THE FORMATION OF CONDENSED PHOSPHATE IN AQUEOUS SOLUTION.

PubWeight™: 0.92‹?›

🔗 View Article (PMC 219723)

Published in Proc Natl Acad Sci U S A on September 01, 1965

Authors

A Beck1, L E Orgel

Author Affiliations

1: THE SALK INSTITUTE FOR BIOLOGICAL STUDIES, LA JOLLA, CALIFORNIA.

Articles by these authors

(truncated to the top 100)

Selfish DNA: the ultimate parasite. Nature (1980) 9.85

CODES WITHOUT COMMAS. Proc Natl Acad Sci U S A (1957) 4.28

Evolution of the genetic apparatus. J Mol Biol (1968) 3.77

Synthesis of long prebiotic oligomers on mineral surfaces. Nature (1996) 3.35

Derivatization of unprotected polynucleotides. Nucleic Acids Res (1983) 2.86

Suppression of and complementation among mutants of the regulatory gene of the lactose operon of Escherichia coli. J Mol Biol (1965) 2.32

Detection of specific DNA sequences with short biotin-labeled probes. DNA (1985) 2.13

The case for an ancestral genetic system involving simple analogues of the nucleotides. Proc Natl Acad Sci U S A (1987) 2.12

Oligomerization of (guanosine 5'-phosphor)-2-methylimidazolide on poly(C). An RNA polymerase model. J Mol Biol (1982) 1.88

A nonenzymatic RNA polymerase model. Science (1983) 1.86

Template switching between PNA and RNA oligonucleotides. Nature (1995) 1.84

Ageing of clones of mammalian cells. Nature (1973) 1.80

Beta structures of alternating polypeptides and their possible prebiotic significance. Nature (1975) 1.74

Catalysis of accurate poly(C)-directed synthesis of 3'-5'-linked oligoguanylates by Zn2+. J Mol Biol (1980) 1.74

Nonenzymatic sequence-specific cleavage of single-stranded DNA. Proc Natl Acad Sci U S A (1985) 1.72

Urea-inorganic phosphate mixtures as prebiotic phosphorylating agents. Science (1971) 1.54

Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template. Proc Natl Acad Sci U S A (1968) 1.53

Chiral selection in poly(C)-directed synthesis of oligo(G). Nature (1984) 1.49

Non-enzymatic template-directed synthesis on RNA random copolymers. Poly(C, U) templates. J Mol Biol (1984) 1.41

Autocatalytic synthesis of a tetranucleotide analogue. Nature (1987) 1.38

The maintenance of the accuracy of protein synthesis and its relevance to ageing: a correction. Proc Natl Acad Sci U S A (1970) 1.37

Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides. J Mol Biol (1972) 1.36

Studies in prebiotic synthesis. V. Synthesis and photoanomerization of pyrimidine nucleosides. J Mol Biol (1970) 1.33

In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends. Proc Natl Acad Sci U S A (1995) 1.32

Catalysts for the self-polymerization of adenosine cyclic 2', 3'-phosphate. J Mol Evol (1973) 1.29

The stability of different forms of double-stranded decoy DNA in serum and nuclear extracts. Nucleic Acids Res (1992) 1.26

Oligomerization of activated derivatives of 3'-amino-3'-deoxyguanosine on poly(C) and poly(dC) templates. Nucleic Acids Res (1985) 1.24

Ligation of oligonucleotides to nucleic acids or proteins via disulfide bonds. Nucleic Acids Res (1988) 1.24

Polymerization of nucleotide analogues I: reaction of nucleoside 5'-phosphorimidazolides with 2'-amino-2'-deoxyuridine. J Mol Evol (1976) 1.21

Template-directed synthesis of high molecular weight polynucleotide analogues. Nature (1976) 1.20

Catalysts for the polymerization of adenosine cyclic 2',3'-phosphate on a poly (U) template. Biochim Biophys Acta (1971) 1.20

