Published in J Biol Chem on February 09, 2006
The expanding universe of p53 targets. Nat Rev Cancer (2009) 3.49
The rebel angel: mutant p53 as the driving oncogene in breast cancer. Carcinogenesis (2012) 1.67
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer. Cancer Res (2011) 1.21
Roles of estrogen receptor alpha and beta in modulating urothelial cell proliferation. Endocr Relat Cancer (2008) 1.20
A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation. Breast Cancer Res (2011) 1.16
Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM. Mol Cell Biol (2009) 1.15
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. Mol Cell Biol (2007) 1.13
Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences. Proc Natl Acad Sci U S A (2010) 1.11
Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation. Proc Natl Acad Sci U S A (2010) 1.07
Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide. Neuro Oncol (2010) 1.04
miRNA-34b as a tumor suppressor in estrogen-dependent growth of breast cancer cells. Breast Cancer Res (2011) 1.03
Prognostic interaction between expression of p53 and estrogen receptor in patients with node-negative breast cancer: results from IBCSG Trials VIII and IX. Breast Cancer Res (2012) 0.98
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics. Cell Cycle (2013) 0.98
Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias. Blood (2010) 0.98
Ligand-independent antiapoptotic function of estrogen receptor-beta in lung cancer cells. Mol Endocrinol (2010) 0.97
Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy. Breast Cancer Res Treat (2008) 0.96
Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay. PLoS One (2011) 0.94
Estrogen receptor α in cancer-associated fibroblasts suppresses prostate cancer invasion via modulation of thrombospondin 2 and matrix metalloproteinase 3. Carcinogenesis (2013) 0.92
Three assays show differences in binding of wild-type and mutant p53 to unique gene sequences. Technol Cancer Res Treat (2009) 0.89
Estrogen-mediated upregulation of Noxa is associated with cell cycle progression in estrogen receptor-positive breast cancer cells. PLoS One (2011) 0.88
P53 genotype as a determinant of ER expression and tamoxifen response in the MMTV-Wnt-1 model of mammary carcinogenesis. Breast Cancer Res Treat (2010) 0.88
Transcriptional inhibition of p21WAF1/CIP1 gene (CDKN1) expression by survivin is at least partially p53-dependent: evidence for survivin acting as a transcription factor or co-factor. Biochem Biophys Res Commun (2012) 0.87
Estradiol downregulation of the tumor suppressor gene BTG2 requires estrogen receptor-alpha and the REA corepressor. Int J Cancer (2009) 0.84
53BP1 suppresses tumor growth and promotes susceptibility to apoptosis of ovarian cancer cells through modulation of the Akt pathway. Oncol Rep (2012) 0.82
Potential risk factors for cutaneous squamous cell carcinoma include oral contraceptives: results of a nested case-control study. Int J Environ Res Public Health (2010) 0.82
Orphan nuclear receptor PNR/NR2E3 stimulates p53 functions by enhancing p53 acetylation. Mol Cell Biol (2011) 0.82
The p53-estrogen receptor loop in cancer. Curr Mol Med (2013) 0.82
MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy. Mol Med (2012) 0.81
Glucocorticoid receptor activation inhibits p53-induced apoptosis of MCF10Amyc cells via induction of protein kinase Cε. J Biol Chem (2012) 0.81
Activation of p53 transcriptional activity by SMRT: a histone deacetylase 3-independent function of a transcriptional corepressor. Mol Cell Biol (2014) 0.80
The role of p53 in cancer drug resistance and targeted chemotherapy. Oncotarget (2016) 0.79
Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway. Br J Cancer (2012) 0.79
The DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation. Cancer Biol Ther (2012) 0.78
Maintenance of S-nitrosothiol homeostasis plays an important role in growth suppression of estrogen receptor-positive breast tumors. Breast Cancer Res (2012) 0.77
p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis? PLoS One (2012) 0.77
Effects of the environmental mammary carcinogen 6-nitrochrysene on p53 and p21(Cip1) protein expression and cell cycle regulation in MCF-7 and MCF-10A cells. Chem Biol Interact (2007) 0.77
Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer. Oncotarget (2016) 0.77
Enhancing the Effects of Low Dose Doxorubicin Treatment by the Radiation in T47D and SKBR3 Breast Cancer Cells. J Breast Cancer (2013) 0.76
Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways. Ecotoxicology (2012) 0.76
The combined influence of oral contraceptives and human papillomavirus virus on cutaneous squamous cell carcinoma. Clin Med Insights Oncol (2011) 0.76
ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function. Oncotarget (2016) 0.76
Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication. Mitochondrion (2013) 0.75
