Published in J Gerontol A Biol Sci Med Sci on March 01, 2006
Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res Rev (2008) 4.14
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev (2008) 2.39
Caloric restriction improves memory in elderly humans. Proc Natl Acad Sci U S A (2009) 2.22
Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res (2008) 1.75
Diet, ageing and genetic factors in the pathogenesis of diverticular disease. World J Gastroenterol (2009) 1.46
SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages. J Biol Chem (2009) 1.39
Caloric restriction: powerful protection for the aging heart and vasculature. Am J Physiol Heart Circ Physiol (2011) 1.35
Comparative analysis of microarray data identifies common responses to caloric restriction among mouse tissues. Mech Ageing Dev (2007) 1.22
Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings. Nutr J (2011) 1.14
Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. PLoS One (2010) 1.09
Effect of exercise and calorie restriction on biomarkers of aging in mice. Am J Physiol Regul Integr Comp Physiol (2008) 1.03
Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis. Exp Neurol (2007) 0.99
Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia. J Gerontol A Biol Sci Med Sci (2011) 0.95
Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives. Clin Geriatr Med (2009) 0.90
Diet and aging. Oxid Med Cell Longev (2012) 0.86
Calorie restriction: progress during mid-2005-mid-2006. Exp Gerontol (2006) 0.85
Circulating endothelial progenitor cells: a new approach to anti-aging medicine? J Transl Med (2009) 0.84
Adult-onset obesity induced by early life overnutrition could be reversed by moderate caloric restriction. Am J Physiol Endocrinol Metab (2013) 0.80
Muscle physiology changes induced by every other day feeding and endurance exercise in mice: effects on physical performance. PLoS One (2010) 0.77
Short-term moderate diet restriction in adulthood can reverse oxidative, cardiovascular and metabolic alterations induced by postnatal overfeeding in mice. Sci Rep (2016) 0.76
Obesity associated with increased brain age from midlife. Neurobiol Aging (2016) 0.76
Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan. Front Genet (2016) 0.75
Calorie restriction for optimal cardiovascular aging: the weight of evidence. Curr Cardiovasc Risk Rep (2010) 0.75
Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB. Sci Rep (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature (2009) 19.56
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis. JAMA (2003) 7.42
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation (2005) 6.89
Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66
Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61
Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54
Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum (2004) 6.46
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell (2010) 5.73
Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67
Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res Rev (2008) 4.14
Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci (2002) 4.00
Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 3.96
Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet (2002) 3.88
Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc (2004) 3.48
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One (2008) 3.25
Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc (2009) 3.12
The effects of cognitive impairment on mortality among hospitalized patients with heart failure. Am J Med (2003) 2.83
The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods. Contemp Clin Trials (2005) 2.79
Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study. Biol Psychiatry (2003) 2.77
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell (2008) 2.65
Measures of physical performance and risk for progressive and catastrophic disability: results from the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci (2005) 2.59
An Aging Interventions Testing Program: study design and interim report. Aging Cell (2007) 2.54
Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study. Am J Epidemiol (2004) 2.49
Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study). Am J Cardiol (2003) 2.49
Effect of intermittent phrenic nerve stimulation during cardiothoracic surgery on mitochondrial respiration in the human diaphragm. Crit Care Med (2014) 2.45
Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study. Am J Clin Nutr (2005) 2.44
Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr (2004) 2.37
Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. Proc Natl Acad Sci U S A (2009) 2.33
Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc (2004) 2.29
Hemoglobin levels and skeletal muscle: results from the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 2.28
The Lifestyle Interventions and Independence for Elders Study: design and methods. J Gerontol A Biol Sci Med Sci (2011) 2.26
Exercise and depressive symptoms: a comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology. J Gerontol B Psychol Sci Soc Sci (2002) 2.22
Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2004) 2.21
Change in physical performance over time in older women: the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci (2002) 2.13
Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study. BMC Geriatr (2008) 2.08
Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial. J Appl Physiol (1985) (2008) 2.06
Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci (2009) 2.03
New insights into the role of mitochondria in aging: mitochondrial dynamics and more. J Cell Sci (2010) 2.03
Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. J Gerontol A Biol Sci Med Sci (2009) 2.02
Skeletal muscle apoptosis, sarcopenia and frailty at old age. Exp Gerontol (2006) 2.01
Walking while talking: effect of task prioritization in the elderly. Arch Phys Med Rehabil (2007) 2.01
Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study. Am J Clin Nutr (2006) 1.97
Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice. Gastroenterology (2011) 1.96
Method for measuring ATP production in isolated mitochondria: ATP production in brain and liver mitochondria of Fischer-344 rats with age and caloric restriction. Am J Physiol Regul Integr Comp Physiol (2003) 1.95
Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ (2005) 1.90
Obese, older adults with knee osteoarthritis: weight loss, exercise, and quality of life. Health Psychol (2002) 1.88
Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring) (2009) 1.88
Lifestyle Interventions and Independence for Elders pilot study: recruitment and baseline characteristics. J Am Geriatr Soc (2007) 1.86
Skeletal muscle and mortality results from the InCHIANTI Study. J Gerontol A Biol Sci Med Sci (2009) 1.86
Reliability of the 400-m usual-pace walk test as an assessment of mobility limitation in older adults. J Am Geriatr Soc (2004) 1.84
Anemia in old age is associated with increased mortality and hospitalization. J Gerontol A Biol Sci Med Sci (2006) 1.83
Age-associated increases in oxidative stress and antioxidant enzyme activities in cardiac interfibrillar mitochondria: implications for the mitochondrial theory of aging. FASEB J (2005) 1.81
C-reactive protein genotypes affect baseline, but not exercise training-induced changes, in C-reactive protein levels. Arterioscler Thromb Vasc Biol (2004) 1.81
Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. J Bone Miner Res (2007) 1.79
Physical performance measures as predictors of mortality in a cohort of community-dwelling older French women. Eur J Epidemiol (2006) 1.76
Lifestyle interventions and independence for elders study: recruitment and baseline characteristics. J Gerontol A Biol Sci Med Sci (2013) 1.75
Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol (2009) 1.74
Consideration of insurance reimbursement for physical activity and exercise programs for patients with diabetes. JAMA (2011) 1.73
Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study. Arch Intern Med (2007) 1.73
Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio. Cancer Res (2002) 1.72
Inflammatory markers and cardiovascular health in older adults. Cardiovasc Res (2005) 1.71
Anemia and decline in physical performance among older persons. Am J Med (2003) 1.70
Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study. Am J Clin Nutr (2004) 1.69
Autophagy in the heart and liver during normal aging and calorie restriction. Rejuvenation Res (2007) 1.66
Muscle fiber specific apoptosis and TNF-alpha signaling in sarcopenia are attenuated by life-long calorie restriction. FASEB J (2005) 1.65
Effects of birth cohort and age on body composition in a sample of community-based elderly. Am J Clin Nutr (2007) 1.65
One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women. J Appl Physiol (1985) (2003) 1.64
Abdominal obesity is an independent risk factor for chronic heart failure in older people. J Am Geriatr Soc (2006) 1.63
A better understanding of why murine models of trauma do not recapitulate the human syndrome. Crit Care Med (2014) 1.62
Blood pressure and decline in kidney function: findings from the Systolic Hypertension in the Elderly Program (SHEP). J Am Soc Nephrol (2002) 1.61
Apoptosis in skeletal muscle with aging. Am J Physiol Regul Integr Comp Physiol (2002) 1.61
Long-term physical activity and inflammatory biomarkers in older adults. Med Sci Sports Exerc (2010) 1.59
Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study). Gerontology (2006) 1.57
Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice. PLoS One (2010) 1.57
Anorexia, physical function, and incident disability among the frail elderly population: results from the ilSIRENTE study. J Am Med Dir Assoc (2010) 1.56
Exercise training and plasma C-reactive protein and interleukin-6 in elderly people. J Am Geriatr Soc (2008) 1.55
Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities. Circ Res (2012) 1.53
Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free Radic Biol Med (2004) 1.46
The Testosterone Trials: Seven coordinated trials of testosterone treatment in elderly men. Clin Trials (2014) 1.46
Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscle. Ageing Res Rev (2006) 1.46
Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions. Cardiovasc Ther (2010) 1.46
Psychomotor speed and functional brain MRI 2 years after completing a physical activity treatment. J Gerontol A Biol Sci Med Sci (2010) 1.45
Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults. J Gerontol A Biol Sci Med Sci (2012) 1.44
Use of angiotensin-converting enzyme inhibitors in elderly people with heart failure: prevalence and outcomes. J Gerontol A Biol Sci Med Sci (2004) 1.43
A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration. Biol Chem (2006) 1.41
Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the Health, Aging, and Body Composition study. Circulation (2004) 1.41
The role of mitochondrial DNA mutations in aging and sarcopenia: implications for the mitochondrial vicious cycle theory of aging. Exp Gerontol (2007) 1.41
Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials. Int J Biochem Cell Biol (2013) 1.38
Metabolic syndrome and physical decline in older persons: results from the Health, Aging And Body Composition Study. J Gerontol A Biol Sci Med Sci (2009) 1.37
Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia. J Cachexia Sarcopenia Muscle (2012) 1.37
The role of apoptosis in the normal aging brain, skeletal muscle, and heart. Ann N Y Acad Sci (2002) 1.36
Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy. Exp Gerontol (2008) 1.36
Antihypertensive medications and differences in muscle mass in older persons: the Health, Aging and Body Composition Study. J Am Geriatr Soc (2004) 1.36