Published in J Exp Med on February 13, 2006
Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B. J Clin Invest (2013) 2.04
Hepatocyte entry leads to degradation of autoreactive CD8 T cells. Proc Natl Acad Sci U S A (2011) 1.89
Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity. PLoS Biol (2009) 1.60
Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo. World J Gastroenterol (2006) 1.39
Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death. Gastroenterology (2008) 1.11
Immune tolerance in liver disease. Hepatology (2014) 1.05
Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria. PLoS One (2009) 1.04
Memory CD8 T cells specific for plasmodia liver-stage antigens maintain protracted protection against malaria. Front Immunol (2012) 0.94
T-cell migration: a naive paradigm? Immunology (2007) 0.90
Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice. Hepatology (2011) 0.89
Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses. Proc Natl Acad Sci U S A (2014) 0.89
Malaria and the liver: immunological hide-and-seek or subversion of immunity from within? Front Microbiol (2015) 0.88
Role of interleukin-21 in HBV infection: friend or foe? Cell Mol Immunol (2014) 0.87
Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system. PLoS One (2009) 0.86
Induced tolerance to rat liver allografts involves the apoptosis of intragraft T cells and the generation of CD4(+)CD25(+)FoxP3(+) T regulatory cells. Liver Transpl (2010) 0.83
Expression of hepatitis B virus x protein in hepatocytes suppresses CD8 T cell activity. Immune Netw (2010) 0.80
APC licensing and CD4+T cell help in liver-stage malaria. Front Microbiol (2014) 0.80
Rejection triggers liver transplant tolerance: Involvement of mesenchyme-mediated immune control mechanisms in mice. Hepatology (2015) 0.78
Characterizing the lymphopoietic kinetics and features of hematopoietic progenitors contained in the adult murine liver in vivo. PLoS One (2013) 0.76
Liver transplantation in the mouse: Insights into liver immunobiology, tissue injury, and allograft tolerance. Liver Transpl (2016) 0.76
The CD8 T-cell response during tolerance induction in liver transplantation. Clin Transl Immunology (2016) 0.75
Systemic IL-12 administration alters hepatic dendritic cell stimulation capabilities. PLoS One (2012) 0.75
Killer T cells find meaningful encounters through iMATEs. Nat Immunol (2013) 0.75
Liver macrophages in healthy and diseased liver. Pflugers Arch (2017) 0.75
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol (2001) 12.00
Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol (2005) 9.00
Origin of regulatory T cells with known specificity for antigen. Nat Immunol (2002) 7.49
Differential T cell costimulatory requirements in CD28-deficient mice. Science (1993) 6.93
Murine liver allograft transplantation: tolerance and donor cell chimerism. Hepatology (1994) 4.32
Hepatic T cells and liver tolerance. Nat Rev Immunol (2003) 3.51
Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance. Nat Med (2000) 3.26
Antigen presentation to naive CD4 T cells in the lymph node. Nat Immunol (2003) 3.03
Local control of the immune response in the liver. Immunol Rev (2000) 3.01
Selective retention of activated CD8+ T cells by the normal liver. J Immunol (1999) 2.23
CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity (1996) 2.09
Neighborhood politics: the immunoregulatory function of organ-resident liver endothelial cells. Trends Immunol (2001) 1.93
Orthotopic liver transplantation in the mouse. Transplantation (1991) 1.82
Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction. J Immunol (1997) 1.81
Thymic selection revisited: how essential is it? Immunol Rev (2003) 1.71
Vascular adhesion molecule-1 and intercellular adhesion molecule-1 expression on rat liver cells after lipopolysaccharide administration in vivo. Hepatology (1995) 1.69
Weaning of immunosuppression in liver transplant recipients. Transplantation (1997) 1.57
Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells. Gastroenterology (1999) 1.54
The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity. J Clin Invest (2004) 1.53
Split tolerance induced by orthotopic liver transplantation in mice. Transplantation (1994) 1.52
T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus. Proc Natl Acad Sci U S A (1994) 1.48
