Outer membrane protein A of Escherichia coli O157:H7 stimulates dendritic cell activation.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMC 1459721)

Published in Infect Immun on May 01, 2006

Authors

Alfredo G Torres1, Yongguo Li, Christopher B Tutt, Lijun Xin, Tonyia Eaves-Pyles, Lynn Soong

Author Affiliations

1: Department of Microbiology and Immunology, 301 University Blvd., University of Texas Medical Branch, Galveston, Texas 77555-1070, USA. altorres@utmb.edu

Articles citing this

The OmpA-like protein Loa22 is essential for leptospiral virulence. PLoS Pathog (2007) 1.93

Mass spectrometry defines the C-terminal dimerization domain and enables modeling of the structure of full-length OmpA. Structure (2014) 1.59

Outer membrane protein A and OprF: versatile roles in Gram-negative bacterial infections. FEBS J (2012) 1.10

OmpA of uropathogenic Escherichia coli promotes postinvasion pathogenesis of cystitis. Infect Immun (2009) 1.08

Infection strategies of enteric pathogenic Escherichia coli. Gut Microbes (2012) 1.06

Structural modifications of outer membrane vesicles to refine them as vaccine delivery vehicles. Biochim Biophys Acta (2009) 0.99

Outer membrane protein A (OmpA) of Shigella flexneri 2a, induces protective immune response in a mouse model. PLoS One (2011) 0.94

Outer membrane protein A (OmpA) of Shigella flexneri 2a links innate and adaptive immunity in a TLR2-dependent manner and involvement of IL-12 and nitric oxide. J Biol Chem (2012) 0.90

Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines. Microbiol Mol Biol Rev (2013) 0.87

Transcriptional regulation of the ecp operon by EcpR, IHF, and H-NS in attaching and effacing Escherichia coli. J Bacteriol (2012) 0.85

Differential uptake and processing of a Haemophilus influenzae P5-derived immunogen by chinchilla dendritic cells. Infect Immun (2007) 0.83

Outer membrane protein A (OmpA) of Shigella flexneri 2a induces TLR2-mediated activation of B cells: involvement of protein tyrosine kinase, ERK and NF-κB. PLoS One (2014) 0.78

EHEC Adhesins. Microbiol Spectr (2015) 0.77

The periplasmic enzyme, AnsB, of Shigella flexneri modulates bacterial adherence to host epithelial cells. PLoS One (2014) 0.75

The Escherichia coli O157:H7 cattle immunoproteome includes outer membrane protein A (OmpA), a modulator of adherence to bovine rectoanal junction squamous epithelial (RSE) cells. Proteomics (2015) 0.75

Protective Immunity Elicited by Oral Immunization of Mice with Salmonella enterica Serovar Typhimurium Braun Lipoprotein (Lpp) and Acetyltransferase (MsbB) Mutants. Front Cell Infect Microbiol (2016) 0.75

Computational Analysis of Host-Pathogen Protein Interactions between Humans and Different Strains of Enterohemorrhagic Escherichia coli. Front Cell Infect Microbiol (2017) 0.75

In-silico design, expression, and purification of novel chimeric Escherichia coli O157:H7 OmpA fused to LTB protein in Escherichia coli. PLoS One (2017) 0.75

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A (2000) 96.90

High efficiency transformation of E. coli by high voltage electroporation. Nucleic Acids Res (1988) 34.78

Diarrheagenic Escherichia coli. Clin Microbiol Rev (1998) 30.09

Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines. Infect Immun (1983) 12.81

Toll-like receptors in the induction of the innate immune response. Nature (2000) 12.23

Pathogenesis and diagnosis of Shiga toxin-producing Escherichia coli infections. Clin Microbiol Rev (1998) 8.74

Pathogenesis of escherichia coli gastroenteritis in man--another mechanism. N Engl J Med (1980) 8.01

Cell envelope and shape of Escherichia coli: multiple mutants missing the outer membrane lipoprotein and other major outer membrane proteins. J Bacteriol (1978) 3.57

