Published in Virology on June 01, 1975
Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin. Proc Natl Acad Sci U S A (1979) 5.32
Endogenous ecotropic mouse type C viruses deficient in replication and production of XC plaques. J Virol (1976) 1.87
New mammalian transforming retrovirus: demonstration of a polyprotein gene product. J Virol (1983) 1.55
A new class of genetically transmitted retravirus isolated from Mus cervicolor. Proc Natl Acad Sci U S A (1976) 1.46
Molecular and biological characterization of the endogenous ecotropic provirus of BALB/c mice. J Virol (1985) 1.45
Isolation of the mouse mammary tumor virus sequences not transmitted as germinal provirus in the C3H and RIII mouse strains. J Virol (1977) 1.39
N-Tropic variants obtained after co-infection with N- and B-tropic murine leukemia viruses. J Virol (1976) 1.37
Evidence for an early evolutionary origin and locus polymorphism of mouse VL30 DNA sequences. J Virol (1982) 1.26
Type-specific antigenic determinants on the major external glycoprotein of high- and low-oncogenic murine mammary tumor viruses. J Virol (1977) 1.16
Generation of oncogenic mouse type C viruses: in vitro selection of carcinoma-inducing variants. Proc Natl Acad Sci U S A (1980) 1.09
Endogenous mink (Mustela vison) type C virus isolated from sarcoma virus-transformed mink cells. J Virol (1978) 1.08
Tumorigenic methylcholanthrene transformants of C3H/10T1/2 cells have a common nucleotide alteration in the c-Ki-ras gene. Proc Natl Acad Sci U S A (1989) 1.07
Generation of oncogenic type C viruses: rapidly leukemogenic viruses derived from C3H mouse cells in vivo and in vitro. Proc Natl Acad Sci U S A (1978) 1.06
Genome structure of mink cell focus-forming murine leukemia virus in epithelial mink lung cells transformed vitro by iododeoxyuridine-induced C3H/MuLV cells. J Virol (1983) 1.04
Carcinogen- and radiation-transformed C3H 10T1/2 cells contain RNAs homologous to the long terminal repeat sequence of a murine leukemia virus. Proc Natl Acad Sci U S A (1982) 1.04
Genetic control of natural immunity to ecotropic mouse leukemia viruses: production of endogenous immunogen. Infect Immun (1976) 0.89
Evolution and modes of transmission of RNA tumor viruses. Parke-Davis Award lecture. Am J Pathol (1975) 0.87
Systemic interleukin 12 displays anti-tumour activity in the mouse central nervous system. Br J Cancer (1998) 0.84
Monoclonal antibodies to Chlamydia trachomatis: antibody specificities and antigen characterization. J Immunol (1982) 8.61
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res (1973) 7.59
Raf-1 activates MAP kinase-kinase. Nature (1992) 7.05
Culture-independent diagnosis of Chlamydia trachomatis using monoclonal antibodies. N Engl J Med (1984) 6.08
Serological classification of Neisseria gonorrhoeae with monoclonal antibodies. Infect Immun (1982) 5.54
Serological classification of Neisseria gonorrhoeae with use of monoclonal antibodies to gonococcal outer membrane protein I. J Infect Dis (1984) 5.40
Protein kinase C alpha activates RAF-1 by direct phosphorylation. Nature (1993) 5.23
A proposed nomenclature for the virion proteins of oncogenic RNA viruses. Virology (1974) 5.01
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature (1993) 4.88
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell (1989) 4.86
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus. Proc Natl Acad Sci U S A (1983) 4.82
The isolation of hybrid cell lines producing monoclonal antibodies against the p15(E) protein of ecotropic murine leukemia viruses. Virology (1979) 4.59
Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Res (1973) 4.54
Active Ras induces heterodimerization of cRaf and BRaf. Cancer Res (2001) 4.20
Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell (1996) 4.04
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature (1991) 4.04
Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase. Genes Dev (1992) 3.46
Detection of avian and mammalian oncogenic RNA viruses (oncornaviruses) by immunofluorescence. Cancer Res (1972) 3.23
