Memory CD8 T cells specific for plasmodia liver-stage antigens maintain protracted protection against malaria.

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Published in Front Immunol on December 10, 2012

Authors

Urszula Krzych1, Sarat Dalai, Stasya Zarling, Alexander Pichugin

Author Affiliations

1: Department of Cellular Immunology, Branch of Military Malaria Vaccine Development, Walter Reed Army Institute of Research Silver Spring, MD, USA.

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature (1999) 34.47

Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat Immunol (2003) 15.51

Tolerance, danger, and the extended family. Annu Rev Immunol (1994) 14.94

Immunological memory and protective immunity: understanding their relation. Science (1996) 10.02

Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol (2002) 9.45

Common west African HLA antigens are associated with protection from severe malaria. Nature (1991) 9.43

Cytotoxic T-cell memory without antigen. Nature (1994) 6.55

Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22

Persistence of memory CD8 T cells in MHC class I-deficient mice. Science (1999) 6.20

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity (2002) 6.10

Protective immunity produced by the injection of x-irradiated sporozoites of plasmodium berghei. Nature (1967) 6.08

Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites. Nature (1988) 5.99

Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol (2003) 5.90

Immunity to malaria: more questions than answers. Nat Immunol (2008) 5.71

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J Infect Dis (2002) 5.43

Programmed contraction of CD8(+) T cells after infection. Nat Immunol (2002) 5.16

CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites. Proc Natl Acad Sci U S A (1988) 4.67

Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell (2002) 4.52

Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants. N Engl J Med (2008) 4.35

Immunization of man against sporozite-induced falciparum malaria. Am J Med Sci (1973) 4.18

T cell memory. Annu Rev Immunol (2001) 3.70

Activated antigen-specific CD8+ T cells persist in the lungs following recovery from respiratory virus infections. J Immunol (2001) 3.68

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus. Proc Natl Acad Sci U S A (2004) 3.61

Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity (2001) 3.45

Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon. Science (1986) 3.33

On immunological memory. Annu Rev Immunol (1996) 3.21

Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med (2002) 3.20

T cell memory is short-lived in the absence of antigen. J Exp Med (1991) 3.16

Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci U S A (2005) 3.06

A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites. J Biol Chem (2003) 2.84

The silent path to thousands of merozoites: the Plasmodium liver stage. Nat Rev Microbiol (2006) 2.83

CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes. Nat Med (2007) 2.79

Residual antigen presentation after influenza virus infection affects CD8 T cell activation and migration. Immunity (2006) 2.78

IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation. J Immunol (2001) 2.65

Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria. Proc Natl Acad Sci U S A (2008) 2.62

Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J Exp Med (2005) 2.59

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. Cell Microbiol (2008) 2.49

Functional and ontogenetic analysis of murine CD45Rhi and CD45Rlo CD4+ T cells. J Immunol (1990) 2.41

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proc Natl Acad Sci U S A (2003) 2.38

IL-15 and IL-2: a matter of life and death for T cells in vivo. Nat Med (2001) 2.29

Selective retention of activated CD8+ T cells by the normal liver. J Immunol (1999) 2.23

Malaria sporozoites actively enter and pass through rat Kupffer cells prior to hepatocyte invasion. Hepatology (2001) 2.06

Characterization of Plasmodium falciparum sporozoite surface protein 2. Proc Natl Acad Sci U S A (1992) 2.00

Swift development of protective effector functions in naive CD8(+) T cells against malaria liver stages. J Exp Med (2001) 1.99

Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. J Infect Dis (2007) 1.99

Secondary replicative function of CD8+ T cells that had developed an effector phenotype. Science (2009) 1.96

IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model. J Immunol (1999) 1.92

Inhibitory activity of interferons and interleukin 1 on the development of Plasmodium falciparum in human hepatocyte cultures. J Immunol (1987) 1.89

Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated Plasmodium berghei infected mosquitoes: involvement of interferon gamma and CD8+ T cells. J Exp Med (1994) 1.83

Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. J Infect Dis (2007) 1.79

Interleukin 12 induction of interferon gamma-dependent protection against malaria. Proc Natl Acad Sci U S A (1994) 1.77

Cutting edge: latecomer CD8 T cells are imprinted with a unique differentiation program. J Immunol (2006) 1.73

Plasmodium falciparum liver stage antigen-1 is well conserved and contains potent B and T cell determinants. J Immunol (1994) 1.72

Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. J Immunol (2001) 1.66

T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stages. Annu Rev Immunol (1993) 1.64

Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell Host Microbe (2011) 1.61

Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. Proc Natl Acad Sci U S A (1991) 1.61

Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells. J Immunol (2003) 1.60

The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules. J Exp Med (1992) 1.56

Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites. Proc Natl Acad Sci U S A (1995) 1.55