In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide. J Mol Biol (1970) 1.19

RNA catalysis and the origins of life. J Theor Biol (1986) 1.19

Oligoaminonucleoside phosphoramidates. Oligomerization of dimers of 3'-amino-3'-deoxy-nucleotides (GC and CG) in aqueous solution. Nucleic Acids Res (1987) 1.19

Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues. J Am Chem Soc (1992) 1.17

Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide. J Mol Biol (1967) 1.17

Selfish DNA. Nature (1980) 1.12

Template-directed synthesis of novel, nucleic acid-like structures. Science (1985) 1.12

Origin and ancestor: separate environments. Science (1999) 1.11

PCR with detachable primers. Nucleic Acids Res (1995) 1.09

Studies of oligoadenylate formation on a poly (U) template. J Mol Evol (1979) 1.09

The limits of template-directed synthesis with nucleoside-5'-phosphoro(2-methyl)imidazolides. Orig Life Evol Biosph (1993) 1.08

Cyanoacetylene in prebiotic synthesis. Science (1966) 1.08

Prebiotic synthesis: phosphorylation in aqueous solution. Science (1968) 1.08

Induction of mutations in bacteriophage T4 with divalent manganese. J Mol Biol (1965) 1.07

Template-directed synthesis on the pentanucleotide CpCpGpCpC. J Mol Biol (1984) 1.07

Synthesis of an amplifiable reporter RNA for bioassays. Nucleic Acids Res (1986) 1.06

Studies in prebiotic synthesis: VII. Solid-state synthesis of purine nucleosides. J Mol Evol (1972) 1.06

Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 2. Templates containing cytidine and guanosine residues. J Am Chem Soc (1992) 1.05

Preparation of ligation intermediates and related polynucleotide pyrophosphates. Biochim Biophys Acta (1984) 1.05

Binding of hairpin and dumbbell DNA to transcription factors. Nucleic Acids Res (1991) 1.05

Target-sequence preferences of HIV-1 integration complexes in vitro. Virology (1996) 1.04

Unexpected substrate specificity of T4 DNA ligase revealed by in vitro selection. Nucleic Acids Res (1993) 1.04

Crosslinking transcription factors to their recognition sequences with PtII complexes. Nucleic Acids Res (1992) 1.04

Efficient metal-ion catalyzed template-directed oligonucleotide synthesis. Science (1980) 1.04

Struvite and prebiotic phosphorylation. Science (1973) 1.03

Studies in prebiotic synthesis. 3. Synthesis of pyrimidines from cyanoacetylene and cyanate. J Mol Biol (1968) 1.03

Oligomerization of 3'-amino-3'deoxyguanosine-5'phosphorimidazolidate on a d(CpCpCpCpC) template. J Mol Evol (1987) 1.01

Did template-directed nucleation precede molecular replication? Orig Life Evol Biosph (1986) 1.01

Search for organic and volatile inorganic compounds in two surface samples from the chryse planitia region of Mars. Science (1976) 0.99

An RNA that multiplies indefinitely with DNA-dependent RNA polymerase: selection from a random copolymer. Proc Natl Acad Sci U S A (1973) 0.98

Oxidative acylation using thioacids. Nature (1997) 0.98

Inhibition of DNA synthesis by cross-linking the template to platinum-thiol derivatives of complementary oligodeoxynucleotides. Nucleic Acids Res (1989) 0.96

The formation of dipeptides from amino acids and the 2'(3')-glycyl ester of an adenylate. J Mol Evol (1979) 0.95

Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: the importance of the A structure. J Am Chem Soc (1999) 0.94

Nonenzymatic template-directed synthesis on oligodeoxycytidylate sequences in hairpin oligonucleotides. J Am Chem Soc (1992) 0.94

Template-directed synthesis with adenosine-5'-phosphorimidazolide. Science (1968) 0.93

Prebiotic peptide-formation in the solid state. I. Reactions of benzoate ion and glycine with adenosine 5'-phosphorimidazolide. J Mol Evol (1975) 0.92

