Satish K Nair

Author PubWeight™ 57.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep 2013 5.38
2 Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis. Science 2006 3.29
3 Molecular basis for the recognition of structurally distinct autoinducer mimics by the Pseudomonas aeruginosa LasR quorum-sensing signaling receptor. Chem Biol 2009 1.88
4 Lantibiotics from Geobacillus thermodenitrificans. Proc Natl Acad Sci U S A 2012 1.53
5 An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis. Nature 2009 1.51
6 Cutting edge: molecular structure of the IL-1R-associated kinase-4 death domain and its implications for TLR signaling. J Immunol 2005 1.45
7 In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis. Proc Natl Acad Sci U S A 2008 1.39
8 Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc Natl Acad Sci U S A 2012 1.38
9 Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst. J Am Chem Soc 2010 1.38
10 Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters. Structure 2007 1.25
11 Enzymatic basis of ribosomal peptide prenylation in cyanobacteria. J Am Chem Soc 2011 1.25
12 Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. Proc Natl Acad Sci U S A 2010 1.20
13 Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc Natl Acad Sci U S A 2012 1.17
14 Insights into the architecture of the replicative helicase from the structure of an archaeal MCM homolog. Structure 2009 1.12
15 Structures of cyanobactin maturation enzymes define a family of transamidating proteases. Chem Biol 2012 1.06
16 Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proc Natl Acad Sci U S A 2012 1.03
17 Cryo-electron microscopy reveals a novel DNA-binding site on the MCM helicase. EMBO J 2008 1.03
18 Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis. Proc Natl Acad Sci U S A 2013 1.03
19 Molecular basis for the selectivity and specificity of ligand recognition by the family 16 carbohydrate-binding modules from Thermoanaerobacterium polysaccharolyticum ManA. J Biol Chem 2007 1.02
20 Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa. Chem Biol 2008 1.01
21 Identification of hydrogen bonds to the Rieske cluster through the weakly coupled nitrogens detected by electron spin echo envelope modulation spectroscopy. J Biol Chem 2006 1.00
22 The crystal structure of human soluble CD14 reveals a bent solenoid with a hydrophobic amino-terminal pocket. J Immunol 2012 0.97
23 Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proc Natl Acad Sci U S A 2013 0.96
24 Biochemical and structural insights into xylan utilization by the thermophilic bacterium Caldanaerobius polysaccharolyticus. J Biol Chem 2012 0.95
25 Roles of small laccases from Streptomyces in lignin degradation. Biochemistry 2014 0.95
26 Modifications of protein environment of the [2Fe-2S] cluster of the bc1 complex: effects on the biophysical properties of the rieske iron-sulfur protein and on the kinetics of the complex. J Biol Chem 2009 0.95
27 Structural and mechanistic insights into C-P bond hydrolysis by phosphonoacetate hydrolase. Chem Biol 2011 0.95
28 Structure of a PL17 family alginate lyase demonstrates functional similarities among exotype depolymerases. J Biol Chem 2014 0.95
29 Structure and function of the c-myc DNA-unwinding element-binding protein DUE-B. J Biol Chem 2007 0.94
30 Structure, function and inhibition of the two- and three-domain 4Fe-4S IspG proteins. Proc Natl Acad Sci U S A 2012 0.91
31 A microfluidic approach for protein structure determination at room temperature via on-chip anomalous diffraction. Lab Chip 2013 0.89
32 Intracellular TLR signaling: a structural perspective on human disease. J Immunol 2006 0.89
33 Quorum sensing: how bacteria can coordinate activity and synchronize their response to external signals? Protein Sci 2012 0.86
34 Microcin C: biosynthesis and mechanisms of bacterial resistance. Future Microbiol 2012 0.85
35 Structures of the PelD cyclic diguanylate effector involved in pellicle formation in Pseudomonas aeruginosa PAO1. J Biol Chem 2012 0.85
36 Methanosarcina acetivorans flap endonuclease 1 activity is inhibited by a cognate single-stranded-DNA-binding protein. J Bacteriol 2006 0.83
37 Structural basis for microcin C7 inactivation by the MccE acetyltransferase. J Biol Chem 2011 0.82
38 Molecular analyses of an unusual translesion DNA polymerase from Methanosarcina acetivorans C2A. J Mol Biol 2010 0.82
39 Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration. Biochemistry 2012 0.82
40 Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase. Biochemistry 2011 0.80
41 Structure and engineering of L-arabinitol 4-dehydrogenase from Neurospora crassa. J Mol Biol 2010 0.80
42 Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis. Proteins 2011 0.80
43 Crystal structures of lipoglycopeptide antibiotic deacetylases: implications for the biosynthesis of A40926 and teicoplanin. Chem Biol 2008 0.80
44 Mutational insights into the roles of amino acid residues in ligand binding for two closely related family 16 carbohydrate binding modules. J Biol Chem 2010 0.80
45 A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase. J Am Chem Soc 2015 0.79
46 Structural and functional analyses of a glycoside hydrolase family 5 enzyme with an unexpected β-fucosidase activity. Biochemistry 2011 0.78
47 New N-acetyltransferase fold in the structure and mechanism of the phosphonate biosynthetic enzyme FrbF. J Biol Chem 2011 0.77
48 Substrate specificity of the lanthipeptide peptidase ElxP and the oxidoreductase ElxO. ACS Chem Biol 2014 0.77
49 Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor. Chem Commun (Camb) 2015 0.76
50 Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme. Biochemistry 2007 0.75
51 Metal ion-mediated reduction in surface entropy improves diffraction quality of crystals of the IRAK-4 death domain. J Biomol Tech 2006 0.75
52 Structure and function of a serine carboxypeptidase adapted for degradation of the protein synthesis antibiotic microcin C7. Proc Natl Acad Sci U S A 2012 0.75