Outer membrane protein A of Escherichia coli contributes to invasion of brain microvascular endothelial cells. Infect Immun (1996) 3.53

Genotypic variation in pathogenic Escherichia coli O157:H7 isolated from patients in Washington, 1984-1987. J Infect Dis (1989) 3.50

Action of a major outer cell envelope membrane protein in conjugation of Escherichia coli K-12. J Bacteriol (1977) 2.27

Identification and characterization of lpfABCC'DE, a fimbrial operon of enterohemorrhagic Escherichia coli O157:H7. Infect Immun (2002) 2.18

Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells. Proc Natl Acad Sci U S A (2001) 2.12

Multiple elements controlling adherence of enterohemorrhagic Escherichia coli O157:H7 to HeLa cells. Infect Immun (2003) 1.97

Adherence of diarrheagenic Escherichia coli strains to epithelial cells. Infect Immun (2005) 1.89

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity (2005) 1.86

Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. Am J Physiol Gastrointest Liver Physiol (2001) 1.81

Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis. Infect Immun (2003) 1.74

Dendritic cell biology and regulation of dendritic cell trafficking by chemokines. Springer Semin Immunopathol (2000) 1.72

Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expression. Infect Immun (2001) 1.69

Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cells. Infect Immun (1999) 1.66

Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell Microbiol (2002) 1.54

Identification of Escherichia coli outer membrane protein A receptor on human brain microvascular endothelial cells. Infect Immun (2002) 1.53

Cytokines in host defense against Salmonella. Microbes Infect (2001) 1.48

Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the protein. J Immunol (2001) 1.46

Fc gamma receptors and cross-presentation in dendritic cells. J Exp Med (2002) 1.43

OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway. Nat Immunol (2000) 1.43

Characterization of the second long polar (LP) fimbriae of Escherichia coli O157:H7 and distribution of LP fimbriae in other pathogenic E. coli strains. FEMS Microbiol Lett (2004) 1.43

Leishmania amazonensis-dendritic cell interactions in vitro and the priming of parasite-specific CD4(+) T cells in vivo. J Immunol (2001) 1.36

A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation. J Immunol (2003) 1.34

Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cells. J Immunol (2004) 1.33

Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo. Cell Microbiol (2006) 1.29

Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles. Infect Immun (2003) 1.27

Structure and function of pore-forming beta-barrels from bacteria. J Mol Microbiol Biotechnol (2002) 1.24

Dendritic cells and host resistance to infection. Cell Microbiol (2003) 1.24

Outer membrane protein A (OmpA): a new pathogen-associated molecular pattern that interacts with antigen presenting cells-impact on vaccine strategies. Vaccine (2002) 1.20

Enhanced CXC chemokine responses of human colonic epithelial cells to locus of enterocyte effacement-negative shiga-toxigenic Escherichia coli. Infect Immun (2003) 1.19

Outer membrane protein A (OmpA) binds to and activates human macrophages. J Immunol (2000) 1.18

Escherichia coli outer membrane protein A adheres to human brain microvascular endothelial cells. Biochem Biophys Res Commun (2005) 1.15

The C-terminal domain of Salmonella enterica serovar typhimurium OmpA is an immunodominant antigen in mice but appears to be only partially exposed on the bacterial cell surface. Infect Immun (2003) 1.09

Structure and function of the intestinal epithelial barrier in health and disease. Monogr Pathol (1990) 1.04

Accelerated antigen presentation and elicitation of humoral response in vivo by FcgammaRIIB- and FcgammaRI/III-mediated immune complex uptake. Cell Immunol (2003) 1.02

Antibodies against listerial protein 60 act as an opsonin for phagocytosis of Listeria monocytogenes by human dendritic cells. Infect Immun (2001) 0.94

Escherichia coli Shiga toxin. J Nat Toxins (2000) 0.94

Dendritic cells: the host Achille's heel for mucosal pathogens? Trends Microbiol (2004) 0.91

Outer membrane protein A renders dendritic cells and macrophages responsive to CCL21 and triggers dendritic cell migration to secondary lymphoid organs. Eur J Immunol (2003) 0.90

