Published in J Mol Biol on December 14, 1967
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Montmorillonite-catalysed formation of RNA oligomers: the possible role of catalysis in the origins of life. Philos Trans R Soc Lond B Biol Sci (2006) 1.26
Mineral surfaces, geochemical complexities, and the origins of life. Cold Spring Harb Perspect Biol (2010) 1.17
Chemoselective multicomponent one-pot assembly of purine precursors in water. J Am Chem Soc (2010) 1.17
The drive to life on wet and icy worlds. Astrobiology (2014) 1.09
The energetics of organic synthesis inside and outside the cell. Philos Trans R Soc Lond B Biol Sci (2013) 0.95
Planetary organic chemistry and the origins of biomolecules. Cold Spring Harb Perspect Biol (2010) 0.93
Ribonucleotides. Cold Spring Harb Perspect Biol (2010) 0.89
Genetic pathways regulating glutamate levels in retinal Müller cells. Neurochem Res (2010) 0.88
Observations of interstellar formamide: availability of a prebiotic precursor in the galactic habitable zone. Astrobiology (2013) 0.86
Accumulation of formamide in hydrothermal pores to form prebiotic nucleobases. Proc Natl Acad Sci U S A (2016) 0.85
Formamide as the main building block in the origin of nucleic acids. BMC Evol Biol (2007) 0.85
Atmospheric Prebiotic Chemistry and Organic Hazes. Curr Org Chem (2013) 0.80
Conversion of biosynthetic precursors of RNA to those of DNA by photoredox chemistry. J Mol Evol (2014) 0.79
Prebiotic chemistry: geochemical context and reaction screening. Life (Basel) (2013) 0.77
Simple Organics and Biomonomers Identified in HCN Polymers: An Overview. Life (Basel) (2013) 0.77
Peptide formation mediated by hydrogen cyanide tetramer: a possible prebiotic process. Proc Natl Acad Sci U S A (1969) 0.75
Selfish DNA: the ultimate parasite. Nature (1980) 9.85
CODES WITHOUT COMMAS. Proc Natl Acad Sci U S A (1957) 4.28
Evolution of the genetic apparatus. J Mol Biol (1968) 3.77
Synthesis of long prebiotic oligomers on mineral surfaces. Nature (1996) 3.35
Derivatization of unprotected polynucleotides. Nucleic Acids Res (1983) 2.86
Suppression of and complementation among mutants of the regulatory gene of the lactose operon of Escherichia coli. J Mol Biol (1965) 2.32
Detection of specific DNA sequences with short biotin-labeled probes. DNA (1985) 2.13
The case for an ancestral genetic system involving simple analogues of the nucleotides. Proc Natl Acad Sci U S A (1987) 2.12
Oligomerization of (guanosine 5'-phosphor)-2-methylimidazolide on poly(C). An RNA polymerase model. J Mol Biol (1982) 1.88
A nonenzymatic RNA polymerase model. Science (1983) 1.86
Template switching between PNA and RNA oligonucleotides. Nature (1995) 1.84
Ageing of clones of mammalian cells. Nature (1973) 1.80
Beta structures of alternating polypeptides and their possible prebiotic significance. Nature (1975) 1.74
Catalysis of accurate poly(C)-directed synthesis of 3'-5'-linked oligoguanylates by Zn2+. J Mol Biol (1980) 1.74
Nonenzymatic sequence-specific cleavage of single-stranded DNA. Proc Natl Acad Sci U S A (1985) 1.72
Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: evidence for the presence of cytochrome P-450. Arch Biochem Biophys (1976) 1.71
Effects of Light Quality on Tiller Production in Lolium spp. Plant Physiol (1983) 1.67
2,2-Anhydropyrimidine nucleosides. Novel syntheses and reactions. J Org Chem (1973) 1.54
Urea-inorganic phosphate mixtures as prebiotic phosphorylating agents. Science (1971) 1.54
Nonenzymatic synthesis of oligoadenylates on a polyuridylic acid template. Proc Natl Acad Sci U S A (1968) 1.53
Chiral selection in poly(C)-directed synthesis of oligo(G). Nature (1984) 1.49
Monooxygenase activity in Cunninghamella bainieri: evidence for a fungal system similar to liver microsomes. Arch Biochem Biophys (1973) 1.44