Development and regulation of cell-mediated immune responses to the blood stages of malaria: implications for vaccine research. Annu Rev Immunol (2005) 1.53

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection. J Exp Med (2010) 1.52

Longevity and composition of cellular immune responses following experimental Plasmodium falciparum malaria infection in humans. PLoS Pathog (2011) 1.51

Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells. Am J Pathol (2007) 1.51

Cutting edge: dendritic cells copulsed with microbial and helminth antigens undergo modified maturation, segregate the antigens to distinct intracellular compartments, and concurrently induce microbe-specific Th1 and helminth-specific Th2 responses. J Immunol (2004) 1.49

Early signals during CD8 T cell priming regulate the generation of central memory cells. J Immunol (2010) 1.49

Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes. EMBO J (1995) 1.49

Antigen-specific primary activation of CD8+ T cells within the liver. J Immunol (2001) 1.47

Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med (2009) 1.42

Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites. PLoS Pathog (2010) 1.39

The induction and persistence of T cell IFN-gamma responses after vaccination or natural exposure is suppressed by Plasmodium falciparum. J Immunol (2007) 1.38

Humoral immune responses in volunteers immunized with irradiated Plasmodium falciparum sporozoites. Am J Trop Med Hyg (1993) 1.34

MHC class I-dependent presentation of exoerythrocytic antigens to CD8+ T lymphocytes is required for protective immunity against Plasmodium berghei. J Immunol (1996) 1.29

Genetically attenuated parasite vaccines induce contact-dependent CD8+ T cell killing of Plasmodium yoelii liver stage-infected hepatocytes. J Immunol (2009) 1.27

Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo. PLoS Pathog (2011) 1.27

Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells. J Immunol (2011) 1.26

Early interactions between blood-stage plasmodium parasites and the immune system. Curr Top Microbiol Immunol (2005) 1.26

Development of antimalaria immunity in mice lacking IFN-gamma receptor. J Immunol (1995) 1.25

Complete differentiation of CD8+ T cells activated locally within the transplanted liver. J Exp Med (2006) 1.25

Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming. Nat Med (1999) 1.24

Irradiated sporozoite vaccine induces HLA-B8-restricted cytotoxic T lymphocyte responses against two overlapping epitopes of the Plasmodium falciparum sporozoite surface protein 2. J Exp Med (1995) 1.23

Liver antigen-presenting cells. J Hepatol (2010) 1.22

T lymphocytes from volunteers immunized with irradiated Plasmodium falciparum sporozoites recognize liver and blood stage malaria antigens. J Immunol (1995) 1.19

Plasmodium berghei-infected primary hepatocytes process and present the circumsporozoite protein to specific CD8+ T cells in vitro. J Immunol (2007) 1.16

Co-localization of inducible-nitric oxide synthase and Plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoites. J Immunol (1995) 1.12

Short-term antigen presentation and single clonal burst limit the magnitude of the CD8(+) T cell responses to malaria liver stages. Proc Natl Acad Sci U S A (2002) 1.10

IL-15 transpresentation augments CD8+ T cell activation and is required for optimal recall responses by central memory CD8+ T cells. J Immunol (2008) 1.10

Plasmodium falciparum sporozoite invasion is inhibited by naturally acquired or experimentally induced polyclonal antibodies to the STARP antigen. Eur J Immunol (1997) 1.10

The dissection of CD8 T cells during liver-stage infection. Curr Top Microbiol Immunol (2005) 1.08

Studies on anti-leishmania activity of immune rabbit serum. J Parasitol (1970) 1.08

Cutting edge: Asymmetric memory T cell division in response to rechallenge. J Immunol (2012) 1.07

Memory phenotype CD8(+) T cells persist in livers of mice protected against malaria by immunization with attenuated Plasmodium berghei sporozoites. Eur J Immunol (1999) 1.05

Long term protection after immunization with P. berghei sporozoites correlates with sustained IFNγ responses of hepatic CD8+ memory T cells. PLoS One (2012) 1.04

Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria. PLoS One (2009) 1.04

SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages. Mol Microbiol (2010) 1.04

Conserved repetitive epitope recognized by CD4+ clones from a malaria-immunized volunteer. Science (1989) 0.98

Gamma(c) deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors. Proc Natl Acad Sci U S A (2010) 0.95

Plasmodium-host interactions directly influence the threshold of memory CD8 T cells required for protective immunity. J Immunol (2011) 0.95

The role of intrahepatic lymphocytes in mediating protective immunity induced by attenuated Plasmodium berghei sporozoites. Immunol Rev (2000) 0.95

The immune status of Kupffer cells profoundly influences their responses to infectious Plasmodium berghei sporozoites. Eur J Immunol (2005) 0.92