Antigen-specific primary activation of CD8+ T cells within the liver. J Immunol (2001) 1.47
Hepatocytes induce functional activation of naive CD8+ T lymphocytes but fail to promote survival. Eur J Immunol (1998) 1.47
Liver sinusoidal endothelial cells are insufficient to activate T cells. J Immunol (2004) 1.39
Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells. Gastroenterology (1996) 1.32
Impact of hepatic rearterialization on reperfusion injury and outcome after mouse liver transplantation. Transplantation (2003) 1.31
The effect of mutations in the MHC class I peptide binding groove on the cytotoxic T lymphocyte recognition of the Kb-restricted ovalbumin determinant. Eur J Immunol (1990) 1.30
Hepatitis C virus infection: when silence is deception. Trends Immunol (2003) 1.29
Passive and active mechanisms trap activated CD8+ T cells in the liver. J Immunol (2004) 1.27
Intestinal venous drainage through the liver is a prerequisite for oral tolerance induction. J Pediatr Surg (1994) 1.25
Dendritic cells and immune regulation in the liver. Gut (2003) 1.19
Antigen presentation by liver cells controls intrahepatic T cell trapping, whereas bone marrow-derived cells preferentially promote intrahepatic T cell apoptosis. J Immunol (2001) 1.19
Naive CD8+ T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells. J Immunol (2000) 1.17
Role of primary intrahepatic T-cell activation in the 'liver tolerance effect'. Immunol Cell Biol (2002) 1.16
Organ graft tolerance: the liver effect. Lancet (1994) 1.14
Aire: an update. Curr Opin Immunol (2004) 1.12
Oral tolerance: overview and historical perspectives. Ann N Y Acad Sci (2004) 1.11
Chimerism and tolerance in transplantation. Proc Natl Acad Sci U S A (2004) 1.07
Death by neglect as a deletional mechanism of peripheral tolerance. Int Immunol (1999) 1.03
Immunological tolerance--the liver effect. Immunol Rev (2000) 0.98
Understanding the pathogenesis of autoimmune hepatitis. Am J Gastroenterol (2001) 0.91
Spontaneous acceptance of liver allografts in the rat. Analysis of the immune response. Transplantation (1994) 0.89
Passenger leukocytes and microchimerism: what role in tolerance induction? Transplantation (2003) 0.88
Development of immunity to malaria may not be an entirely active process. Parasite Immunol (1995) 0.81
Microchimerism after liver transplantation: absence of rejection without abrogation of anti-donor cytotoxic T-lymphocyte-mediated alloreactivity. Liver Transpl (2005) 0.81
Chimerism after whole organ transplantation: its relationship to graft rejection and tolerance induction. Curr Opin Nephrol Hypertens (1994) 0.79
A role for persisting antigen, antigen presentation, and ICAM-1 in increased renal graft survival after oral or portal vein donor-specific immunization. Transplantation (1998) 0.79
The role of T suppressor cells in the maintenance of spontaneously accepted orthotopic rat liver allografts. Transplantation (1992) 0.78
Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages. Blood (2007) 2.37
Passive and active mechanisms trap activated CD8+ T cells in the liver. J Immunol (2004) 1.27
Immunomodulatory effects of the liver: deletion of activated CD4+ effector cells and suppression of IFN-gamma-producing cells after intravenous protein immunization. J Immunol (2002) 1.10
TLR-4 regulates CD8+ T cell trapping in the liver. J Immunol (2005) 0.89
HCV core and NS3 proteins manipulate human blood-derived dendritic cell development and promote Th 17 differentiation. Int Immunol (2011) 0.88
Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes. Hepatology (2002) 0.88
Indirect action of tumor necrosis factor-alpha in liver injury during the CD8+ T cell response to an adeno-associated virus vector in mice. Hepatology (2009) 0.84
TLRs in Hepatic Cellular Crosstalk. Gastroenterol Res Pract (2010) 0.82
Synergy between TLR3 and IL-18 promotes IFN-γ dependent TRAIL expression in human liver NK cells. Cell Immunol (2011) 0.81
Toll-like receptor signaling in liver diseases. Gastroenterol Res Pract (2011) 0.77
Dysfunctional memory CD8+ T cells after priming in the absence of the cell cycle regulator E2F4. Cell Immunol (2009) 0.77
A microsurgical approach to hepatic and extrahepatic antigen presentation and its effects on the migration pattern of activated CD8(+) T cells. Microsurgery (2007) 0.75