Published in Cell Signal on February 23, 2006
TRPA1 is a major oxidant sensor in murine airway sensory neurons. J Clin Invest (2008) 2.55
A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel. Cell (2013) 2.25
Regulation of NF-κB by deubiquitinases. Immunol Rev (2012) 1.78
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells. Proc Natl Acad Sci U S A (2009) 1.52
TRPA1: A gatekeeper for inflammation. Annu Rev Physiol (2012) 1.36
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators. Pflugers Arch (2008) 1.31
Transient receptor potential (TRP) channels: a clinical perspective. Br J Pharmacol (2014) 1.25
Role of the ubiquitin system in regulating ion transport. Pflugers Arch (2010) 1.12
Update of cylindromatosis gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling. Hum Mutat (2009) 1.09
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours. Oncogene (2011) 1.06
Transient receptor potential (TRP) channels in the airway: role in airway disease. Br J Pharmacol (2014) 1.05
TRP channels and analgesia. Life Sci (2012) 0.99
ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1. Curr Neuropharmacol (2008) 0.93
Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects. Br J Pharmacol (2012) 0.90
Species-specific temperature sensitivity of TRPA1. Temperature (Austin) (2015) 0.84
Trafficking of ThermoTRP Channels. Membranes (Basel) (2014) 0.83
The role of TRPA1 in visceral inflammation and pain. Channels (Austin) (2011) 0.82
Targeting TRP channels for chronic cough: from bench to bedside. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.80
A global profile of gene promoter methylation in treatment-naïve urothelial cancer. Epigenetics (2014) 0.80
Pacific island 'Awa (Kava) extracts, but not isolated kavalactones, promote proinflammatory responses in model mast cells. Phytother Res (2012) 0.79
USP18 Sensitivity of Peptide Transporters PEPT1 and PEPT2. PLoS One (2015) 0.76
Involvement of the gut chemosensory system in the regulation of colonic anion secretion. Biomed Res Int (2015) 0.75
Transient Receptor Potential (TRP) channels in T cells. Semin Immunopathol (2015) 0.75
N-terminal tetrapeptide T/SPLH motifs contribute to multimodal activation of human TRPA1 channel. Sci Rep (2016) 0.75
Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation. Sci Rep (2017) 0.75
Differential regulation of calcium signalling pathways by components of Piper methysticum ('Awa). Phytother Res (2015) 0.75
Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nat Cell Biol (2006) 6.31
CRACM1 multimers form the ion-selective pore of the CRAC channel. Curr Biol (2006) 6.02
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell (2003) 4.15
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization. Cell (2002) 3.13
CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. Curr Biol (2007) 3.12
TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. J Gen Physiol (2003) 2.86
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat Med (2008) 2.77
Immunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetes. Diabetes (2008) 2.25
Dissociation of the store-operated calcium current I(CRAC) and the Mg-nucleotide-regulated metal ion current MagNuM. J Physiol (2002) 2.16
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. Mol Cell (2005) 2.15
Immunomodulatory function of bone marrow-derived mesenchymal stem cells in experimental autoimmune type 1 diabetes. J Immunol (2009) 2.15
2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. J Physiol (2008) 2.11
TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i. Proc Natl Acad Sci U S A (2003) 2.01
Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes. FASEB J (2006) 1.81
STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. FASEB J (2007) 1.77
TRPM7 channel is regulated by magnesium nucleotides via its kinase domain. J Gen Physiol (2006) 1.76
Differential roles of CB1 and CB2 cannabinoid receptors in mast cells. J Immunol (2003) 1.75
TRPM5 regulates glucose-stimulated insulin secretion. Pflugers Arch (2010) 1.74
TRPM4 regulates calcium oscillations after T cell activation. Science (2004) 1.74
Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes. J Exp Med (2002) 1.73
TRPM2 functions as a lysosomal Ca2+-release channel in beta cells. Sci Signal (2009) 1.71
The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys (2010) 1.69
TRPM7 is essential for Mg(2+) homeostasis in mammals. Nat Commun (2010) 1.60
Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain. Proc Natl Acad Sci U S A (2004) 1.46
SLC41A1 is a novel mammalian Mg2+ carrier. J Biol Chem (2008) 1.37
Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca(2+) entry via STIM proteins. Cell Calcium (2009) 1.28
Regulation of TRPM2 by extra- and intracellular calcium. J Gen Physiol (2007) 1.28
TRPM4 controls insulin secretion in pancreatic beta-cells. Cell Calcium (2006) 1.27
A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells. J Exp Med (2004) 1.25
A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. J Gen Physiol (2010) 1.24
Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils. Cell Calcium (2008) 1.22
The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification. J Physiol (2010) 1.18
Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels. J Biol Chem (2011) 1.15
Human HTm4 is a hematopoietic cell cycle regulator. J Clin Invest (2002) 1.15
Functional promoter polymorphism in the TBX21 gene associated with aspirin-induced asthma. Hum Genet (2005) 1.14
Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer. Nat Commun (2013) 1.13
A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity. Mol Pharmacol (2006) 1.13
Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes. PLoS One (2008) 1.12
Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity. Biochem J (2003) 1.12
Cell cycle-dependent regulation of store-operated I(CRAC) and Mg2+-nucleotide-regulated MagNuM (TRPM7) currents. Cell Calcium (2006) 1.12
