Published in Contemp Clin Trials on April 19, 2006
Ginkgo Biloba Prevention Trial in Older Individuals | NCT00010803
Ginkgo biloba for prevention of dementia: a randomized controlled trial. JAMA (2008) 6.00
Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors. Lancet Neurol (2008) 4.14
Antihypertensive drugs decrease risk of Alzheimer disease: Ginkgo Evaluation of Memory Study. Neurology (2013) 2.61
Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial. JAMA (2009) 2.59
Alzheimer's prevention initiative: a proposal to evaluate presymptomatic treatments as quickly as possible. Biomark Med (2010) 2.17
A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive decline. Neurology (2008) 1.91
Arterial stiffness and β-amyloid progression in nondemented elderly adults. JAMA Neurol (2014) 1.63
Infection hospitalization increases risk of dementia in the elderly. Crit Care Med (2014) 1.43
Functional and cognitive criteria produce different rates of mild cognitive impairment and conversion to dementia. J Neurol Neurosurg Psychiatry (2009) 1.43
Heme oxygenase 1, beneficial role in permanent ischemic stroke and in Gingko biloba (EGb 761) neuroprotection. Neuroscience (2011) 1.20
Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models. Free Radic Biol Med (2008) 1.19
Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults. Neurology (2013) 1.18
In vivo assessment of amyloid-β deposition in nondemented very elderly subjects. Ann Neurol (2013) 1.17
Personality and risk for Alzheimer's disease in adults 72 years of age and older: a 6-year follow-up. Psychol Aging (2011) 1.14
Statins, risk of dementia, and cognitive function: secondary analysis of the ginkgo evaluation of memory study. J Stroke Cerebrovasc Dis (2011) 1.12
Cognitive trajectories associated with β-amyloid deposition in the oldest-old without dementia. Neurology (2013) 1.11
Modifiable Midlife Risk Factors for Late-Life Cognitive Impairment and Dementia. Curr Psychiatry Rev (2009) 1.09
Effect of plant extracts on Alzheimer's disease: An insight into therapeutic avenues. J Neurosci Rural Pract (2011) 1.09
Combining Multiple Markers to Improve the Longitudinal Rate of Progression-Application to Clinical Trials on the Early Stage of Alzheimer's Disease. Stat Biopharm Res (2013) 1.03
Commentary on "a roadmap for the prevention of dementia II: Leon Thal Symposium 2008." Prevention trials in persons at risk for dominantly inherited Alzheimer's disease: opportunities and challenges. Alzheimers Dement (2009) 1.02
Identifying mild cognitive impairment at baseline in the Ginkgo Evaluation of Memory (GEM) study. Aging Ment Health (2009) 1.02
Personality and medication non-adherence among older adults enrolled in a six-year trial. Br J Health Psychol (2011) 1.01
Telephone interview for cognitive status (TICS) screening for clinical trials of physical activity and cognitive training: the seniors health and activity research program pilot (SHARP-P) study. Int J Geriatr Psychiatry (2011) 0.97
Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. J Alzheimers Dis (2008) 0.95
Does Ginkgo biloba reduce the risk of cardiovascular events? Circ Cardiovasc Qual Outcomes (2009) 0.90
Ginkgo biloba: an adjuvant therapy for progressive normal and high tension glaucoma. Mol Vis (2012) 0.89
Alternative medicine and Alzheimer disease. Neurologist (2008) 0.87
An overview of the design, implementation, and analyses of longitudinal studies on aging. J Am Geriatr Soc (2010) 0.87
Markers of cholesterol transport are associated with amyloid deposition in the brain. Neurobiol Aging (2013) 0.87
Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba. Food Nutr Res (2010) 0.85
Personality factors moderate the associations between apolipoprotein genotype and cognitive function as well as late onset Alzheimer disease. Am J Geriatr Psychiatry (2012) 0.84
Ginkgo biloba and risk of cancer: secondary analysis of the Ginkgo Evaluation of Memory (GEM) Study. Pharmacoepidemiol Drug Saf (2010) 0.83
Alterations in the red blood cell membrane proteome in alzheimer's subjects reflect disease-related changes and provide insight into altered cell morphology. Proteome Sci (2010) 0.81
Gene by neuroticism interaction and cognitive function among older adults. Int J Geriatr Psychiatry (2012) 0.79
Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J. Neurobiol Aging (2007) 0.79
EGb761 protects motoneurons against avulsion-induced oxidative stress in rats. J Brachial Plex Peripher Nerve Inj (2010) 0.77
Diuretic use is associated with better learning and memory in older adults in the Ginkgo Evaluation of Memory Study. Alzheimers Dement (2012) 0.77
Associations Between Mild Cognitive Impairment and Hospitalization and Readmission. J Am Geriatr Soc (2015) 0.77
Embedding clinical interventions into observational studies. Contemp Clin Trials (2015) 0.77
Repair and regeneration properties of Ginkgo biloba after ischemic brain injury. Neural Regen Res (2014) 0.75
Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities. Neuroimage Clin (2015) 0.75
Subsets of a large cognitive battery better power clinical trials on early stage Alzheimer's disease. Neuroepidemiology (2014) 0.75
Is risk of Alzheimer disease a reason to use dietary supplements? Am J Clin Nutr (2010) 0.75
Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol (2002) 35.63
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA (2004) 23.69
Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med (2008) 18.34
Inflammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med (2008) 13.72
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73
Estrogen therapy and coronary-artery calcification. N Engl J Med (2007) 8.70
Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med (2011) 8.19
Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA (2010) 7.12