Gene-duplication and the origin of proteins with novel functions. J Theor Biol (1977) 0.92

Non-enzymatic transcription of an oligodeoxynucleotide 14 residues long. J Mol Biol (1987) 0.92

Information transfer from peptide nucleic acids to RNA by template-directed syntheses. Nucleic Acids Res (1997) 0.92

Synthesis in sugars in potentially prebiotic conditions. Nature (1967) 0.92

Selection in vitro. Proc R Soc Lond B Biol Sci (1979) 0.91

Oligomerization of activated D- and L-guanosine mononucleotides on templates containing D- and L-deoxycytidylate residues. Proc Natl Acad Sci U S A (1998) 0.91

Letter: Oligonucleotide synthesis catalyzed by the Zn-2+ ion. J Am Chem Soc (1975) 0.91

In vitro selection of optimal DNA substrates for T4 RNA ligase. Proc Natl Acad Sci U S A (1993) 0.90

Prebiotic activation processes. Nature (1973) 0.90

Synthesis of oligoguanylates on oligocytidylate templates. J Mol Evol (1981) 0.90

The action of a water-soluble carbodiimide on adenosine-5'-polyphosphates. Nucleic Acids Res (1987) 0.90

Non-enzymic oligonucleotide synthesis on a polycytidylate template. J Mol Biol (1969) 0.90

Information transfer from DNA to peptide nucleic acids by template-directed syntheses. Nucleic Acids Res (1997) 0.89

A simple procedure for cross-linking complementary oligonucleotides. DNA Cell Biol (1990) 0.89

The catalysis of nucleotide polymerization by compounds of divalent lead. J Mol Evol (1979) 0.89

Aminomalononitrile and 4-amino-5-cyanoimidazole in hydrogen cyanide polymerization and adenine synthesis. J Am Chem Soc (1965) 0.88

Studies on prebiotic synthesis. I. Aminomalononitrile and 4-amino-5-cyanoimidazole. J Am Chem Soc (1966) 0.88

An efficient, sequence-specific method for crosslinking complementary oligonucleotides using binuclear platinum complexes. Nucleic Acids Res (1991) 0.88

Disulfide-linked oligonucleotide phosphorothioates: novel analogues of nucleic acids. J Mol Evol (1991) 0.88

The chemical basis of mutation. Adv Enzymol Relat Areas Mol Biol (1965) 0.87

Optimization of the efficiency of cross-linking PtII oligonucleotide phosphorothioate complexes to complementary oligonucleotides. Nucleic Acids Res (1990) 0.87

A comparison of RNA with DNA in template-directed synthesis. Helv Chim Acta (2000) 0.87

Formation of oligonucleotide-PNA-chimeras by template-directed ligation. J Am Chem Soc (1998) 0.87

Nonenzymatic template-directed reactions on altritol oligomers, preorganized analogues of oligonucleotides. Chemistry (2000) 0.86

Analysis of high molecular weight material from the polymerization of adenosine cyclic 2', 3'-phosphate. J Mol Evol (1974) 0.86

Template-directed oligonucleotide ligation on hydroxylapatite. Nature (1986) 0.86

Efficient catalysis of polycytidylic acid-directed oligoguanylate formation by Pb2+. J Mol Biol (1980) 0.86

Poly(U)-directed peptide-bond formation from the 2'(3')-glycyl esters of adenosine derivatives. J Mol Evol (1980) 0.86

[Nonenzymatic matrix synthesis of RNA from monomers]. Mol Biol (Mosk) (2000) 0.85

Template-directed synthesis of oligoadenylates catalyzed by Pb2+ ions. J Mol Evol (1979) 0.85

Further studies of urea-catalyzed phosphorylation reactions. J Mol Evol (1973) 0.85

Polymerization of the cyclic pyrophosphates of nucleosides and their analogues. J Mol Evol (1990) 0.85