A randomized, double-blind comparison study of EMLA and ELA-Max for topical anesthesia in children undergoing intravenous insertion. Paediatr Anaesth (2004) 1.08
ELL facilitates RNA polymerase II pause site entry and release. Nat Commun (2012) 1.07
Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release. FASEB J (2011) 1.04
Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma. J Allergy Clin Immunol (2002) 1.03
Including culturally diverse samples in health research: a case study of an urban trial of social support. Ethn Health (2003) 1.03
Formation of a physiological complex between TRPV2 and RGA protein promotes cell surface expression of TRPV2. J Cell Biochem (2005) 1.03
Activation of store-operated I(CRAC) by hydrogen peroxide. Cell Calcium (2010) 1.02
Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms. Pediatr Res (2004) 1.02
The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels. J Biol Chem (2014) 0.99
Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers. BMC Cancer (2013) 0.97
Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A. J Immunol (2008) 0.96
RGA protein associates with a TRPV ion channel during biosynthesis and trafficking. J Cell Biochem (2004) 0.96
Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS One (2012) 0.94
Transplant tourism outcome: a single center experience. Transplantation (2010) 0.94
Effluxing ABC transporters in human corneal epithelium. J Pharm Sci (2010) 0.93
TRPM7 channel is sensitive to osmotic gradients in human kidney cells. J Physiol (2007) 0.93
Genetic diagnosis in consanguineous families with kidney disease by homozygosity mapping coupled with whole-exome sequencing. Am J Kidney Dis (2011) 0.91
Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors. J Biomol Screen (2010) 0.91
Characterization of the expression of HTm4 (MS4A3), a cell cycle regulator, in human peripheral blood cells and normal and malignant tissues. J Cell Mol Med (2011) 0.90
Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2. J Biol Chem (2005) 0.89
Identification of granulocyte subtype-selective receptors and ion channels by using a high-density oligonucleotide probe array. J Allergy Clin Immunol (2004) 0.89
DUSP5 and DUSP6 modulate corneal epithelial cell proliferation. Mol Vis (2010) 0.88
TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells. Cell Calcium (2013) 0.88
Molecular profiling of conjunctival epithelial side-population stem cells: atypical cell surface markers and sources of a slow-cycling phenotype. Invest Ophthalmol Vis Sci (2009) 0.88
Differential gene expression in the pig limbal side population: implications for stem cell cycling, replication, and survival. Invest Ophthalmol Vis Sci (2009) 0.86
Store-operated calcium entry: a tough nut to CRAC. Sci STKE (2004) 0.86
Beyond apoptosis: the mechanism and function of phosphatidylserine asymmetry in the membrane of activating mast cells. Bioarchitecture (2014) 0.86
TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice. J Inflamm (Lond) (2013) 0.85
Effects of chronic bhang (cannabis) administration on the reproductive system of male mice. Birth Defects Res B Dev Reprod Toxicol (2011) 0.84
Assessment of acute and chronic pain symptoms in children with cystic fibrosis. Pediatr Pulmonol (2005) 0.84
Discovery of serum protein biomarkers for prostate cancer progression by proteomic analysis. Cancer Genomics Proteomics (2010) 0.84
Lipopolysaccharide-induced down-regulation of Ca2+ release-activated Ca2+ currents (I CRAC) but not Ca2+-activated TRPM4-like currents (I CAN) in cultured mouse microglial cells. J Physiol (2007) 0.84
TRPM7 is regulated by halides through its kinase domain. Cell Mol Life Sci (2013) 0.83
Aryl hydrocarbon receptor ligand effects in RBL2H3 cells. J Immunotoxicol (2012) 0.83
Exposure to tobacco-derived materials induces overproduction of secreted proteinases in mast cells. Toxicol Appl Pharmacol (2005) 0.82
Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells. Biochem J (2005) 0.82
Evaluating parent support initiatives: lessons from two case studies. Health Soc Care Community (1998) 0.81
Fcepsilon RI control of Ras via inositol (1,4,5) trisphosphate 3-kinase and inositol tetrakisphosphate. Cell Signal (2005) 0.81
IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). Cell Calcium (2009) 0.81
MRSA screening on a paediatric intensive care unit. Arch Dis Child (2010) 0.81
Cell cycle disruption and apoptotic activity of 3-aminothiazolo[3,2-a]benzimidazole-2-carbonitrile and its homologues. Eur J Med Chem (2010) 0.81
Insulin-containing lipogenic stimuli suppress mast cell degranulation potential and up-regulate lipid body biogenesis and eicosanoid secretion in a PPARγ-independent manner. J Leukoc Biol (2012) 0.80
Immunoactive effects of cannabinoids: considerations for the therapeutic use of cannabinoid receptor agonists and antagonists. Int Immunopharmacol (2010) 0.80
Pacific island 'Awa (Kava) extracts, but not isolated kavalactones, promote proinflammatory responses in model mast cells. Phytother Res (2012) 0.79
The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice. J Mol Histol (2005) 0.79
Demographic and clinical characteristics of adolescents in Hawaii with obsessive-compulsive disorder. Arch Pediatr Adolesc Med (2003) 0.78
D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: biological activity and pH-dependent conformational properties. Biochem Biophys Res Commun (2004) 0.78
A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours. Cancer Chemother Pharmacol (2013) 0.77
Correction: High Throughput Measurement of γH2AX DSB Repair Kinetics in a Healthy Human Population. PLoS One (2015) 0.76
Comparative analysis of lipotoxicity induced by endocrine, pharmacological, and innate immune stimuli in rat basophilic leukemia cells. J Immunotoxicol (2014) 0.76