Monoclonal antibodies to cytomegalovirus: rapid identification of clinical isolates and preliminary use in diagnosis of cytomegalovirus pneumonia. Infect Immun (1982) 3.22
Identification of a human T lymphocyte surface protein associated with the E-rosette receptor. J Exp Med (1981) 3.06
Selective heat sensitivity of cancer cells. Biochemical and clinical studies. Cancer (1967) 3.04
Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade. Nat Cell Biol (2001) 2.93
Chromatographic separation and antigenic analysis of proteins of the oncornaviruses. II. Mammalian leukemia-sarcoma viruses. J Virol (1972) 2.84
Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins. Nature (1985) 2.82
Endothelial apoptosis in Braf-deficient mice. Nat Genet (1997) 2.77
Chemical carcinogenesis. Annu Rev Biochem (1975) 2.70
Identification of the major phosphorylation sites of the Raf-1 kinase. J Biol Chem (1993) 2.70
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus. Nature (1986) 2.64
Fluorinated pyrimidines. Prog Nucleic Acid Res Mol Biol (1965) 2.63
Monoclonal antibodies against murine leukemia viruses: identification of six antigenic determinants on the p 15(E) and gp70 envelope proteins. Virology (1979) 2.62
Monoclonal antibodies to herpes simplex viruses: use in antigenic typing and rapid diagnosis. J Infect Dis (1983) 2.60
The ins and outs of Raf kinases. Trends Biochem Sci (1994) 2.51
Typing of clinical herpes simplex virus isolates with mouse monoclonal antibodies to herpes simplex virus types 1 and 2: comparison with type-specific rabbit antisera and restriction endonuclease analysis of viral DNA. J Clin Microbiol (1983) 2.50
The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene. Nucleic Acids Res (1986) 2.50
Transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains. J Mol Biol (1973) 2.45
Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1. Mol Cell Biol (1997) 2.37
Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73. Mol Cell Biol (1992) 2.34
Oncogenicity of AKR endogenous leukemia viruses. J Virol (1978) 2.31
Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: activation of c-Jun N-terminal kinase in HeLa cells. Infect Immun (1999) 2.26
Group-specific viral antigens in the milk and tissues of mice naturally infected with mammary tumor virus or Gross leukemia virus. Virology (1968) 2.26
Mutational activation of c-raf-1 and definition of the minimal transforming sequence. Mol Cell Biol (1990) 2.24
In vitro transformation of rodent cells by K-region derivatives of polycyclic hydrocarbons. Proc Natl Acad Sci U S A (1971) 2.21
Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci U S A (1996) 2.21
Common properties of the oncogenic RNA viruses (oncornaviruses). Virology (1970) 2.20
Structure and biological activity of human homologs of the raf/mil oncogene. Mol Cell Biol (1985) 2.19
Monoclonal antibodies for diagnosis of infectious diseases in humans. Science (1983) 2.02
The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus. Nucleic Acids Res (1987) 1.98
Quantitative studies on the malignant transformation of mouse prostate cells by carcinogenic hydrocarbons in vitro. Int J Cancer (1969) 1.96
Antibody to leukemia virus: widespread occurrence in inbred mice. Science (1974) 1.91
Rescue of endogenous 30S retroviral sequences from mouse cells by baboon type C virus. J Virol (1978) 1.90
Mammary tumour virus specific nucleotide sequences in mouse DNA. Nat New Biol (1972) 1.87
Endogenous ecotropic mouse type C viruses deficient in replication and production of XC plaques. J Virol (1976) 1.87
Characterization of monoclonal antibodies to Treponema pallidum. J Immunol (1985) 1.83
Isotype-specific functions of Raf kinases. Exp Cell Res (1999) 1.79
Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes. Nature (1985) 1.77
Serological analysis of the deoxyribonucleic acid polymerase of avian oncornaviruses. II. Comparison of avian deoxyribonucleic acid polymerases. J Virol (1972) 1.75
Cell cycle targets of Ras/Raf signalling. Oncogene (1998) 1.75
Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase. Oncogene (1994) 1.74