Bacterial outer membrane protein vaccines. The meningococcal example. Adv Exp Med Biol (1996) 0.88

Is immune cell activation the missing link in the pathogenesis of post-diarrhoeal HUS? Trends Microbiol (2001) 0.85

Articles by these authors

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection. Nature (2013) 3.03

Pregnancy imprints regulatory memory that sustains anergy to fetal antigen. Nature (2012) 2.11

Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis. Infect Immun (2003) 1.74

Potentiation of West Nile encephalitis by mosquito feeding. Viral Immunol (2006) 1.62

Differential, type I interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver. Gastroenterology (2011) 1.52

Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of Francisella leads to activation of immature DC and intracellular survival of the bacteria. J Leukoc Biol (2006) 1.47

CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection. J Immunol (2005) 1.46

Aedes aegypti salivary gland extracts modulate anti-viral and TH1/TH2 cytokine responses to sindbis virus infection. Viral Immunol (2004) 1.44

Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells. Int J Med Microbiol (2007) 1.44

Overproduction of TNF-alpha by CD8+ type 1 cells and down-regulation of IFN-gamma production by CD4+ Th1 cells contribute to toxic shock-like syndrome in an animal model of fatal monocytotropic ehrlichiosis. J Immunol (2004) 1.43

Characterization of the second long polar (LP) fimbriae of Escherichia coli O157:H7 and distribution of LP fimbriae in other pathogenic E. coli strains. FEMS Microbiol Lett (2004) 1.43

Sand fly saliva enhances Leishmania amazonensis infection by modulating interleukin-10 production. Infect Immun (2004) 1.35

Enhanced replication of Leishmania amazonensis amastigotes in gamma interferon-stimulated murine macrophages: implications for the pathogenesis of cutaneous leishmaniasis. Infect Immun (2004) 1.33

Analysis of T helper cell responses during infection with Leishmania amazonensis. Am J Trop Med Hyg (2002) 1.28

Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles. Infect Immun (2003) 1.27

Leishmania braziliensis infection induces dendritic cell activation, ISG15 transcription, and the generation of protective immune responses. J Immunol (2008) 1.25

Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice. Infect Immun (2009) 1.24

L-arginine metabolism and its impact on host immunity against Leishmania infection. Immunol Res (2008) 1.21

Prior exposure to uninfected mosquitoes enhances mortality in naturally-transmitted West Nile virus infection. PLoS One (2007) 1.21

Leishmania model for microbial virulence: the relevance of parasite multiplication and pathoantigenicity. Acta Trop (2003) 1.20

Down-regulation of dendritic cell signaling pathways by Leishmania amazonensis amastigotes. Mol Immunol (2008) 1.20

Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody. Vaccine (2008) 1.19

Cooperation between apoptotic and viable metacyclics enhances the pathogenesis of Leishmaniasis. PLoS One (2009) 1.17

Perforin and gamma interferon are critical CD8+ T-cell-mediated responses in vaccine-induced immunity against Leishmania amazonensis infection. Infect Immun (2003) 1.16

Pathogenic role of B cells and antibodies in murine Leishmania amazonensis infection. Int J Parasitol (2007) 1.15

Role of interleukin-1beta in activating the CD11c(high) CD45RB- dendritic cell subset and priming Leishmania amazonensis-specific CD4+ T cells in vitro and in vivo. Infect Immun (2007) 1.13

CXCL10/gamma interferon-inducible protein 10-mediated protection against Leishmania amazonensis infection in mice. Infect Immun (2006) 1.09

DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous Leishmaniasis. Infect Immun (2003) 1.09

Role of primary human alveolar epithelial cells in host defense against Francisella tularensis infection. Infect Immun (2007) 1.08

L-arginine and cationic amino acid transporter 2B regulate growth and survival of Leishmania amazonensis amastigotes in macrophages. Infect Immun (2007) 1.08

Differential microbicidal effects of human histone proteins H2A and H2B on Leishmania promastigotes and amastigotes. Infect Immun (2010) 1.07

Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites. J Immunol (2010) 1.06

Functional interferon system is required for clearance of lassa virus. J Virol (2012) 1.05

Antigenic diversity in maxadilan, a salivary protein from the sand fly vector of American visceral leishmaniasis. Am J Trop Med Hyg (2004) 1.04

CXCL10 production by human monocytes in response to Leishmania braziliensis infection. Infect Immun (2009) 1.03

Aedes aegypti saliva alters leukocyte recruitment and cytokine signaling by antigen-presenting cells during West Nile virus infection. PLoS One (2010) 1.02

IL-33 induces nuocytes and modulates liver injury in viral hepatitis. J Immunol (2013) 1.01

Degradation of host sphingomyelin is essential for Leishmania virulence. PLoS Pathog (2009) 1.00

gammadelta T cells promote the maturation of dendritic cells during West Nile virus infection. FEMS Immunol Med Microbiol (2010) 1.00

Differential interaction of dendritic cells with Rickettsia conorii: impact on host susceptibility to murine spotted fever rickettsiosis. Infect Immun (2007) 0.99

Protection Afforded by Fluoroquinolones in Animal Models of Respiratory Infections with Bacillus anthracis, Yersinia pestis, and Francisella tularensis. Open Microbiol J (2010) 0.98

Negative effect of antibodies against maxadilan on the fitness of the sand fly vector of American visceral leishmaniasis. Am J Trop Med Hyg (2004) 0.97

Leishmania major heat shock protein 70 (HSP70) is not protective in murine models of cutaneous leishmaniasis and stimulates strong humoral responses in cutaneous and visceral leishmaniasis patients. Vaccine (2007) 0.97

Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis. J Immunol (2012) 0.95

Role of natural killer cells in modulating dendritic cell responses to Leishmania amazonensis infection. Infect Immun (2008) 0.95

CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells. Biol Direct (2009) 0.94

Differential requirement for CD18 in T-helper effector homing. Nat Med (2003) 0.94

Up-regulated MicroRNA-181a induces carcinogenesis in hepatitis B virus-related hepatocellular carcinoma by targeting E2F5. BMC Cancer (2014) 0.94

Rickettsiae stimulate dendritic cells through toll-like receptor 4, leading to enhanced NK cell activation in vivo. J Infect Dis (2009) 0.93

Interferon gamma in leishmaniasis. Front Immunol (2013) 0.92

Downregulation of microRNA-107 in intestinal CD11c(+) myeloid cells in response to microbiota and proinflammatory cytokines increases IL-23p19 expression. Eur J Immunol (2014) 0.91

Rickettsiae-stimulated dendritic cells mediate protection against lethal rickettsial challenge in an animal model of spotted fever rickettsiosis. J Infect Dis (2007) 0.90

Bile salts induce expression of the afimbrial LDA adhesin of atypical enteropathogenic Escherichia coli. Cell Microbiol (2007) 0.90

Effects of CXCL10 on dendritic cell and CD4+ T-cell functions during Leishmania amazonensis infection. Infect Immun (2007) 0.90

Listeria monocytogenes cytoplasmic entry induces fetal wastage by disrupting maternal Foxp3+ regulatory T cell-sustained fetal tolerance. PLoS Pathog (2012) 0.89

Extraction and ultra-performance liquid chromatography of hydrophilic and lipophilic bioactive components in a Chinese herb Radix Salviae Miltiorrhizae. J Chromatogr A (2007) 0.89

Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice. Hepatology (2011) 0.89

Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host. Infect Immun (2011) 0.89

Exposure of phosphatidylserine on Leishmania amazonensis isolates is associated with diffuse cutaneous leishmaniasis and parasite infectivity. PLoS One (2012) 0.88

B7H1-Ig fusion protein activates the CD4+ IFN-gamma receptor+ type 1 T regulatory subset through IFN-gamma-secreting Th1 cells. J Immunol (2006) 0.88

CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage. J Clin Invest (2015) 0.87

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms. Infect Immun (2013) 0.87