Formal modeling and analysis of ER-α associated Biological Regulatory Network in breast cancer. PeerJ (2016) 0.75
Annexin/S100A Protein Family Regulation through p14ARF-p53 Activation: A Role in Cell Survival and Predicting Treatment Outcomes in Breast Cancer. PLoS One (2017) 0.75
Multiple breast cancer cell-lines derived from a single tumor differ in their molecular characteristics and tumorigenic potential. PLoS One (2013) 0.75
Estrogen Receptor-β Modulation of the ERα-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer. Horm Cancer (2017) 0.75
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res (2006) 5.90
Safety and efficacy of N-acetylcysteine in children with non-acetaminophen-induced acute liver failure. Liver Transpl (2008) 1.97
Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors. Cancer Biol Ther (2005) 1.64
One liver, three recipients: segment IV from split-liver procedures as a source of hepatocytes for cell transplantation. Transplantation (2004) 1.62
A novel cytoplasmic tail MXXXL motif mediates the internalization of prostate-specific membrane antigen. Mol Biol Cell (2003) 1.60
Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia. J Hepatol (2005) 1.44
Clinical trials of cancer therapies targeting prostate-specific membrane antigen. Rev Recent Clin Trials (2007) 1.43
Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis. Cancer Res (2007) 1.42
Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Mol Biol Cell (2004) 1.33
Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London. Cell Transplant (2012) 1.31
Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization. PLoS One (2012) 1.31
Upregulation of tissue inhibitor of metalloproteinases (TIMP)-2 promotes matrix metalloproteinase (MMP)-2 activation and cell invasion in a human glioblastoma cell line. Lab Invest (2004) 1.30
Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles. Biomaterials (2011) 1.30
Dishonorable discharge: the oncogenic roles of cleaved E-cadherin fragments. Cancer Res (2012) 1.22
Prostate-specific membrane antigen association with filamin A modulates its internalization and NAALADase activity. Cancer Res (2003) 1.22
Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma. Mol Biol Cell (2003) 1.22
Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells. Am J Physiol Gastrointest Liver Physiol (2006) 1.19
Hepatocyte transplantation for inherited factor VII deficiency. Transplantation (2004) 1.18
Regulation of estrogenic effects by beclin 1 in breast cancer cells. Cancer Res (2008) 1.14
Na,K-ATPase subunits as markers for epithelial-mesenchymal transition in cancer and fibrosis. Mol Cancer Ther (2010) 1.13
Analysis of the Na,K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays. Cancer (2003) 1.10
Cigarette smoke condensate-induced transformation of normal human breast epithelial cells in vitro. Oncogene (2004) 1.09
Na,K-ATPase inhibition alters tight junction structure and permeability in human retinal pigment epithelial cells. Am J Physiol Cell Physiol (2003) 1.09
Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo. BMC Cancer (2011) 1.07
Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation. Proc Natl Acad Sci U S A (2010) 1.07
Na,K-ATPase and epithelial tight junctions. Front Biosci (Landmark Ed) (2009) 1.07
Ligation of HLA class I molecules on endothelial cells induces phosphorylation of Src, paxillin, and focal adhesion kinase in an actin-dependent manner. J Immunol (2002) 1.07
Interactions of tight junctions with membrane channels and transporters. Biochim Biophys Acta (2007) 1.06
Role of Na-K-ATPase in the assembly of tight junctions. Am J Physiol Renal Physiol (2003) 1.06
Janus model of the Na,K-ATPase beta-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization. J Mol Biol (2006) 1.05
Levetiracetam enhances p53-mediated MGMT inhibition and sensitizes glioblastoma cells to temozolomide. Neuro Oncol (2010) 1.04
Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2. Gastroenterology (2006) 1.03
Biological impediments to monoclonal antibody-based cancer immunotherapy. Mol Cancer Ther (2004) 1.02
Multiple functions of Na,K-ATPase in epithelial cells. Semin Nephrol (2005) 1.00
HPAF-II, a cell culture model to study pancreatic epithelial cell structure and function. Pancreas (2004) 0.99
Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor. Exp Cell Res (2011) 0.98
Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias. Blood (2010) 0.98
alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling. Mol Cancer Ther (2008) 0.97
Na,K-adenosine triphosphatase alpha1-subunit predicts survival of renal clear cell carcinoma. J Urol (2007) 0.97
Disruption of estrogen receptor alpha-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy. Breast Cancer Res Treat (2008) 0.96
Estrogen-mediated downregulation of CD24 in breast cancer cells. Int J Cancer (2008) 0.95