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Ginkgo biloba for prevention of dementia: a randomized controlled trial. JAMA (2008) 6.00
HIV infection and the risk of acute myocardial infarction. JAMA Intern Med (2013) 5.90
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection. J Infect Dis (2010) 5.35
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94
Developing a national strategy to prevent dementia: Leon Thal Symposium 2009. Alzheimers Dement (2010) 4.85
Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1. Arch Neurol (2003) 4.82
Breast cancer after use of estrogen plus progestin in postmenopausal women. N Engl J Med (2009) 4.80
Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial. JAMA (2003) 4.07
Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet (2002) 3.88
Differences in the incidence of congestive heart failure by ethnicity: the multi-ethnic study of atherosclerosis. Arch Intern Med (2008) 3.76
Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation (2006) 3.69
Inflammation, coagulation and cardiovascular disease in HIV-infected individuals. PLoS One (2012) 3.68
Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the Cardiovascular Health Study. Arch Gen Psychiatry (2006) 3.61
Depression and cardiovascular sequelae in postmenopausal women. The Women's Health Initiative (WHI). Arch Intern Med (2004) 3.59
Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women's Health Initiative randomised placebo-controlled trial. Lancet Oncol (2012) 3.56
Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathol (2007) 3.55
Proton pump inhibitor use, hip fracture, and change in bone mineral density in postmenopausal women: results from the Women's Health Initiative. Arch Intern Med (2010) 3.53
Thyroid status, cardiovascular risk, and mortality in older adults. JAMA (2006) 3.50
Estrogen plus progestin and risk of venous thrombosis. JAMA (2004) 3.46
Incidence and prevalence of dementia in the Cardiovascular Health Study. J Am Geriatr Soc (2004) 3.43
Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause. Am J Epidemiol (2009) 3.33
Use of nonsteroidal antiinflammatory drugs: an update for clinicians: a scientific statement from the American Heart Association. Circulation (2007) 3.27
Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events. JAMA (2006) 3.26
Association between lower digit symbol substitution test score and slower gait and greater risk of mortality and of developing incident disability in well-functioning older adults. J Am Geriatr Soc (2008) 3.21
Lp(a) lipoprotein, vascular disease, and mortality in the elderly. N Engl J Med (2003) 3.20
Evaluation of dementia in the cardiovascular health cognition study. Neuroepidemiology (2003) 3.19
Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). JAMA (2002) 3.13
Rapid decline of kidney function increases cardiovascular risk in the elderly. J Am Soc Nephrol (2009) 3.12
Physical activity, APOE genotype, and dementia risk: findings from the Cardiovascular Health Cognition Study. Am J Epidemiol (2005) 3.10
Optimism, cynical hostility, and incident coronary heart disease and mortality in the Women's Health Initiative. Circulation (2009) 3.09
Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort. J Am Geriatr Soc (2005) 3.07
The long-term effects of conventional and atypical antipsychotics in patients with probable Alzheimer's disease. Am J Psychiatry (2013) 3.06
Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study. Am J Epidemiol (2008) 3.05
Brain structure and obesity. Hum Brain Mapp (2010) 3.04
Oophorectomy vs ovarian conservation with hysterectomy: cardiovascular disease, hip fracture, and cancer in the Women's Health Initiative Observational Study. Arch Intern Med (2011) 3.00
Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 2.97
Risk factors for dementia in the cardiovascular health cognition study. Neuroepidemiology (2003) 2.97
HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr (2012) 2.95
Prevalence of age-related macular degeneration in 4 racial/ethnic groups in the multi-ethnic study of atherosclerosis. Ophthalmology (2006) 2.95
Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study. Circulation (2007) 2.93
Cardiac benefits of fish consumption may depend on the type of fish meal consumed: the Cardiovascular Health Study. Circulation (2003) 2.88
Accelerated loss of skeletal muscle strength in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes Care (2007) 2.87
Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancer. J Natl Cancer Inst (2011) 2.84
Renal insufficiency as a predictor of cardiovascular outcomes and mortality in elderly individuals. J Am Coll Cardiol (2003) 2.83
Moderate renal impairment and risk of dementia among older adults: the Cardiovascular Health Cognition Study. J Am Soc Nephrol (2004) 2.82
Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study. Arch Intern Med (2009) 2.82
n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study. Am J Clin Nutr (2003) 2.82
Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline. Proc Natl Acad Sci U S A (2005) 2.79
Midlife and late-life obesity and the risk of dementia: cardiovascular health study. Arch Neurol (2009) 2.79
Estrogen plus progestin therapy and breast cancer in recently postmenopausal women. Am J Epidemiol (2008) 2.79
Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study. J Am Coll Cardiol (2008) 2.74
Novel metabolic risk factors for incident heart failure and their relationship with obesity: the MESA (Multi-Ethnic Study of Atherosclerosis) study. J Am Coll Cardiol (2008) 2.74
Sleep duration and biomarkers of inflammation. Sleep (2009) 2.73
Mild cognitive impairment and alzheimer disease: patterns of altered cerebral blood flow at MR imaging. Radiology (2009) 2.70
Risk factors for mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 2. Arch Neurol (2003) 2.70