Pathoadaptive mutation that mediates adherence of shiga toxin-producing Escherichia coli O111. Infect Immun (2005) 0.87

Leishmania mexicana infection of the eyelid in a traveler to Belize. Braz J Infect Dis (2007) 0.86

MHC class II transactivator represses human IL-4 gene transcription by interruption of promoter binding with CBP/p300, STAT6 and NFAT1 via histone hypoacetylation. Immunology (2007) 0.86

Yellow fever virus infection in Syrian golden hamsters: relationship between cytokine expression and pathologic changes. Int J Clin Exp Pathol (2008) 0.85

Testing the efficacy and toxicity of adenylyl cyclase inhibitors against enteric pathogens using in vitro and in vivo models of infection. Infect Immun (2010) 0.85

Systemic treatment with CpG-B after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (IDO). PLoS One (2012) 0.85

Heat shock inhibits activation of NF-kappaB in the absence of heat shock factor-1. Biochem Biophys Res Commun (2002) 0.85

A Quasi species of the pre-S/S gene and mutations of enhancer II/core promoter/pre-C in mothers and their children infected with hepatitis B virus via mother-to-infant transmission. J Infect Dis (2005) 0.84

Comparative two-dimensional gel electrophoresis maps for promastigotes of Leishmania amazonensis and Leishmania major. Braz J Infect Dis (2006) 0.83

Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy. Cell Mol Immunol (2014) 0.82

Identification and characterization of "pathoadaptive mutations" of the cadBA operon in several intestinal Escherichia coli. Int J Med Microbiol (2006) 0.82

Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. J Immunol (2014) 0.82

IFN-α/β and autophagy: tug-of-war between HCV and the host. Autophagy (2011) 0.82

Regulatory T cells and the immune pathogenesis of prenatal infection. Reproduction (2013) 0.81

[Expression of checkpoint kinase 1 and polo-like kinase 1 and its clinicopathological significance in benign and malignant lesions of the stomach]. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2010) 0.81

B7-1/B7-2 blockade overrides the activation of protective CD8 T cells stimulated in the absence of Foxp3+ regulatory T cells. J Leukoc Biol (2013) 0.81

Influence of nuclear factor kappaB activation on inflammatory mediators of alveolar macrophages in rats with acute necrotizing pancreatitis. J Investig Med (2010) 0.81

Burkholderia mallei and Burkholderia pseudomallei stimulate differential inflammatory responses from human alveolar type II cells (ATII) and macrophages. Front Cell Infect Microbiol (2012) 0.80

Association of survivin polymorphisms with tumor susceptibility: a meta-analysis. PLoS One (2013) 0.80

The C-terminal extension of Leishmania pifanoi amastigote-specific cysteine proteinase Lpcys2: a putative function in macrophage infection. Mol Biochem Parasitol (2008) 0.80

Immunization of mice with T cell-dependent antigens promotes IL-6 and TNF-alpha production in muscle cells. Cytokine (2006) 0.79

Effects of flagellin on the functions of follicle-associated epithelium. J Infect Dis (2008) 0.79

Preventive effects of nitroglycerine on glucocorticoid-induced osteoporosis in growing rats. J Huazhong Univ Sci Technolog Med Sci (2007) 0.79

Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance. J Innate Immun (2015) 0.78

Leishmania mexicana infection of the eyelid in a traveler to Belize. Braz J Infect Dis (2006) 0.78

A variant in the promoter of MBL2 is associated with protection against visceral leishmaniasis in Morocco. Infect Genet Evol (2012) 0.78

Establishing a liquid-phase IEF in combination with 2-DE for the analysis of Leishmania proteins. Proteomics (2007) 0.78

Novel SLA-DQ alleles and their recombinant molecules in xenogeneic stimulation of human T cells. Transpl Immunol (2005) 0.78

Phenotypic alterations of dendritic cells are involved in suppressive activity of trichosanthin-induced CD8+CD28- regulatory T cells. J Immunol (2010) 0.77

Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis. Mol Med (2013) 0.76