Published in Nat Methods on May 01, 2006
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Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry. ACS Chem Biol (2012) 0.95
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Identification of the amino acid sequence that targets peroxiredoxin 6 to lysosome-like structures of lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 0.93
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CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation. Blood (2011) 0.87
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RBC barcoding allows for the study of erythrocyte population dynamics and P. falciparum merozoite invasion. PLoS One (2014) 0.86
A CD25⁻ positive population of activated B1 cells expresses LIFR and responds to LIF. Front Immunol (2011) 0.86
Diverse phosphorylation patterns of B cell receptor-associated signaling in naïve and memory human B cells revealed by phosphoflow, a powerful technique to study signaling at the single cell level. Front Cell Infect Microbiol (2012) 0.85
Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans. Cell Syst (2016) 0.84
Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma. BMC Cancer (2015) 0.84
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Cellular barcodes for efficiently profiling single-cell secretory responses by microengraving. Anal Chem (2012) 0.83
Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity. Mol Ther (2017) 0.83
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Lipopolysaccharides with acylation defects potentiate TLR4 signaling and shape T cell responses. PLoS One (2013) 0.83
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Multifarious determinants of cytokine receptor signaling specificity. Adv Immunol (2014) 0.83
Real-time monitoring of immobilized single yeast cells through multifrequency electrical impedance spectroscopy. Anal Bioanal Chem (2014) 0.82
A Simple, Versatile Antibody-Based Barcoding Method for Flow Cytometry. J Immunol (2016) 0.82
Facts and fiction: cellular models for high throughput screening for HIV-1 reactivating drugs. Curr HIV Res (2011) 0.82
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Fluorescence anisotropy (polarization): from drug screening to precision medicine. Expert Opin Drug Discov (2015) 0.79
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Exposure to a histone deacetylase inhibitor has detrimental effects on human lymphocyte viability and function. Cancer Immunol Res (2014) 0.79
Causal protein-signaling networks derived from multiparameter single-cell data. Science (2005) 34.28
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (2011) 15.45
Computational solutions to large-scale data management and analysis. Nat Rev Genet (2010) 6.58
Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell (2004) 6.24
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat Biotechnol (2011) 5.46
Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity (2012) 5.26
viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nat Biotechnol (2013) 4.88
Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry A (2003) 4.45
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell (2008) 4.06
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Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms. Blood (2010) 3.41
Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nat Rev Cancer (2006) 3.24
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Normalization of mass cytometry data with bead standards. Cytometry A (2013) 2.63
Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1. Nat Immunol (2003) 2.58
High-content single-cell drug screening with phosphospecific flow cytometry. Nat Chem Biol (2007) 2.54
Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Nat Biotechnol (2002) 2.43
Chemical combination effects predict connectivity in biological systems. Mol Syst Biol (2007) 2.42
Structural linkage between ligand discrimination and receptor activation by type I interferons. Cell (2011) 2.39
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Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood (2006) 2.32
From single cells to deep phenotypes in cancer. Nat Biotechnol (2012) 2.12
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proc Natl Acad Sci U S A (2010) 2.10
Chemical labeling strategies for cell biology. Nat Methods (2006) 2.05
Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. Immunity (2010) 2.05
Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (2006) 2.03
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. Blood (2006) 1.93
Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. J Immunol (2005) 1.93
The initial phase of an immune response functions to activate regulatory T cells. J Immunol (2009) 1.88
Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. J Immunol (2006) 1.72
Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML. Cell Stem Cell (2012) 1.71
A platinum-based covalent viability reagent for single-cell mass cytometry. Cytometry A (2012) 1.69
Characterization of the murine immunological signaling network with phosphospecific flow cytometry. J Immunol (2005) 1.65
The transcriptional landscape of αβ T cell differentiation. Nat Immunol (2013) 1.61
Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. Cancer Res (2008) 1.58
Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nat Methods (2006) 1.40
Single-cell phospho-protein analysis by flow cytometry. Curr Protoc Immunol (2007) 1.38
Flow cytometric analysis of kinase signaling cascades. Methods Mol Biol (2004) 1.38
Phospho-proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single-cell level. Immunol Rev (2006) 1.38
Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back. Am J Med Genet A (2010) 1.36
Single-cell mass cytometry for analysis of immune system functional states. Curr Opin Immunol (2013) 1.35
In vivo targeting of organic calcium sensors via genetically selected peptides. Chem Biol (2004) 1.35
Single-cell mass cytometry adapted to measurements of the cell cycle. Cytometry A (2012) 1.33
Activation of the PKB/AKT pathway by ICAM-2. Immunity (2002) 1.31
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Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Blood (2006) 1.23
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