Published in J Biol Chem on March 30, 2006
Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression. Nucleic Acids Res (2008) 1.66
The Mediator complex and transcription regulation. Crit Rev Biochem Mol Biol (2013) 1.64
MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling. Mol Cell Biol (2008) 1.18
MiR-205 silences MED1 in hypoxic primary human trophoblasts. FASEB J (2010) 1.17
p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle (2012) 1.15
Med1 plays a critical role in the development of tamoxifen resistance. Carcinogenesis (2012) 1.13
Retracted Identification of Aurora-A as a direct target of E2F3 during G2/M cell cycle progression. J Biol Chem (2008) 1.04
Varicella-zoster virus IE62 protein utilizes the human mediator complex in promoter activation. J Virol (2008) 1.02
Transcriptional regulation of serine/threonine kinase-15 (STK15) expression by hypoxia and HIF-1. Mol Biol Cell (2008) 0.94
Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells. Horm Cancer (2010) 0.88
Peroxisome-proliferator-activated receptor-binding protein (PBP) is essential for the growth of active Notch4-immortalized mammary epithelial cells by activating SOX10 expression. Biochem J (2009) 0.84
Sense-antisense gene-pairs in breast cancer and associated pathological pathways. Oncotarget (2015) 0.79
Disruption of mediator complex subunit 19 (Med19) inhibits cell growth and migration in tongue cancer. World J Surg Oncol (2013) 0.76
Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1. EMBO J (2003) 3.72
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell (2004) 2.27
Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo. Proc Natl Acad Sci U S A (2002) 1.93
A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression. J Biol Chem (2002) 1.66
A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice. FASEB J (2011) 1.51
Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1. Oncogene (2002) 1.28
Molecular mechanisms of anti-angiogenic effect of curcumin. Biochem Biophys Res Commun (2002) 1.23
MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling. Mol Cell Biol (2008) 1.18
Cyclin-dependent kinase 8 positively cooperates with Mediator to promote thyroid hormone receptor-dependent transcriptional activation. Mol Cell Biol (2010) 1.18
Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation. Mol Cell Biol (2005) 1.13
Nuclear receptor recruitment of histone-modifying enzymes to target gene promoters. Vitam Horm (2004) 1.09
Thyroid hormone-regulated target genes have distinct patterns of coactivator recruitment and histone acetylation. Mol Endocrinol (2005) 1.04
Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway. EMBO Rep (2011) 1.02
A coregulatory role for the mediator complex in prostate cancer cell proliferation and gene expression. Cancer Res (2007) 0.95
A novel androgen receptor-binding element modulates Cdc6 transcription in prostate cancer cells during cell-cycle progression. Nucleic Acids Res (2009) 0.95
The tail-anchoring domain of Bfl1 and HCCS1 targets mitochondrial membrane permeability to induce apoptosis. J Cell Sci (2007) 0.93
Conditional over-expression of estrogen receptor alpha in a transgenic mouse model. Transgenic Res (2002) 0.90
Conversion of Bfl-1, an anti-apoptotic Bcl-2 family protein, to a potent pro-apoptotic protein by fusion with green fluorescent protein (GFP). FEBS Lett (2003) 0.90
Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells. J Biol Chem (2004) 0.88
Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events. Mol Cell Endocrinol (2011) 0.87
Amphipathic tail-anchoring peptide and Bcl-2 homology domain-3 (BH3) peptides from Bcl-2 family proteins induce apoptosis through different mechanisms. J Biol Chem (2010) 0.86
Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif. J Biol Chem (2011) 0.86
Antiangiogenic effects of butyric acid involve inhibition of VEGF/KDR gene expression and endothelial cell proliferation. Mol Cell Biochem (2003) 0.85
Repression of cardiac phospholamban gene expression is mediated by thyroid hormone receptor-{alpha}1 and involves targeted covalent histone modifications. Endocrinology (2010) 0.82
ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity. Mol Cancer Res (2013) 0.82
PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex. PPAR Res (2010) 0.78
Effects of total glycosides from Baishouwu on human breast and prostate cancer cell proliferation. Altern Ther Health Med (2003) 0.77