N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy. Mol Cancer Ther (2005) 0.94
Na,K-ATPase beta1-subunit increases the translation efficiency of the alpha1-subunit in MSV-MDCK cells. Mol Biol Cell (2004) 0.93
Immune and viral profile from tolerance to hepatitis B surface antigen clearance: a longitudinal study of vertically hepatitis B virus-infected children on combined therapy. J Virol (2010) 0.93
Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine. Mol Pharm (2012) 0.91
Protein expression based multimarker analysis of breast cancer samples. BMC Cancer (2011) 0.88
Estrogen-mediated upregulation of Noxa is associated with cell cycle progression in estrogen receptor-positive breast cancer cells. PLoS One (2011) 0.88
Prostate-specific membrane antigen associates with anaphase-promoting complex and induces chromosomal instability. Mol Cancer Ther (2008) 0.88
Long-term outcome and management of hepatopulmonary syndrome in children. Pediatr Transplant (2009) 0.86
Pediatric liver transplantation for metabolic liver disease: experience at King's College Hospital. Transplantation (2009) 0.86
Stabilization of p53 and transactivation of its target genes in response to replication blockade. Oncogene (2002) 0.86
Na,K-ATPase in the regulation of epithelial cell structure. Ann N Y Acad Sci (2003) 0.86
Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit. J Mol Cell Cardiol (2009) 0.85
Association of prostate-specific membrane antigen with caveolin-1 and its caveolae-dependent internalization in microvascular endothelial cells: implications for targeting to tumor vasculature. Microvasc Res (2006) 0.85
Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix. Int J Oncol (2007) 0.85
Neonatal liver failure: aetiologies and management--state of the art. Eur J Pediatr (2010) 0.85
Polarity of prostate specific membrane antigen, prostate stem cell antigen, and prostate specific antigen in prostate tissue and in a cultured epithelial cell line. Prostate (2003) 0.85
Effect of denture cleansers on surface hardness of resilient denture liners at various time intervals- an in vitro study. J Adv Prosthodont (2013) 0.84
Oral buccoadhesive films of ondansetron: Development and evaluation. Int J Pharm Investig (2013) 0.83
Na,K-ATPase β-subunit cis homo-oligomerization is necessary for epithelial lumen formation in mammalian cells. J Cell Sci (2012) 0.82
MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy. Mol Med (2012) 0.81
Liver failure in a neonate with congenital adrenal hyporesponsiveness. Eur J Pediatr (2003) 0.81
Expression of Na,K-ATPase-beta(1) subunit increases uptake and sensitizes carcinoma cells to oxaliplatin. Cancer Chemother Pharmacol (2009) 0.81
Sensitization of Candida albicans biofilms to various antifungal drugs by cyclosporine A. Ann Clin Microbiol Antimicrob (2012) 0.81
Expression of Na,K-ATPase beta-subunit in transformed MDCK cells increases the translation of the Na,K-ATPase alpha-subunit. Ann N Y Acad Sci (2003) 0.81
Enhanced sensitivity of colon tumour cells to natural killer cell cytotoxicity after mild thermal stress is regulated through HSF1-mediated expression of MICA. Int J Hyperthermia (2013) 0.80
Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer. Am J Physiol Lung Cell Mol Physiol (2012) 0.79
Differing effects of microtubule depolymerizing and stabilizing chemotherapeutic agents on t-SNARE-mediated apical targeting of prostate-specific membrane antigen. Mol Cancer Ther (2006) 0.79
Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells. Mol Cancer Ther (2013) 0.79
Interaction of prostate specific membrane antigen with clathrin and the adaptor protein complex-2. Int J Oncol (2007) 0.78
MGMT inhibition suppresses survivin expression in pancreatic cancer. Pancreas (2015) 0.78
In vitro effects of sera from children with acute liver failure on metabolic and synthetic activity of cryopreserved human hepatocytes. J Pediatr Gastroenterol Nutr (2009) 0.78
Baseline evaluation of serum markers of inflammation and their utility in clinical practice in paediatric liver transplant recipients. Clin Res Hepatol Gastroenterol (2012) 0.77
Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma. Mol Cancer Ther (2014) 0.75
Anti-Candida properties of asaronaldehyde of Acorus gramineus rhizome and three structural isomers. Chin Med (2013) 0.75
Putting the brakes on angiogenesis through a novel VEGF-KLH (kinoid) vaccine. Expert Rev Vaccines (2007) 0.75
Microstomia in a maxillectomy patient: A prosthetic challenge. Contemp Clin Dent (2011) 0.75
Epidemiology and clinical features of childhood chronic hepatitis B infection diagnosed in England. Pediatr Infect Dis J (2014) 0.75
Hepatic abscess: presentation in a previously healthy teenager. Arch Dis Child (2012) 0.75
Health-Related Quality of Life in Adolescent Patients with Hepatitis C Genotype 1 Treated with Sofosbuvir and Ledipasvir. J Pediatr Gastroenterol Nutr (2017) 0.75