Non-enzymatic template-directed synthesis on RNA random copolymers. Poly(C, U) templates. J Mol Biol (1984) 1.41
Autocatalytic synthesis of a tetranucleotide analogue. Nature (1987) 1.38
The maintenance of the accuracy of protein synthesis and its relevance to ageing: a correction. Proc Natl Acad Sci U S A (1970) 1.37
Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides. J Mol Biol (1972) 1.36
Studies in prebiotic synthesis. V. Synthesis and photoanomerization of pyrimidine nucleosides. J Mol Biol (1970) 1.33
In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends. Proc Natl Acad Sci U S A (1995) 1.32
HCN: a plausible source of purines, pyrimidines and amino acids on the primitive earth. J Mol Evol (1978) 1.32
Catalysts for the self-polymerization of adenosine cyclic 2', 3'-phosphate. J Mol Evol (1973) 1.29
The stability of different forms of double-stranded decoy DNA in serum and nuclear extracts. Nucleic Acids Res (1992) 1.26
Oligomerization of activated derivatives of 3'-amino-3'-deoxyguanosine on poly(C) and poly(dC) templates. Nucleic Acids Res (1985) 1.24
Ligation of oligonucleotides to nucleic acids or proteins via disulfide bonds. Nucleic Acids Res (1988) 1.24
Polymerization of nucleotide analogues I: reaction of nucleoside 5'-phosphorimidazolides with 2'-amino-2'-deoxyuridine. J Mol Evol (1976) 1.21
Template-directed synthesis of high molecular weight polynucleotide analogues. Nature (1976) 1.20
Catalysts for the polymerization of adenosine cyclic 2',3'-phosphate on a poly (U) template. Biochim Biophys Acta (1971) 1.20
In vitro selection of bacteriophage Q-beta ribonucleic acid variants resistant to ethidium bromide. J Mol Biol (1970) 1.19
Oligoaminonucleoside phosphoramidates. Oligomerization of dimers of 3'-amino-3'-deoxy-nucleotides (GC and CG) in aqueous solution. Nucleic Acids Res (1987) 1.19
RNA catalysis and the origins of life. J Theor Biol (1986) 1.19
Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues. J Am Chem Soc (1992) 1.17
Selfish DNA. Nature (1980) 1.12
Template-directed synthesis of novel, nucleic acid-like structures. Science (1985) 1.12
Origin and ancestor: separate environments. Science (1999) 1.11
Superoxide anion and hydrogen peroxide metabolism in soybean embryonic axes during germination. Biochim Biophys Acta (1991) 1.10
Studies of oligoadenylate formation on a poly (U) template. J Mol Evol (1979) 1.09
PCR with detachable primers. Nucleic Acids Res (1995) 1.09
The limits of template-directed synthesis with nucleoside-5'-phosphoro(2-methyl)imidazolides. Orig Life Evol Biosph (1993) 1.08
Cyanoacetylene in prebiotic synthesis. Science (1966) 1.08
Prebiotic synthesis: phosphorylation in aqueous solution. Science (1968) 1.08
Template-directed synthesis on the pentanucleotide CpCpGpCpC. J Mol Biol (1984) 1.07
Template-directed synthesis using the heterogeneous templates produced by montmorillonite catalysis. A possible bridge between the prebiotic and RNA worlds. J Am Chem Soc (1997) 1.07
Induction of mutations in bacteriophage T4 with divalent manganese. J Mol Biol (1965) 1.07
Synthesis of an amplifiable reporter RNA for bioassays. Nucleic Acids Res (1986) 1.06
Studies in prebiotic synthesis: VII. Solid-state synthesis of purine nucleosides. J Mol Evol (1972) 1.06
Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 2. Templates containing cytidine and guanosine residues. J Am Chem Soc (1992) 1.05
Preparation of ligation intermediates and related polynucleotide pyrophosphates. Biochim Biophys Acta (1984) 1.05
Binding of hairpin and dumbbell DNA to transcription factors. Nucleic Acids Res (1991) 1.05
Target-sequence preferences of HIV-1 integration complexes in vitro. Virology (1996) 1.04
