016) 0.75
Association of TMTC2 With Human Nonsyndromic Sensorineural Hearing Loss. JAMA Otolaryngol Head Neck Surg (2016) 0.75
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet (2007) 11.09
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
Inhibitors of factor VIII in black patients with hemophilia. N Engl J Med (2009) 4.82
High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia. J Infect Dis (2010) 3.81
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites. Mol Biol Evol (2003) 3.67
Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage (2009) 3.66
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Genome-wide association study of alcohol dependence implicates a region on chromosome 11. Alcohol Clin Exp Res (2010) 2.99
Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia. Am J Psychiatry (2007) 2.84
Association of alcohol dehydrogenase genes with alcohol dependence: a comprehensive analysis. Hum Mol Genet (2006) 2.49
Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A (2002) 2.47
Genetic and environmental factors influencing the human factor H plasma levels. Immunogenetics (2004) 2.43
Contrasting genetic structure in Plasmodium vivax populations from Asia and South America. Int J Parasitol (2007) 2.41
The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behav Genet (2006) 2.26
High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry (2011) 2.23
Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biol Psychol (2002) 2.08
Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican-americans. Diabetes (2002) 2.06
Genetic variation in selenoprotein S influences inflammatory response. Nat Genet (2005) 2.00
The quantitative trait linkage disequilibrium test: a more powerful alternative to the quantitative transmission disequilibrium test for use in the absence of population stratification. BMC Genet (2005) 1.98
Estimating the additive genetic effect of the X chromosome. Genet Epidemiol (2005) 1.95
Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes (2009) 1.91
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging Behav (2014) 1.90
A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biol Psychiatry (2008) 1.88
Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT project. Thromb Haemost (2003) 1.80
Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition. Int J Psychophysiol (2004) 1.79
Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychol Sci (2010) 1.78
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage (2013) 1.78
Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2002) 1.76
Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study. Diabetes (2005) 1.72
Spontaneous heart disease in the adult chimpanzee (Pan troglodytes). J Med Primatol (2008) 1.72
Inferred relatedness and heritability in malaria parasites. Proc Biol Sci (2010) 1.69
Amygdalar and hippocampal substrates of anxious temperament differ in their heritability. Nature (2010) 1.63
Linkage analysis of glomerular filtration rate in American Indians. Kidney Int (2008) 1.59
A genomewide search finds major susceptibility loci for gallbladder disease on chromosome 1 in Mexican Americans. Am J Hum Genet (2006) 1.59
Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites. Mol Biol Evol (2005) 1.56
A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. Diabetes (2005) 1.52
Plasma lipidomic profile signature of hypertension in Mexican American families: specific role of diacylglycerols. Hypertension (2013) 1.51
Neurocognitive endophenotypes for bipolar disorder identified in multiplex multigenerational families. Arch Gen Psychiatry (2010) 1.50
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. Am J Hum Genet (2005) 1.49
Adjudicating neurocognitive endophenotypes for schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2007) 1.48
A genome search for genetic determinants that influence plasma fibrinogen levels. Arterioscler Thromb Vasc Biol (2005) 1.47
Quantitative trait nucleotide analysis using Bayesian model selection. 2005. Hum Biol (2009) 1.46
Variance component methods for analysis of complex phenotypes. Cold Spring Harb Protoc (2010) 1.44
The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus. 2005. Hum Biol (2009) 1.43
Linkage of the cholesterol 7alpha-hydroxylase gene and low-density lipoprotein cholesterol conditional on apolipoprotein E association: the National Heart, Lung, and Blood Institute Family Heart Study. Chin Med J (Engl) (2005) 1.42
Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction. J Stud Alcohol (2006) 1.42
Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits. BMC Proc (2007) 1.36
Plasma lipid profiling in a large population-based cohort. J Lipid Res (2013) 1.35
Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases. Genet Epidemiol (2002) 1.34
Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behav Genet (2005) 1.32
Heritability of left ventricular dimensions and mass in American Indians: The Strong Heart Study. J Hypertens (2004) 1.30
Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. Alcohol Res Health (2002) 1.27
A kernel of truth: statistical advances in polygenic variance component models for complex human pedigrees. Adv Genet (2013) 1.25
Quantitative trait loci on chromosomes 2p, 4p, and 13q influence bone mineral density of the forearm and hip in Mexican Americans. J Bone Miner Res (2003) 1.25
Plasma lipid profiling shows similar associations with prediabetes and type 2 diabetes. PLoS One (2013) 1.24
Analysis of genetic variability and whole genome linkage of whole-brain, subcortical, and ependymal hyperintense white matter volume. Stroke (2009) 1.24
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. Am J Hum Genet (2002) 1.23
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. Hum Mol Genet (2013) 1.23
A novel missense mutation in the transmembrane domain of neuregulin 1 is associated with schizophrenia. Biol Psychiatry (2006) 1.23
A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels. Blood (2007) 1.22
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes. BMC Med Genomics (2010) 1.22
Linkage analysis without defined pedigrees. Genet Epidemiol (2011) 1.20
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations. Hum Genet (2009) 1.20
Chemerin, a novel adipokine in the regulation of angiogenesis. J Clin Endocrinol Metab (2010) 1.20
A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project. Am J Hum Genet (2005) 1.15
A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). PLoS Genet (2013) 1.15
Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans. Nat Genet (2001) 1.14
A multimodal assessment of the genetic control over working memory. J Neurosci (2010) 1.14