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation. J Biol Chem (1994) 1.74
Oncornaviruses produced by murine leukemia cells in culture. Virology (1977) 1.73
Topological mapping of murine leukemia virus proteins by competition-binding assays with monoclonal antibodies. Virology (1980) 1.72
Nucleotide sequence of avian retroviral oncogene v-mil: homologue of murine retroviral oncogene v-raf. Nature (1984) 1.68
Expression of raf oncogenes activates the PEA1 transcription factor motif. Mol Cell Biol (1989) 1.66
The human homologs of the raf (mil) oncogene are located on human chromosomes 3 and 4. Science (1984) 1.66
Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells. Cancer Res (1976) 1.64
Detection of the myristylated gag-raf transforming protein with raf-specific antipeptide sera. Virology (1985) 1.64
Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. Mol Cell Biol (1989) 1.64
3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways. Mol Cell Biol (1996) 1.63
Mutagenicity to mammalian cells of epoxides and other derivatives of polycyclic hydrocarbons. Proc Natl Acad Sci U S A (1971) 1.61
Integration of transfected LTR sequences into the c-raf proto-oncogene: activation by promoter insertion. EMBO J (1985) 1.60
Viral proteins expressed on the surface of murine leukemia cells. J Virol (1977) 1.60
Cancer chemotherapy with purine and pyrimidine analogues. Annu Rev Pharmacol (1967) 1.59
p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells. Cancer Res (1999) 1.57
Primary structure of v-raf: relatedness to the src family of oncogenes. Science (1984) 1.56
Homologous cell-derived oncogenes in avian carcinoma virus MH2 and murine sarcoma virus 3611. Nature (1984) 1.56
New mammalian transforming retrovirus: demonstration of a polyprotein gene product. J Virol (1983) 1.55
Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product. EMBO J (1990) 1.55
Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells. J Virol (1977) 1.54
Fluorinated pyrimidines and their nucleosides. Adv Enzymol Relat Areas Mol Biol (1983) 1.54
T cell antigen receptor engagement stimulates c-raf phosphorylation and induces c-raf-associated kinase activity via a protein kinase C-dependent pathway. J Biol Chem (1990) 1.53
The role of Raf-1 phosphorylation in signal transduction. Adv Cancer Res (1992) 1.53
In vitro malignant transformation by methylcholanthrene of the progeny of single cells derived from C3H mouse prostate. Proc Natl Acad Sci U S A (1970) 1.53
Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells. EMBO Rep (2001) 1.51
Telomerase activity: a biomarker of cell proliferation, not malignant transformation. Proc Natl Acad Sci U S A (1997) 1.51
Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides. Mol Pharmacol (1965) 1.50
Thymidylate synthetase: mechanism of inhibition by 5-fluoro-2'-deoxyuridylate. Biochem Biophys Res Commun (1972) 1.50
Insulin activates the kinase activity of the Raf-1 proto-oncogene by increasing its serine phosphorylation. J Biol Chem (1990) 1.49
Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol. Oncogene (1992) 1.48
Helical nucleocapsid structure of the oncogenic ribonucleic acid viruses (oncornaviruses). J Virol (1971) 1.48
Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein. Cell Growth Differ (2000) 1.46
The Spir actin organizers are involved in vesicle transport processes. Curr Biol (2001) 1.45
A new human T-cell differentiation antigen: unexpected expression on chronic lymphocytic leukemia cells. Immunogenetics (1980) 1.43
Serological and structural properties of Mason-Pfizer monkey virus isolated from the mammary tumor of a Rhesus monkey. Proc Natl Acad Sci U S A (1971) 1.43
Malignant transformation in vitro by carcinogenic hydrocarbons. Science (1967) 1.41
Monoclonal antibodies recognizing normal human T lymphocytes and malignant human B lymphocytes: a comparative study. J Immunol (1981) 1.41
Antibody response of mice to chemically induced tumors. Proc Natl Acad Sci U S A (1978) 1.41
Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction. Mol Cell Biol (1993) 1.40