Unexpected substrate specificity of T4 DNA ligase revealed by in vitro selection. Nucleic Acids Res (1993) 1.04
Efficient metal-ion catalyzed template-directed oligonucleotide synthesis. Science (1980) 1.04
Crosslinking transcription factors to their recognition sequences with PtII complexes. Nucleic Acids Res (1992) 1.04
Synthesis of RNA oligomers on heterogeneous templates. Nature (1996) 1.04
Struvite and prebiotic phosphorylation. Science (1973) 1.03
Studies in prebiotic synthesis. 3. Synthesis of pyrimidines from cyanoacetylene and cyanate. J Mol Biol (1968) 1.03
Oligomerization of 3'-amino-3'deoxyguanosine-5'phosphorimidazolidate on a d(CpCpCpCpC) template. J Mol Evol (1987) 1.01
Did template-directed nucleation precede molecular replication? Orig Life Evol Biosph (1986) 1.01
Search for organic and volatile inorganic compounds in two surface samples from the chryse planitia region of Mars. Science (1976) 0.99
An RNA that multiplies indefinitely with DNA-dependent RNA polymerase: selection from a random copolymer. Proc Natl Acad Sci U S A (1973) 0.98
Oxidative acylation using thioacids. Nature (1997) 0.98
Inhibition of DNA synthesis by cross-linking the template to platinum-thiol derivatives of complementary oligodeoxynucleotides. Nucleic Acids Res (1989) 0.96
Kinetic and mechanistic analysis of dinucleotide and oligonucleotide formation from the 5'-phosphorimidazolide of adenosine on Na(+)-montmorillonite. J Am Chem Soc (1994) 0.95
Marine hydrothermal systems and the origin of life: future research. Orig Life Evol Biosph (1992) 0.95
Adenine derivatives as phosphate-activating groups for the regioselective formation of 3',5'-linked oligoadenylates on montmorillonite: possible phosphate-activating groups for the prebiotic synthesis of RNA. J Am Chem Soc (1997) 0.95
The formation of dipeptides from amino acids and the 2'(3')-glycyl ester of an adenylate. J Mol Evol (1979) 0.95
Nonenzymatic template-directed synthesis on oligodeoxycytidylate sequences in hairpin oligonucleotides. J Am Chem Soc (1992) 0.94
Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: the importance of the A structure. J Am Chem Soc (1999) 0.94
Template-directed synthesis with adenosine-5'-phosphorimidazolide. Science (1968) 0.93
Prebiotic peptide-formation in the solid state. I. Reactions of benzoate ion and glycine with adenosine 5'-phosphorimidazolide. J Mol Evol (1975) 0.92
THE FORMATION OF CONDENSED PHOSPHATE IN AQUEOUS SOLUTION. Proc Natl Acad Sci U S A (1965) 0.92
Gene-duplication and the origin of proteins with novel functions. J Theor Biol (1977) 0.92
Information transfer from peptide nucleic acids to RNA by template-directed syntheses. Nucleic Acids Res (1997) 0.92
Non-enzymatic transcription of an oligodeoxynucleotide 14 residues long. J Mol Biol (1987) 0.92
Synthesis in sugars in potentially prebiotic conditions. Nature (1967) 0.92
Structural studies on HCN oligomers. J Mol Evol (1981) 0.91
Selection in vitro. Proc R Soc Lond B Biol Sci (1979) 0.91
Oligomerization of activated D- and L-guanosine mononucleotides on templates containing D- and L-deoxycytidylate residues. Proc Natl Acad Sci U S A (1998) 0.91
Letter: Oligonucleotide synthesis catalyzed by the Zn-2+ ion. J Am Chem Soc (1975) 0.91
Synthesis of oligoguanylates on oligocytidylate templates. J Mol Evol (1981) 0.90
The action of a water-soluble carbodiimide on adenosine-5'-polyphosphates. Nucleic Acids Res (1987) 0.90
In vitro selection of optimal DNA substrates for T4 RNA ligase. Proc Natl Acad Sci U S A (1993) 0.90
Prebiotic activation processes. Nature (1973) 0.90
Non-enzymic oligonucleotide synthesis on a polycytidylate template. J Mol Biol (1969) 0.90
A simple procedure for cross-linking complementary oligonucleotides. DNA Cell Biol (1990) 0.89